UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	gcy-18	ZK896.8	0	chrIV 12,863,005	gcy-18 encodes a receptor-type guanylyl cyclase that, along with gcy-8 and gcy-23, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-18 functions redundantly with gcy-8 and gcy-23, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; in addition, microarray experiments indicate that gcy-18 expression is induced in daf-16(RNAi); daf-2(RNAi) double mutants and repressed in daf-2(RNAi) mutants, suggesting that GCY-18 activity may contribute to a shortened lifespan; consistent with this, loss of gcy-18 activity via RNAi does result in lifespan extension; GCY-18 is expressed exclusively in the AFD thermosensory neurons, where it localizes to sensory endings.
2	W02B8.3	W02B8.3	n/a	chrII 13,917,920	contains similarity to Pfam domain PF04870 Protein of unknown function, DUF644 contains similarity to Interpro domain IPR006954 (Protein of unknown function DUF644)
3	K11H12.4	K11H12.4	n/a	chrIV 674,988	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
4	H35B03.1	H35B03.1	n/a	chrIV 5,727,641
5	F02E11.2	F02E11.2	n/a	chrII 3,267,119
6	R05G6.1	R05G6.1	n/a	chrIV 7,539,920
7	F29A7.3	F29A7.3	n/a	chrII 2,753,579	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
8	srab-9	C36C5.6	n/a	chrV 3,140,609	C. elegans SRAB-9 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
9	btb-15	C08E3.2	n/a	chrII 1,611,924	C. elegans BTB-15 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
10	4R79.2	4R79.2	n/a	chrIV 17,481,819	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR006688 (ADP-ribosylation factor), IPR002041 (Ran GTPase), IPR013753 (Ras), IPR006687 (GTP-binding protein SAR1), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR001806 (Ras GTPase), IPR005225 (Small GTP-binding protein), IPR003579 (Ras small GTPase, Rab type)
11	rab-14	K09A9.2	n/a	chrX 15,605,871	rab-14 encodes a member of the Rab GTPase family.
12	C56A3.3	C56A3.3	n/a	chrV 13,533,300	C56A3.3 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that C56A3.3 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
13	C38C3.7	C38C3.7	n/a	chrV 1,502,860	contains similarity to Pfam domains PF01827 (FTH domain) (2), PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
14	C04E7.1	C04E7.1	n/a	chrX 359,435
15	gnrr-5	H22D07.1	n/a	chrV 4,452,877	C. elegans GNRR-5 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
16	C56E6.6	C56E6.6	n/a	chrII 6,542,233	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
17	F54C4.4	F54C4.4	n/a	chrIII 87,055
18	mif-3	F13G3.9	n/a	chrI 7,313,193	C. elegans MIF-3 protein; contains similarity to Pfam domain PF01187 Macrophage migration inhibitory factor (MIF) contains similarity to Interpro domains IPR014347 (Tautomerase), IPR001398 (Macrophage migration inhibitory factor)
19	C36E8.4	C36E8.4	n/a	chrIII 4,014,026	contains similarity to Pfam domain PF00018 SH3 domain contains similarity to Interpro domains IPR001060 (Cdc15/Fes/CIP4), IPR001452 (Src homology-3)
20	F57C12.2	F57C12.2	n/a	chrX 548,426	contains similarity to Pfam domain PF04670 Gtr1/RagA G protein conserved region contains similarity to Interpro domains IPR009053 (Prefoldin), IPR006762 (Gtr1/RagA G protein)
21	F16H6.6	F16H6.6	n/a	chrV 18,205,786	contains similarity to Anthyllis vulneraria subsp lapponica Maturase-like protein.; TR:Q8HUG8
22	C35A11.2	C35A11.2	n/a	chrV 5,387,617
23	Y37H9A.2	Y37H9A.2	n/a	chrI 13,780,578	contains similarity to Candida albicans Hyphally regulated protein precursor.; SW:HYR1_CANAL
24	CD4.5	CD4.5	n/a	chrV 5,590,729
25	F45C12.9	F45C12.9	n/a	chrII 1,709,067	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
26	Y51A2D.1	Y51A2D.1	n/a	chrV 18,510,717	contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
27	acy-3	C44F1.5	0.0006	chrIII 3,778,374	acy-3 encodes a predicted member of the adenylyl cyclase family with highest similarity to human adenylate cyclase type 5; expressed in the support cells of ciliated neurons, in the head and tail ganglia, in two pairs of neurons in the retrovesicular ganglia, and in the spermatheca.
28	F32D1.3	F32D1.3	n/a	chrV 4,355,654	contains similarity to Pfam domains PF07719 (Tetratricopeptide repeat) (3), PF08409 (Domain of unknown function (DUF1736)) , PF00515 (Tetratricopeptide repeat) (6)contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR013618 (Region of unknown function DUF1736), IPR008940 (Protein prenyltransferase), IPR001440 (Tetratricopeptide TPR-1), IPR013105 (Tetratricopeptide TPR2), IPR013026 (Tetratricopeptide region)
29	F55A4.7	F55A4.7	n/a	chrX 1,037,733	contains similarity to Pfam domain PF00402 Calponin family repeat contains similarity to Interpro domain IPR000557 (Calponin repeat)
30	sng-1	T08A9.3	n/a	chrX 7,328,590	sng-1 encodes the C. elegans synaptogyrin ortholog, a vertebrate integral membrane synaptic vesicle protein; loss-of-function mutations in sng-1 result in no obvious defects in synaptogenesis or neuronal activity, suggesting that SNG-1 is likely required for more subtle neuronal functions; SNG-1::GFP reporters are expressed throughout the nervous system in neurons in the dorsal and ventral nerve cords, as well as the anterior nerve ring; SNG-1 colocalizes with the synaptic vesicle component SNT-1.
31	srz-10	ZK1037.11	n/a	chrV 15,308,296	C. elegans SRZ-10 protein ;
32	clec-146	Y48E1B.9	n/a	chrII 13,592,126	C. elegans CLEC-146 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
33	F22G12.5	F22G12.5	n/a	chrI 13,172,567	contains similarity to Interpro domain IPR001765 (Carbonic anhydrase)
34	E01G4.1	E01G4.1	n/a	chrII 13,445,298	contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
35	M163.1	M163.1	n/a	chrX 14,503,087	contains similarity to Mus musculus Adapter-related protein complex 3 beta 1 subunit (Beta-adaptin 3A)s(AP-3 complex beta-3A subunit) (Beta-3A-adaptin).; SW:A3B1_MOUSE
36	C18H7.6	C18H7.6	n/a	chrIV 590,772	contains similarity to Interpro domain IPR000817 (Prion protein)
37	ins-24	ZC334.3	n/a	chrI 14,031,394	ins-24 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-24 is one of 38 insulin-like peptides in C. elegans, but as loss of INS-24 function via RNA-mediated interference does not result in any abnormalities, the precise role of INS-24 in C. elegans development is not yet clear.
38	srd-70	F48F5.4	n/a	chrV 20,450,660	C. elegans SRD-70 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
39	C16D6.1	C16D6.1	n/a	chrX 12,525,704	contains similarity to Interpro domain IPR000694 (Proline-rich region)
40	T27D1.3	T27D1.3	n/a	chrIII 3,684,552	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR008365 (Prostanoid receptor), IPR001991 (Sodium:dicarboxylate symporter), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B), IPR000276 (GPCR, rhodopsin-like)
41	F55C7.2	F55C7.2	n/a	chrI 4,005,729
42	Y57A10B.1	Y57A10B.1	n/a	chrII 12,362,805	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
43	F31F4.11	F31F4.11	n/a	chrV 663,441	contains similarity to Pfam domains PF00788 (Ras association (RalGDS/AF-6) domain) , PF02204 (Vacuolar sorting protein 9 (VPS9) domain) contains similarity to Interpro domains IPR013995 (Vacuolar sorting protein 9, subgroup), IPR003123 (Vacuolar sorting protein 9), IPR000159 (Ras-association)
44	str-143	C09H5.4	n/a	chrV 8,068,920	C. elegans STR-143 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	abt-3	F55G11.9	n/a	chrIV 12,953,691	abt-3 encodes a predicted ATP-binding cassette (ABC) transporter that is a member of the ABCA subfamily of transport proteins; ABT-3 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of abt-3 activity via RNAi results in no obvious defects, the precise role of abt-3 in C. elegans development and/or behavior is not yet known.
46	fbxa-129	F59A1.8	n/a	chrV 17,656,084	C. elegans FBXA-129 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
47	Y48E1C.3	Y48E1C.3	n/a	chrII 13,439,410	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
48	T28A11.13	T28A11.13	n/a	chrV 3,249,973	contains similarity to Interpro domains IPR011594 (Thioredoxin-like), IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR006662 (Thioredoxin-related)
49	Y17G7B.19	Y17G7B.19	n/a	chrII 12,110,327	contains similarity to Pfam domain PF01666 (DX module)
50	str-66	Y73C8C.5	n/a	chrV 3,103,680	C. elegans STR-66 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)