IEDB Prediction IEDB Pred Macaque I Track Settings
 
IEDB Epitope Predictions, Macaque T-Cell Class I

Track collection: Immune Epitope Database and Analysis Resource (IEDB) HLA binding predictions

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 A*01  IEDB Predicted binding Macaque HLA T-Cell Class I A*01   Data format 
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 A*02  IEDB Predicted binding Macaque HLA T-Cell Class I A*02   Data format 
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 A*07  IEDB Predicted binding Macaque HLA T-Cell Class I A*07   Data format 
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 A*11  IEDB Predicted binding Macaque HLA T-Cell Class I A*11   Data format 
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 A1*02201  IEDB Predicted binding Macaque HLA T-Cell Class I A1*02201   Data format 
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 A1*02601  IEDB Predicted binding Macaque HLA T-Cell Class I A1*02601   Data format 
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 A2*0102  IEDB Predicted binding Macaque HLA T-Cell Class I A2*0102   Data format 
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 A7*0103  IEDB Predicted binding Macaque HLA T-Cell Class I A7*0103   Data format 
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 B*00101  IEDB Predicted binding Macaque HLA T-Cell Class I B*00101   Data format 
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 B*00301  IEDB Predicted binding Macaque HLA T-Cell Class I B*00301   Data format 
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 B*01  IEDB Predicted binding Macaque HLA T-Cell Class I B*01   Data format 
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 B*01001  IEDB Predicted binding Macaque HLA T-Cell Class I B*01001   Data format 
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 B*03901  IEDB Predicted binding Macaque HLA T-Cell Class I B*03901   Data format 
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 B*06601  IEDB Predicted binding Macaque HLA T-Cell Class I B*06601   Data format 
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 B*08  IEDB Predicted binding Macaque HLA T-Cell Class I B*08   Data format 
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 B*08301  IEDB Predicted binding Macaque HLA T-Cell Class I B*08301   Data format 
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 B*08701  IEDB Predicted binding Macaque HLA T-Cell Class I B*08701   Data format 
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 B*09001  IEDB Predicted binding Macaque HLA T-Cell Class I B*09001   Data format 
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 B*17  IEDB Predicted binding Macaque HLA T-Cell Class I B*17   Data format 
    
Assembly: Ebola virus Sierra Leone 2014 (G3683/KM034562.1/eboVir3)

Description

This track shows peptides that are predicted to be displayed by macaque class I MHCs.

Display Conventions and Configuration

Peptides are shaded by IC50 values and split into subtracks by HLA-alleles.

Methods

For human epitope prediction, binding affinity for all possible 9-mer peptides from each protein sequence to a set of 27 HLA alleles that are most frequent in the global population, using the SMM method available in the IEDB MHC class I binding prediction tool. All peptides with predicted binding affinity (expressed as IC50 nM) below previously optimized allele-specific thresholds were selected as predicted binders. In the case of rhesus macaque class I T cell epitope prediction, the binding affinity of all 9-mer peptides was predicted for a total of 19 alleles (7 Indian and 12 Chinese rhesus macaques) that are most frequent in these species. The binding affinity predictions utilized the "IEDB recommended" method from the IEDB MHC class I binding prediction tool. Peptides with the IEDB consensus percentile rank <= 1.0 were selected. Lower values for either IC50 or percentile rank indicate stronger binding.