UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to CTNNB1

CTNNB1 — TRRAP

Pathways - manually collected, often from reviews:

BioCarta multi-step regulation of transcription by pitx2: Tip60/TRRAP complex (HTATIP-TRRAP) → beta-catenin (CTNNB1) (modification, collaborate)
NCI Pathway Database Regulation of nuclear beta catenin signaling and target gene transcription: TCF4/beta catenin complex (TCF7L2-CTNNB1) → TRRAP (TRRAP) (modification, collaborate) Finkbeiner et al., Cell cycle (Georgetown, Tex.) 2008
Evidence: physical interaction
NCI Pathway Database Regulation of nuclear beta catenin signaling and target gene transcription: TCF4/beta catenin complex (TCF7L2-CTNNB1) → TCF4/beta catenin/TRRAP/SCF complex (TCF7L2-CTNNB1-TRRAP-BTRC-CUL1-SKP1) (modification, collaborate)
Finkbeiner et al., Cell cycle (Georgetown, Tex.) 2008
Evidence: physical interaction
NCI Pathway Database Regulation of nuclear beta catenin signaling and target gene transcription: TRRAP (TRRAP) → TCF4/beta catenin/TRRAP/SCF complex (TCF7L2-CTNNB1-TRRAP-BTRC-CUL1-SKP1) (modification, collaborate)
Finkbeiner et al., Cell cycle (Georgetown, Tex.) 2008
Evidence: physical interaction
NCI Pathway Database Regulation of nuclear beta catenin signaling and target gene transcription: SCF complex (BTRC-SKP1-CUL1) → TCF4/beta catenin/TRRAP/SCF complex (TCF7L2-CTNNB1-TRRAP-BTRC-CUL1-SKP1) (modification, collaborate)
Finkbeiner et al., Cell cycle (Georgetown, Tex.) 2008
Evidence: physical interaction
Reactome Reaction: TRRAP → CTNNB1 (indirect_complex) Bauer et al., EMBO J 2000, Feng et al., Cancer Res 2003, Kim et al., Nature 2005, Sierra et al., Genes Dev 2006, Bauer et al., Proc Natl Acad Sci U S A 1998
Reactome Reaction: TRRAP → CTNNB1 (reaction) Bauer et al., EMBO J 2000, Feng et al., Cancer Res 2003, Kim et al., Nature 2005, Sierra et al., Genes Dev 2006, Bauer et al., Proc Natl Acad Sci U S A 1998

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Biogrid Interaction: CTNNB1 — TRRAP (physical association, affinity chromatography technology) Sustmann et al., Mol Cell Biol 2008
IRef Biogrid Interaction: CTNNB1 — TRRAP (physical association, affinity chromatography technology) Sierra et al., Genes Dev 2006
IRef Biogrid Interaction: CTNNB1 — TRRAP (direct interaction, pull down) Sierra et al., Genes Dev 2006
IRef Biogrid Interaction: CTNNB1 — TRRAP (physical association, affinity chromatography technology) Gomes et al., Genes Dev 2006
Gene Ontology Complexes transcription factor complex: transcription factor complex complex (ATF7IP-GSC-GCM1-MAFB-NKX2-1-NKX2-5-RARG-KLF4-FOXF1-FOXF2-FOXE3-LDB1-ZFHX3-GATA6-SNAI3-FOXH1-KAT5-AHR-EYA3-NFATC2-CRX-MED27-HES6-SKI-XRCC6-ARNTL-SUB1-JUN-SOX17-SCX-DMBX1-TCF4-TCF7-PDLIM1-TFEB-LBX1-TRRAP-NAA16-EPAS1-MGA-PTF1A-HOXD12-MEF2B-TFDP3-TFDP1-HDAC2-YY1-SMAD9-CLOCK-ONECUT3-SMAD5-SMAD6-SMAD7-SMAD1-SMAD2-PRKDC-RCOR2-NHLH2-REL-TBX5-ARNTL2-BSX-HOXA10-HOXB13-MED23-PUS1-TAL1-RBL1-RBL2-MINA-HMGA1-BARX2-LEF1-EP300-PMF1-ARID5A-WWTR1-LMO2-LMO4-TP73-ABT1-CDK2-DKFZp686M216-CREG1-CTNNB1-SOX9-HAND2-SOX2-TEAD2-MYOG-TEAD4-CEBPA-GFI1B-MYOD1-ALX1-NPAS4-TFAP2D-FIGLA-ALX4-ETS1-PROP1-ASCL3-HCLS1-MSX1-MSX2-SRA1-AJUBA-MTA2-SIN3A-POU3F2-POU3F1-BEX1-MLXIPL-NR2E3-PBX2-ANKRD1-E2F6-E2F5-E2F4-E2F3-E2F2-E2F1-E2F8-CREBBP-ATF5-ATF4-POU2F3) Kaspar et al., J Biol Chem 1999, Wang et al., J Biol Chem 1999, Nagpal et al., J Biol Chem 1999, Blixt et al., Genes Dev 2000, Carlberg et al., Mol Cell Biol Res Commun 2000, Bae et al., Development 2000, Cairo et al., Hum Mol Genet 2001, Tutter et al., Genes Dev 2001, Willis et al., J Biol Chem 2002, Bayne et al., Mol Hum Reprod 2004, Schubert et al., J Biol Chem 2004, Han et al., J Mol Biol 2005, Rodriguez et al., EMBO J 2005, Han et al., Nucleic Acids Res 2005, Zhang et al., Mol Cell Biol 2007, Wong et al., Cell 2009, Stevens et al., Immunology 2009, Stefanovic et al., J Cell Biol 2009, Skokowa et al., Nat Med 2012, Ge et al., Cell 1994, Durocher et al., EMBO J 1997, Hogenesch et al., Proc Natl Acad Sci U S A 1998, Hellqvist et al., J Biol Chem 1998, Ryu et al., Nature 1999
IRef Intact Interaction: Complex of 248 proteins (association, pull down) von Eyss et al., EMBO J 2012