UCSC S. cerevisiae Gene Sorter

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UCSC S. cerevisiae Gene Sorter

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#	Name	SGD ORF	Module	BLASTP E-Value	Genome Position	Description
1	MF(ALPHA)1	YPL187W	523	n/a	chrXVI 193,896	Mating pheromone alpha-factor, made by alpha cells interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating also encoded by MF(ALPHA)2, although MF(ALPHA)1 produces most alpha-factor
2	MATALPHA1	YCR040W	523	n/a	chrIII 200,705	Transcriptional co-activator involved in regulation of mating-type-specific gene expression targets the transcription factor Mcm1p to the promoters of alpha-specific genes one of two genes encoded by the MATalpha mating type cassette
3	HMLALPHA1	YCL066W	523	n/a	chrIII 13,545	Silenced copy of ALPHA1 at HML, encoding a transcriptional coactivator involved in the regulation of mating-type alpha-specific gene expression
4	ARG80	YMR042W	523	n/a	chrXIII 352,869	Transcription factor involved in regulation of arginine-responsive genes acts with Arg81p and Arg82p
5	TIR1	YER011W	523	n/a	chrV 175,630	Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins expression is downregulated at acidic pH and induced by cold shock and anaerobiosis abundance is increased in cells cultured without shaking
6	MET8	YBR213W	523	n/a	chrII 650,780	Bifunctional dehydrogenase and ferrochelatase, involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase required for sulfate assimilation and methionine biosynthesis
7	PDC6	YGR087C	523	n/a	chrVII 652,135	Minor isoform of pyruvate decarboxylase, decarboxylates pyruvate to acetaldehyde, involved in amino acid catabolism transcription is glucose- and ethanol-dependent, and is strongly induced during sulfur limitation
8	SCM4	YGR049W	523	n/a	chrVII 591,595	Potential regulatory effector of CDC4 function, suppresses a temperature-sensitive allele of CDC4, tripartite protein structure in which a charged region separates two uncharged domains, not essential for mitosis or meiosis
9	TIR2	YOR010C	523	n/a	chrXV 346,572	Putative cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins transcription is induced by cold shock and anaerobiosis
10	HES1	YOR237W	523	n/a	chrXV 782,646	Protein implicated in the regulation of ergosterol biosynthesis one of a seven member gene family with a common essential function and non-essential unique functions similar to human oxysterol binding protein (OSBP)
11	APT2	YDR441C	523	n/a	chrIV 1,344,789	Apparent pseudogene, not transcribed or translated under normal conditions encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity
12	PCH2	YBR186W	523	n/a	chrII 601,456	Nucleolar component of the pachytene checkpoint, which prevents chromosome segregation when recombination and chromosome synapsis are defective also represses meiotic interhomolog recombination in the rDNA
13	FIG1	YBR040W	523	n/a	chrII 317,416	Integral membrane protein required for efficient mating may participate in or regulate the low affinity Ca2+ influx system, which affects intracellular signaling and cell-cell fusion during mating
14	YER187W	YER187W	523	n/a	chrV 566,442	Putative protein of unknown function induced in respiratory-deficient cells
15	QDR2	YIL121W	523	n/a	chrIX 133,058	Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin may have a role in potassium uptake
16	SYG1	YIL047C	523	n/a	chrIX 266,469	Plasma membrane protein of unknown function truncation and overexpression suppresses lethality of G-alpha protein deficiency
17	TIR3	YIL011W	523	n/a	chrIX 334,131	Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins expressed under anaerobic conditions and required for anaerobic growth
18	GAT4	YIR013C	523	n/a	chrIX 380,201	Protein containing GATA family zinc finger motifs
19	OPT1	YJL212C	523	n/a	chrX 35,049	Proton-coupled oligopeptide transporter of the plasma membrane also transports glutathione and phytochelatin member of the OPT family
20	STB1	YNL309W	523	n/a	chrXIV 53,293	Protein with a role in regulation of MBF-specific transcription at Start, phosphorylated by Cln-Cdc28p kinases in vitro unphosphorylated form binds Swi6p and binding is required for Stb1p function expression is cell-cycle regulated
21	RSC8	YFR037C	523	n/a	chrVI 228,349	Component of the RSC chromatin remodeling complex essential for viability and mitotic growth homolog of SWI/SNF subunit Swi3p, but unlike Swi3p, does not activate transcription of reporters
22	ALT2	YDR111C	523	n/a	chrIV 679,002	Putative alanine transaminase (glutamic pyruvic transaminase)
23	HOP2	YGL033W	523	n/a	chrVII 435,988	Meiosis-specific protein that localizes to chromosomes, preventing synapsis between nonhomologous chromosomes and ensuring synapsis between homologs complexes with Mnd1p to promote homolog pairing and meiotic double-strand break repair
24	POP6	YGR030C	523	n/a	chrVII 545,919	Subunit of both RNase MRP and nuclear RNase P RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs
25	PAP2	YOL115W	523	n/a	chrXV 102,352	Non-canonical poly(A) polymerase, involved in nuclear RNA degradation as a component of the TRAMP complex catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors overlapping but non-redundant functions with Trf5p
26	YNR063W	YNR063W	523	n/a	chrXIV 747,854	Putative zinc-cluster protein of unknown function
27	MAK10	YEL053C	523	n/a	chrV 55,001	Non-catalytic subunit of N-terminal acetyltransferase of the NatC type, required for replication of dsRNA virus expression is glucose-repressible
28	ECM23	YPL021W	523	n/a	chrXVI 511,382	Non-essential protein of unconfirmed function affects pre-rRNA processing, may act as a negative regulator of the transcription of genes involved in pseudohyphal growth homologous to Srd1p
29	YMR244W	YMR244W	523	n/a	chrXIII 757,783	Putative protein of unknown function
30	ECM11	YDR446W	523	n/a	chrIV 1,354,179	Non-essential protein apparently involved in meiosis, GFP fusion protein is present in discrete clusters in the nucleus throughout mitosis may be involved in maintaining chromatin structure
31	GAS2	YLR343W	523	n/a	chrXII 816,927	1,3-beta-glucanosyltransferase, involved with Gas4p in spore wall assembly has similarity to Gas1p
32	YDL129W	YDL129W	523	n/a	chrIV 231,461	Putative protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus YDL129W is not an essential gene
33	GAT3	YLR013W	523	n/a	chrXII 171,551	Protein containing GATA family zinc finger motifs
34	MUM3	YOR298W	523	0	chrXV 876,318	Protein of unknown function involved in the organization of the outer spore wall layers has similarity to the tafazzins superfamily of acyltransferases
35	TIR4	YOR009W	523	n/a	chrXV 345,066	Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins expressed under anaerobic conditions and required for anaerobic growth transcription is also induced by cold shock
36	ARP7	YPR034W	523	n/a	chrXVI 640,241	Component of both the SWI/SNF and RSC chromatin remodeling complexes actin-related protein involved in transcriptional regulation
37	HTZ1	YOL012C	523	n/a	chrXV 303,781	Histone variant H2AZ, exchanged for histone H2A in nucleosomes by the SWR1 complex involved in transcriptional regulation through prevention of the spread of silent heterochromatin