UCSC C. elegans Gene Sorter

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

UCSC C. elegans Gene Sorter

genome assembly search

sort by display output

#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	msp-152	ZK546.6	2e-73	chrII 4,933,207	msp-152 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
2	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
3	W09C3.1	W09C3.1	n/a	chrI 4,718,600	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
4	cyp-35B3	K07C6.2	n/a	chrV 3,946,183	C. elegans CYP-35B3 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
5	K02B2.3	K02B2.3	n/a	chrIV 5,938,425	contains similarity to Pfam domain PF04678 Protein of unknown function, DUF607 contains similarity to Interpro domain IPR006769 (Protein of unknown function DUF607)
6	T03F6.4	T03F6.4	n/a	chrIII 13,387,131	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
7	F56H1.5	F56H1.5	n/a	chrI 5,757,572	F56H1.5 encodes a putative ATP/ADP-activated metallocarboxypeptidase that may function in vivo as an alpha-tubulin C-terminal tyrosine carboxypeptidase; F56H1.5 is orthologous to murine AGTPBP-1/Nna1/pcd (upregulated in damaged mouse spinal cord and mutated in Purkinje cell degeneration) and human AGTPBP1 (OMIM:606830); murine AGTPBP-1 is genetically required for tubulin carboxypeptidase activity in vivo, and F56H1.5's nearest paralog EEED8.6 has biochemical traits consistent with tubulin carboxypeptidase activity; F56H1.5 and its mammalian AGTPBP1 orthologs, along with other proteins, comprise a M14D3 peptidase subfamily.
8	srp-5	C03G6.18	n/a	chrV 7,382,647	srp-5 encodes an ovalbumin-like serpin (ov-serpin) member of the serine protease inhibitor superfamily; by homology, SRP-5 is predicted to function as a suicide substrate that inhibits the proteolytic activity of serine proteases; however, as loss of srp-5 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of SRP-5 in C. elegans development and/or behavior is not yet known.
9	R02D3.8	R02D3.8	n/a	chrIV 256,589	contains similarity to Pfam domain PF00929 Exonuclease contains similarity to Interpro domains IPR013520 (Exonuclease, RNase T and DNA polymerase III), IPR006055 (Exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
10	srh-46	T03F7.3	n/a	chrV 11,302,223	C. elegans SRH-46 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	F55A11.7	F55A11.7	n/a	chrV 11,785,988	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
12	F15D3.6	F15D3.6	n/a	chrI 11,574,794	contains similarity to Pfam domain PF04707 PRELI-like family contains similarity to Interpro domain IPR006797 (MSF1)
13	twk-1	F21C3.1	n/a	chrI 7,270,700	C. elegans TWK-1 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2)
14	F10C1.3	F10C1.3	n/a	chrII 5,757,653
15	C05C9.2	C05C9.2	n/a	chrX 11,155,280	contains similarity to White spot syndrome virus WSSV326.; TR:Q8QTD0
16	Y37D8A.4	Y37D8A.4	n/a	chrIII 12,837,949	contains similarity to Pfam domain PF00017 SH2 domain contains similarity to Interpro domain IPR000980 (SH2 motif)
17	mgl-2	F45H11.4	n/a	chrI 10,387,757	mgl-2 encodes a Group I metabotropic glutamate receptor (OMIM:604473, 604102, loss-of-function mutations in mice are associated with defects in long-term potentiation); by homology, MGL-2 is predicted to function as a post-synaptic G protein-coupled receptor that, in response to glutamate binding, stimulates phospholipase C activity and increases neuronal excitation, and in mammalian tissue culture cells, glutamate stimulation of MGL-2 does result in increased phosphoinositide turnover; a mutation in mgl-2 indicates that it is required for normal head movements and tap reversal reflexes, while loss of mgl-2 activity via large-scale RNAi screens indicates that MGL-2 is also required for embryogenesis; a mgl-2::GFP reporter is expressed in interneurons.
18	wee-1.3	Y53C12A.1	n/a	chrII 9,715,024	C. elegans WEE-1.3 protein; contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
19	ech-5	F56B3.5	n/a	chrIV 798,439	C. elegans ECH-5 protein; contains similarity to Pfam domain PF00378 Enoyl-CoA hydratase/isomerase family contains similarity to Interpro domain IPR001753 (Crotonase, core)
20	dhs-30	T25G12.7	n/a	chrX 17,233,193	dhs-30 encodes a member of the short-chain dehydrogenases/reductases family (SDR) homologous to HSD, which when mutated leads to cortisol 11-beta ketoreductase deficiency (OMIM:218030).
21	K06A1.3	K06A1.3	n/a	chrII 6,442,625	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
22	lite-1	C14F11.3	n/a	chrX 6,228,375	C. elegans LITE-1 protein; contains similarity to Pfam domain PF08395 7tm Chemosensory receptor contains similarity to Interpro domains IPR009318 (Trehalose receptor), IPR013604 (7TM chemoreceptor)
23	C48E7.6	C48E7.6	n/a	chrI 6,244,688	contains similarity to Drosophila pseudoobscura GA10211-PA (Fragment).; TR:Q29MP8
24	dct-12	Y57A10C.7	n/a	chrII 12,431,464	C. elegans DCT-12 protein ;
25	clec-40	T20B3.13	n/a	chrV 16,840,047	C. elegans CLEC-40 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
26	C02G6.2	C02G6.2	n/a	chrV 5,873,482	contains similarity to Pfam domains PF00675 (Insulinase (Peptidase family M16)) , PF05193 (Peptidase M16 inactive domain) (2)contains similarity to Interpro domains IPR001431 (Peptidase M16, zinc-binding site), IPR011765 (Peptidase M16, N-terminal), IPR011237 (Peptidase M16, core), IPR007863 (Peptidase M16, C-terminal), IPR011249 (Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)
27	F35E12.8	F35E12.8	n/a	chrV 13,750,531	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003366 (CUB-like region)
28	str-232	T10C6.1	n/a	chrV 16,015,103	C. elegans STR-232 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
29	R12E2.2	R12E2.2	n/a	chrI 4,180,486	contains similarity to Pfam domain PF07738 Sad1 / UNC-like C-terminal contains similarity to Interpro domains IPR012919 (Sad1/UNC-like, C-terminal), IPR008979 (Galactose-binding like)
30	C10H11.8	C10H11.8	n/a	chrI 4,736,771	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
31	C18B12.1	C18B12.1	n/a	chrX 15,012,725	contains similarity to Bacillus anthracis Flagellar biosynthetic protein FlhB, putative.; TR:Q81SE5
32	F59A2.6	F59A2.6	n/a	chrIII 3,420,133	contains similarity to Pfam domains PF02524 (KID repeat) , PF01465 (GRIP domain) contains similarity to Interpro domains IPR004089 (Chemotaxis methyl-accepting receptor, signalling), IPR000533 (Tropomyosin), IPR009053 (Prefoldin), IPR000237 (GRIP)
33	F13E9.1	F13E9.1	n/a	chrIV 10,868,951	contains similarity to Pfam domains PF00560 (Leucine Rich Repeat) (4), PF00787 (PX domain) contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR001683 (Phox-like), IPR003591 (Leucine-rich repeat, typical subtype)
34	tat-3	W09D10.2	n/a	chrIII 10,725,682	C. elegans TAT-3 protein; contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006539 (Phospholipid-translocating P-type ATPase, flippase), IPR001757 (ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter), IPR005834 (Haloacid dehalogenase-like hydrolase)
35	acl-2	T06E8.1	n/a	chrV 10,029,692	T06E8.1 is orthologous to the human gene 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 2 (LYSOPHOSPHATIDIC ACID ACYLTRANSFERASE, BETA) (AGPAT2; OMIM:603100), which when mutated leads to disease; T06E8.1 protein is predicted to be mitochondrial.
36	rfc-1	C54G10.2	n/a	chrV 14,644,310	C. elegans RFC-1 protein; contains similarity to Pfam domains PF00004 (ATPase family associated with various cellular activities (AAA)) , PF08519 (Replication factor RFC1 C terminal domain) contains similarity to Interpro domains IPR013725 (DNA replication factor RFC1, C-terminal), IPR003959 (AAA ATPase, core), IPR008921 (DNA polymerase III clamp loader subunit, C-terminal), IPR012178 (DNA replication factor C, large subunit), IPR003593 (AAA+ ATPase, core), IPR001984 (Peptidase S16, Lon protease)
37	C50B8.1	C50B8.1	n/a	chrV 13,566,397	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
38	W02G9.5	W02G9.5	n/a	chrV 2,659,404	contains similarity to Pfam domain PF03372 Endonuclease/Exonuclease/phosphatase family contains similarity to Interpro domain IPR005135 (Endonuclease/exonuclease/phosphatase)
39	3R5.1	3R5.1	n/a	chrIII 13,780,560	contains similarity to Mus musculus Paired amphipathic helix protein Sin3a.; SW:SN3A_MOUSE
40	asm-1	B0252.2	n/a	chrII 6,911,299	asm-1 encodes a protein similar to human acid sphingomyelinase (ASM) or sphingomyelin phosphodiesterase; the ASM-1 protein has a putative secretory signal peptide at the N-terminus, saposin-like and proline-rich domains and putative N-linked glycosylation sites; asm-1 shows phosphodiesterase activity when expressed in COS-7 cells; while mammalian ASM is detected as both intracellular and secreted forms, asm-1 was detected exclusively in the secreted form; northern blot analysis indicates that asm-1 is expressed at higher levels in the embryo compared with other stages.
41	F44D12.7	F44D12.7	n/a	chrIV 10,035,774	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
42	kin-16	M176.7	n/a	chrII 9,435,019	kin-16 encodes a novel receptor protein tyrosine kinase; like kin-15, with which it is cotranscribed, kin-16 encodes a protein that displays some unusual features, including a very small extracellular domain (50 amino acids) that lacks a cysteine-rich region typical of ligand-binding domains of known receptor tyrosine kinases, an unusual amino acid substitution in the subdomain VI motif, and a lack of typical autophosphorylation sites in the kinase insert and C-terminal domains; a kin-16 reporter is first detected in young L1 larvae in the hyp7 syncytium; later expression is detected in ventral and lateral cells that fuse with hyp7 as well as in the more anterior hyp6 syncytium late in development; this distinct expression pattern suggests that kin-16 may also play a role in development of the hypodermal syncytium and perhaps be involved in cell-cell interactions regulating postembryonic cell fusions.
43	T10B11.4	T10B11.4	n/a	chrI 6,938,560
44	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
45	R12E2.8	R12E2.8	n/a	chrI 4,157,147	contains similarity to Galaxea fascicularis Galaxin.; TR:Q8I6S1
46	C06G4.4	C06G4.4	n/a	chrIII 7,977,442
47	pme-2	E02H1.4	n/a	chrII 9,594,003	pme-2 encodes a poly(ADP-ribose) polymerase (PARP) orthologous to human PARP2 (OMIM:607725); PME-2 has a predicted C-terminal catalytic domain; PME-2 has PARP activity in vitro, which is blocked by mammalian PARP inhibitors; since these inhibitors also cause embryonic lethality in worms exposed to ionizing radiation, PME-1 is likely to be required in vivo for repairing broken DNA.
48	T13F3.6	T13F3.6	n/a	chrV 16,270,691	contains similarity to Paramecium tetraurelia 51B type surface protein.; TR:Q27167
49	sre-50	C50E10.11	n/a	chrII 12,304,243	C. elegans SRE-50 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
50	nth-1	R10E4.5	n/a	chrIII 4,292,462	C. elegans NTH-1 protein; contains similarity to Pfam domains PF00633 (Helix-hairpin-helix motif) , PF00730 (HhH-GPD superfamily base excision DNA repair protein) contains similarity to Interpro domains IPR011257 (DNA glycosylase), IPR003651 (Iron-sulphur cluster loop), IPR000445 (Helix-hairpin-helix motif), IPR004035 (Endonuclease III, iron-sulphur binding, conserved site-1), IPR004036 (Endonuclease III, conserved site-2), IPR003265 (HhH-GPD)