Control track and group visibility more selectively below.
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| Mouse methylome studies |
| Mouse methylome studies |
| SRP540228 |
| The spatial zonation of the placental vasculature is specified by epigenetic mechanisms [WGBS] [SRS22973605, SRS22973606, SRS22973607, SRS22973608, SRS22973609, SRS22973610] |
| SRP534659 |
| Erosion of somatic tissue identity with loss of the X-linked intellectual disability factor KDM5C [Embryonic Stem Cell, Extended Epiblast-Like Cell] |
| SRP531904 |
| The DNA demethylase TET1 modifies the impact of maternal folic acid status on embryonic brain development [E11.5 Brain] |
| SRP526448 |
| Epigenetic regulators of clonal hematopoiesis control CD8 T cell stemness during immunotherapy [Bisulfite-Seq] [CD8 T Cells] |
| SRP526206 |
| Tet3 regulates terminal cell differentiation at the metabolic level [E18.5 Isolated Villi] |
| SRP522281 |
| Early Moderate Prenatal Alcohol Exposure and Maternal Diet Impact Offspring DNA Methylation Across Species [Brain, Liver] |
| SRP521804 |
| Dnmt3a Controls Hematopoietic Stem Cells via DNA Methylation-Independent Regulation of Telomeres [BM, KSL] |
| SRP521262 |
| Whole genome bisulfite sequencing of mice treated by mitochondrial transplantation [Brain, Muscle] |
| SRP511326 |
| CXXC5 stabilizes DNA methylation patterns in mouse embryonic stem cells [Bisulfite-Seq] [mESC] |
| SRP503857 |
| Mutant IDH1 inhibition induces reverse transcriptase and dsDNA sensing to activate tumor immunity [mouse WGBS] [Liver Cells, Tumor Cells] |
| SRP501862 |
| Conserved epigenetic hallmarks of T-cell aging during immunity and malignancy [CD8 T Cells] |
| SRP500539 |
| Maternal obesity induces the meiotic defects and epigenetic alterations during fetal oocyte development [BiSulfite-seq] [Primordial Germ Cells] |
| SRP498773 |
| GEO accession GSE262843 is currently private and is scheduled to be released on Jul 01, 2025. [CD8 T Cells] |
| SRP490016 |
| Methylation status of CD4+ and CD11b+ cells from Dnmt3a+/+ or Dnmt3aR878/+ mice [CD11b+ Cells, CD4+ Cells] |
| SRP487504 |
| Sex-Specific DNA Methylation and Gene Expression Changes in Mouse Placentas After Early Preimplantation Alcohol Exposure[Methyl-Seq] [Placenta] |
| SRP484966 |
| Antisense transcription can induce expression memory via stable promoter repression [XX ESCs] |
| SRP478001 |
| Global epigenetic stability of liver-resident invariant natural killer T cells in response to cues capable of inducing transcriptional re-programming [Liver iNKT (aGalCer/CD1d Tetramer+)] |
| SRP477968 |
| Extraembryonic gut endoderm cells undergo programmed cell death elimination during development (WGBS) [Extraembryonic Endoderm (Distal), Extraembryonic Endoderm (Proximal), Hindgut Endoderm, Midgut Endoderm, Yolk Sac Endoderm] |
| SRP476050 |
| Cohesin trajectories shape the epigenetic and transcriptional landscape of clustered Protocadherin genes for single neuron identities [Olfactory Epithilium] |
| SRP474956 |
| Transcriptomic and epigenomic profiling of Tet TKO neural stem cells to study NSC specification and multipotency [Embryonic Stem Cells, Neural Stem Cells] |
| SRP474495 |
| Landscape of TFs binding in mouse early embryos [Bisulfite-seq] [Early 2Cell] |
| SRP473623 |
| Mus musculus strain:C57Bl/6J Raw sequence reads [Placenta, Primordial Germ Cells] |
| SRP473050 |
| Source cell-type epigenetic memory persists in induced pluripotent cells but is lost in subsequently derived germline cells [Embryonic Fibroblasts, Embryonic Stem Cells, Induced Pluripotent Stem Cells, Primordial Germ Cell Like Cells, Primordial Germ Cells, Spermatogonial Stem Cells, Tail Tip Fibroblasts] |
| SRP472167 |
| FoxA1/2-dependent epigenomic reprogramming drives lineage switching in lung adenocarcinoma [Bisulfite-Seq] [Lung, Lung Tumors] |
| SRP471571 |
| Histone methyltransferase SETDB1 silenced SINE B2 retrotransposons and maintained mitotic cell cycle of neural progenitor cells (WGBS) [Neural Progenitor Cells] |
| SRP469813 |
| Whole Genome Bisulphite Sequencing of undifferentiated and differentiated NIH3T3L1 [SRS19388092, SRS19388093, SRS19388094, SRS19388095] |
| SRP466337 |
| Astrocyte-produced HB-EGF limits autoimmune CNS pathology [WGBS] [FACS-sorted Astrocyte] |
| SRP463129 |
| Genome-wide DNA methylation pattern changes in ESC, and EPSC after treated with T09 [EPSC, EPSC With T09, ESC, NrESC] |
| SRP462875 |
| Mus musculus Genome sequencing and assembly [Liver] |
| SRP461642 |
| Whole genome bisulfite sequencing identifies stage- and subtype-specific DNA methylation signatures in pancreatic cancer [Normal Pancreatic Ductal Organoid, PanIN Organoid, Pancreatic Ductal Adenocarcinoma Organoid] |
| SRP460843 |
| Whole genome bisulfite sequencing (WGBS) of intestinal organoids from mice with graft-versus-host disease [Intestinal Organoids] |
| SRP458075 |
| DNA methylation shapes the Polycomb landscape during the transition from naïve-to-primed pluripotency [Embryonic Stem Cells] |
| SRP456835 |
| DNMT3A Addback [Bone Marrow] |
| SRP455338 |
| Durable and efficient gene silencing in vivo by hit-and-run epigenome editing [WGMS_invitro_revision] [Hepatocyte] |
| SRP454736 |
| Sperm DNA methylation defects in a new mouse model of the 5,10-methylenetetrahydrofolate reductase 677C>T variant and correction with moderate dose folic acid supplementation. [Sperm] |
| SRP451433 |
| Combinational effect of the ADD domains of DNMT3A and DNMT3L on DNA methylation landscapes in mouse germ cells [WGBS] [Fully Grown Oocyte, Sperm] |
| SRP450385 |
| Catalytic dependent and independent roles of Tet3 in activation of ectodermal and silencing of mesodermal programs during neuroectoderm specification [Neuroectoderm Cells] |
| SRP447781 |
| GEO accession GSE236722 is currently private and is scheduled to be released on Jul 06, 2025. [LUAD, Melanoma] |
| SRP447137 |
| Single cell methylation, RNA, and ATAC sequencing of brain tissue in inbred mouse strains [Brain] |
| SRP441169 |
| HDAC6 deacetylates IDH1 to regulate the homeostasis of hematopoietic stem/progenitor cells [WGBS-seq] [Hematopoietic Stem/Progenitor Cells (LSK)] |
| SRP440315 |
| Transcriptomic and methylomic analyses of liver tissue in nonalcoholic steatohepatitis [Bisulfite-Seq] [Liver] |
| SRP435461 |
| Cell-specific and shared regulatory elements control a multi-gene locus active in mammary and salivary glands [Bisulfite-seq] [Liver, Mammary Gland] |
| SRP435424 |
| Genome-wide methylated CpG status in WT and IRF8KO microglia [WGBS] [FACS-sorted Microglia] |
| SRP433931 |
| Prenatal exposure to benzo[a]pyrene depletes ovarian reserve and masculinizes embryonic ovarian germ cell transcriptome transgenerationally [Bisulfite-Seq] [Primordial Germ Cell] |
| SRP432324 |
| Macrophage recipient WGBS data: Donors infected with Porphyromonas gingivali (WDPg) or sham-infected (WD) and fed a western diet (WD) [Elicited Macrophages] |
| SRP431846 |
| Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities [WGBS] [Somatosensory Cortex] |
| SRP431160 |
| Whole genome bisulfite-seq analysis of control and Dnmt3a conditional knockout (cKO) retinal ganglion cells at 2 days post optic nerve crush [Retinal Ganglion Cell] |
| SRP426653 |
| Stem Cell Activity-Coupled Suppression of Endogenous Retrovirus Governs Adult Tissue Regeneration [WGBS] [Anagen Hair Follicle Cells] |
| SRP425335 |
| Epigenetic evolution of the Ly49 gene family [Bisulfite-Seq] [Natural Killer Cells] |
| SRP425083 |
| T regulatory cells epigenetic changes in food induced anaphylaxis animal model after immunotherapy. [T Regulatory Cells] |
| SRP424820 |
| Durable and efficient gene silencing in vivo by hit-and-run epigenome editing [WGMS] [Hepatocyte] |
| SRP423445 |
| Ultrafast Bisulfite Sequencing for Efficient and Accurate 5-Methylcytosine Detection in DNA and RNA [Plasma, Stem Cell, mESC] |
| SRP422816 |
| Distinct disease mutations in DNMT3A result in a spectrum of behavioral, epigenetic, and transcriptional disruptions [Cortex] |
| SRP422554 |
| Predicting age in single cells and low coverage DNA methylation data [scBS] [Whole Blood Depleted Of Red Blood Cells] |
| SRP421061 |
| DNA methylation in the mouse cochlea promotes maturation of supporting cells and contributes to the failure of hair cell regeneration [Inner Ear Cochlea] |
| SRP418871 |
| Dynamic DNA methylation turnover at the exit of pluripotency epigenetically primes gene regulatory elements for hematopoietic lineage specification [WGBS] [ESC, EpiLC] |
| SRP417480 |
| Inducible disruption of Tet genes results in myeloid malignancy, readthrough transcription, and a heterochromatin-to-euchromatin switch [WGBS] [CD11b+] |
| SRP417057 |
| Whole-genome bisulfite sequencing analysis for intestinal budding organoids derived from induced or tissue-derived intestinal stem cells, and for mouse embryonic fibroblasts [Embryonic Fibroblast (MEF), Intestinal Stem Cell (ISC)] |
| SRP414189 |
| TET activity propagates transcriptional memory through embryonic dormancy [WGBS] [Embryonic Stem Cell] |
| SRP413488 |
| Methylation state of latent and proliferative metastatic tumor cells [Breast Cancer] |
| SRP412252 |
| Epigenetic changes in food induced anaphylaxis animal model after immunotherapy. [Dendritic Cells] |
| SRP410496 |
| Whole genome bisulfite sequencing and Infinium Mouse Methylation BeadChip using fresh and fresh-frozen mouse epidermis (WGBS) [Epidermis] |
| SRP407097 |
| Sex Chromosomes and Sex Phenotype Contribute to Biased DNA Methylation in Mouse Liver [Liver] |
| SRP405928 |
| Optimized bisulfite sequencing reveals the lack of 5-methylcytosine in mammalian mitochondrial DNA [WGBS] [Brain, Breast Cancer Cell, Embryonic Kidney Cell, Embryonic Stem Cell, Hepatocarcinoma Cell, Lung Adenocarcinoma Cell, Melanoma Cell, Neuroblastoma Cell, Platelet] |
| SRP405758 |
| Comparative analysis of epigenomic evolution in mammals [Liver, Skeleton Muscle] |
| SRP404930 |
| LN-stem, tumor stem, tumor terminally differentiated CD8 T cells from human kidney cancer [CD8 T Cell, Endo CD8 T Cell, P14 CD8 T Cell] |
| SRP403116 |
| Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation [Liver] |
| SRP401089 |
| Dual gene activating and repressive functions of TET1 in germ layer lineage bifurcation distinguished by genomic context and dependence on 5-methylcytosine oxidation [oxWGBS] [CM59, CM69, KO1, KO15, WT34, WT7, WT70, WT72] |
| SRP400331 |
| DNA methyltransferase inhibition induces dynamic gene expression changes in lung CD4+ T cells of neonatal mice with E. coli pneumonia [RRBS] [CD4+ T Cell] |
| SRP400320 |
| Whole genome bisulfite sequencing (WGBS) and RNA-sequencing of preadipocytes from iWAT [Preadipocytes (CD45-, CD31-, TER119-, PDGFRa+)] |
| SRP400264 |
| WGBS WT J1 ESC at D3 of EpiLC differentiation [Embryonic Stem Cells] |
| SRP399723 |
| Zmym2 is essential for methylation of germline genes and active transposons in embryogenesis [WGBS-seq] [Whole Embryo] |
| SRP399252 |
| p16 epimutation modulates the tumor microenvironment and promotes malignancy of Apc-mutant colon cancer [Embryonic Fibroblast] |
| SRP398703 |
| Prenatal exposure to benzo[a]pyrene depletes ovarian reserve and masculinizes embryonic ovarian germ cell transcriptome transgenerationally I [Primordial Germ Cell] |
| SRP398698 |
| Prenatal exposure to benzo[a]pyrene depletes ovarian reserve and masculinizes embryonic ovarian germ cell transcriptome transgenerationally II [Primordial Germ Cell] |
| SRP398560 |
| Whole-genome bisulfite sequencing and histone 3.3 ChIP-seq of microdissected developing mouse lens [Embryonic Lens Epithelium, Embryonic Lens Fiber] |
| SRP398423 |
| TET2 lesions enhance the aggressiveness of CEBPA-mutant AML by rebalancing GATA2 expression [WGBS] [AML Blasts] |
| SRP397538 |
| Tet2 regulates Sin3a recruitment at active enhancers in embryonic stem cells [Embryonic Stem Cells] |
| SRP397149 |
| Basal cell extrusion primes pluripotent cells for differentiation [Embryo, Pluripotent Stem Cells] |
| SRP396513 |
| Rockfish: Detection of 5mC DNA Modifications Using Raw Nanopore Signal [Embryonic Stem Cell, Purified Cardiomyocyte] |
| SRP396130 |
| NSD1 deposits Histone H3 lysine 36 dimethylation to pattern non-CG DNA methylation in neurons [WGBS in vivo] [Cerebral Cortex] |
| SRP396119 |
| NSD1 deposits Histone H3 lysine 36 dimethylation to pattern non-CG DNA methylation in neurons [WGBS in vitro] [Cultured Cortical Neurons] |
| SRP395892 |
| DNA dioxygenases Tet2/3 control epithelial differentiation (bisulfite-seq) [Hair Matrix Keratinocytes] |
| SRP395725 |
| Tet2 and Tet3 mediated active cytosine hydroxymethylation in Six2 progenitor cells is critical for nephron progenitor differentiation and nephron endowment [Nephron Progenitor] |
| SRP393405 |
| scNMT-seq of the adult NSC lineage - MAB-seq [Adult Neural Stem Cells And Astrocytes, Neuroblasts, Oligodendrocytes] |
| SRP393350 |
| Whole genome enzymatic methyl-seq of A20 mouse cells using a novel TETact activation of CD4 [A20 B Cell Lymphoma Cell Line] |
| SRP388748 |
| Transcriptional and epigenetic reprogramming mediated by chronic IL1ß exposure drives self-renewal ability and myeloid priming in TET2 deficient stem and progenitor cells [Bisulfite-Seq] [Common Myeloid Progenitor, Granulocyte-Macrophage Progenitor, LSK Progenitor Cell] |
| SRP388596 |
| Decitabine-induced T cell remodeling facilitates a high antitumor response to PD-1 blockade therapy by promoting the expansion and effector function of CD8+ progenitor exhausted T cells [CD8+ T Cells] |
| SRP387245 |
| Differences in DNA methylation of HAMP in blood cells predicts the development of type 2 diabetes [WGBS] [Liver] |
| SRP384348 |
| Evidence that direct inhibition of transcription factor binding is the prevailing mode of gene and repeat repression by DNA methylation [WGBS-Seq] [Ebryonic Stem Cells, Embryonic Kidney Cells, Ngn2_neurons] |
| SRP381882 |
| In vivo loss of TET2 and TET2 results in aberrant differentiation and homeostasis in the small intestine [Colon Epithelial Cells] |
| SRP379742 |
| The intrinsic and extrinsic effects of Tet proteins during gastrulation [Sorted Ctrl1 Cells, Sorted Ctrl2 Cells, Sorted TKO1 Cells, Sorted TKO2 Cells] |
| SRP378380 |
| WGBS data of enhanced addictive bahavior in male offspring [Brain-Nucleus Accumbens] |
| SRP377658 |
| Genome-wide assessment of DNA methylation alterations induced by superovulation, sexual immaturity and in vitro follicle growth in mouse blastocysts [Blastocyst] |
| SRP376940 |
| Temporally-Divergent Regulatory Mechanisms Govern Neuronal Diversification and Maturation in the Neocortex [WGBS] [Somatosensory Cortex And Motor Cortex] |
| SRP376633 |
| H3K36 methylation maintains cell identity by regulating opposing lineage programs [Reprogramming Intermediate] |
| SRP376172 |
| DNA sequence determines epigenetic bistability at imprinting control regions [WGBS] [Embryonic Stem Cells] |
| SRP375715 |
| Role of Dppa3 during primordial germ cell development II [Fully Grown Oocyte (FGO)] |
| SRP373182 |
| TRIM28 establishes skeletal stem cell identity and safeguards skeletogenesis (WGBS) [Rib Caritilage Cells] |
| SRP372616 |
| Global DNA methylation analysis of mouse totipotent potential stem cells, extended pluripotent stem cells and mouse embryonic stem cells [Embryonic Stem Cells, Extended Pluripotent Stem Cells, Totipotent Potential Stem Cells] |
| SRP371845 |
| Raw WGBS reads of mice zygotes [Oocyte, Sperm, Zygotes] |
| SRP371705 |
| MethylC-Seq: Intestinal stem cell aging signature reveals a reprogramming strategy to enhance regenerative potential [Intestinal Stem Cell (ISC)] |
| SRP370019 |
| Disturbance on DNA methylation and gene expression levels of mouse plasma leukocytes by low-dose ionizing radiation [Plasma Leukocyte] |
| SRP368317 |
| Genome-wide methylation analysis of murine CD4+ Th1, Th2, and Th17 cells [CD4+ Memory T Cell] |
| SRP367910 |
| Inflammatory exposure drives permanent impairment of hematopoietic stem cell self-renewal activity and accelerated aging |
| SRP367742 |
| HIV Tat and cocaine interactively alter genome-wide DNA methylation and gene expression and exacerbate learning and memory impairments [Bisulfite-seq] [Brain Hippocampus] |
| SRP367683 |
| TET2 and TET3 loss disrupts small intestine differentiation and homeostasis [Bisulfite-seq] [Small Intestine] |
| SRP367185 |
| Spatial organization of H3K9me2/3-marked heterochromatin is redundantly maintained by either the H3K9 or H3K27 methylation pathway [MethylC-seq] [iMEFs] |
| SRP366957 |
| Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration [WGBS] [Cortex] |
| SRP364004 |
| Transcriptional regulation of the thymus master regulator Foxn1 [WGBS] [Thymus Epithelial Cell Type 1, Thymus Epithelial Cell Type 2, Thymus Epithelial Cell Type 3, Thymus Epithelial Cell Type 4, Type II Airway Epithelial Cells] |
| SRP363630 |
| Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet [mESC] |
| SRP363476 |
| Dynamic antagonism between key repressive pathways maintains the placental epigenome (WGBS) [Trophoblast Stem Cells] |
| SRP362787 |
| Genome-wide bisulfite sequencing (GWBS) and RNA-seq in hippocampus of Neil1- and Neil2 deficient mice [Hippocampus] |
| SRP361168 |
| Suppression of colorectal cancer by ketogenic diet and beta-hydroxybutyrate (Bisulfite Sequencing Dataset) [Colon] |
| SRP360425 |
| Role of Dppa3 during primordial germ cell development I [Primordial Germ Cell (PGC)] |
| SRP360183 |
| Whole genome bisulfite sequencing of WT and Dnmt3a KO HSCs following chronic infection [Hematpoietic Stem Cells] |
| SRP359332 |
| Donor T-cell DNMT3a regulates alloreactivity in murine models of hematopoietic stem cell transplantation [WGBS] [Sorted Splenic Donor T-cells] |
| SRP357383 |
| DNA methylation landscape and transcriptome of tumor-associated macrophages reveals pathways, transcription factors, and prognostic value relevant for breast cancer patients [methylation] [Bone Marrow-Derived Monocytes, Mammary Gland Macrophages, Tumor-associated Macrophages] |
| SRP356163 |
| PU.1-dependent enhancer inhibition separates clonal hematopoiesis from malignant transformation (oxBS-Seq) [cKit+ Lymph- Ery- HSPC] |
| SRP355886 |
| Whole-genome bisulfite sequencing (WGBS) of stressed and nonstressed breast tumor in mice [Breast Tumor] |
| SRP355808 |
| Somatic Dnmt3a deletion in murine hematopoietic cells [B-cells, CMP, GMP, KLS, MEP, Myeloid, T-cells, WBM] |
| SRP354658 |
| Global DNA methylation analysis of cancer-associated fibroblasts reveals extensive epigenetic rewiring linked with RUNX1 upregulation in breast cancer stroma [WGBS] [Non-immune Stromal Cells] |
| SRP353283 |
| Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors [Not Applicable] |
| SRP353039 |
| WGBS of control and DAC-treated CT26 cells. [CRC Cell Line CT26] |
| SRP351503 |
| Cell-type specific DNA methylome signatures reveal epigenetic mechanisms for neuronal diversity and neurodevelopmental disorder [GABAergic Neurons, Glutamatergic Neurons, Purkinje Neurons] |
| SRP351062 |
| Whole genome DNA methylation profiling of mouse nucleus accumbens Drd2 medium spiny neurons by using two independent library preparation methods [D2-MSN] |
| SRP350997 |
| GLP is critical for oogenesis exhibiting a G9A-independent role in transcriptional repression [Oocyte] |
| SRP350023 |
| Vitamin C deficiency causes cell type-specific epigenetic reprogramming and acute tubular necrosis [Kidney] |
| SRP349681 |
| The distinct effects of MEK and GSK3 inhibition upon the DNA methylome and transcriptome of mouse embryonic stem cells [Embryonic Stem Cells] |
| SRP348783 |
| Sex-specific epigenetic development in the mouse hypothalamic arcuate nucleus pinpoints human genomic regions associated with body mass index [Glia, Neuron] |
| SRP342995 |
| H3K36 Dimethylation Shapes the Epigenetic Interaction Landscape by Directing Repressive Chromatin Modifications in Embryonic Stem Cells |
| SRP342917 |
| Rat and mouse imprintomes (allele-specific DNA methylomes) [EPC, Epiblast] |
| SRP342595 |
| Dynamics of DNA hydroxymethylation and methylation during mouse embryonic and germline development [IVC Epiblast] |
| SRP342588 |
| Whole genome bisulfite sequencing of 3T3-L1 preadipocytes and adipocytes [Embryo] |
| SRP342541 |
| Maternal SMCHD1 controls both imprinted Xist expression and imprinted X chromosome inactivation [Embryo] |
| SRP342398 |
| Next Generation Sequencing Facilitates Quantitative Analysis of ApoE-/-/SAHHWT, ApoE-/-/SAHH+/- mice and ApoE-/-/SAHH+/- +Betaine mice [WGBS] [Vascular] |
| SRP341070 |
| Promoter repression and 3D-restructuring resolves divergent developmental gene expression in TADs [WGBS] [ESC, Limb] |
| SRP340739 |
| Loss of TET reprograms Wnt signaling through impaired demethylation to promote lung cancer development [Lung] |
| SRP339793 |
| Somatic Dnmt3a deletion in murine hematopoietic cells [B-cells, CMP, GMP, Lineage Negative Kit Positive Sca1 Positive, MEP, Myeloid Cells, T-cells, Whole Bone Marrow] |
| SRP339237 |
| CaBl: MSL2 is an allelic dosage sensor in mammals [Neural Progenitor Cells] |
| SRP339236 |
| BlCa: MSL2 is an allelic dosage sensor in mammals [Neural Progenitor Cells] |
| SRP339235 |
| 9sCa: MSL2 is an allelic dosage sensor in mammals [Neural Progenitor Cells] |
| SRP337411 |
| Examining age-dependent DNA methylation patterns and gene expression in the male and female mouse hippocampus [Dorsal Hippocampus] |
| SRP337056 |
| The DNMT1 inhibitor GSK-3484862 mediates global demethylation in murine embryonic stem cells [Undifferentiated Embryonic Stem Cells] |
| SRP336812 |
| Differential regulation of mouse hippocampal gene expression sex differences by chromosomal content and gonadal sex: Whole Genome OXBS-Seq Data [Hippocampus] |
| SRP336725 |
| Histone H3K36me2 and H3K36me3 form a chromatin platform essential for DNMT3A-dependent DNA methylation in mouse oocytes [Oocyte] |
| SRP336573 |
| Perturbation of TET2 condensation induces genome-wide promiscuous DNA hypomethylation and curtails leukemia cell growth [Embryonic Stem Cells (mESCs), Leukemia Cell Line] |
| SRP336168 |
| Tet2 deficiency altered hematopoietic stem and progenitor cells ageing process [LSK] |
| SRP336016 |
| Salt induces hepatic inflammatory response through epigenetic modulation of SIRT3 [Bisulfite-seq] [Liver] |
| SRP331841 |
| DNA Methylation Status in Mouse Liver Affected by Maternal High-fat, High-sucrose diet [Liver] |
| SRP329853 |
| Mouse methylome and transcriptome of three brain tissues in aging [Hippocampus, Striatum, Substantia Nigra] |
| SRP329752 |
| Whole genome bisulfite sequencing (WGBS) analysis of murine splenic DC subtypes [Not Applicable] |
| SRP329327 |
| HypoSUMOylation in embryonic stem cells generates head-and-trunk embryo-like structure [Methyl-seq] [ES Cells] |
| SRP327113 |
| DNA methylation changes of heart tissue in mouse with alcoholic cardiomyopathy [Heart] |
| SRP325428 |
| Systematic profiling of DNMT3A variants reveals protein instability mediated by the DCAF8 E3 ubiquitin ligase adaptor [Embryonic Stem Cells, Lymphoblastoid Cell Line] |
| SRP323244 |
| Tet enzymes are required for mammalian embryonic hematopoiesis [Endothelial Cell, Hematopoietic Stem And Progenitor Cell] |
| SRP322748 |
| Club cells employ regeneration mechanisms during lung tumorigenesis [Lung] |
| SRP321876 |
| Genetic variation at mouse and human ribosomal DNA influences associated epigenetic states [Blood, Kidney] |
| SRP321573 |
| Conservation and divergence of DNA methylation patterns and functions in vertebrates [Primary Dermal Fibroblasts, Psoas Muscle] |
| SRP319425 |
| Whole-genome bisulfite sequencing anlaysis of in vitro fertilized mouse hybrid blastocysts [Blastocyst] |
| SRP319090 |
| Whole genome bisulfite sequencing analysis to examine the effect of the iron chelator deferoxamine on DNA methylation levels in 3T3-L1 pre-adipocyte cells [Preadipocyte Cell Line] |
| SRP318894 |
| RNA-seq, WGBS, 5hmC-Seal, and ATAC-seq data about TET proteins and skeletal development (WGBS) [Primary Osteoblasts] |
| SRP315002 |
| Functional and epigenetic phenotypes of humans and mice with DNMT3A overgrowth syndrome [Whole_Bone_Marrow] |
| SRP314467 |
| Postnatal expansion of the lymph node stromal cell pool towards reticular and CD34+ stromal cell subsets [WGBS] [Gut-Draining Mesenteric Lymph Node, Skin-Draining Mesenteric Lymph Node] |
| SRP313733 |
| Whole genome bisulfite sequencing of young and old satellite cells [Primary Myoblasts] |
| SRP313387 |
| Regnase-1 suppresses TCF-1+ precursor exhausted T cell formation to limit CAR T cell responses against ALL [WGBS] [Regnase-1-deficient CAR T, WT CAR T] |
| SRP313361 |
| Whole Genome Bisulfite Sequencing of miR-143 knock-out mice liver [MIGS Eukaryotic Sample From] |
| SRP312798 |
| Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineages [ExE (Extraembryonic Ectoderm)] |
| SRP312491 |
| Placenta and fetal brain share a neurodevelopmental disorder DNA methylation profile in a mouse model of prenatal PCB exposure [WGBS] [Brain, Placenta] |
| SRP312013 |
| Maintenance DNA methylation in pre-meiotic germ cells regulates meiotic prophase by facilitating homologous chromosome pairing [Male Germ Cells] |
| SRP311975 |
| A cis-acting mechanism mediates trancriptional memory at Polycomb target genes in mammals [WGBS] [C-Myc-Immortalized Embryonic Fibroblasts] |
| SRP310416 |
| Dnmt3a-Mutant Hematopoietic Stem cells are resistant to inflammatory stress [Donor Derived CD45.2 Cells] |
| SRP310260 |
| Mouse totipotent stem cells captured and maintained through spliceosomal repression [mESC Cultured In SLP Medium, mESC Cultured In Serum/Lif Medium] |
| SRP309709 |
| Epigenetic integrity of paternal imprints enhances the developmental potential of androgenetic haploid embryonic stem cells [Haploid mESCs] |
| SRP309644 |
| DNMT3B supports meso-endoderm differentiation from mouse embryonic stem cells [WGBS] [ES-E14, ES-E14 Derived EpiSC, EpiLC-derived ME] |
| SRP309373 |
| RNA-seq, ATAC-seq, WGBS, and CUT&RUN of urothelial cells isolated from Naive, Resolved, and Sensitized C3H/HeN mice [Urothelial Stem Cells (USCs)] |
| SRP309253 |
| In Vitro Reconstitution of the Whole Male Germ-Cell Development from Mouse Pluripotent Stem Cells [PBAT] [Germ Cells Derived] |
| SRP309189 |
| Genome-wide methylation analysis of murine innate lymphoid cells [Innate Lymphoid Cells] |
| SRP308731 |
| Loss of SETD1B results in the redistribution of genomic H3K4me3 in the oocyte [PBAT] [Germinal Vesicle Oocytes] |
| SRP308565 |
| Methylomes of young and aged LT-HSCs [Primary Hematopoietic Stem Cells] |
| SRP307526 |
| DNA methylation regulates haematopoietic development [AGM, Bone Marrow, Fetal Liver] |
| SRP305480 |
| 5-hydroxymethylcytosine is required for terminal differentiation of Purkinje neurons [Purkinje Cells] |
| SRP302337 |
| ZFP57 dictates allelic expression switch of target imprinted genes [Total Embryo] |
| SRP302195 |
| Whole genome bisulfite sequencing of sstr2 knockout mice [Gastric Tissue] |
| SRP302177 |
| Whole genome bisulfite sequencing of E13.0 and E13.5 Tex14 mutant, heterozygote and wild-type murine female germ cells [Germ Cell] |
| SRP301916 |
| Constitutive loss of DNMT3A causes morbid obesity through misregulation of adipogenesis [Adipose] |
| SRP300442 |
| Disordered N-Terminal DNMT3A Domain Is Required for Mouse Postnatal Development [Cerebral Cortex, Cortical Neuron Nuclei] |
| SRP300086 |
| PDGFRa+ not CD137+ progenitors control visceral obesity via glucocorticoid mediated TEAD1 methylation state [Adipose Progenitors] |
| SRP300044 |
| Genome-wide maps of DNA methylome during oocyte aging and its transgenerational inheritance [Hippocampus, M2 Oocyte, Sperm] |
| SRP299927 |
| Methylomes of macrophage-DC progenitors (MDPs), monocytes, common monocyte progenitors (cMoPs), common dendritic cell progenitors (CDPs), plasmacytoid dendritic cells (pDCs), and cDC CD8a+ as well as cDC CD11b+ dendritic cells [CDPs, MDPs, Monocytes, cDC CD11b+, cDC CD8a+, cMoPs, pDCs] |
| SRP297921 |
| Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation [II] [Small Intestinal Epithelium Derived Organoids] |
| SRP297323 |
| Base-editor-mediated multiplexed inactivation of DNA methyltransferases reveals essential roles of miRNAs in mouse gastrulation [Epiblast, Extraembryonic Ectoderm, Whole Embryo] |
| SRP296451 |
| WGBS on prospermatogonia at E18.5 |
| SRP294136 |
| Unraveling the functional role of DNA demethylation at specific promoters by targeted steric blockage of DNA methyltansferase with CRISPR/dCas9 [NIH-3T3] |
| SRP292910 |
| The effect of NEIL3 on CA1 DNA methylation [Brain] |
| SRP292755 |
| KMT2C Loss Promotes Small Cell Lung Cancer Metastasis through DNMT3A-mediated Epigenetic Reprogramming [Liver, Lung] |
| SRP292587 |
| TET deficiency promotes oncogenesis and DNA damage in B cells by increasing the levels of G-quadruplexes and R-loops [WGBS] [B Cells] |
| SRP292265 |
| Cell type-specific transcriptomic and eipgenome analysis of diabetic cardiomyopathy [Cardiac Myocyte, Endothelial Cell, Fibroblast, Macrophage] |
| SRP291379 |
| Dnmt3a deficiency in the skin [Skin] |
| SRP291181 |
| Transgenerational inheritance of epigenetic signatures at CpG islands in mice [ESC] |
| SRP289560 |
| Whole-genome bisulfite sequencing analysis of Pten's function in regulating cardiomyocyte differentiation [ES-derived Cardiomyocytes] |
| SRP289001 |
| Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation [Fibroblast] |
| SRP288067 |
| Epigenomic profiles of 4T1 cell line in primary, metastasis site and circulating cell type in xenograft mouse model [Circulating Tumor Cell, Fat Pad Xenograft, Lung Metastasis, Mammary Gland] |
| SRP288034 |
| DNA methylomes of murine B and T cells from the BLUEPRINT Epigenome project [CD4+CD62L+ T Cells, CD43- B Cells] |
| SRP286409 |
| H3K27me3 shapes DNA methylome by inhibiting UHRF1-mediated H3 ubiquitination [Bisulfite-seq] [E14, HeLa] |
| SRP286191 |
| Genome-wide maps of Dnmt1-dependent DNA methylome in adipocytes [Adipocytes] |
| SRP285604 |
| Muscle regeneration controlled by a designated DNA dioxygenase (Methylation-Seq) [Satellite Cells Derived Myoblasts] |
| SRP285138 |
| Dnmt1 has global de novo methylation activity and is specifically targeted to transposable elements [E3.5 Blastocyst, E6.5 Epiblast, mESC] |
| SRP283863 |
| Foxp3 enhancers synergize to maximize regulatory T cell suppressive capacity [Bisulfite-Seq] [FACS Sorted Regulatory T Cells (CD4+GFP+)] |
| SRP282126 |
| MicroRNA-29 is an essential regulator of non-CG methylation during brain maturation [Bisulfite-seq] [Cortex] |
| SRP282002 |
| Sperm epigenetic alterations contribute to inter- and transgenerational effects of paternal exposure to long-term psychological stress via evading offspring embryonic reprogramming [Embryo, Sperm] |
| SRP281855 |
| YY1 safeguard multidimensional epigenetic landscape associated with extended pluripotency [EPS Cells] |
| SRP280273 |
| Fetal origin of sex-bias brain aging [Fetal Brain, Placenta] |
| SRP278195 |
| Whole genome bisulfite sequencing analysis to measure the effect of EHMT2 (G9a, Bat8) on DNA methylation in the mouse embryo at 9.5 dpc [Embryo] |
| SRP273620 |
| Whole genome bisulfite sequencing of apoptotic and male-differentiated subpopulations of E13.5 wild-type murine male germ cells [Apoptosis-poised (AP) Germ Cell, Male-differentiated (MD) Germ Cell] |
| SRP273163 |
| Atg7-dependent autophagy regulates the naive to primed transition by selective Nanog degradation in mouse embryonic stem cells [WGBS] [E14TG2] |
| SRP272852 |
| Epigenetic reprogramming of airway macrophages drives polarization and inflammation in muco-obstructive lung disease (WGBS_BL) [Airway Macrophages] |
| SRP271992 |
| Methylation and gene expression data obtained from Dnmt3b+/+, Dnmt3bD/D and Dnmt3bCI/CI MYC induced T-cell lymphomas (MTCLs). [Lymph Node] |
| SRP271532 |
| Formative pluripotent stem cells show features of epiblast cells poised for gastrulation [MethylC_fPSCs_P10] |
| SRP271469 |
| Methylation and gene expression data obtained from Dnmt3b+/- peripheral T-cell lymphomas. [Lymph Node] |
| SRP271091 |
| Glucocorticoids sensitive progenitor PDGFRa+ cells switching to white adipocytes cause visceral obese via methylation modification of TEAD1 (Bisultite-seq) [Adipose Progenitors] |
| SRP270999 |
| Hoxa10 is a functional positional memory that governs stem cell function in adult skeletal muscle [Masseter, Tibialis Anterior] |
| SRP267967 |
| Characterization of universal features of partially methylated domains across tissues and species [Breast Tumor, Lung] |
| SRP267895 |
| Multiomics profiling of young and old quiescent skeletal muscle stem cells [aging WGBS] [Skeletal Muscle Stem Cells] |
| SRP266608 |
| Mouse preimplantation imprinting [WGBS] [Blastocyst, Embryonic Stem Cell, Kidney] |
| SRP266415 |
| Flanking sequence preference modulates de novo DNA methylation in the mouse genome [Embryonic Stem Cells] |
| SRP265512 |
| Temporal evolution of cellular heterogeneity during the progression to advanced, AR-negative prostate cancer [RRBS] [Tumor] |
| SRP265261 |
| Cyclosporin A and FGF signaling support the proliferation/survival of mouse primordial germ cell-like cells in vitro [bis-seq] [E9.5 PGC, ESC] |
| SRP265159 |
| IGF2R-initiated Proton Rechanneling Dictates an Anti-inflammatory Property in Macrophages [Peritoneal Macrophages] |
| SRP261529 |
| An activity-mediated transition in transcription in early postnatal neurons [BS-seq] [Cortex] |
| SRP261467 |
| Epigenetic and chromatin profiling of wild-type and Dnmt3a-deficient B1 and B2 B cells. (methylation) [B1, B2, proB1, proB2] |
| SRP258472 |
| Neuronal activation modulates enhancer activity of genes for excitatory synaptogenesis through de novo DNA methylation [Cultured Hippocampal Neurons (10DIV)] |
| SRP258361 |
| Transgenerational inheritance of obesity correlates with transmission of epigenetic alterations in the Fto gene [BS-seq] [Sperm] |
| SRP257778 |
| Characterization of metabolic patterns in mouse oocytes during meiotic maturation [MII Oocytes] |
| SRP257737 |
| Role of E2F6 in gene expression and DNA methylation during mouse development [E8.5 Whole Embryos] |
| SRP257580 |
| Altered microRNA expression links IL6 and TNF-induced inflammaging with myeloid malignancy [miR146aKO_LSK_WGBS] [Bone Marrow] |
| SRP255391 |
| NSD1-deposited H3K36me2 directs de novo methylation in the mouse male germline and counteracts Polycomb-associated silencing [E16.5 Prospermatogonia, P0 Prospermatogonia] |
| SRP254904 |
| DNMT3A haploinsufficiency results in behavioral deficits and global epigenomic dysregulation shared across neurodevelopment disorders [Bisulfite-Seq] [Cortex] |
| SRP254510 |
| Mus musculus musculus strain:Bl6 Raw sequence reads [Enterocytes] |
| SRP254051 |
| Post-implantation developmental defects induced by mtDNA mutation derive from altered DNA methylome in oocytes [D257A Treated Oocyte, Wild Type Oocyte] |
| SRP252412 |
| WGBS and RNA-seq of mouse livers and human Hep3B cells [Liver] |
| SRP251304 |
| Control of Foxp3 induction and maintenance by sequential histone acetylation and DNA demethylation [WGBS] [Wild-type CD4 Effector T Cells, Wild-type Naive CD4 T Cells, Wild-type Regulatory T Cells] |
| SRP250290 |
| A multivalent signal-transducing model for the DNMT1-mediated maintenance DNA methylation [ES Cells] |
| SRP247347 |
| TET2 promotes anti-tumor immunity by governing G-MDSCs and CD8+ T cell numbers |
| SRP246939 |
| Beta cell-specific CD8+ T cells maintain stem-cell memory-associated epigenetic programs during type 1 diabetes (WGBS) [HAART HIV TN CD8 T Cells, Polyclonal Naive CD8 T Cell HD, Polyclonal T1D Naive CD8 T Cells, Polyclonal TCM CD8 T Cells, Polyclonal TEM CD8 T Cells, Polyclonal TSCM CD8 T Cells, Tetramer+ CD8 T Cells, Tetramer+ HAART CD8 T Cells, Tetramer+ T1D CD8 T Cells] |
| SRP246664 |
| Autocrine IL6 activates the STAT3-DNMT axis to silence the TNFa-RIP1 necroptosis pathway to sustain myeloid-derived suppressor cell survival and accumulation [CD11b+Gr1+] |
| SRP246238 |
| Disturbed mitochondrial dynamics in CD8+ TIL reinforce epigenetic programming linked with T cell exhaustion |
| SRP244650 |
| Paradoxical whole genome DNA methylation dynamics of Decitabine in chronic low-dose exposure in mice [Liver, Testes] |
| SRP242612 |
| Whole Genome Bisulfite Sequencing of CD4+ T cells from mice developmentally exposed to vehicle or TCDD prior to and during influenza infection [CD4+ T Cells] |
| SRP242576 |
| Epigenetic changes in Langerhans islets preceding the onset of diabetes [Islet] |
| SRP239769 |
| DNA methylome analysis of directly induced oocyte-like cells (DIOLs) [Embryonic Stem Cells, Fully-grown Directly Induced Oocyte-Like Cells, Non-growing Directly Induced Oocyte-Like Cells] |
| SRP239280 |
| Structural basis of epigenetic protection of mouse lymphoid progenitor cells by Dnmt1 [Mouse WGBS] [Lin- Bone Marrow Progenitors] |
| SRP239190 |
| DNMTs Play an Important Role in Maintaining the Pluripotency of Leukemia Inhibitory Factor Dependent Embryonic Stem Cells [Embryonic Stem Cell] |
| SRP237267 |
| Maternal DNMT3A-dependent de novo methylation of the zygotic paternal genome inhibits gene expression in the early embryo [BB_androgenetic_blasto_DNAme, BD_2C_Dnmt3aMatKO_DNAme, BD_2C_Dnmt3aMatWT_DNAme] |
| SRP234989 |
| Transcriptomic and epigenetic disruptions in excitatory neurons in Dnmt3a conditional knockout mouse [Excitatory Pyramidal Neurons] |
| SRP234410 |
| Whole Genome Bisulfite Sequencing Facilitates Quantitative Analysis of DNA Methylation status in sperm from 2 month old and 18 month old mice [Sperm] |
| SRP233665 |
| The role of Vitamin C and TET dioxygenases in genome-wide features of regulatory T cells [WGBS] [Spleen And Lymph Nodes] |
| SRP230428 |
| Tet2 negatively regulates memory fidelity [CA1 Hippocampal Tissue] |
| SRP230210 |
| Whole genome bisulfite sequencing (WGBS) of Tex15 wt, Tex15 ht, and Tex15 ko male germ cells at postnatal day 2.5 [Germ Cells] |
| SRP229636 |
| Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia: Whole Genome oxidative bisulfite sequencing data [Brain] |
| SRP229373 |
| Novel Isoforms of the Epigenetic Regulator TET1 Differentially Control CNS Synaptic Function, Plasticity, and Cognition [Cultured Hippocampal Neurons] |
| SRP229336 |
| DeepH&M: Simultaneous determination of single-CpG hydroxymethylation and methylation levels from enrichment and restriction enzyme sequencing methods [Cerebellum, Cortex] |
| SRP227031 |
| EED is required for Mouse Primordial Germ Cell Differentiation in the Embryonic Gonad [Primordial Germ Cells] |
| SRP223513 |
| G9a plays distinct roles in maintaining DNA methylation, retrotransposon silencing and chromatin looping [Embryonic Stem Cell] |
| SRP223436 |
| Unique Transcription Factor Functions Regulate Epigenetic and Transcriptional Dynamics During Cardiac Reprogramming [alphaMHC-GFP+ Sorted Induced Cardiomyocytes, dsRed+ Sorted Fibroblasts (Control Infection)] |
| SRP222566 |
| Whole genome bisulfite Sequencing data of four types mouse spermatogenesis [Differentiated Spermatogonia Cells, Pachytene Spermatocytes, Round Spermatids, Undifferentiated Spermatogonia Cells] |
| SRP222128 |
| Genome-wide analysis of methylated DNA in control and Tet2/Tet3-deficient B cells [Primary B Cells] |
| SRP221485 |
| Epigenetic regulator function through mouse gastrulation [Extraembryonic Ectoderm, Proximal Epiblast] |
| SRP219391 |
| Maternal exposure to a mitochondrial toxicant results in life-long alterations in DNA methylation and gene expression in the offspring [Liver] |
| SRP217940 |
| Bivalent promoter hypermethylation in cancer is linked to the H327me3/H3K4me3 ratio in embryonic stem cells [ES Cells] |
| SRP216390 |
| Epigenetic and transcriptional changes in aging mouse rod photoreceptors [WGBS] [Rod Photoreceptors] |
| SRP215028 |
| Paradoxical association of TET loss of function with genome-wide hypomethylation [iNKT] |
| SRP214596 |
| Dnmt3a and Dnmt3b-mediated decommissioning of fetal enhancers linked to kidney disease [Kidney] |
| SRP212622 |
| Profiling of DNA Methylation during RANKL Induced Osteoclastogenesis using Whole-Genome Bisulfite Sequencing [Bone Marrow] |
| SRP201955 |
| Analysis of dendritic cell differences [Bone Marrow] |
| SRP199205 |
| Tox reinforces the phenotype and longevity of exhausted T-cells in chronic viral infection [Bisulfite-Seq] [P14 T-cells] |
| SRP198282 |
| Hammer-seq to measure kinetics of DNA methylation maintenance in HeLa cells [Embryonic Stem Cell, Epithelial Adenocarcinoma] |
| SRP195507 |
| Genome-wide roles of DNA methyltransferases in mouse embryos [Whole Embryos] |
| SRP194541 |
| Whole genome bisulfite genome analysis of OX40L-Jagged-1 expanded Treg and Teff cells [CD4+CD25-Teff Cells, CD4+CD25hi Treg Cells] |
| SRP193267 |
| Allelic histone-to-DNA methylation switch establishes secondary DMR to maintain noncanonical imprinting [E6.5 Extraembryonic Ectoderm] |
| SRP192143 |
| Setd2 deficiency impaired erythroid differentiation and accelerated Myelodysplastic Syndrome(MDS) - associated leukemogenesis through S100A8 and S100A9 [C-Kit+ Cells, Hematopoietic Stem And Progenitor Cells (HSPCs)] |
| SRP191868 |
| Genome-wide analysis of DNA methylation profile in astrocytes isolated from naïve mice or EAE mice transduced with astrocyte-specific Mafg-targeting or non-targeting lentiviruses [WGBS] [Flow Cytometry Sorted Astrocytes] |
| SRP189864 |
| Uncoupling histone H3K4 trimethylation from developmental gene expression via an epigenetic equilibrium of Polycomb, COMPASS and DNA methylation [Embryonic Stem Cell] |
| SRP188734 |
| Downregulation of Uhrf1 activity by TGF-ß signaling controls Foxp3 methylation and iTreg cell differentiation [CD4+ T Cells] |
| SRP188205 |
| MeCP2 represses the rate of transcriptional initiation of highly methylated long genes (BS-Seq and OxBS-Seq) [Forebrain Tissue] |
| SRP187205 |
| Methylome profiling of GADD45 deficient mouse embryonic stem cells [Embryonic Stem Cells (mESC)] |
| SRP186720 |
| Association Between Early Life DNA Methylation Patterns with Age-Related Transcriptional Changes [Hippocampus] |
| SRP186642 |
| Genome-wide methyl-cytosine competition by DNMT and TET [ESCs, Embryonic Stem Cell, EpiSCs, HUES64, HUES8, HUES8 Embryonic Stem Cells, In Vitro Derived Motor Neurons] |
| SRP186631 |
| Epigenetic signatures of chronic social stress in stress-susceptible animals [Nucleus Accumbens] |
| SRP185738 |
| Characterization of the DNA methylome in embryonic retina, retinal progenitors, and RGCs [Retina] |
| SRP185723 |
| WGBS of WT and Smchd1-KO ES cells [Embryonic Stem Cells] |
| SRP184524 |
| RNA m6A modification mediated by METTL3 is important for IAP heterochromatin integrity in mESCs (WGBS) [Embryonic Stem Cells] |
| SRP183094 |
| The intestinal microbiota programs DNA methylation to control tissue homeostasis and inflammation [BiSulfite-seq] [Colon Epithelial Cells] |
| SRP178652 |
| Branched-chain Amino Acid Aminotransferase-1 Regulates Self-Renewal and Pluripotency of Mouse Embryonic Stem Cells through Ras Signaling [mES] |
| SRP176417 |
| Single cell multi-omics analysis reveals novel roles for DNA methylation in sensory neuron injury responses [DRG Sensory Neuron] |
| SRP174993 |
| ChIP-seq and RNA-seq analysis of histone Kcr in the embryonic forebrain and neural stem/progenitor cells. [Forebrain] |
| SRP174666 |
| Super-enhancer subregions highly bound by the nuclear receptor ESRRB regulate the exit from naïve pluripotency [Epiblast Stem Cells (EpiSCs)] |
| SRP174491 |
| FoxA-dependent demethylation of DNA initiates epigenetic memory of cellular identity [Hepatocytes] |
| SRP174255 |
| Effects of combined treatment of EGCG and environmental enrichment on postnatal mouse cortex regulome [Homogenate] |
| SRP174096 |
| Endogenous retroviral insertions drive non-canonical imprinting in extra-embryonic tissues [Bisulfite-Seq] [Epiblast, Extra-embryonic Ectoderm] |
| SRP173926 |
| Loss of non-CpG methylation in inhibitory neurons impairs neural function through a mechanism that partially overlaps with Rett syndrome [Inhibitory Neurons] |
| SRP173239 |
| DNA methylation estimation using methylation-sensitive restriction enzyme bisulfite sequencing (MREBS) [Embryonic Fibroblasts, Embryonic Stem Cells] |
| SRP172778 |
| GR mutation in mice changes the genome-wide epigenome of frontal cortex in a highly sex-specific manner [Frontal Cortex] |
| SRP171165 |
| Transcriptonal and epigenetic changes of adult liver cells in vivo and in vitro [Adult DDC Damaged Liver, Adult Healthy Liver] |
| SRP170065 |
| Differential roles of Stella in the modulation of DNA methylation during oocyte and zygotic development [Female Pronucleus, Male Pronucleus, Oocyte] |
| SRP168427 |
| Tet inactivation disrupts YY1 binding and long-range chromatin interactions to cause developmental defects in embryonic heart [Embryonic Heart] |
| SRP168393 |
| DNA methylation in AgRP neurons regulates voluntary exercise behaviour in mice [Neuron] |
| SRP168345 |
| Characterization of the DNA methylome in murine Müller glia [Glast+ Cells] |
| SRP167718 |
| Next Generation Sequencing Combined Analysis of DNA Methylome and Transcriptome Reveal Novel Candidate Genes of Neuroprotective with Response to Ischemic Preconditioning [Brain] |
| SRP167689 |
| WGBS in wild-type and MommeD1mut MEFs [MEFs] |
| SRP165997 |
| Dynamic enhancer partitioning instructs Zdbf2 activation during epigenetic reprogramming [bisulfite-seq] [Epiblast-like Cell] |
| SRP163215 |
| Aging of mouse spermatogonial stem cells by Wnt7b-Jnk pathway activation [Bisulfite-seq] [Testis] |
| SRP162771 |
| Characterization of the DNA methylome in retinal pigment epithelium (RPE) of adult mice [Retinal Pigment Epithelium (RPE)] |
| SRP162035 |
| Activin A and BMP4 Signaling Expands Potency of Mouse Embryonic Stem Cells in Serum Free Media [Embryonic Stem Cell, Epiblast Stem Cell] |
| SRP161525 |
| True 5-methylcytosine profiling of late reprogramming stages during in vitro reprogramming of mouse embryonic fibroblasts (MEFs) to induced pluripotent stem cells (iPSCs) [Day 0 Embryonic Fibroblasts, Day 10 Totalx2 mCherry+/GFP+, Day 10 Totalx2 mCherry+/GFP-, Day 12 Naivex2 mCherry+/GFP+, Day 12 Naivex2 mCherry+/GFP-, Day 14 Naivex2 mCherry+/GFP+, TET1 KO iPSC Clonal Line, Experiment 1, TET1 KO iPSC Clonal Line, Experiment 2, Wild-Type iPSC Clonal Line, Experiment 1, Wild-Type iPSC Clonal Line, Experiment 2] |
| SRP160386 |
| Perturbation of the OGT-TET1 interaction in mouse embryonic stem cells (WGBS) [Tet1 D2018A Mutant Knock In Stem Cells, Wild Type Stem Cells] |
| SRP159665 |
| WGBS (Whole Genome Bisulfite Sequencing) of Wild-type and Math5-/- mouse dLGN (dorsolateral geniculate nucleus) at postnatal day 6 and postnatal day 23 [dLGN (Dorsolateral Geniculate Nucleus)] |
| SRP159191 |
| Long-range epigenetic concordance revealed by simultaneous profiling of DNA methylation and chromosomal conformation changes in bulk and single cell Methyl-HiC [ESC Line] |
| SRP158977 |
| Methylome assays of E14.5 pancreatic progenitor cells [Endocrine Enrichment] |
| SRP158409 |
| H3K36me2 recruits DNMT3A and shapes intergenic DNA methylation landscapes [C3H Embryo-Derived Mesenchymal Progenitor Cells] |
| SRP156779 |
| DNA hypermethylation encroachment at CpG island borders in cancer is predisposed by H3K4 monomethylation [mESC_WGBS] [Embryonic Stem Cells] |
| SRP156136 |
| MethMotif: An integrative cell specific database of transcription factor binding motifs coupled with DNA methylation profiles [Colon, Spleen] |
| SRP155404 |
| A DNMT3A PWWP mutation leads to methylation of bivalent chromatin and postnatal growth retardation in mice [Epiblast, Hypothalamus, Liver] |
| SRP154996 |
| Epigenetic changes of the thioredoxin system in the tx-j mouse model and in patients with Wilson disease [Fetal Liver] |
| SRP154319 |
| Effects of environmental enrichment on postnatal mouse cortex regulome [Homogenate] |
| SRP151725 |
| Imprecise DNMT1 activity coupled with neighbor-guided correction enables robust yet flexible epigenetic inheritance [mESC, mESC-derived Cell] |
| SRP151590 |
| Integrated Genomic Analysis of a Stem Cell Model of Overgrowth Syndrome with Intellectual Disability (WGBS) [J1 ESC, J1 NSC] |
| SRP151137 |
| DNA methylation oscillations at CpG poor enhancers in primed embryonic stem cells [scRNA-Seq, scBS-Seq] [Embryo] |
| SRP151020 |
| Inhibition of aberrant DNA re-methylation improves development of cloned embryos (WGBS-Seq) [Cumulus Cell, Embryonic Fibroblast Cell, Nuclear Transfer Embryo, Sertoli Cell] |
| SRP149052 |
| Single-Cell RNA-Seq Reveals Dynamic Early Embryonic-like Programs during Chemical Reprogramming [CiPSCs, Intermediate Cells, XEN-like Cells] |
| SRP142028 |
| Mus musculus Epigenomics [Embryonic Fibroblasts (MEFs)] |
| SRP139795 |
| Transient reduction of DNA methylation at the onset of meiosis in male mice [Testis] |
| SRP139083 |
| DNA 5-methylcytosine specific profiling with limited input [ESCs] |
| SRP136786 |
| Bisulfite-free direct detection of 5-methylcytosine and 5-hydroxymethylcytosine at base resolution [E14 Embryonic Stem Cells] |
| SRP136449 |
| Comprehensive analysis of H3K9me2 oocytes, together with DNA methylation and expression analysis of G9a conditional KO oocytes and maternal KO preimplantation embryos [2-Cell Embryos, Blastocysts, Fully Grown Oocytes] |
| SRP136419 |
| WGBS assessment of global methylation alterations in Dnmt3a1KO , Dnmt3a2KO, Dnmt3aKO, Tet1KO and DKO mouse embryonic stem cells [Embryonic Stem Cells] |
| SRP136257 |
| Mammalian ISWI and SWI/SNF selectively mediate binding of distinct groups of transcription factors (Bis-seq data sets) [Embryonic Stem Cells] |
| SRP135700 |
| Transcriptional and Epigenomic Landscapes of CNS and non-CNS Vascular Endothelial Cells [Vascular Endothelial Cells] |
| SRP133698 |
| Global DNA methylation remodeling during direct reprogramming from fibroblast to neuron [MethylC-seq] [Direct Reprogramming, Embryonic Fibroblast, Neural Progenitor Cells] |
| SRP133565 |
| Genome-wide identification of distinct target loci for de novo DNA methylation by DNMT3A and DNMT3B during mammalian development [MEFs] |
| SRP133323 |
| Extensive recovery of embryonic enhancer and gene memory stored in hypomethylated enhancer DNA. [Embryonic Epithelial Cells, Intestinal Villus Cells] |
| SRP132683 |
| DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries [Embryonic Stem Cells] |
| SRP131922 |
| Analysis of genetically diverse macrophages reveals local and domain-wide mechanisms that control transcription factor binding and function [Bone Marrow Derived Macropages (BMDM)] |
| SRP130993 |
| SCNT embryos are defective for H3K27me3 imprinting [RNA-seq] |
| SRP127792 |
| Single-cell dissection of long non-coding RNAs pivotal for embryonic hematopoietic stem cell development [T1 pre-HSC] |
| SRP127685 |
| Setd2 deficiency impairs hematopoietic stem cell self-renewal and causes malignant transformation [Bone Marrow LSK Cells] |
| SRP126875 |
| Differences in cell cycle status underlie transcriptional heterogeneity in the HSC compartment [HSC] |
| SRP125690 |
| Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and synaptic plasticity [Dentate Gyrus] |
| SRP125421 |
| Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B cell programming [Bisulfite-Seq-Cre] [Ebf1-deficient B Cell Progenitors] |
| SRP125320 |
| Effector CD8 T cells dedifferentiate into long-lived memory cells [Acute GP33-specific CD8 T Cells, Acute Memory Precursor P14 Cells, Acute Terminal Effector P14 Cells, P14 CD8 T Cells] |
| SRP125227 |
| Next Generation Sequencing for Genome-wide Maps of DNA Methylaton in mES Cells [Embryonic Stem Cells] |
| SRP123612 |
| Novel Principles of Cellular Reprogramming Revealed by Prospective Isolation and Characterization of Rare Intermediates Poised to Generate iPSCs [WGBS] [MEF, Reprogramming Intermediate, iPSC] |
| SRP123210 |
| Genetics, sex and life experience influence DNA methylation in the mouse [Liver] |
| SRP119705 |
| DNA hypermethylation encroachment at CpG island borders in cancer is predisposed by H3K4 monomethylation [WGBS_Mm] [Blood (B Cell-Depleted), Spleen Bulk B Cells] |
| SRP119366 |
| Long genes linked to autism harbor intragenic super-enhancer-like chromatin domains [Cortical Excitatory Neurons] |
| SRP119143 |
| Transcriptomic and epigenomic analysis during conversion from mouse microglia into induced-neuronal (iN) cells [Microglial Cells] |
| SRP118911 |
| High-Resolution Dissection of Conducive Somatic Cell Reprogramming to Naïve Ground State Pluripotency in Mbd3/NuRD and Gatad2a/NuRD Depleted Systems [WGBS] [Gatad2a-/- Cell Line, Mbd3f/- Cell Line, WT Cell Line] |
| SRP117079 |
| Transcription factors drive Tet2-mediated enhancer demethylation to reprogram cell fate [Bisulfite-Seq] [Cultured Primary Cells (Short Term), Embryo (Inner Cell Mass), Low Passage (P<10)] |
| SRP116554 |
| Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex [Cerebral Cortex] |
| SRP116373 |
| Early-life gene expression in neurons modulates lasting epigenetic states. [Bisulfite-seq] [Cortex, Hippocampus] |
| SRP115607 |
| A role of Polycomb in the maintenance of hypomethylation for DNA methylation valley [mESCs] |
| SRP113606 |
| Transient and permanent reconfiguration of chromatin and transcription factor occupancy drive reprogramming [Day12 MEF Reprogramming Intermediates, Day3 MEF Reprogramming Intermediates, Day6 MEF Reprogramming Intermediates, Day9 MEF Reprogramming Intermediates, MEF, MEF Derived Induced Pluripotent Stem Cells] |
| SRP113417 |
| Chromatin and Transcriptional Dynamics in Adult Germline Stem Cells and Mammalian Spermatogenesis [Mature Sperm, Sperm, Spermatids, Spermatocytes, Spermatogonia, Spermatogonia (Thy1+)] |
| SRP113409 |
| Transcriptional and epigenetic profiling of aged mouse SVZ-derived neural stem / progenitor cells [SVZ-derived Neural Stem / Progenitor Cells] |
| SRP113186 |
| Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency. [ESCs] |
| SRP111470 |
| Whole genome bisulfite sequencing of mouse neural progenitor cells and neurons from the mouse cerebral cortex at day 15.5 of embryonic development [Cortical Neurons, Neural Progenitor Cells] |
| SRP111384 |
| rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline [WGBS] [Whole Testis] |
| SRP111382 |
| WGBS assessment of global methylation alterations in Dnmt3aKO or Dnmt3bKO mouse embryonic stem cells [Embryonic Stem Cells] |
| SRP111167 |
| DNA methylation dynamics during embryonic development and postnatal maturation of the auditory organ of Corti [Organ Of Corti] |
| SRP110902 |
| DNMT3A haploinsufficiency predisposes hematopoietic cells to myeloid malignancies [Bone Marrow] |
| SRP109867 |
| Base-resolution analysis of DNA methylation patterns downstream of Dnmt3a in mouse naïve B cells [Naive B Cells] |
| SRP109785 |
| Paternal cold exposure enhances brown adipose tissue sensitivity in offspring and ameliorates diet induced obesity [Sperm] |
| SRP109758 |
| Cytosine methylation dynamics during spermatogenesis and post-testicular sperm maturation [Caput Sperm, Cauda Sperm, Corpus Sperm, Early Round Spermatids, Later Round Spermatids, Primary Spermatocytes, Vas Deferens Sperm] |
| SRP108476 |
| Whole genome bisulfite sequencing of Ing1/Gadd45a double knockout and wildtype mouse embryonic fibroblasts [Embryonic Fibroblasts (MEFs)] |
| SRP108349 |
| Enhancing the Potency of Mouse Embryonic Stem Cells [BS-Seq] [Embryonic Stem Cells] |
| SRP108295 |
| De novo epigenetic programs inhibit PD-1 blockade-mediated T-cell rejuvenation [WGBS] [Antigen-specific CD8 T Cells, Naive CD8 T Cells] |
| SRP106356 |
| Activation of Lineage-Regulators and Transposable Elements Across a Pluripotent Spectrum [2I – N2B27_BL6, 2i/LIF – GMEM/10% KSR_BL6, 2i/LIF – GMEM/10% Serum_129, 2i/LIF – N2B27_BL6, Ch/LIF – N2B27_BL6, Pd/LIF – N2B27_BL6, Serum/LIF -GMEM_129, Serum/LIF – Feeders - GMEM_BL6] |
| SRP105270 |
| Reprogramming of H3K9me3-dependent heterochromatin during mammalian early embryo development [WGBS] [4-Cell Embryo, 6.5 Day Embyo Epiblast, 6.5 Day Embyo Extraembryonic Ectoderm, 7.5 Day Embyo Epiblast, 7.5 Day Embyo Extraembryonic Ectoderm, 8-Cell Embryo, Early 2-Cell Embryo, Inner Cell Mass, Late 2-Cell Embryo, Morula Embro, Trophoblast, Zygote] |
| SRP105210 |
| Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells in vivo [WGBS] [Hematopoietic Stem Cells] |
| SRP103763 |
| Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the mouse brain [Cerebellum, Cortex, Olfactory Bulb] |
| SRP103077 |
| Mapping DNA methylation and CTCF/cohesin occupancy on nascent chromatin and DNMT-targeted nascent chromatin [Embryonic Stem Cells] |
| SRP101774 |
| Isoform-specific localization of DNMT3A regulates DNA methylation fidelity at bivalent CpG islands [WGBS] [Embryonic Stem Cells] |
| SRP101591 |
| Simultaneous mapping of active DNA demethylation and sister chromatid exchange in single cells [Around 100 Embryonic Stem Cells, E14] |
| SRP101453 |
| Environmental enrichment increases transcriptional and epigenetic differentiation between mouse dorsal and ventral dentate gyrus neurons [Brain (Dentate Gyrus Of The Hippocampus)] |
| SRP101416 |
| Whole-genome bisulfite-seq (WGBS) on Lin-Sca1+Kit+ (LSK) bone marrow cells from wild-type C57BL/6J mice [Lin-Sca1+Kit- Cells] |
| SRP100972 |
| 5-hydroxymethylcytosine Accumulation in Postmitotic Neurons Results in Functional Demethylation of Expressed Genes [MethylC-Seq and oxBS-Seq] [Cerebellar Granule Cells] |
| SRP099067 |
| The BLUEPRINT Murine Lymphocyte Epigenome Reference Resource. [Whole Genome Bisulfite-Seq_OX] [From CD4+CD62L+ T Cells, From CD43- B Cells] |
| SRP099066 |
| The BLUEPRINT Murine Lymphocyte Epigenome Reference Resource. [Whole Genome Bisulfite-Seq] [CD4+CD62L+ T Cells, CD43- B Cells] |
| SRP099007 |
| Microglia isolated from juvenile offspring of dams with allergic asthma exhibit methylation and transcriptional alterations to autism risk genes [WGBS] [Acutely Isolated Microglia, P35 Brain] |
| SRP097617 |
| MLL2 conveys transcription-independent H3K4me3 in the oocyte [Germinal Vesicle Oocytes] |
| SRP097054 |
| DNA methylation of SAMP8 and SAMR1 mice [Cerebral?Cortex] |
| SRP095627 |
| DNA methylomes at base resolution of mouse embryonic fibroblasts in G1 and G2 phase of cell cycle [Embryonic Fibroblasts (MEFs)] |
| SRP095235 |
| Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism [Liver] |
| SRP094653 |
| ncRNA transcription-induced changes in nuclear architecture directs with high precision enhancer-promoter interaction [In-Vitro DN2 Cells] |
| SRP092540 |
| WGBS assessment of global methylation alterations in hematopoietic stem and progenitor cells [methyl-seq] [Intermediate-Term Hematopoietic Stem Cell, Long-Term Hematopoietic Stem Cell, Multi-Potent Progenitor, Short-Term Hematopoeitic Stem Cell] |
| SRP092247 |
| Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions (WGBS 2) [Hepatocytes] |
| SRP092244 |
| Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions (WGBS 1) [Hepatocytes] |
| SRP091938 |
| Increased H3K9 methylation and impaired expression of Protocadherins are associated with the cognitive dysfunctions of the Kleefstra syndrome [Brain] |
| SRP091011 |
| Tracking of dCas9-methyltransferase footprints [mESCs] |
| SRP090852 |
| Vitamin C induced epigenomic remodeling in IDH1 mutant acute myeloid leukemia [HOXA9 Immortalized Bone Marrow] |
| SRP090698 |
| Epigenetic Memory Underlies Cell Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells [LKS SLAM Cells] |
| SRP090505 |
| DNA methylation profiling of vascular maturation [Endothelial Cells] |
| SRP090249 |
| Whole Genome Bisulfite Sequencing in Pax7-reprogrammed corticotropes AtT-20 cells [Pituitary Corticotroph Cell] |
| SRP090219 |
| The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis [WGBS_Mm] [Derived iPSCs fMG02, Derived iPSCs fMG03, Embryonic Fibroblasts Cell, Embryonic Stem Cell, Immature Retinal-Derived iPSCs 8601, Mature Retinal-Derived iPSCs 3302, Mature Retinal-Derived iPSCs 7602, Retina] |
| SRP090139 |
| Analyzing whole genome bisulfite sequencing data from highly divergent genotypes [Liver] |
| SRP089858 |
| A novel requirement for Drosha in maintenance of mammalian CG methylation [Embryonic Stem Cells (ES Cells)] |
| SRP089825 |
| Enhanced Pluripotent Cell Function through miR-203-mediated Control of DNA Methylation [Ebs, iPs WT Long After DOX, iPs WT Short After DOX, iPs WT T=0, iPs miR-203 KI-N5 (T=0), iPs miR-203 KI-N5 Long After DOX, iPs miR-203 KI-N5 Short After DOX, iPs miR-203 KI-N9 (T=0), iPs miR-203 KI-N9 Long After DOX, iPs miR-203 KI-N9 Short After DOX] |
| SRP083895 |
| Transcription and chromatin determinants of the rate of de novo DNA methylation in oocytes [60-65Um Oocytes] |
| SRP083753 |
| LKB1 loss links the serine metabolic network to DNA methylation and tumourigenesis [bisulfite-seq] [Primary Pancreatic Ductal Epithelial Cells] |
| SRP082360 |
| Epigenetic memory of obesity in mouse colonic epithelium [Colon] |
| SRP081475 |
| Methylomes of wild-type and MeCP2 knockout brain cells [Whole Brain] |
| SRP081312 |
| DNA methylation regulates intron retention via altered MeCP2-mediated splicing factor recruitment [Granulocytes, Promyelocytes] |
| SRP081133 |
| DNA methylation repels binding of hypoxia-inducible transcription factors to maintain tumour immunotolerance [WGBS] [Inner Cell Mass] |
| SRP081004 |
| Postnatal DNA demethylation and its role in tissue maturation [Hepatocyte] |
| SRP080866 |
| DNA methyltransferase 3b regulates articular cartilage homeostasis by altering chondrocyte metabolism [Primary Articular Chondrocytes] |
| SRP078942 |
| Cis-regulatory landscape of four cell types of the retina [Cones, Horizontal Cells, Rods, Starbust Amacrine Cells] |
| SRP078871 |
| Whole genome bisulfite sequencing of adult hypothalamus male mouse brain [Mixed Brain Cells] |
| SRP078848 |
| Whole genome bisulfite and TAB-Sequencing from sorted neurons in the adult mouse brain [NeuN+ Neuronal Nuclei] |
| SRP078445 |
| DNA Methylation Divergence and Tissue Specialization in the Developing Mouse Placenta [Whole Placenta] |
| SRP078328 |
| Epigenetic restriction of embryonic and extraembryonic lineages mirrors the somatic transition to cancer (WGBS) [Extraembryonic Ectoderm, Inner Cell Mass, Precompacted 8 Cell Stage Embryos, Proximal Epiblast, Trophectoderm] |
| SRP078072 |
| Derivation of ground-state female ESCs maintaining gamete-derived DNA methylation [ES Cells] |
| SRP078059 |
| The de novo DNA methyltransferase DNMT3C protects male fertility from transposon activity (Bisulfite-seq). [10 Dpp Total Germ Cells] |
| SRP077894 |
| Single base resolution of the complete 5-mC and 5-hmC cardiac methylome in heart failure [Whole Heart] |
| SRP077875 |
| Allele-Specific Non-CG Methylation Marks Domains of Active Chromatin in Mouse Brain [Brain (Prefrontal Cortex)] |
| SRP076056 |
| Role of Tet proteins in B cell development [Pro B Cells] |
| SRP075981 |
| GEO accession GSE82125 is currently private and is scheduled to be released on May 30, 2017. [ES-derived Neural Progenitor Cells, Embryonic Stem Cells] |
| SRP075309 |
| Mus musculus Epigenomics [ES] |
| SRP074379 |
| Genome-wide map of DNA methylation to unravel the function of EBF1 C-terminus domain [Ebf1-/- c-Kit+ Fetal Liver Cells] |
| SRP074072 |
| WGBS assessment of global methylation alterations in Dnmt3aKO/FLT3-ITD lymphoid leukemia [Leukemic Cells, Thymus Derived CD4/CD8 Double Positive T Cells] |
| SRP071782 |
| Mammalian sperm exhibit epigenetic priming of embryonic and adult regulatory landscapes (BS-Seq) [Sperm] |
| SRP071233 |
| Iron-Heme-Bach1 Axis Is Involved In Erythroblast Adaptation To Iron Deficiency [Erthroblast (Bach1 KO), Erthroblast (WT)] |
| SRP070642 |
| Methylation and gene expression profiling in Dnmt3a-deficient chronic lymphocytic leukemia and peripheral T-cell lymphoma in mice. [Spleen] |
| SRP070637 |
| Single-cell multi-omics sequencing of mouse early embryos and embryonic stem cells [Embryonic Stem Cell] |
| SRP069154 |
| Isoform switch of TET1 regulates DNA demethylation and mouse development [mESCs] |
| SRP069139 |
| ZFP57 maintains the parent-of-origin-specific expression of the imprinted genes and differentially affects non-imprinted targets in mouse embryonic stem cells (BS-seq and RRBS) [Embryonic Stem Cells] |
| SRP069120 |
| Mus musculus strain:C57BL/6 Epigenomics [Liver, MEFs In Culture] |
| SRP068730 |
| Epigenetic reprogramming enables the primordial germ cell-to-gonocyte transition (WGBS) [PGC] |
| SRP068043 |
| Dynamic epigenomic landscapes during early lineage specification in mouse embryos [Ectoderm, Embryonic Stem Cell, Endoderm, Epiblast, Inner Cell Mass, Mesoderm, Primitive Streak, Trophectoderm, Visceral Endoderm] |
| SRP067447 |
| Genetic and Epigenetic Variation, but Not Diet, Shape the Sperm Methylome [Spermatozoa] |
| SRP067341 |
| DNA methylation oscillations at CpG poor enhancers in primed embryonic stem cells [PBAT Bisfulfite-seq] [E14 Embryonic Stem Cell] |
| SRP067094 |
| Chromatin decompaction coupled MuERVL endogenous retrovirus activation induces genome-wide DNA demethylation [E14 Cell Line Untransfected Negative Control, MuERVL+_Zscan4+] |
| SRP066668 |
| genomic DNA from MEF cells [Cultured MEF Cells] |
| SRP065556 |
| Dynamic Changes in Histone Modifications Precede de novo DNA Methylation in Oocytes [Oocyte] |
| SRP065509 |
| Trans-effects of sub-chromosomal duplications on DNA methylation patterns in mouse models of Down syndrome: whole genome bisulfite sequencing of cerebral samples from Dp(10)1Yey and Dp(16)1Yey mouse models. |
| SRP065034 |
| Mus musculus and Mus spretus sperm methylation [Testis] |
| SRP063453 |
| Unique Broad Histone Lysine 4 Methylation Domains in Mouse Oocytes and Dynamic Regulation during Maternal to Zygotic Transition [P12 Oocyte, P15 Oocyte] |
| SRP063275 |
| New roles for DNA cytosine modification, eRNA, anchors and super-anchors in developing B cell progenitors [Rag1 Deficient pro-B, Tcf3(E2A) Deficient pre-pro-B] |
| SRP063093 |
| Acute loss of TET function results in aggressive myeloid cancer in mice [WGBS] [LSK Cells] |
| SRP063015 |
| Epigenomic Landscapes of Retinal Rods and Cones [Rd7 Rod Photoreceptors, WT Cone Photoreceptors, WT Rod Photoreceptors] |
| SRP062705 |
| Whole genome bisulfite sequencing of sperm from a mouse heterozygous for a mutation in Setdb1 (MommeD13) and a wildtype mouse. [Sperm] |
| SRP062575 |
| Genetic and epigenetic variation among inbred littermates: identification of metastable epialleles in the mouse [Adult Liver] |
| SRP062557 |
| DNMT3A and TET2 Compete and Cooperate to Repress Differentiation Lineage-Specific Factors in Hematopoietic Stem Cells [Tet2 Knockout Hematopoietic Stem Cell] |
| SRP062482 |
| TET proteins regulate lineage specification and TCR-mediated expansion of iNKT cells (WGBS) [iNKT Cells] |
| SRP061876 |
| An epigenetic switch ensures transposon repression upon acute loss of DNA methylation in ES cells (WGBS) [J1 WT ES Cell] |
| SRP061339 |
| Sequence Features Accurately Predict Genome-wide MeCP2 Binding in vivo [Olfactory Epithelium] |
| SRP060660 |
| MIWI2 and MILI have differential effects on piRNA biogenesis and DNA methylation |
| SRP060646 |
| De novo DNA methyltransferases DNMT3A and DNMT3B are essential of global DNA methylation maintenance [TAB-Seq] [ES-cells] |
| SRP060643 |
| De novo DNA methyltransferases DNMT3A and DNMT3B are essential of global DNA methylation maintenance [BS-Seq] [ES-cells] |
| SRP059940 |
| Chromatin dynamics and the role of G9a in gene regulation and enhancer silencing during early mouse development [Epiblast Stem Cells, Epiblast-Like Cells] |
| SRP059433 |
| Gender Differences in Global but not Targeted Demethylation in iPSC Reprogramming [BS Seq AIDKO MEF1, BS Seq D21 iPSC Clone3, BS Seq D29 AIDKO iPSC Clone1, BS Seq D29 AIDKO iPSC Clone2, BS Seq D29 MALE iPSC Clone1, BS Seq D29 MALE iPSC Clone2, BS Seq D29 MALE iPSC Clone3, BS Seq D29 iPSC Clone3, BS Seq D6 SSEA1 Positive 1, BS Seq D6 SSEA1 Positive 2, BS Seq D6 SSEA1 Positive 3, BS Seq D6 Thy1 Positive 1, BS Seq D6 Thy1 Positive 2, BS Seq D6 Thy1 Positive 3, BS Seq D60 AIDKO iPSC Clone1, BS Seq D60 MALE iPSC Clone1, BS Seq D60 MALE iPSC Clone2, BS Seq D60 MALE iPSC Clone3, BS Seq D60 iPSC Clone2, BS Seq D60 iPSC Clone3, BS Seq ESC 1, BS Seq ESC 2, BS Seq ESC 3, BS Seq MALE MEF 1, BS Seq MALE MEF 2, BS Seq MALE MEF 3, BS Seq MEF 1, BS Seq MEF 2, BS Seq MEF 3, BS Seq P29 iPSC Clone1, Fibroblast, Reprogramming Fibroblast] |
| SRP057505 |
| Active DNA demethylation at enhancers during the vertebrate phylotypic period [Brain, Sox10+ Cells, Whole Embryo] |
| SRP057157 |
| Competition between DNA methylation and transcription factors determines binding of NRF1 [Embryonic Stem Cells] |
| SRP056705 |
| An epigenetic memory of pregnancy in the mouse mammary gland [Basal Differentiated, Basal Mammary Stem Cells, Basal Progenitor, Luminal Alveolar, Luminal Ductal, Luminal Progenitor, Luminal Total] |
| SRP055147 |
| Maternal DNA methylation regulates early trophoblast development [Trophoblast] |
| SRP052235 |
| HP1 is involved in regulating the global impact of DNA methylation on alternative splicing [R1 Embryonic Stem Cells] |
| SRP050145 |
| An alternative pluripotent state confers interspecies chimaeric competency [WGBS] [E5.75 Derived EpiSCs, E5.75 Derived rsEpiSCs] |
| SRP049965 |
| MORC1 represses transposable elements in the mouse male germ line [Sorted Germ Cells] |
| SRP049936 |
| DNA methylation in mammalian placentas [Cerebrum, Cordblood, Extraembryonic Membrane, Placenta, Trophoblasts] |
| SRP049697 |
| DNA methylation status of Individual 4T1 Clonal Populations [4T1 Mammary Cancer Cell Line, Parental Cell Line] |
| SRP049674 |
| Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain [Brain (Neocortex), Excitatory Pyramidal Neurons, Parvalbumin-Positive (PV) Inhibitory Neurons] |
| SRP049223 |
| Transcription and Imprinting Dynamics in Developing Postnatal Male Germline Stem Cells [Spermatogonia] |
| SRP049191 |
| Single-base resolution analysis of active DNA demethylation using methylase-assisted bisulfite sequencing [E14Tg2A, V6.5] |
| SRP047397 |
| Genome-wide characterization of DNMT-deficient mouse ESCs reveals dynamicity of differentially-methylated-regions and its impact on bivalency composition [ES Cell] |
| SRP047165 |
| Distinct roles of DNMT1-dependent and –independent methylation patterns in the genome of mouse ES cells [Embryonic Stem Cells] |
| SRP045747 |
| Setdb1 is required for persistence of H3K9me3 and repression of endogenous retroviruses in mouse primordial germ cells [SSEA1+ Primordial Germ Cells] |
| SRP045179 |
| Gender-specific post-natal demethylation and establishment of epigenetic memory [Liver] |
| SRP045054 |
| The developmental potential of iPSCs is greatly influenced by the selection of the reprogramming factors [Embryonic Stem Cells, Induced Pluripotent Stem Cells] |
| SRP043370 |
| Tet1 and Tet2 mediate epigenetic regulation of developmental genes by protecting DNA methylation canyons against hypermethylation [Bisulfite-Seq] [Embryonic Fibroblasts] |
| SRP042409 |
| Rlf, a widely-spaced zinc finger protein, is involved in maintaining epigenetic marks at CpG island shores and enhancer elements across the genome [E10.5 Embryo Rep1, E10.5 Embryo Rep2, E14.5 Liver Rep1, E14.5 Liver Rep2, E18.5 Liver Rep1, E18.5 Liver Rep2] |
| SRP042360 |
| Dnmt3L-histone H3 binding is necessary for male fertility and non-CG methylation [DNMT3 A/A, Wild Type] |
| SRP041847 |
| Altered epigenetic programming links intestinal inflammation to colon cancer (Bisulfite-seq) [Colon Epithel] |
| SRP041760 |
| Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation [Bisulfite-Seq] [Embryonic Stem Cells] |
| SRP041376 |
| Tet proteins in DNA demethylation and cell fate restriction [ES Cell Line E14Tg2a] |
| SRP041257 |
| Single-Cell Whole-Genome Bisulfite Sequencing for Analysis of Epigenetic Heterogeneity [ESCs (E14)] |
| SRP041083 |
| Programming and inheritance of parental DNA methylomes in mammals [2-Cell Embryo, 4-Cell Embryo, E13.5 Female PGC, E13.5 Male PGC, E3.5 Embryo, E6.5 Embryo, E7.5 Embryo, Inner Cell Mass, MII Oocyte, Sperm] |
| SRP040627 |
| Imprinted expression is different in visceral yolk sac and cystic embryoid body endoderm [Visceral Yolk Sac Endoderm] |
| SRP040524 |
| CG hypomethylation in Lsh-/- mouse embryonic fibroblasts is associated with de novo H3K4me1 formation and altered cellular plasticity [Cell Line, Primary MEFs] |
| SRP039504 |
| Single base resolution analysis of 5-formyl and 5-carboxyl cytosine reveals the actual promoter DNA methylation dynamics in embryonic stem cells [MAB-Seq] [Embryonic Stem Cells] |
| SRP037785 |
| Two waves of de novo methylation during mouse germ cell development [Germ Cells] |
| SRP034857 |
| Large conserved domains of low DNA methylation maintained by 5-hydroxymethycytosine and Dnmt3a (CMS bisulfite-seq) [Bone Marrow Derived Primary HSCs] |
| SRP033304 |
| The complete methylome of hematopoietic stem cells and their immediate progeny [HSC (LSK, CD34-, CD48-, CD150+), MPP (LSK, CD34+, CD48+, CD150-), MPP1 (LSK, CD34+, CD48-, CD150+), MPP2 (LSK, CD34+, CD48+, CD150+)] |
| SRP033288 |
| Dynamic DNA methylation in cardiac myocyte development, maturation and disease [Cardiac Myocyte, Cardiac Tissue] |
| SRP032967 |
| Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain (Bisulfite-seq) [Dentate Gyrus] |
| SRP029902 |
| Role of de novo DNA methyltransferases in hematopoietic stem cells (WGBS) [Bone Marrow Derived Primary HSCs] |
| SRP029721 |
| Genome-wide regulatory domains and their interactions in Mus musculus [Hematopoetic Stem Cells, Splenic B Cells] |
| SRP028826 |
| Gene expression and chromatin analysis of fused mouse-rat cells [Immortalized Tail Fibroblast] |
| SRP028709 |
| Large conserved domains of low DNA methylation maintained by 5-hydroxymethycytosine and Dnmt3a [Bisulfite-Seq] [Bone Marrow Derived Primary HSCs] |
| SRP026536 |
| 5mC Oxidation by Tet2 Modulates Enhancer Activity and Timing of Transcriptome Reprogramming during Differentiation [Embryonic Stem Cells] |
| SRP026048 |
| Global epigenomic reconfiguration during mammalian brain development [Brain (Cerebral Cortex), Brain (Dorsal Prefrontal Cortex), Brain (Frontal Cortex), Brain (Middle Frontal Gyrus), Embryonic Stem Cells] |
| SRP025996 |
| Maintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (Dnmt3ab KO Methyl-Seq) [Embryonic Stem Cells] |
| SRP025993 |
| Maintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (K9 KO Methyl-Seq) [Embryonic Stem Cells] |
| SRP025152 |
| Epigenetic and genetic changes during mouse hematopoietic stem cell aging [Bisulfite-Seq] [Bone Marrow Derived Primary HSCs] |
| SRP020633 |
| Mus musculus Epigenomics [General Sample From] |
| SRP019026 |
| CG methylated microarrays identify novel methylated sequence bound by the CEBPB|ATF4 heterodimer that are active in vivo [Primary Dermal Fibroblasts] |
| SRP018963 |
| High resolution nulceotide level methylation map of female mouse primary keratinocytes [Primary Keratinocytes] |
| SRP018523 |
| Bisulfite-Seq profiling of undifferentiated ESCs, and in vitro derived primordial germ cells (iPGCs) [ESCs- V6.5, ESCs-Rosa26-GFP, iPGCs, iPGCs-Rosa26-GFP, iPGCs-V6.5] |
| SRP017572 |
| FGF Signaling Inhibition in ESCs Drives Rapid Genome-wide Demethylation to the Epigenetic Ground State of Pluripotency [E14 ES] |
| SRP017503 |
| Tissue-specific methylomes reveal epigenetic memory in adult mouse tissue [Bone Marrow, Cerebellum, Colon, Cortex, Heart, Intestine, Kidney, Liver, Lung, Olfactory Bulb, Pancreas, Placenta, Skin, Spleen, Stomach, Thymus, Uterus] |
| SRP017350 |
| Density and methylation state of CpG dinucleotides define histone variant specific retention of nucleosomes in mouse spermatozoa [Sperm] |
| SRP017139 |
| Dnmt2-dependent methylomes lack biologically relevant DNA methylation patterns [ES Cells] |
| SRP016893 |
| Whole-genome bisulfite sequencing of two distinct interconvertible DNA methylomes of mouse embryonic stem cells [ES-cells] |
| SRP013703 |
| GSE57230: Widespread contribution of transposable elements to the innovation of gene regulatory networks [mouse ENCODE] [Bone Marrow, Cerebellum, Cerebral Cortex, Embryonic Facial Prominence, Forebrain, Heart, Hindbrain, Intestine, Kidney, Large Intestine, Limb, Liver, Lung, Midbrain, Neural Tube, Olfactory Bulb, Small Intestine, Spleen, Stomach, Thymus] |
| SRP013702 |
| Dnmt3a protects active chromosome domains against cancer-associated hypomethylation [Healthy Lung Tissue, Lung Tumors] |
| SRP011945 |
| Base Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome [E14Tg2A, H1] |
| SRP007354 |
| DNA binding factors shape the mouse methylome at distal regulatory regions [BIS_seq] [ES-derived Neuronal Progenitor Cells, Embryonic Stem Cells] |
| SRP004162 |
| Dynamic epigenomic oscillations in differentiated cells |
| ERP155689 |
| Whole Genome Bisulfite Sequencing of CLDN6High vs CLDN6Low Sorted EpiSCs and APSD, and WT vs Pbx1-KO EpiSCs [24H Differentiation, Epiblast Cell] |
| ERP139499 |
| Whole genome bisulfite sequencing of liver samples of five mammals (human, rhesus macaque, mouse, rat and dog) [Liver] |
| ERP138895 |
| Study of a mouse model of angioimmunoblastic T-cell lymphoma [ena-SAMPLE-TAB-05-07-2022-16:18:22:259-81379, ena-SAMPLE-TAB-05-07-2022-16:18:22:259-81380, ena-SAMPLE-TAB-05-07-2022-16:18:22:259-81381, ena-SAMPLE-TAB-05-07-2022-16:18:22:259-81382] |
| ERP130901 |
| Epigenomic rewiring of mouse hippocampus after resistance and endurance exercise training [Hippocampus] |
| ERP128231 |
| CpG island reconfiguration for the establishment and synchronization of polycomb functions upon exit from naive pluripotency [MT-SL WGBS, WT-SL WGBS] |
| ERP126361 |
| DNA methylation profiles of mouse sperm in response to antibiotic-induced gut microbiota dysbiosis using whole-genome bisulfite sequencing [Cauda Epididymal Sperm] |
| ERP120304 |
| Multi-omics characterization of MEK inhibitor resistant pancreatic cancer based on a genetically engineered mouse model-derived in vitro system [1, 2, 3, 4, 6, 7, 8, 9] |
| ERP110807 |
| Methylation_profiles_in_cancer_induced_mouse_liver_tumours [Eea28C50-B5A6-11E8-9Efc-68B59976A384, Eeab22A2-B5A6-11E8-9Efc-68B59976A384, Eeb10690-B5A6-11E8-9Efc-68B59976A384, Eebf133E-B5A6-11E8-9Efc-68B59976A384, Eeced512-B5A6-11E8-9Efc-68B59976A384, Eed4Cb20-B5A6-11E8-9Efc-68B59976A384, Eedadf7E-B5A6-11E8-9Efc-68B59976A384, Eee12E74-B5A6-11E8-9Efc-68B59976A384, Eee7C87E-B5A6-11E8-9Efc-68B59976A384, Eeee2660-B5A6-11E8-9Efc-68B59976A384, Eef7663A-B5A6-11E8-9Efc-68B59976A384, Eefea85A-B5A6-11E8-9Efc-68B59976A384, Ef04C618-B5A6-11E8-9Efc-68B59976A384, Ef1E8A62-B5A6-11E8-9Efc-68B59976A384, Ef24Bbd0-B5A6-11E8-9Efc-68B59976A384, Ef2Ad826-B5A6-11E8-9Efc-68B59976A384, Ef30D4B0-B5A6-11E8-9Efc-68B59976A384, Ef3Fe72A-B5A6-11E8-9Efc-68B59976A384, Ef46105A-B5A6-11E8-9Efc-68B59976A384, Ef4C7B52-B5A6-11E8-9Efc-68B59976A384, Ef703Fd8-B5A6-11E8-9Efc-68B59976A384, Ef764356-B5A6-11E8-9Efc-68B59976A384, Ef89B832-B5A6-11E8-9Efc-68B59976A384, Ef942A06-B5A6-11E8-9Efc-68B59976A384, Ef9Eba34-B5A6-11E8-9Efc-68B59976A384, Efa444D6-B5A6-11E8-9Efc-68B59976A384, Efa91B82-B5A6-11E8-9Efc-68B59976A384, Efaeaec6-B5A6-11E8-9Efc-68B59976A384, Efc13Ea6-B5A6-11E8-9Efc-68B59976A384, Efe65754-B5A6-11E8-9Efc-68B59976A384, F01B9838-B5A6-11E8-9Efc-68B59976A384, F027766C-B5A6-11E8-9Efc-68B59976A384, F031Def4-B5A6-11E8-9Efc-68B59976A384, F04855E4-B5A6-11E8-9Efc-68B59976A384, F0629Aee-B5A6-11E8-9Efc-68B59976A384, F06D826A-B5A6-11E8-9Efc-68B59976A384, F07934A2-B5A6-11E8-9Efc-68B59976A384, F083A63A-B5A6-11E8-9Efc-68B59976A384, F08F6Ae2-B5A6-11E8-9Efc-68B59976A384, F099A6A6-B5A6-11E8-9Efc-68B59976A384, F0A5C68E-B5A6-11E8-9Efc-68B59976A384, F0B08C4A-B5A6-11E8-9Efc-68B59976A384, F0Baffc2-B5A6-11E8-9Efc-68B59976A384, F0C76F3C-B5A6-11E8-9Efc-68B59976A384, F0D4E266-B5A6-11E8-9Efc-68B59976A384, F0D985F0-B5A6-11E8-9Efc-68B59976A384, F0E139Bc-B5A6-11E8-9Efc-68B59976A384, F0Eb69E6-B5A6-11E8-9Efc-68B59976A384, F0F772Ea-B5A6-11E8-9Efc-68B59976A384, F10215Ec-B5A6-11E8-9Efc-68B59976A384] |
| ERP107948 |
| DEEP data release for IHEC/EpiRR 2018 data freeze. [Fibroblast, Hepatocyte, Liver, White Adipocyte] |
| ERP107409 |
| Defective germline reprogramming rewires the spermatogonial transcriptome [Undifferentiated Spermatogonia] |
| ERP022077 |
| A MILI independent piRNA biogenesis pathway residually loads MIWI2 empowering partial germline reprogramming activity. [Undifferentiated Spermatogonia] |
| ERP022031 |
| Epigenetic regulation and transcriptional repression by Tet1 in the early post-implantation mouse embryo: WG Bisulfite sequencing |
| ERP016240 |
| Genome-wide DNA methylation landscape defines specialization of regulatory T cells in tissues [Fat_Treg_R1, LN_Tconv_R2, LN_Tconv_R3, LN_Treg_R2, LN_Treg_R3, Liver_Treg_R1, Skin_Treg_R1, Skin_Treg_R2, Skin_Treg_R3] |
| ERP015660 |
| Quantifying epigenotype variations between mouse B and CD4+ T lymphocytes [CD4-positive, Alpha-Beta T Cell, Mature B Cell] |
| ERP012781 |
| Mice deficient of Myc super-enhancer region reveal a differential control mechanism between normal and pathological growth [Null_Fib-Bis-1, Null_Fib-Bis-2, WT_Fib-Bisseq-1, WT_Fib-Bisseq-2] |
| ERP010942 |
| We present the first genome-scale analysis of the effect of CpG methylation on DNA-binding of TFs. [Embryonic Cell, Embryonic Cell Deficient In Tet1, Tet2 And Tet3, GP5D Cell, LHSAR Cell, LHSAR Cell With HOXB13 Transduced, LoVo Cell, VCap Cell] |
| ERP008742 |
| Germ_cell_methylation_dynamics [056202C0-C771-11E6-Bf9C-68B59976A384, 056B78A0-C771-11E6-Bf9C-68B59976A384, 05727D80-C771-11E6-Bf9C-68B59976A384, 0Ec6Eaf0-5Fb7-11E6-B4F3-68B59976A384, 0Ee5Bd90-5Fb7-11E6-B4F3-68B59976A384, 11____EB2_B_-sc-2176524, 12____EB2_BS_-sc-2176525, 25Ab5C60-5Fb7-11E6-9477-68B599768938, 2Fe8D220-5Fb7-11E6-B4F6-68B59976A384, 2Ff491F0-5Fb7-11E6-B4F7-68B59976A384, 2Ffde0C0-5Fb7-11E6-B4F7-68B59976A384, 3F12Cf30-5Fb7-11E6-9477-68B599768938, 3F2015A0-5Fb7-11E6-9477-68B599768938, 47Ad1C40-5Fb7-11E6-B4F7-68B59976A384, 6Fc872F0-1B75-11E6-B065-68B59976A384, 6Ffc7B40-1B75-11E6-B065-68B59976A384, 83494700-1B75-11E6-B769-68B599768938, 835Db960-1B75-11E6-B769-68B599768938, 9____EB1_BS_-sc-2176522, A3_mPGCLC1-sc-2383193, C3_mPGCLC2-sc-2383195, D2_mPGCLC1-sc-2383188, D3_mPGCLC2-sc-2383196, Df89Bf70-C770-11E6-Bf9C-68B59976A384, Dfc31Ef0-C770-11E6-Bf9C-68B59976A384, Dfca9900-C770-11E6-Bf9C-68B59976A384, E3_mPGCLC2-sc-2383197, F1_hPGCLC1-sc-2383182, F28250B0-C770-11E6-83A1-68B599768938, F2895590-C770-11E6-83A1-68B599768938, F2978660-C770-11E6-83A1-68B599768938, F2_mPGCLC1-sc-2383190, F3_mPGCLC2-sc-2383198, G2_mPGCLC1-sc-2383191, G3_mPGCLC2-sc-2383199, H3_mPGCLC2-sc-2383200, PBAT20150318_S1-sc-2268397, PBAT20150318_S2-sc-2268398, PBAT20150318_S22-sc-2268418, PBAT20150318_S5-sc-2268401, PBAT20150318_S6-sc-2268402, hES1-sc-2351342, hES2-sc-2351343, hES3-sc-2351344, hKSR2-sc-2351346, hKSR3-sc-2351347] |
| ERP005247 |
| DNA methylation is required for the control of stem cell differentiation in the small intestine [Differentiated Intestinal Epithelium, Intestinal Stem Cell (LGR5 Positive)] |
| ERP004116 |
| Whole genome bisulfite sequencing of samples reprogramming to iPSC [1iPSC, 2MEF, 2iPSC, D11H, D16H, D16L, D18H, D21L, D21L0, D2H, D5H, D8H, ESC] |
| ERP003907 |
| Methylome_and_Hydroxymethylome_of_iPSC [2769STDY6182410-sc-2382182, 2769STDY6182411-sc-2382183, BSeq_MEF1-sc-1861756, BSeq_MEF2-sc-1861757, BSeq_MEF3-sc-1861758, BSeq_P29_iPSC44-sc-2014730, BSeq_P29_iPSC45-sc-2014731, BSeq_P29_iPSC66-sc-2014732, BSeq_P29_iPSC67-sc-2014733, BSeq_P29_iPSC72-sc-2014734, BSeq_P29_iPSC73-sc-2014735, BSeq_P8_iPSC67-sc-1861783, BSeq_P8_iPSC73-sc-1861785, BSeq_TMBD1-sc-1861759, BSeq_TMBD2-sc-1861760, BSeq_TMBD3-sc-1861761, BSeq_T_S_Exp10-sc-1861768, BSeq_T_S_Exp10-sc-1861769, BSeq_T_S_Exp11-sc-1861770, BSeq_T_S_Exp11-sc-1861771, BSeq_T_S_Exp16-sc-1861772, BSeq_T_S_Exp16-sc-1861773, TMBD10_BS-sc-2013-09-18T12:28:21Z-1692906, TMBD10_oxBS-sc-2013-09-18T12:28:31Z-1692907, iPSC19_BS-sc-2013-09-18T12:30:10Z-1692914, iPSC19_oxBS-sc-2013-09-18T12:31:26Z-1692918, iPSC20_BS-sc-2013-09-18T12:31:06Z-1692915, iPSC20_oxBS-sc-2013-09-18T12:30:31Z-1692919, iPSC27_BS-sc-2013-09-18T12:28:40Z-1692908, iPSC27_oxBS-sc-2013-09-18T12:29:46Z-1692911, iPSC28_BS-sc-2013-09-18T12:30:17Z-1692909, iPSC28_oxBS-sc-2013-09-18T12:29:53Z-1692912, iPSC29_BS-sc-2013-09-18T12:30:24Z-1692910, iPSC29_oxBS-sc-2013-09-18T12:30:03Z-1692913, iPSC37_BS-sc-2013-09-18T12:31:14Z-1692916, iPSC37_oxBS-sc-2013-09-18T12:30:37Z-1692920, iPSC38_BS-sc-2013-09-18T12:31:20Z-1692917, iPSC38_oxBS-sc-2013-09-18T12:30:43Z-1692921, oxBSeq_MEF1-sc-1861762, oxBSeq_MEF2-sc-1861763, oxBSeq_MEF3-sc-1861764, oxBSeq_P29_iPSC44-sc-2014736, oxBSeq_P29_iPSC45-sc-2014737, oxBSeq_P29_iPSC66-sc-2014738, oxBSeq_P29_iPSC67-sc-2014739, oxBSeq_P29_iPSC72-sc-2014740, oxBSeq_P29_iPSC73-sc-2014741, oxBSeq_TMBD1-sc-1861765, oxBSeq_TMBD2-sc-1861766, oxBSeq_TMBD3-sc-1861767, oxBSeq_T_S_Exp10-sc-1861774, oxBSeq_T_S_Exp10-sc-1861775, oxBSeq_T_S_Exp11-sc-1861776, oxBSeq_T_S_Exp11-sc-1861777, oxBSeq_T_S_Exp16-sc-1861778, oxBSeq_T_S_Exp16-sc-1861779, pMEFAIDKO_BS-sc-2013-09-18T12:31:41Z-1692923, pMEFAIDKO_oxBS-sc-2013-09-18T12:31:54Z-1692925, pMEFWt_BS-sc-2013-09-18T12:31:34Z-1692922, pMEFWt_oxBS-sc-2013-09-18T12:31:48Z-1692924] |
| ERP003744 |
| DNMT3_KO_BS_seq [EPC, Epiblast] |
| ERP001953 |
| The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells [Epiblast, J1 ES Cell, Primordial Germ Cell] |
| ERP001632 |
| B_Cell_Methylome [B Cells] |
| ERP001204 |
| DNA_methylation_reprogramming_in_PGCs [Embryonic Stem Cells, Epiblast Cells, Primordial Germ Cells] |
| DRP011537 |
| Tracking hematopoietic stem cell aging reveals its heterogeneous composition [Bone Marrow] |
| DRP011267 |
| whole genome bisulfite sequencing of colon and colon-derived organoids [Colon, Colon-Derived Organoid] |
| DRP010881 |
| Role of Tet3 in DNA demethylation in mouse SCNT embryos [SCNT Embryo] |
| DRP010625 |
| The identification of differentially methylated genes between hepatocytes and skeletal muscle of wild-type mice [Hepatocyte_01, Hepatocyte_02, Hepatocyte_03, Skeletal_Muscle_01, Skeletal_Muscle_02, Skeletal_Muscle_03] |
| DRP008539 |
| Investigation of the effects of sperm DNA methylation disturbance by testicular histone hyperacetylation on the next generation in mouse [Sperm] |
| DRP008439 |
| The DNMT3A ADD domain recognizing histone H3K4me0 is essential for processive DNA methylation and maternal imprinting in mouse oocytes [Embryo E10.5, Oocyte, Parthenogenesis Blastocyst] |
| DRP008292 |
| Whole genome bisulfite sequence of tissue and organoid [JB_colon_2, JB_colon_3, JB_colon_O2_Or, JB_colon_O3_Or] |
| DRP008086 |
| DNA methylation analysis of oocytes in a PCOS mouse model [Oocyte] |
| DRP006395 |
| The role of DNMT3B in inflammation-related hepatocarcinogenesis [Dnmt3bKO_NoTAA_1_WGBS, Dnmt3bWT_NoTAA_1_WGBS] |
| DRP004308 |
| MIWI2 targets RNAs transcribed from piRNA-dependently methylated regions in mouse gonocytes [Gonocyte] |
| DRP004153 |
| Mouse blactocyst methylome [Blastocyst, Parthenogenetic Blastocyst] |
| DRP003670 |
| Methylome of expanded mouse primordial germ cell-like cells [BVSC] |
| DRP003544 |
| Mouse NS/PCs DNA methylome (PBAT) [Astrocyte, Embryonic Stem Cell, Neural Stem/Progenitor Cell, Neuron, Oligodendrocyte] |
| DRP003407 |
| Software updates in the Illumina HiSeq platform affect whole-genome bisulfite sequencing [EpiLC, IMR-90, Spermatogonia] |
| DRP003273 |
| Methylome and transcriptome dynamics during mouse germ cell specification/differentiation in vitro |
| DRP002386 |
| Methylome and gene expression of neonatal prospermatogonia and early postnatal undifferentiated and differentiating spermatogonia [Testes] |
| DRP000638 |
| Mouse PGC DNA methylome (PBAT) [E10.5fPGC, E10.5mPGC, E13.5fPGC, E13.5mPGC, E16.5fPGC, E16.5mPGC] |
| DRP000598 |
| Mouse oocyte methylome [Dnmt1-deficient GV Oocyte, Dnmt3L-deficient GV Oocyte, Dnmt3a-deficient GV Oocyte, Dnmt3b-deficient GV Oocyte, Wild-Type GV Oocyte, Wild-Type NG Oocyte] |
| DRP000505 |
| Mouse DNA methylome (MethylC-seq) [Blastocyst, Embryonic Stem (ES) Cell, Sperm] |
| Common |
| Common methbase tracks for the mm39 assembly |
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| Base Position |
| Chromosome position in bases. (Clicks here zoom in 3x) |
| Assembly |
| Assembly from Fragments |
| Gap |
| Gap Locations |
| GC Percent |
| GC Percent in 5-Base Windows |
| GRC Incident |
| GRC Incident Database |
| INSDC |
| Accession at INSDC - International Nucleotide Sequence Database Collaboration |
| Restr Enzymes |
| Restriction Enzymes from REBASE |
| Short Match |
| Perfect Matches to Short Sequence () |
| Tandem Dups |
| Paired identical sequences |
| UCSC liftOver mm10 |
| UCSC liftOver alignments to mm10 |
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| updated
GENCODE VM36 |
| GENCODE VM36 |
| NCBI RefSeq |
| RefSeq genes from NCBI |
| updated
GENCODE Versions |
| Container of all new and previous GENCODE releases |
| All GENCODE VM26 |
| All GENCODE annotations from VM26 (Ensembl 103) |
| All GENCODE VM27 |
| All GENCODE annotations from VM27 (Ensembl 104) |
| All GENCODE VM28 |
| All GENCODE annotations from VM28 (Ensembl 105) |
| All GENCODE VM29 |
| All GENCODE annotations from VM29 (Ensembl 106) |
| All GENCODE VM30 |
| All GENCODE annotations from VM30 (Ensembl 107) |
| All GENCODE VM31 |
| All GENCODE annotations from VM31 (Ensembl 108) |
| All GENCODE VM32 |
| All GENCODE annotations from VM32 (Ensembl 109) |
| All GENCODE VM33 |
| All GENCODE annotations from VM33 (Ensembl 110) |
| All GENCODE VM34 |
| All GENCODE annotations from VM34 (Ensembl 111) |
| All GENCODE VM35 |
| All GENCODE annotations from VM35 (Ensembl 112) |
| new
All GENCODE VM36 |
| All GENCODE annotations from VM36 (Ensembl 113) |
| AUGUSTUS |
| AUGUSTUS ab initio gene predictions v3.1 |
| CRISPR Targets |
| CRISPR/Cas9 -NGG Targets, whole genome |
| GENCODE Archive |
| GENCODE Archive |
| GENCODE VM35 |
| GENCODE VM35 |
| GENCODE VM33 |
| GENCODE VM33 |
| GENCODE VM32 |
| GENCODE VM32 |
| GENCODE VM30 |
| GENCODE VM30 |
| GENCODE VM27 |
| GENCODE VM27 |
| Genscan Genes |
| Genscan Gene Predictions |
| Other RefSeq |
| Non-Mouse RefSeq Genes |
| Pfam in UCSC Gene |
| Pfam Domains in UCSC Genes |
| TOGA vs. hg38 |
| TOGA annotations using human/hg38 as reference |
| UCSC Alt Events |
| Alternative Splicing, Alternative Promoter and Similar Events in UCSC Genes |
| UniProt |
| UniProt SwissProt/TrEMBL Protein Annotations |
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| RefSeq mRNAs |
| RefSeq mRNAs mapped to this assembly |
| Mouse mRNAs |
| Mouse mRNAs from GenBank |
| Mouse ESTs |
| Mouse ESTs Including Unspliced |
| Other mRNAs |
| Non-Mouse mRNAs from GenBank |
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| CpG Islands |
| CpG Islands (Islands < 300 Bases are Light Green) |
| Unmasked CpG |
| CpG Islands on All Sequence (Islands < 300 Bases are Light Green) |
| CpG Islands |
| CpG Islands (Islands < 300 Bases are Light Green) |
| JASPAR Transcription Factors |
| JASPAR Transcription Factor Binding Site Database |
| ReMap ChIP-seq |
| ReMap Atlas of Regulatory Regions |
| VISTA Enhancers |
| VISTA Enhancers |
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| Conservation |
| Vertebrate Multiz Alignment & Conservation (35 Species) |
| Chain/Net |
| Chain and Net Alignments |
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| RepeatMasker |
| Repeating Elements by RepeatMasker |
| EVA SNP |
| Short Genetic Variants from European Variant Archive |
| Interrupted Rpts |
| Fragments of Interrupted Repeats Joined by RepeatMasker ID |
| Microsatellite |
| Microsatellites - Di-nucleotide and Tri-nucleotide Repeats |
| Simple Repeats |
| Simple Tandem Repeats by TRF |
| WM + SDust |
| Genomic Intervals Masked by WindowMasker + SDust |
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