UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZK849.1	ZK849.1	0	chrI 14,184,199	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
2	clec-135	C16A11.8	n/a	chrII 4,257,930	C. elegans CLEC-135 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
3	T01H3.5	T01H3.5	n/a	chrII 7,880,026	T01H3.5 encodes an unfamiliar protein; T01H3.5 and T01H3.5 share an operon divergently transcribed from another operon containing vha-4.
4	sfa-1	Y116A8C.32	n/a	chrIV 17,107,555	Y116A8C.32 encodes an ortholog of splicing factor SF1, which enables 3' splice site recognition by binding U2AF65 and the intron branch site during splicing complex formation; Y116A8C.32 shares several domains with mammalian SF1 proteins (a U2AF65 binding domain, a hnRNP K homology domain, two RNA-binding zinc knuckles, and a proline-rich C-terminal domain), while also sharing a hydrophilic N-terminal domain (enriched for serine, arginine, lysine, and aspartate) with Drosophila but not mammalian SF1; Y116A8C.32's N-terminal domain resembles RS domains in other splicing proteins; Y116A8C.32 is required for embryonic viability, normally rapid growth, and proper body morphology.
5	ace-1	W09B12.1	n/a	chrX 16,370,244	ace-1 encodes a class A acetylcholinesterase that functions redundantly with ACE-2 with respect to total class A acetylcholinesterase activity, and that genetically interacts with ace-2 and ace-3; ace-1 is expressed in the body wall muscle, sphincter muscle, head neurons, a few pharyngeal muscle cells, and the diagonal and spicule muscles of the male.
6	W09G12.6	W09G12.6	n/a	chrIV 1,232,354	contains similarity to Interpro domain IPR000104 (Antifreeze protein, type I)
7	snf-7	ZK1010.9	n/a	chrIII 13,008,187	C. elegans SNF-7 protein; contains similarity to Pfam domain PF00209 Sodium:neurotransmitter symporter family contains similarity to Interpro domain IPR000175 (Sodium:neurotransmitter symporter)
8	K01A6.4	K01A6.4	n/a	chrIV 11,739,659	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR001419 (HMW glutenin)
9	AC7.3	AC7.3	n/a	chrIV 5,112,248
10	Y43F8C.15	Y43F8C.15	n/a	chrV 19,705,582
11	C16C8.17	C16C8.17	n/a	chrII 3,441,631	contains similarity to Pfam domain PF03436 Domain of unknown function (DUF281) contains similarity to Interpro domain IPR005098 (Protein of unknown function DUF281)
12	R13G10.4	R13G10.4	n/a	chrIII 3,827,770	R13G10.4 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C01H6.6, C33D12.2, C52D10.12, M02F4.3, and R04E5.2; by orthology with MAM3, R13G10.4 may participate in metal homoeostasis; R13G10.4, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; R13G10.4 is required for normal development in mass RNAi assays.
13	ZK1010.5	ZK1010.5	n/a	chrIII 12,985,882	contains similarity to Interpro domain IPR000694 (Proline-rich region)
14	K07F5.8	K07F5.8	n/a	chrIV 9,849,087	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
15	C46H11.6	C46H11.6	n/a	chrI 5,022,021	contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
16	ZC581.7	ZC581.7	n/a	chrI 6,661,388	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
17	C08G5.2	C08G5.2	n/a	chrII 740,228
18	clec-261	ZC15.6	n/a	chrV 20,287,601	C. elegans CLEC-261 protein; contains similarity to Interpro domains IPR000817 (Prion protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
19	ZK1290.11	ZK1290.11	n/a	chrII 7,561,190
20	Y24D9B.1	Y24D9B.1	n/a	chrIV 4,319,658	contains similarity to Interpro domain IPR001469 (ATPase, F1 complex, delta/epsilon subunit)
21	ncl-1	ZK112.2	n/a	chrIII 7,734,657	ncl-1 encodes a cytoplasmic B-box zinc finger protein that negatively regulates rRNA and 5S RNA transcription, nucleolus size, and body size; NCL-1 is orthologous to Drosophila BRAIN TUMOR (BRAT), and ncl-1 mutants can be rescued by brat transgenes; NCL-1 is required for the normally small size of neuronal, muscle, and hypodermal nucleoli, and is already active in 4-cell embryos; NCL-1 may be a repressor of RNA polymerase I and III transcription and an inhibitor of cell growth, based on mutant analysis; ncl-1 animals have much larger neuronal nucleoli than normal, somewhat larger muscle and hypodermal nucleoli, but essentially normal intestinal and germline nucleoli (the last of which are large even in wild-type animals); conversely, intestinal and germline cells have the lowest amounts of NCL-1 protein; ncl-1 animals are 9% larger, have 22% more protein and twice as much rRNA, and transcribe rRNA twice as much as wild-type worms; ncl-1 functions cell autonomously, and ncl-1 mutations suppress the tumorous germline phenotype of pro-1(na48) mutants.
22	srh-166	Y38H6C.12	n/a	chrV 20,520,671	C. elegans SRH-166 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
23	H32C10.3	H32C10.3	n/a	chrIV 5,918,692	contains similarity to Pfam domains PF00023 (Ankyrin repeat) (5), PF01529 (DHHC zinc finger domain) contains similarity to Interpro domains IPR001594 (Zinc finger, DHHC-type), IPR002110 (Ankyrin)
24	ubc-24	F49E12.4	n/a	chrII 8,406,159	ubc-24 encodes a predicted conjugating enzyme (UBCs/E2s) of the ubiquitin-conjugation system.
25	C35E7.7	C35E7.7	n/a	chrI 10,814,340
26	W07G4.2	W07G4.2	n/a	chrV 13,035,710	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
27	clec-99	ZK39.8	n/a	chrI 11,157,780	C. elegans CLEC-99 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
28	Y23H5A.4	Y23H5A.4	n/a	chrI 2,618,955	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
29	Y45F3A.1	Y45F3A.1	n/a	chrIII 10,559,860	contains similarity to Homo sapiens Tropomyosin 2; ENSEMBL:ENSP00000367550
30	F28B1.1	F28B1.1	n/a	chrV 17,043,156	contains similarity to Mus musculus Hypothetical protein.; TR:Q8C3I4
31	F16G10.2	F16G10.2	n/a	chrII 2,375,633	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
32	F58F9.6	F58F9.6	n/a	chrIV 6,236,744	contains similarity to Interpro domain IPR000884 (Thrombospondin, type I)
33	Y48B6A.5	Y48B6A.5	n/a	chrII 14,173,958	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
34	C25A8.5	C25A8.5	n/a	chrIV 7,000,530	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF00017 (SH2 domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
35	C16D9.5	C16D9.5	n/a	chrV 8,244,484	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
36	nhr-225	T27B7.2	n/a	chrV 2,289,169	C. elegans NHR-225 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
37	C32H11.9	C32H11.9	n/a	chrIV 12,935,630	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
38	F59B2.12	F59B2.12	n/a	chrIII 9,019,194	contains similarity to Homo sapiens Similar to Dentin sialophosphoprotein preproprotein; ENSEMBL:ENSP00000282478
39	Y116A8C.38	Y116A8C.38	n/a	chrIV 17,132,537	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF00017 (SH2 domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
40	C49G7.1	C49G7.1	n/a	chrV 4,057,600	contains similarity to Pfam domains PF00023 (Ankyrin repeat) , PF00533 (BRCA1 C Terminus (BRCT) domain) contains similarity to Interpro domains IPR002110 (Ankyrin), IPR001357 (BRCT)
41	F16G10.3	F16G10.3	n/a	chrII 2,373,286	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
42	gcy-12	F08B1.2	n/a	chrII 5,314,665	gcy-12 encodes a membrane guanylyl cyclase; a gcy-12::GFP reporter is expressed in the PHA neurons as well as in a number of head sensory neurons including AFD, AWC, and ASE; when expressed in COS-M6 cells, GCY-12 exhibits temperature-dependent guanylyl cyclase activity.
43	F35C5.1	F35C5.1	n/a	chrII 12,881,287	contains similarity to Saccharomyces cerevisiae B-type regulatory subunit of protein phosphatase 2A (PP2A); SGD:YOR014W
44	C05B5.1	C05B5.1	n/a	chrIII 9,987,900	contains similarity to Clostridium acetobutylicum Membrane associated chemotaxis sensory transducer protein (MSPsdomain and HAMP domain).; TR:Q97JD4
45	Y47H9B.2	Y47H9B.2	n/a	chrI 11,745,783	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
46	ani-1	Y49E10.19	n/a	chrIII 12,449,658	ani-1 encodes one of three C. elegans anillins; ANI-1 activity is required in the early embryo for cortical contractile events, including polar body extrusion, membrane ruffling, and pseudocleavage; at later stages of development, ANI-1 also plays a role in cuticle formation, coordinated locomotion, vulval development, and male tail formation; in regulating cortical events, ANI-1 appears to function by positively regulating septin (UNC-59 and UNC-61) localization to the contractile ring as well as formation of septin- and NMY-2-containing cortical patches; in telophase embryos, ANI-1 localizes to the cell cortex and cleavage furrow.
47	C18G1.3	C18G1.3	n/a	chrV 4,762,839	contains similarity to Interpro domain IPR000694 (Proline-rich region)
48	C24D10.1	C24D10.1	n/a	chrIV 5,167,373	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
49	T05C12.9	T05C12.9	n/a	chrII 8,192,426	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF02149 (Kinase associated domain 1) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR001772 (Kinase-associated KA1), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR015940 (Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)
50	C33E10.6	C33E10.6	n/a	chrX 17,268,242	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q227I5