UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZK938.2	ZK938.2	0	chrII 9,837,617	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
2	F26D2.13	F26D2.13	n/a	chrV 16,435,139	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
3	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
4	clec-9	Y70C5C.2	n/a	chrV 16,705,835	C. elegans CLEC-9 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
5	F16D3.6	F16D3.6	n/a	chrI 8,376,505	contains similarity to Pfam domain PF06681 Protein of unknown function (DUF1182) contains similarity to Interpro domains IPR002091 (Aromatic amino acid permease), IPR010601 (Protein of unknown function DUF1182)
6	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
7	unc-42	F58E6.10	n/a	chrV 9,766,975	unc-42 encodes a paired-like homeodomain protein of the Q50 class; UNC-42 is required to specify the fate of ASH sensory neurons, AVA, AVD, and AVE interneurons, and a subset of motor neurons; unc-42 mutants fail to express cell-surface receptors required for differentiated neuronal function (sra-6, srb-6, glr-1, glr-5, and glr-6); UNC-42 is also required for AVKR and HSNL growth cones to follow the PVPR and PVQL pioneer axons, for axonal outgrowth in the backward command interneurons AVA, AVD, and AVE, and for inhibition of ectopic FMRFamide-positive and GABAergic axons; unc-42 mutants are defective in mechanosensation, backward motion, and regulation of egg-laying.
8	F28G4.4	F28G4.4	n/a	chrV 16,284,328	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domains IPR017853 (Glycoside hydrolase, catalytic core), IPR005069 (Protein of unknown function DUF271)
9	T24D8.6	T24D8.6	n/a	chrX 2,365,815
10	srt-71	C50H11.3	n/a	chrV 3,084,429	C. elegans SRT-71 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR002208 (SecY protein)
11	T15B7.14	T15B7.14	n/a	chrV 6,833,799
12	F53B3.5	F53B3.5	n/a	chrX 2,876,207	F53B3.5 encodes a claudin homolog that may regulate ion channels; F53B3.5 is distantly similar to mammalian voltage-dependent calcium channel gamma subunits that are known or suspected to prevent epilepsy in vivo (e.g., stargazin; MGI:1316660); F53B3.5 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
13	hhat-2	Y57G11C.17	n/a	chrIV 14,827,743	C. elegans HHAT-2 protein; contains similarity to Pfam domain PF03062 MBOAT family contains similarity to Interpro domain IPR004299 (Membrane bound O-acyl transferase, MBOAT)
14	dylt-2	D1009.5	n/a	chrX 8,939,705	dylt-2 encodes a small putative dynein light chain subunit orthologous to human CTEX1D1, LOC343521, and TCTE3; unlike its distant paralog DYLT-1, DYLT-2 does not obviously inhibit DHC-1 in vivo; DYTL-2 has no obvious function in mass RNAi assays.
15	hlh-26	C17C3.8	n/a	chrII 5,533,262	C. elegans HLH-26 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
16	C35E7.3	C35E7.3	n/a	chrI 10,837,920
17	sir-2.3	F46G10.3	n/a	chrX 13,332,774	C. elegans SIR-2.3 protein; contains similarity to Pfam domain PF02146 Sir2 family contains similarity to Interpro domain IPR003000 (NAD-dependent histone deacetylase, silent information regulator Sir2)
18	T10B5.4	T10B5.4	n/a	chrV 1,871,195	contains similarity to Pfam domain PF00583 Acetyltransferase (GNAT) family contains similarity to Interpro domains IPR000182 (GCN5-related N-acetyltransferase), IPR016181 (Acyl-CoA N-acyltransferase)
19	inx-6	C36H8.2	n/a	chrIV 12,748,113	inx-6 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; INX-6 is required for formation of pharyngeal gap junctions and thus for the electrical coupling and synchronous muscle contractions necessary for normal feeding behavior and postembryonic development; INX-6 may function redundantly with EAT-5, another C. elegans innexin; INX-6 expression is first detected in embryonic pharyngeal precursors and during later larval and adult stages, in pharyngeal corpus muscles and isthmus marginal cells, where INX-6 localizes to plaque-like structures in the plasma membrane.
20	pmk-1	B0218.3	n/a	chrIV 8,149,748	pmk-1 encodes a mitogen-activated protein kinase (MAPK), orthologous to human p38 MAPK (OMIM:600289), that is required for eliciting gonadal programmed cell death in response to Salmonella enterica infection; PMK-1 lies upstream of CED-9, a negative regulator of apoptosis, in the programmed cell death pathway.
21	K02E10.7	K02E10.7	n/a	chrX 2,504,770	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
22	dyf-8	C43C3.3	n/a	chrX 9,700,112	dyf-8 encodes a protein predicted to form a cell-surface ligand with a zona pellucida domain; DYF-8 is required for permeability of amphid and phasmid neurons to external dyes, chemotaxis to ammonium chloride, avoidance of high osmotic stimuli, male mating, and dauer formation.
23	B0365.7	B0365.7	n/a	chrV 13,144,616	contains similarity to Pfam domain PF08393 Dynein heavy chain, N-terminal region 2 contains similarity to Interpro domains IPR013602 (Dynein heavy chain, N-terminal region 2), IPR000215 (Protease inhibitor I4, serpin)
24	F55C9.11	F55C9.11	n/a	chrV 19,307,376	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
25	fkh-8	F40H3.4	n/a	chrII 6,190,440	fkh-8 encodes one of 15 C. elegans forkhead transcription factors; loss of fkh-8 activity via RNAi has been reported to result in either no defects or a weakly penetrant aldicarb resistance phenotype; an FKH-8 reporter fusion is expressed in nerve cells in the head and tail ganglia of both males and hermaphrodites with expression beginning in the later stages of embryogenesis and continuing through adulthood.
26	ugt-56	T04H1.8	n/a	chrV 12,260,070	C. elegans UGT-56 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
27	srb-9	F37C12.16	n/a	chrIII 7,174,868	C. elegans SRB-9 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR000344 (Nematode chemoreceptor, Sra)
28	srb-2	C27D6.9	n/a	chrII 5,168,699	C. elegans SRB-2 protein; contains similarity to Pfam domain PF02175 C.elegans integral membrane protein Srb contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
29	srd-15	C04E6.10	n/a	chrV 5,905,617	C. elegans SRD-15 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like)
30	C07E3.8	C07E3.8	n/a	chrII 10,352,798	contains similarity to Pfam domain PF06542 Protein of unknown function (DUF1114) contains similarity to Interpro domain IPR009497 (Protein of unknown function DUF1114)
31	C04A11.2	C04A11.2	n/a	chrX 13,667,311	contains similarity to Homo sapiens Putative protein TPRXL; ENSEMBL:ENSP00000322097
32	Y56A3A.28	Y56A3A.28	n/a	chrIII 11,966,536	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR007087 (Zinc finger, C2H2-type)
33	F58E1.10	F58E1.10	n/a	chrII 1,690,389
34	gcy-22	T03D8.5	n/a	chrV 20,818,085	gcy-22 is predicted to encode a guanylate cyclase.
35	E03H4.7	E03H4.7	n/a	chrI 12,422,814	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
36	F37C4.3	F37C4.3	n/a	chrIV 3,883,226	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
37	srx-97	F19B10.7	n/a	chrII 3,667,915	C. elegans SRX-97 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
38	osm-1	T27B1.1	n/a	chrX 16,546,188	osm-1 encodes a WD- and WAA-repeat containing protein that is the C. elegans ortholog of intraflagellar transport (IFT) complex B component IFT172; OSM-1 is a presumptive cargo molecule for kinesin-II, and OSM-1 is required, along with OSM-6, for the proper assembly of the middle segments of sensory cilia; osm-1 may act in a pathway with avr-14 to affect resistance to ivermectin-induced cessation of pumping, and mutants are defective in avoidance of solutions of high osmotic strength; an OSM-1::GFP fusion protein is expressed in amphid and phasmid chemosensory neurons where it undergoes both anterograde and retrograde intraflagellar transport.
39	F53A2.1	F53A2.1	n/a	chrIII 13,321,932	contains similarity to Pfam domain PF06542 Protein of unknown function (DUF1114) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR009497 (Protein of unknown function DUF1114), IPR009010 (Aspartate decarboxylase-like fold)
40	ZC190.6	ZC190.6	n/a	chrV 8,675,924
41	gpa-9	F56H9.4	n/a	chrV 12,648,055	gpa-9 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ASJ, PHB, PVQ, pharyngeal muscle, and the spermatheca.
42	F56C3.4	F56C3.4	n/a	chrX 1,360,874
43	srh-140	Y6E2A.6	n/a	chrV 15,723,067	C. elegans SRH-140 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000484 (Photosynthetic reaction centre, L and M subunits)
44	R52.4	R52.4	n/a	chrII 2,107,797
45	aat-3	F52H2.2	n/a	chrX 2,555,967	aat-3 encodes an amino acid transporter catalytic subunit; when co-expressed in Xenopus oocytes with the ATG-2 glycoprotein subunit, AAT-3 is able to facilitate amino acid uptake and exchange, showing a relatively high affinity for small and some large neutral amino acids; in addition, AAT-3 is able to covalently associate with ATG-2 or ATG-1 to form heterodimers in the Xenopus expression system; when co-expressed with ATG-2, AAT-3 localizes to the cell surface of oocytes, but when expressed alone, or with ATG-1, AAT-3 localizes intracellularly.
46	fbxb-101	Y63D3A.3	n/a	chrI 14,088,963	C. elegans FBXB-101 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
47	F41C3.6	F41C3.6	n/a	chrII 4,735,969
48	srbc-16	C45H4.1	n/a	chrV 2,182,614	C. elegans SRBC-16 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
49	R08C7.1	R08C7.1	n/a	chrIV 4,451,940
50	M28.1	M28.1	n/a	chrII 10,624,279	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)