UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	clec-60	ZK666.6	0	chrII 10,480,905	clec-60 encodes a C-type lectin protein with no obvious non-nematode orthologs required for normal resistance to infection with Microbacterium nematophilum; clec-60 transcription is induced 6.6-fold by infection with M. nematophilum, making it one of the most strongly infection-responsive genes (second only to tts-1), while not being induced by other pathogens; CLEC-60 is expressed throughout the larval intestine, continuing adult expression primarily in the posterior intestinal cells int8 and int9; CLEC-60 contains an N-terminal von Willebrand factor type A domain and a C-terminal C-type lectin domain; CLEC-60 has no obvious function in mass RNAi assays, and is dispensable for viability.
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	col-102	C18H7.3	n/a	chrIV 605,160	col-102 encodes a cuticle collagen.
4	F47B8.8	F47B8.8	n/a	chrV 14,332,167	contains similarity to Pfam domain PF01433 Peptidase family M1 contains similarity to Interpro domain IPR014782 (Peptidase M1, membrane alanine aminopeptidase, N-terminal)
5	nlp-20	F45E4.8	n/a	chrIV 7,642,623	nlp-20 encodes a predicted neuropeptide of the FAFA family; expressed in pharyngeal neurons.
6	C50F4.8	C50F4.8	n/a	chrV 9,518,171
7	col-35	C15A11.1	n/a	chrI 7,386,359	col-35 encodes a collagen that is individually dispensable for viability and gross morphology in mass RNAi screens; the amino- and carboxyl-terminal cysteine-rich regions of COL-35 are most closely related to those of COL-8, COL-19, and COL-39.
8	F17C11.4	F17C11.4	n/a	chrV 10,952,702	contains similarity to Mus musculus Desmoglein 2 precursor.; SW:DSG2_MOUSE
9	W05B2.4	W05B2.4	n/a	chrIII 10,975,818	contains similarity to Pfam domain PF08393 Dynein heavy chain, N-terminal region 2 contains similarity to Interpro domains IPR011010 (DNA breaking-rejoining enzyme, catalytic core), IPR013602 (Dynein heavy chain, N-terminal region 2)
10	col-183	F02D10.1	n/a	chrX 13,467,159	C. elegans COL-183 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002486 (Nematode cuticle collagen, N-terminal), IPR003979 (Tropoelastin), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
11	F53A9.8	F53A9.8	n/a	chrX 8,718,676	contains similarity to Plasmodium chabaudi Pc-fam-3 protein putative (Fragment).; TR:Q4XGP3
12	clec-13	H16D19.1	n/a	chrI 12,635,846	C. elegans CLEC-13 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
13	F43H9.4	F43H9.4	n/a	chrV 8,027,713	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
14	F56H9.2	F56H9.2	n/a	chrV 12,637,872	contains similarity to Plasmodium falciparum Transport protein, putative.; TR:Q8IHR3
15	W03D2.6	W03D2.6	n/a	chrIV 4,057,478
16	F07C4.6	F07C4.6	n/a	chrV 7,627,266	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
17	grl-19	R02D3.6	n/a	chrIV 252,252	grl-19 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-19 is expressed in intestine; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
18	C06E4.8	C06E4.8	n/a	chrIV 7,284,853	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
19	clec-1	F25B4.9	n/a	chrV 5,700,529	C. elegans CLEC-1 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002353 (Type II antifreeze protein)
20	ugt-27	C10H11.5	n/a	chrI 4,725,415	C. elegans UGT-27 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
21	srr-8	C13D9.3	n/a	chrV 5,002,438	C. elegans SRR-8 protein; contains similarity to Pfam domain PF03268 Caenorhabditis protein of unknown function, DUF267 contains similarity to Interpro domain IPR004950 (Protein of unknown function DUF267, Caenorhabditis species)
22	skr-5	F47H4.10	n/a	chrV 17,348,283	The skr-5 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-5(RNAi) animals are at least superficially normal.
23	C45B2.3	C45B2.3	n/a	chrX 6,083,106
24	T20D4.11	T20D4.11	n/a	chrV 3,399,039	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
25	B0304.2	B0304.2	n/a	chrII 4,524,073
26	F40F8.3	F40F8.3	n/a	chrII 11,129,630	contains similarity to Homo sapiens 17 kDa protein; ENSEMBL:ENSP00000373249
27	col-40	T13B5.4	n/a	chrII 1,105,772	col-40 encodes a cuticle collagen protein that belongs to the col-6 cuticle collagen family; col-40 transcript is present in L1 larvae and at the L2d-dauer molt.
28	col-158	D2023.7	n/a	chrV 11,830,378	C. elegans COL-158 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
29	T01C3.4	T01C3.4	n/a	chrV 14,994,531	contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
30	ZC196.2	ZC196.2	n/a	chrV 8,740,693	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
31	scl-2	F49E11.10	n/a	chrIV 13,058,350	C. elegans SCL-2 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
32	nas-20	T11F9.3	n/a	chrV 11,471,595	nas-20 encodes an astacin-like metalloprotease.
33	nlp-39	C54C8.9	n/a	chrI 12,461,774	C. elegans NLP-39 protein ;
34	F49H6.5	F49H6.5	n/a	chrV 17,024,380	The F49H6.5 gene encodes a homolog of the human gene MOCS1A, which when mutated leads to molybdenum cofactor deficiency (OMIM:252150).
35	F58H7.5	F58H7.5	n/a	chrIV 920,399
36	F53A9.1	F53A9.1	n/a	chrX 8,711,652	contains similarity to Interpro domains IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR002395 (HMW kininogen)
37	thn-2	F28D1.5	n/a	chrIV 12,383,557	C. elegans THN-2 protein; contains similarity to Pfam domain PF00314 Thaumatin family contains similarity to Interpro domain IPR001938 (Thaumatin, pathogenesis-related)
38	F35F10.1	F35F10.1	n/a	chrV 3,317,203	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
39	col-116	F17E9.1	n/a	chrIV 8,357,297	C. elegans COL-116 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
40	tag-68	F37D6.6	n/a	chrI 10,503,512	C. elegans TAG-68 protein; contains similarity to Pfam domains PF03166 (MH2 domain) , PF03165 (MH1 domain) contains similarity to Interpro domains IPR013019 (MAD homology, MH1), IPR008984 (SMAD/FHA domain), IPR001132 (SMAD domain, Dwarfin-type), IPR017855 (SMAD domain-like), IPR013790 (Dwarfin), IPR003619 (MAD homology 1, Dwarfin-type)
41	ttr-1	K03H1.6	n/a	chrIII 9,929,635	ttr-1 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; although TTR-1 belongs to a family of apparently nematode-specific proteins whose function is not yet known, loss of ttr-1 function via RNAi can result in enhanced dauer formation and daf-16-dependent lifespan extension.
42	F29G9.1	F29G9.1	n/a	chrV 6,040,023
43	F57F4.2	F57F4.2	n/a	chrV 6,388,125	contains similarity to Felis silvestris catus RPGR (Fragment).; TR:Q56PC0
44	Y20C6A.1	Y20C6A.1	n/a	chrV 17,374,108	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
45	hsp-12.3	F38E11.1	n/a	chrIV 9,445,065	hsp-12.3 encodes a small heat-shock protein that forms heterotetramers with HSP-12.2 and has no chaperone-like activity; structurally, HSP-12.3 is mostly a beta-sheet; at least one HSP-12 (which may or may not be HSP-12.2) is ubiquitously expressed in L1 larvae, and later expressed in adult spermatids (and perhaps spermatocytes), and some adult vulval cells; hsp-12.3 is upregulated in daf-2 mutants, suggesting that hsp-12.3's expression may contribute to prolonged lifespan in dauer larvae.
46	nlp-28	B0213.3	n/a	chrV 3,988,091	C. elegans NLP-28 protein ; contains similarity to Ixodes scapularis Putative secreted salivary gland peptide.; TR:Q5Q982
47	ocr-3	T10B10.7	n/a	chrX 15,171,101	ocr-3 encodes a predicted TRPV channel (transient receptor potential cation channel, subfamily V) containing six membrane-spanning regions, cytoplasmic ankyrin repeats, and a long, unconserved cytoplasmic tail that is related to the mammalian TRPV1 cation channel (OMIM:602076) activated by capsaicin and other noxious stimuli; although the precise role of OCR-3 in C. elegans development and/or behavior is not yet known, OCR-3 expression is detected solely in the rectal gland cells and occasionally the glial socket cells of the head, suggesting that OCR-3 may function in sensory signal transduction in these cell types.
48	DH11.2	DH11.2	n/a	chrII 8,013,966	contains similarity to Pfam domain PF00646 (F-box domain)
49	col-2	W01B6.7	n/a	chrIV 10,084,918	col-2 encodes a member of the collagen superfamily containing collagen triple helix repeats (20 copies); expression peaks during the molt that separates the L2 larval and dauer stages as the dauer cuticle is being formed, and mRNA is expressed at low levels in post-dauer L4 larvae and in adult animals.
50	srh-193	F47D2.9	n/a	chrV 4,289,288	C. elegans SRH-193 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)