UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZK666.1	ZK666.1	3e-66	chrII 10,471,061	contains similarity to Dictyostelium discoideum Hypothetical protein.; TR:Q8T282
2	F20B6.7	F20B6.7	n/a	chrX 4,207,129
3	srt-73	T06C10.2	n/a	chrIV 7,880,158	C. elegans SRT-73 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
4	clec-11	C54C8.7	n/a	chrI 12,460,190	C. elegans CLEC-11 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
5	mnm-2	C10A4.8	n/a	chrX 7,423,795	C. elegans MNM-2 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
6	C24H10.1	C24H10.1	n/a	chrX 5,073,103	C24H10.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; C24H10.1 is worm-specific, with obvious homologs only in C. elegans; C24H10.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
7	F35E2.2	F35E2.2	n/a	chrI 11,737,158	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
8	F44A6.3	F44A6.3	n/a	chrX 10,213,400	contains similarity to Human parainfluenza 1 virus RNA polymerase alpha subunit (EC 2.7.7.48) (Nucleocapsidsphosphoprotein).; SW:RRPP_PI1HB
9	C09G12.1	C09G12.1	n/a	chrIV 3,503,022	C09G12.1 encodes a paired-like homeodomain protein of the K50 class, which has no obvious function in mass RNAi assays.
10	C44C10.5	C44C10.5	n/a	chrX 11,691,705	contains similarity to Homo sapiens Structural maintenance of chromosomes protein 1A; ENSEMBL:ENSP00000323421
11	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
12	ver-1	T17A3.1	n/a	chrIII 160,182	C. elegans VER-1 protein; contains similarity to Pfam domains PF00047 (Immunoglobulin domain) (2), PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF07679 (Immunoglobulin I-set domain) (2)contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR013098 (Immunoglobulin I-set), IPR011009 (Protein kinase-like), IPR009134 (Vascular endothelial growth factor receptor, VEGFR, N-terminal), IPR003596 (Immunoglobulin V-set, subgroup), IPR013783 (Immunoglobulin-like fold), IPR000719 (Protein kinase, core), IPR007110 (Immunoglobulin-like), IPR003599 (Immunoglobulin subtype), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR013151 (Immunoglobulin)
13	str-83	B0213.7	n/a	chrV 3,978,022	C. elegans STR-83 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000344 (Nematode chemoreceptor, Sra), IPR003002 (7TM chemoreceptor, subfamily 1)
14	F59D12.3	F59D12.3	n/a	chrX 15,649,663	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
15	acr-9	C40C9.2	n/a	chrX 13,644,544	acr-9 encodes a predicted member of the alpha subunit family of nicotinic acetylcholine receptors.
16	srbc-13	K09C6.5	n/a	chrV 847,788	C. elegans SRBC-13 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
17	C07B5.6	C07B5.6	n/a	chrX 9,520,189	contains similarity to Helicobacter pylori Hypothetical protein HP1327.; TR:O25885
18	F07H5.6	F07H5.6	n/a	chrII 8,792,268	contains similarity to Interpro domain IPR002952 (Eggshell protein)
19	nhr-155	C14C6.4	n/a	chrV 540,344	C. elegans NHR-155 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
20	phat-1	C46H11.8	n/a	chrI 5,045,010	C. elegans PHAT-1 protein; contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
21	fbxb-50	K05F6.2	n/a	chrII 1,559,901	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
22	fkh-10	C25A1.2	n/a	chrI 10,164,375	fkh-10 encodes one of 15 forkhead transcriptional regulators encoded by the C. elegans genome; by homology, FKH-10 is predicted to function as a transcription factor that regulates gene expression during development; however, as loss of fkh-10 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of FKH-10 in C. elegans development and/or behavior is not yet known; nevertheless, reporter gene studies indicate that throughout larval and adult stages, fkh-10 expression is detected almost exclusively in six pairs of neuronal nuclei near the terminal bulb of the pharynx, suggesting that FKH-10 may have a specific function in neuronal differentiation.
23	fkb-7	B0511.1	n/a	chrI 10,669,451	fkb-7 encodes a peptidylprolyl cis/trans isomerase homologous to mammalian FK506-binding proteins; by homology, FKB-7 could function in a number of different processes including protein folding, signal transduction, and regulation of muscle contraction; however, as loss of fkb-7 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of FKB-7 in C. elegans development and/or behavior is not yet known.
24	srh-297	C17F4.4	n/a	chrII 3,229,698	C. elegans SRH-297 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR006084 (DNA repair protein (XPGC)/yeast Rad), IPR003002 (7TM chemoreceptor, subfamily 1)
25	clec-90	F57C9.2	n/a	chrI 4,846,413	C. elegans CLEC-90 protein; contains similarity to Interpro domains IPR002919 (Protease inhibitor I8, cysteine-rich trypsin inhibitor-like), IPR001304 (C-type lectin)
26	sdz-21	F54E7.5	n/a	chrIII 5,655,941	C. elegans SDZ-21 protein; contains similarity to Interpro domain IPR000480 (Glutelin)
27	evl-20	F22B5.1	n/a	chrII 8,444,637	evl-20 encodes a functional ortholog of human ADP-ribosylation factor-like protein 2 (ARL2; OMIM:601175), with evl-20(ar103) mutants being rescued by transgenic human ARL2 but not ARL1 or ARL3-7; EVL-20 is required for cortical microtubule formation during cytokinesis and morphogenesis; EVL-20 is required for vulval, gonadal, and male tail development, as well as for embryonic mitosis, hypodermal enclosure, and elongation; EVL-20 is expressed in migrating hypodermal embryonic cells, larval vulval and somatic gonad cells, larval and adult neurons, and adult male proctodeal cells, being subcellularly associated with both the cell cortex and astral microtubules.
28	JC8.4	JC8.4	n/a	chrIV 13,243,908	contains similarity to Pfam domain PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region contains similarity to Interpro domains IPR016192 (APOBEC/CMP deaminase, zinc-binding), IPR002125 (CMP/dCMP deaminase, zinc-binding), IPR016193 (Cytidine deaminase-like)
29	srw-112	K12D9.9	n/a	chrV 3,005,101	C. elegans SRW-112 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
30	lem-2	W01G7.5	n/a	chrII 14,064,559	C. elegans LEM-2 protein; contains similarity to Pfam domain PF03020 LEM domain contains similarity to Interpro domains IPR013142 (LEM-like region), IPR003887 (Lamino-associated polypeptide 2/emerin), IPR011015 (LEM-like fold)
31	ZK666.4	ZK666.4	1e-47	chrII 10,477,397	contains similarity to Oryza sativa Putative retinoblastoma-related protein 1.; TR:Q84QM3
32	F09F9.3	F09F9.3	n/a	chrX 4,120,310
33	Y73C8C.3	Y73C8C.3	n/a	chrV 3,116,714	contains similarity to Homo sapiens Isoform 3 of Centromeric protein E; ENSEMBL:ENSP00000369365
34	R13.2	R13.2	n/a	chrIV 10,826,996	contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
35	fbxb-34	W08F4.2	n/a	chrII 589,015	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
36	H01M10.2	H01M10.2	n/a	chrX 2,585,134	contains similarity to Interpro domain IPR006220 (Anthranilate synthase component II/delta crystallin)
37	str-229	C17E7.11	n/a	chrV 3,901,512	C. elegans STR-229 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
38	C49F5.3	C49F5.3	n/a	chrX 11,983,268	contains similarity to Phytophthora infestans SECY-independent transporter protein.; TR:Q9T238
39	fbxa-149	Y38H6C.10	n/a	chrV 20,512,556	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
40	fbxb-106	F29A7.1	n/a	chrII 2,763,216	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
41	W04A8.1	W04A8.1	n/a	chrI 13,837,656	W04A8.1 encodes a protein weakly similar to human microcephalin (MCPH1; OMIM:607117, mutated in primary microcephaly); while their primary sequence similarity is very subtle (only being detectable with psi-BLAST on NCBI-nr, using C. briggsae CBG13622 as a query sequence), both W04A8.1 and microcephalin has similar ordering of BRCT domains (one N-terminal, two C-terminal); W04A8.1 has no obvious function in mass RNAi screens.
42	T18D3.1	T18D3.1	n/a	chrX 12,456,267	contains similarity to Interpro domains IPR000009 (Protein phosphatase 2A, regulatory subunit PR55), IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
43	srv-19	H04M03.6	n/a	chrIV 5,873,058	C. elegans SRV-19 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
44	C09B8.5	C09B8.5	n/a	chrX 6,021,639
45	sre-8	F40G12.1	n/a	chrV 14,258,150	C. elegans SRE-8 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
46	sri-37	D2062.2	n/a	chrII 2,630,401	C. elegans SRI-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
47	Y40B1B.7	Y40B1B.7	n/a	chrI 13,427,466	contains similarity to Rattus norvegicus Coiled-coil domain-containing protein 86 (Cytokine-induced proteinswith coiled-coil domain).; SW:Q5XIB5
48	C03B1.9	C03B1.9	n/a	chrX 6,346,694
49	C28A5.5	C28A5.5	n/a	chrIII 4,451,510	contains similarity to Petunia hybrida PGPS/D8.; TR:Q9ZTN1
50	srw-142	H05B21.3	n/a	chrV 2,957,658	C. elegans SRW-142 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)