UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	sri-27	ZK697.4	0	chrV 1,726,643	C. elegans SRI-27 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
2	C18B10.6	C18B10.6	n/a	chrV 7,480,150	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
3	T19C9.8	T19C9.8	n/a	chrV 17,239,506	contains similarity to Amsacta moorei entomopoxvirus AMV141.; TR:Q9EMQ8
4	str-7	F22B8.5	0.000000005	chrV 16,098,738	C. elegans STR-7 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
5	T07C4.10	T07C4.10	n/a	chrIII 10,323,248	contains similarity to Interpro domains IPR002957 (Keratin, type I), IPR000533 (Tropomyosin), IPR009053 (Prefoldin)
6	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
7	F55C10.4	F55C10.4	n/a	chrV 11,387,665	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
8	pps-1	T14G10.1	n/a	chrIV 10,163,166	pps-1 is orthologous to human PAPSS1 (OMIM:603262) and human PAPSS2 (OMIM:603005, mutated in spondyloepimetaphyseal dysplasia).
9	T24D1.2	T24D1.2	n/a	chrI 9,954,687	contains similarity to Interpro domain IPR001841 (Zinc finger, RING-type)
10	D1081.3	D1081.3	n/a	chrI 8,466,325	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
11	H06O01.2	H06O01.2	n/a	chrI 7,012,174	H06O01.2 encodes a large (1,461-aa) putative chromodomain helicase DNA-binding protein that inhibits DHC-1 in vivo; H06O01.2 is orthologous to budding yeast CHD1, human CHD1 (OMIM:602118), and human CHD2 (OMIM:602119); H06O01.2(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that H06O01.2 negatively regulates dynein; H06O01.2 has no obvious function in mass RNAi assays.
12	C15H9.3	C15H9.3	n/a	chrX 6,116,887	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domain IPR000276 (GPCR, rhodopsin-like)
13	C54E10.1	C54E10.1	n/a	chrV 18,816,778	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
14	C18B2.6	C18B2.6	n/a	chrX 3,615,375	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
15	T20G5.10	T20G5.10	n/a	chrIII 10,211,438	contains similarity to Pfam domain PF06320 GCN5-like protein 1 (GCN5L1) contains similarity to Interpro domain IPR009395 (GCN5-like 1)
16	C49C3.5	C49C3.5	n/a	chrIV 17,329,906	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
17	W03G1.3	W03G1.3	n/a	chrIV 512,107
18	F35H12.4	F35H12.4	n/a	chrX 922,380	contains similarity to Pfam domain PF00454 Phosphatidylinositol 3- and 4-kinase contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR000403 (Phosphatidylinositol 3- and 4-kinase, catalytic), IPR015433 (Phosphatidylinositol Kinase)
19	mrp-2	F57C12.4	n/a	chrX 568,214	mrp-2 encodes a predicted multidomain transmembrane protein that is a member of the ATP-binding cassette (ABC) superfamily of transport proteins and is homologous to the human multidrug resistance-associated protein 1 (MRP1, OMIM:158343); by homology, MRP-2 is predicted to function as a membrane pump that couples the energy of ATP hydrolysis to membrane transport; as loss of MRP-2 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of MRP-2 in C. elegans development and/or behavior is not yet known; mrp-2 expression is, however, upregulated early in the exit from the alternative dauer stage and then remains induced, suggesting that MRP-2 activity is required for the transition to, and maintenance of, a more active metabolic state.
20	sup-12	T22B2.4	n/a	chrX 3,906,111	sup-12 encodes an RNA-binding protein that contains a conserved RNA recognition motif (RRM); during development, SUP-12 functions to regulate muscle-specific splicing of alternative unc-60 and egl-15 pre-mRNAs; in vitro, SUP-12 can bind unc-60 and egl-15 pre-mRNAs; a sup-12::gfp promoter fusion is expressed in body wall muscle and in the pharynx; in body wall muscle, a SUP-12::GFP localizes to nuclei in a speckled pattern.
21	Y39A3A.2	Y39A3A.2	n/a	chrIII 2,057,188	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold)
22	T23G4.3	T23G4.3	n/a	chrIV 13,686,045	contains similarity to Homo sapiens BAG-family molecular chaperone regulator-4; ENSEMBL:ENSP00000287322
23	C11D2.3	C11D2.3	n/a	chrIV 6,154,348
24	K09F6.3	K09F6.3	n/a	chrII 2,258,704	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR003125 (Protein of unknown function WSN)
25	Y51B9A.5	Y51B9A.5	n/a	chrII 9,404,343	contains similarity to Mus musculus Laminin gamma-1 chain precursor (Laminin B2 chain).; SW:LMG1_MOUSE
26	his-43	F08G2.2	n/a	chrII 13,827,426	his-43 encodes an H2A histone.
27	ZK1193.3	ZK1193.3	n/a	chrX 418,922	contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR013032 (EGF-like region, conserved site)
28	F30A10.6	F30A10.6	n/a	chrI 9,490,547	contains similarity to Pfam domain PF02383 SacI homology domain contains similarity to Interpro domain IPR002013 (Synaptojanin, N-terminal)
29	B0495.9	B0495.9	n/a	chrII 7,708,071
30	T15B7.13	T15B7.13	n/a	chrV 6,827,999	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
31	R05H11.1	R05H11.1	n/a	chrIII 6,796,617	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
32	F49F1.7	F49F1.7	n/a	chrIV 4,124,635	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
33	F41E6.9	F41E6.9	n/a	chrV 8,605,583	contains similarity to Pfam domain PF03357 Snf7 contains similarity to Interpro domain IPR005024 (Snf7)
34	K08D10.5	K08D10.5	n/a	chrIV 4,168,957	contains similarity to Rhodopirellula baltica DNA-binding protein SMUBP-2.; TR:Q7UWP1
35	F32H2.8	F32H2.8	n/a	chrI 8,992,131	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domains IPR004988 (Protein of unknown function DUF273), IPR002229 (Blood group Rhesus C/E and D polypeptide)
36	fbxa-51	T12B5.1	n/a	chrIII 962,902	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
37	C27H6.3	C27H6.3	n/a	chrV 9,981,996	contains similarity to Homo sapiens Acidic (Leucine-rich) nuclear phosphoprotein 32 family, member E; ENSEMBL:ENSP00000358111
38	smg-5	W02D3.8	n/a	chrI 6,735,096	smg-5 encodes a novel protein that contains two N-terminal tetratricopeptide (TPR) repeats and a C-terminal PINc domain found in nucleotide-binding proteins; SMG-5 is a component of the nonsense-mediated mRNA decay (NMD) pathway and likely functions in regulation of dephosphorylation of SMG-2, the C. elegans UPF1 ortholog, an ATPase and RNA helicase required for NMD in worms, yeast, and mammals; SMG-5 physically interacts with SMG-7, SMG-2, and the PAA-1 and LET-92 structural and catalytic subunits, respectively, of a protein phosphatase 2A (PP2A), suggesting that SMG-5 may function to direct SMG-2 to a PP2A phosphatase that regulates its activity in vivo; SMG-5 also interacts, in vivo, with components of the RNA interference (RNAi) pathway, suggesting a potential link between RNAi and NMD; SMG-5::GFP fusion proteins localize to both the nucleus and the cytoplasm.
39	clec-144	T27D12.3	n/a	chrII 11,831,976	C. elegans CLEC-144 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
40	ZK1098.4	ZK1098.4	n/a	chrIII 9,543,651	contains similarity to Pfam domain PF01008 Initiation factor 2 subunit family contains similarity to Interpro domain IPR000649 (Initiation factor 2B related)
41	T15D6.11	T15D6.11	n/a	chrI 12,397,457	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
42	srw-88	T06G6.7	n/a	chrI 12,721,084	C. elegans SRW-88 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
43	K07C5.2	K07C5.2	n/a	chrV 10,340,201	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
44	spr-1	D1014.8	n/a	chrV 8,128,020	spr-1 encodes the C. elegans ortholog of the human corepressor CoREST that functions in HDAC-containing complexes to mediate transcriptional repression; in C. elegans, spr-1 was first identified in screens for genetic suppressors of the egg-laying defective phenotype of sel-12/presenilin mutants; subsequent genetic analyses showed that spr-1 likely functions as a negative regulator of LIN-12/Notch signaling in multiple cells, including those of the somatic gonad, vulva, and early embryo; spr-1 also interacts genetically with sem-5 to regulate postembryonic growth rates and lin-35Rb to regulate vulval morphogenesis and germline proliferation; in binding assays and yeast two-hybrid experiments, SPR-1 interacts with SPR-5, the C. elegans ortholog of the LSD1 histone demethylase; an SPR-1::MYC fusion protein expressed under the control of the cog-2 promoter localizes to the nucleus and shows increased staining in nuclear speckles and what appears to be the nucleolus.
45	T11G6.3	T11G6.3	n/a	chrIV 10,853,967	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
46	T16G12.6	T16G12.6	n/a	chrIII 10,072,699	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
47	T20F5.3	T20F5.3	n/a	chrI 3,910,087	contains similarity to Pfam domain PF01765 Ribosome recycling factor contains similarity to Interpro domains IPR002661 (Ribosome recycling factor), IPR001669 (Arginine repressor)
48	cyp-14A1	K09A11.2	n/a	chrX 13,266,131	C. elegans CYP-14A1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
49	ced-11	ZK512.3	n/a	chrIII 9,122,267	The ced-11 gene encodes a predicted transmembrane ion channel related to the long transient receptor potential channel (LTRPC) subfamily of TRP channels found in Drosophila and mammals; CED-11 functions as a downstream effector in the programmed cell death pathway and may play a role in affecting the morphological changes seen in the nucleus, cytoplasm, and plasma membrane of apoptotic cells.
50	C26E1.3	C26E1.3	n/a	chrV 13,303,181	contains similarity to Interpro domains IPR001356 (Homeobox), IPR009057 (Homeodomain-like)