Description
Nextstrain.org displays
data about mutations that occur in the current 2019/2020 outbreak.
Nextstrain has a powerful user interface for viewing the evolutionary tree
that it infers from the patterns of mutations in sequences worldwide, but
does not offer a detailed plot of mutations along the genome, so we have processed
their genome annotations into genome browser tracks.
Use this track in conjunction with the track
Nextstrain Mutations (protein-coding mutations use gene names from this track).
Methods
Nextstrain downloads SARS-CoV-2 genomes from
GISAID
as they are submitted by labs worldwide.
The sequences are processed by an
automated pipeline
and annotations are written to a data file
that UCSC downloads and extracts annotations for display.
Data Access
You can download the bigBed file underlying this track (nextstrainGene) from our
Download Server. The data can be explored interactively with
the Table Browser
or the Data Integrator. The data can be
accessed from scripts through our API.
Credits
Thanks to
nextstrain.org for
sharing its analysis of genomes collected by
GISAID,
and to researchers worldwide for sharing their SARS-CoV-2 genome sequences.
References
Hadfield J, Megill C, Bell SM, Huddleston J, Potter B, Callender C, Sagulenko P, Bedford T, Neher
RA.
Nextstrain: real-time tracking of pathogen evolution.
Bioinformatics. 2018 Dec 1;34(23):4121-4123.
PMID: 29790939; PMC: PMC6247931
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