UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZK666.8	ZK666.8	0	chrII 10,492,235	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	W01B6.6	W01B6.6	n/a	chrIV 10,081,890	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
4	fat-5	W06D12.3	n/a	chrV 17,725,852	fat-5 encodes a delta-9 fatty acid desaturase that is predicted to be mitochondrial; when expressed heterologously in S. cerevisiae, FAT-5 rescues the fatty acid auxotrophy of the yeast delta-9 desaturase mutant ole1.
5	clec-59	ZK666.5	n/a	chrII 10,478,656	C. elegans CLEC-59 protein; contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002035 (von Willebrand factor, type A)
6	F20D6.10	F20D6.10	n/a	chrV 8,193,961	contains similarity to Homo sapiens Protein FAM133A; ENSEMBL:ENSP00000318974
7	R06B9.1	R06B9.1	n/a	chrII 13,764,398	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR000698 (Arrestin), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
8	C13G5.2	C13G5.2	n/a	chrIII 8,617,549	contains similarity to Interpro domain IPR001680 (WD40 repeat)
9	F35E8.13	F35E8.13	n/a	chrV 15,925,673	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
10	lact-2	ZK945.1	n/a	chrII 10,096,751	lact-2 encodes a beta-lactamase domain-containing protein that contains a predicted transmembrane domain in its N terminus.
11	F20D6.2	F20D6.2	n/a	chrV 8,186,659	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
12	F36G9.7	F36G9.7	n/a	chrV 15,968,760	contains similarity to Methanosarcina mazei Hypothetical protein MM0083.; TR:Q8Q0Q3
13	ins-7	ZK1251.2	n/a	chrIV 9,682,219	ins-7 encodes an insulin/IGF-1-like peptide; INS-7 is one of 40 insulin-like peptides in C. elegans; INS-7 likely functions as an agonist for the DAF-2 insulin/IGF-1 receptor, as loss of ins-7 activity via RNAi results in: 1) a significantly increased lifespan that is not further extended in long-lived daf-2 mutant animals, and 2) an increased frequency of dauer formation in animals containing an incompletely penetrant daf-2 mutation; an ins-7 promoter fusion is expressed in amphid sensory neurons, labial neurons, the nerve ring, and ventral cord and tail neurons; ins-7 expression is positively regulated by DAF-2-mediated insulin signaling, suggesting that a positive feedback loop involving INS-7 may amplify DAF-2 pathway activity.
14	ncx-8	C13D9.7	n/a	chrV 4,985,459	ncx-8 encodes a putative Na[+]/Ca[2+] exchanger of uncertain stoichiometry and affinity, orthologous to human SLC24A6 and paralogous to NCX-6/-7 and NCX-9/-10; NCX-8 may function intracellularly; NCX-8 has tandem Calx-alpha domains predicted to carry out ion transport; NCX-8 is required for normally high levels of body fat.
15	nlp-2	T24D8.5	n/a	chrX 2,344,350	C. elegans NLP-2 protein ;
16	thn-1	F28D1.3	n/a	chrIV 12,380,448	C. elegans THN-1 protein; contains similarity to Pfam domain PF00314 Thaumatin family contains similarity to Interpro domain IPR001938 (Thaumatin, pathogenesis-related)
17	F09B9.4	F09B9.4	n/a	chrX 10,161,110	contains similarity to Interpro domain IPR003993 (Treacher Collins syndrome, treacle)
18	T28H10.3	T28H10.3	n/a	chrV 12,513,961	contains similarity to Pfam domain PF01650 Peptidase C13 family contains similarity to Interpro domain IPR001096 (Peptidase C13, legumain)
19	old-2	ZK938.5	n/a	chrII 9,848,462	old-2 encodes a transmembrane protein tyrosine kinase (also known as 'kin-28') that affects mean and maximum life span with multiple paralogs in C. elegans; the expression of old-2 was experimentally verified by RT-PCR.
20	sra-37	T21H8.2	n/a	chrX 13,892,086	C. elegans SRA-37 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
21	ZK550.5	ZK550.5	n/a	chrIV 17,258,404	contains similarity to Pfam domain PF05721 Phytanoyl-CoA dioxygenase (PhyH) contains similarity to Interpro domain IPR008775 (Phytanoyl-CoA dioxygenase)
22	M176.8	M176.8	n/a	chrII 9,437,409	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
23	F45E1.4	F45E1.4	n/a	chrX 7,986,049
24	C05D11.13	C05D11.13	n/a	chrIII 6,443,485	contains similarity to Drosophila melanogaster Flybase gene name is CG2839-PA;; FLYBASE:CG2839
25	srd-26	T02B5.4	n/a	chrV 14,162,174	C. elegans SRD-26 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
26	pax-3	F27E5.2	n/a	chrII 10,149,568	pax-3 encodes a divergent paired-like homeodomain protein that does not belong to the Q50, K50, or S50 classes; PAX-3 is required for locomotion and vulval development; pax-3(RNAi) animals have consistent Pvl and Unc phenotypes (as well as less consistent Bmd, Rup, and Stp phenotypes).
27	Y51A2B.1	Y51A2B.1	n/a	chrV 18,373,264	contains similarity to Pfam domain PF08719 Domain of unknown function (DUF1768) contains similarity to Interpro domains IPR012816 (Conserved hypothetical protein CHP02464), IPR016160 (Aldehyde dehydrogenase, conserved site)
28	C06A5.6	C06A5.6	n/a	chrI 5,984,551
29	Y57G11C.20	Y57G11C.20	n/a	chrIV 14,844,297	contains similarity to Interpro domain IPR000003 ()
30	cpr-3	T10H4.12	n/a	chrV 15,297,739	C. elegans CPR-3 protein; contains similarity to Pfam domain PF00112 Papain family cysteine protease contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR000668 (Peptidase C1A, papain C-terminal)
31	clec-79	F47C12.4	n/a	chrIV 3,974,525	C. elegans CLEC-79 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR000538 (Link), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
32	F47B8.6	F47B8.6	n/a	chrV 14,329,569	contains similarity to Drosophila heteroneura Aminopeptidase N (Fragment).; TR:O61534
33	hdl-1	ZK829.2	n/a	chrIV 11,947,905	C. elegans HDL-1 protein; contains similarity to Pfam domain PF00282 Pyridoxal-dependent decarboxylase conserved domain contains similarity to Interpro domains IPR002129 (Pyridoxal phosphate-dependent decarboxylase), IPR010977 (Aromatic-L-amino-acid decarboxylase), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
34	F15E6.4	F15E6.4	n/a	chrIV 4,291,666
35	F32D8.3	F32D8.3	n/a	chrV 10,887,380	F32D8.3 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; F32D8.3 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; F32D8.3 has no obvious function in mass RNAi assays.
36	Y42A5A.3	Y42A5A.3	n/a	chrV 11,095,685	contains similarity to Bacillus subtilis Hypothetical protein yhen.; TR:O07596
37	C34C6.3	C34C6.3	n/a	chrII 8,692,922	contains similarity to Pfam domains PF00008 (EGF-like domain) , PF07974 (EGF-like domain) contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR000585 (Hemopexin), IPR006209 (EGF-like), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR005018 (DOMON related), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular)
38	glt-5	Y53C12A.2	n/a	chrII 9,707,756	glt-5 encodes an ortholog of glutamate/aspartate and neutral amino acid transporters.
39	C07A9.8	C07A9.8	n/a	chrIII 9,688,522	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
40	C13A2.10	C13A2.10	n/a	chrV 7,274,350	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
41	F35H8.1	F35H8.1	n/a	chrII 9,552,878	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8ILJ6
42	F26D11.2	F26D11.2	n/a	chrV 7,960,124
43	T28F4.4	T28F4.4	n/a	chrI 7,488,371	contains similarity to Brugia malayi Putative uncharacterized protein BMBAC01P19.05a.; TR:Q8IHI4
44	F46G11.2	F46G11.2	n/a	chrX 5,789,196
45	srx-56	C03G6.2	n/a	chrV 7,374,979	C. elegans SRX-56 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
46	mab-9	T27A1.6	n/a	chrII 518,813	mab-9 encodes a member of the T-box family of transcriptional regulators containing a 200-amino acid T-box DNA-binding domain most similar to mouse Brachyury; mab-9 is involved in hindgut and male tail development, specifically affecting the fate of two posterior blast cells in the hindgut, B and F; in the male this results in a grossly abnormal tail lacking spicules, and renders them incapable of mating; in the hermaphrodite this results in hindgut defects; mab-9 may also be part of a network of T-box genes that includes tbx-8, tbx-9 and vab-7 and is important for the correct patterning of posterior cells in the developing embryo; mab-9 affects movement to some extent though the basis for this defect is unknown; MAB-9 localizes to the nucleus of B and F and their descendents during development.
47	twk-2	T12C9.3	n/a	chrII 4,447,199	twk-2 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; the precise role of TWK-2 in C. elegans development and/or behavior is not yet known, but TWK-2 may function redundantly with other TWK channels; TWK-2 is expressed in a subset of neurons.
48	W07A12.4	W07A12.4	n/a	chrII 9,150,253	contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF07707 (BTB And C-terminal Kelch) contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ), IPR011705 (BTB/Kelch-associated), IPR013089 (Kelch related)
49	T25B9.6	T25B9.6	n/a	chrIV 10,759,435	contains similarity to Interpro domain IPR006162 (Phosphopantetheine attachment site)
50	srw-33	T26H5.5	n/a	chrV 15,450,551	C. elegans SRW-33 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300), IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000276 (GPCR, rhodopsin-like)