UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZK550.1	ZK550.1	0	chrIV 17,240,852	contains similarity to Pfam domain PF03062 MBOAT family contains similarity to Interpro domain IPR004299 (Membrane bound O-acyl transferase, MBOAT)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	F45E1.3	F45E1.3	n/a	chrX 7,987,677	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domain IPR005834 (Haloacid dehalogenase-like hydrolase)
4	R155.3	R155.3	n/a	chrIII 1,973,361	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR003016 (2-oxo acid dehydrogenase, lipoyl-binding site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
5	W09C3.1	W09C3.1	n/a	chrI 4,718,600	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
6	Y65A5A.2	Y65A5A.2	n/a	chrIV 16,413,511	contains similarity to Saccharomyces cerevisiae Required for invasion and pseudohyphae formation in response to nitrogen starvation; SGD:YIR019C
7	K06A1.3	K06A1.3	n/a	chrII 6,442,625	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
8	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
9	C17G10.3	C17G10.3	n/a	chrII 5,583,865
10	mgl-2	F45H11.4	n/a	chrI 10,387,757	mgl-2 encodes a Group I metabotropic glutamate receptor (OMIM:604473, 604102, loss-of-function mutations in mice are associated with defects in long-term potentiation); by homology, MGL-2 is predicted to function as a post-synaptic G protein-coupled receptor that, in response to glutamate binding, stimulates phospholipase C activity and increases neuronal excitation, and in mammalian tissue culture cells, glutamate stimulation of MGL-2 does result in increased phosphoinositide turnover; a mutation in mgl-2 indicates that it is required for normal head movements and tap reversal reflexes, while loss of mgl-2 activity via large-scale RNAi screens indicates that MGL-2 is also required for embryogenesis; a mgl-2::GFP reporter is expressed in interneurons.
11	snf-8	ZK829.10	n/a	chrIV 11,967,123	C. elegans SNF-8 protein; contains similarity to Pfam domain PF00209 Sodium:neurotransmitter symporter family contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR004354 (Meiotic recombination protein rec114)
12	tag-347	C25G4.4	n/a	chrIV 12,453,128	C. elegans TAG-347 protein; contains similarity to Pfam domains PF01342 (SAND domain) , PF02178 (AT hook motif) contains similarity to Interpro domains IPR000116 (High mobility group proteins HMG-I and HMG-Y), IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR010919 (SAND-like), IPR000770 (SAND)
13	T25B9.2	T25B9.2	n/a	chrIV 10,750,930	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
14	F26H9.8	F26H9.8	n/a	chrI 9,322,465	contains similarity to Pfam domains PF01501 (Glycosyl transferase family 8) , PF06427 (UDP-glucose:Glycoprotein Glucosyltransferase) contains similarity to Interpro domains IPR000886 (Endoplasmic reticulum, targeting sequence), IPR009448 (UDP-glucose:Glycoprotein Glucosyltransferase), IPR002495 (Glycosyl transferase, family 8)
15	C18H2.4	C18H2.4	n/a	chrIII 7,697,463	C18H2.4 is orthologous to the human gene GLOMULIN (FAP48; OMIM:601749), which when mutated leads to disease.
16	dsl-5	F58B3.8	n/a	chrIV 11,620,190	dsl-5 encodes a putative secreted protein with single DSL and EGF domains in series, somewhat like Delta/LAG-2; DSL-5 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-1, -2, -3, -5, -6, and -7.
17	F10C1.3	F10C1.3	n/a	chrII 5,757,653
18	ZK84.5	ZK84.5	n/a	chrII 6,016,343
19	M03E7.3	M03E7.3	n/a	chrV 5,615,596
20	F59B2.5	F59B2.5	n/a	chrIII 9,001,107	contains similarity to Pfam domain PF01399 PCI domain contains similarity to Interpro domains IPR013143 (PCI/PINT associated module), IPR011991 (Winged helix repressor DNA-binding), IPR000717 (Proteasome component region PCI)
21	K10D6.3	K10D6.3	n/a	chrV 11,201,218	contains similarity to Homo sapiens HMG-BOX transcription factor BBX; ENSEMBL:ENSP00000319742
22	T08G11.2	T08G11.2	n/a	chrI 8,919,920	T08G11.2 encodes a nematode-specific sperm protein, required for a normally high ovulation rate, that interacts with EGL-32; despite not being EGL-32, and although T08G11.2(tm336) complements egl-32(n155), T08G11.2 can partially rescue egl-32 mutants when expressed transgenically, implying that T08G11.2 can be a nonorthologous replacement for EGL-32 function in vivo; T08G11.2 has an SH2 motif, but this motif lacks a critical arginine residue; T08G11.2 has no obvious non-nematode homologs, but is paralogous to four other C. elegans proteins (B0207.11, F42G4.6, F44F4.10, and Y81G3A.1); T08G11.2(tm336) hermaphrodites have a lowered ovulation rate (and thus a lowered rate of egg-laying), retaining significantly fewer eggs than wild-type, yet also retaining late-stage embryos; T08G11.2 has no obvious phenotype in mass RNAi experiments, possibly because of genetic redundancy with its paralogs; T08G11.2 expression is strongly enriched in spermatogenesis.
23	H05L14.1	H05L14.1	n/a	chrI 7,974,757	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR017442 (Serine/threonine protein kinase-related)
24	rnh-1.1	ZK1290.6	n/a	chrII 7,526,915	C. elegans RNH-1.1 protein; contains similarity to Pfam domain PF00075 RNase H contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold), IPR002156 (Ribonuclease H)
25	F09C12.2	F09C12.2	n/a	chrII 5,111,113	F09C12.2 encodes a kinase most closely related to mitogen-activated protein (MAP) kinases; as loss of F09C12.2 activity via mutation or large-scale RNAi results in no obvious defects, the precise role of F09C12.2 in C. elegans development and/or behavior is not yet known.
26	R05D3.3	R05D3.3	n/a	chrIII 8,365,486
27	rmd-5	T23B3.3	n/a	chrI 6,711,598	C. elegans RMD-5 protein ; contains similarity to Xenopus laevis Protein FAM82C.; SW:Q5EAU9
28	ctl-1	Y54G11A.6	n/a	chrII 14,304,828	ctl-1 encodes one of three C. elegans catalases; CTL-1 exhibits catalase activity in vitro, and thus likely functions in vivo as an antioxidant enzyme that protects cells from reactive oxygen species; ctl-1 activity contributes to the extended lifespan seen in daf-2 mutant animals; in addition, ctl-1 expression is negatively regulated by DAF-2-mediated insulin signaling; as CTL-1 does not possess a C-terminal peroxisomal targeting signal (PTS), it is predicted to be a cytosolic catalase.
29	tat-3	W09D10.2	n/a	chrIII 10,725,682	C. elegans TAT-3 protein; contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006539 (Phospholipid-translocating P-type ATPase, flippase), IPR001757 (ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter), IPR005834 (Haloacid dehalogenase-like hydrolase)
30	C06G4.4	C06G4.4	n/a	chrIII 7,977,442
31	F59A3.7	F59A3.7	n/a	chrI 5,517,931
32	C38C6.5	C38C6.5	n/a	chrII 14,631,497	contains similarity to Interpro domain IPR001574 (Ribosome-inactivating protein)
33	W04A4.2	W04A4.2	n/a	chrI 13,683,368	contains similarity to Homo sapiens Hypothetical protein FLJ90033; TR:Q8N2R3
34	F25H5.7	F25H5.7	n/a	chrI 9,156,467	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
35	C09F9.1	C09F9.1	n/a	chrII 14,698,971	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
36	sur-6	F26E4.1	n/a	chrI 9,756,000	C. elegans SUR-6 protein; contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR000009 (Protein phosphatase 2A, regulatory subunit PR55), IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
37	R12E2.2	R12E2.2	n/a	chrI 4,180,486	contains similarity to Pfam domain PF07738 Sad1 / UNC-like C-terminal contains similarity to Interpro domains IPR012919 (Sad1/UNC-like, C-terminal), IPR008979 (Galactose-binding like)
38	F18A12.4	F18A12.4	n/a	chrII 3,405,348	F18A12.4 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F18A12.4 has no clear orthologs in other organisms.
39	F44D12.3	F44D12.3	n/a	chrIV 10,022,456	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
40	C07G1.6	C07G1.6	n/a	chrIV 8,209,489
41	F22D6.9	F22D6.9	n/a	chrI 7,100,795	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
42	ZC204.13	ZC204.13	n/a	chrII 1,660,734
43	kel-10	T16H12.6	n/a	chrIII 10,099,930	C. elegans KEL-10 protein; contains similarity to Pfam domains PF01344 (Kelch motif) (5), PF00651 (BTB/POZ domain) , PF07646 (Kelch motif) (2)contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR000210 (BTB/POZ-like), IPR006652 (Kelch repeat type 1), IPR011333 (BTB/POZ fold), IPR011498 (Kelch repeat type 2), IPR015916 (Galactose oxidase, beta-propeller), IPR013069 (BTB/POZ), IPR013089 (Kelch related), IPR006651 (Kelch), IPR015915 (Kelch-type beta propeller)
44	ugt-2	AC3.8	n/a	chrV 10,399,988	C. elegans UGT-2 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
45	F54F12.1	F54F12.1	n/a	chrIII 13,051,731	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000694 (Proline-rich region), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
46	R02D3.8	R02D3.8	n/a	chrIV 256,589	contains similarity to Pfam domain PF00929 Exonuclease contains similarity to Interpro domains IPR013520 (Exonuclease, RNase T and DNA polymerase III), IPR006055 (Exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
47	R07C3.4	R07C3.4	n/a	chrII 934,987	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
48	twk-37	C48E7.9	n/a	chrI 6,270,306	C. elegans TWK-37 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR003938 (Potassium channel, voltage-dependent, EAG/ELK/ERG), IPR013099 (Ion transport 2)
49	R03H10.4	R03H10.4	n/a	chrII 4,168,021	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
50	T03F6.4	T03F6.4	n/a	chrIII 13,387,131	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)