UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	eat-4	ZK512.6	0	chrIII 9,139,280	eat-4 encodes an ortholog of the mammalian BNPI vesicular glutamate transporter that affects chemotaxis, feeding, foraging and thermotaxis; eat-4 is expressed in specific neurons, including M3L and M3R which are known to be glutamatergic.
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	F47F2.3	F47F2.3	n/a	chrX 3,894,817	contains similarity to Interpro domain IPR013032 (EGF-like region, conserved site)
4	F10E7.1	F10E7.1	n/a	chrII 7,127,780	contains similarity to Pfam domain PF06542 Protein of unknown function (DUF1114) contains similarity to Interpro domain IPR009497 (Protein of unknown function DUF1114)
5	B0563.7	B0563.7	n/a	chrX 9,153,274	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR001125 (Recoverin), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003299 (Flagellar calcium-binding protein (calflagin)), IPR000261 (EPS15 homology (EH))
6	adt-1	C02B4.1	n/a	chrX 12,683,974	The adt-1 gene encodes a metalloproteinase with disintegrin-like and metalloproteinase with thrombospondin type I motifs (ADAMTS) that is required for male tail morphogenesis.
7	gly-18	F22D6.11	n/a	chrI 7,111,262	GLY-18 is similar to 2/I N-acetylglucosaminyltransferase.
8	R07D5.2	R07D5.2	n/a	chrX 15,113,200	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR008979 (Galactose-binding like)
9	W05E10.2	W05E10.2	n/a	chrV 11,688,773	contains similarity to Homo sapiens Hypothetical protein; ENSEMBL:ENSP00000288462
10	ZK470.1	ZK470.1	n/a	chrX 4,166,695	contains similarity to Interpro domain IPR007248 (Mpv17/PMP22)
11	ZC84.3	ZC84.3	n/a	chrIII 9,188,742	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
12	C39B10.3	C39B10.3	n/a	chrX 10,443,924	contains similarity to Saccharomyces cerevisiae Protein involved in mating-type locus silencing, interacts with Sir2p; probably functions to recruit or stabilize Sir proteins; SGD:YDR363W
13	C55C3.2	C55C3.2	n/a	chrIV 5,707,741
14	nhr-251	ZK488.4	n/a	chrV 601,466	C. elegans NHR-251 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
15	C30B5.7	C30B5.7	n/a	chrII 6,225,999	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR003944 (Protease-activated receptor 4)
16	T01C8.4	T01C8.4	n/a	chrX 16,788,345	contains similarity to Pfam domain PF00155 Aminotransferase class I and II contains similarity to Interpro domains IPR004838 (Aminotransferases, class-I, pyridoxal-phosphate-binding site), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR004839 (Aminotransferase, class I and II), IPR000796 (Aspartate/other aminotransferase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
17	M05B5.6	M05B5.6	n/a	chrI 7,184,379	contains similarity to Homo sapiens Transient receptor potential cation channel subfamily A member 1; ENSEMBL:ENSP00000262209
18	T22B2.1	T22B2.1	n/a	chrX 3,927,779	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
19	nhr-90	ZK488.2	n/a	chrV 611,490	C. elegans NHR-90 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
20	F40G9.8	F40G9.8	n/a	chrIII 164,235
21	R07A4.4	R07A4.4	n/a	chrX 10,753,200	contains similarity to Pfam domain PF00024 PAN domain contains similarity to Interpro domains IPR000884 (Thrombospondin, type I), IPR003609 (Apple-like), IPR003014 (N/apple PAN), IPR008266 (Tyrosine protein kinase, active site)
22	C02B8.7	C02B8.7	n/a	chrX 8,137,743
23	nhr-44	T19A5.4	n/a	chrV 8,962,974	C. elegans NHR-44 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
24	T14C1.1	T14C1.1	n/a	chrX 14,408,600	T14C1.1 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that T14C1.1 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
25	gpa-10	C55H1.2	n/a	chrV 6,853,746	gpa-10 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADF, ASI, ASJ, ALN, CAN, LUA, and the spermatheca.
26	ubc-22	C06E2.7	n/a	chrX 8,868,414	ubc-22 encodes an E2 ubiquitin-conjugating enzyme orthologous to Saccharomyces cerevisiae UBC8 and human UBC1/HIP2 (Huntingtin interacting protein 2, OMIM:602846) which are involved in regulating fructose-1,6-bisphosphatase and huntingtin catabolism, respectively; by homology, UBC-22 is likely required for covalent attachment of ubiquitin to select target proteins to facilitate their degradation; however, as loss of UBC-22 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UBC-22 in C. elegans development and/or behavior is not yet known.
27	T05E11.8	T05E11.8	n/a	chrIV 11,105,287	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
28	F56C3.9	F56C3.9	n/a	chrX 1,392,907	contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR013089 (Kelch related)
29	lgc-37	ZC482.5	n/a	chrIII 12,789,021	ZC482.5 is orthologous to the human gene GAMMA-AMINOBUTYRIC ACID A RECEPTOR GAMMA 2 (GABRG2; OMIM:137164), which when mutated leads to disease.
30	srh-179	ZK228.7	n/a	chrV 18,477,190	C. elegans SRH-179 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
31	F14H8.2	F14H8.2	n/a	chrV 15,019,750	contains similarity to Sulfolobus solfataricus Heterodisulfite reductase, subunit B (hdrB-1).; TR:Q97Z15
32	ast-1	T08H4.3	n/a	chrII 4,131,358	ast-1 encodes a novel ETS-box transcription factor; AST-1 is required for the proper navigation of some interneuron axons to their targets, for differentiation of the ventral cord pioneer neuron AVG, and for pharyngeal morphogenesis; AST-1 is transiently expressed in many head neurons late in their differentiation and axon outgrowth, and in a few pharyngeal cells; AST-1 is at first nuclear, but then relocates to spots in cell bodies and even neuronal processes; hypomorphic ast-1 mutants have axons extending laterally, and crossing over from the right axon tract to the left axon bundle; null ast-1(hd92) mutants are inviable, failing to attach a working pharynx to their cuticle during development and then starving as L1 larvae; behaviorally, hypomorphic ast-1 animals are at least superficially normal, indicating that the ventral nerve cord can tolerate at least some miswiring; AST-1 regulates odr-2 expression, while ast-1 expression is itself regulated by lin-11.
33	clec-202	C30H6.4	n/a	chrIV 17,362,968	C. elegans CLEC-202 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
34	ZK816.1	ZK816.1	n/a	chrX 3,359,733
35	cut-5	R07E3.3	n/a	chrX 10,336,033	C. elegans CUT-5 protein; contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
36	mec-4	T01C8.7	n/a	chrX 16,805,158	mec-4 encodes an amiloride-sensitive Na+ channel protein (degenerin) required to sense gentle mechanical stimuli (e.g. touch) along the body wall; MEC-4 is paralogous to, and coexpressed with, MEC-10, in all six touch cell neurons where they form a heteromeric mechanotransduction channel.
37	F18A11.5	F18A11.5	n/a	chrII 13,010,794	contains similarity to Pfam domains PF02214 (K+ channel tetramerisation domain) , PF03931 (Skp1 family, tetramerisation domain) contains similarity to Interpro domains IPR001232 (SKP1 component), IPR016072 (SKP1 component, dimerisation), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation), IPR016073 (SKP1 component, POZ)
38	M03C11.6	M03C11.6	n/a	chrIII 10,422,780	contains similarity to Brachydanio rerio SI:bZ1G13.2 (ORF1 of novel LINE element with similarities to gagsproteins ).; TR:Q804R5
39	C45E5.4	C45E5.4	n/a	chrIV 5,736,046
40	odr-3	C34D1.3	n/a	chrV 13,248,189	odr-3 encodes a G protein alpha subunit; odr-3 activity is required for normal chemotaxis, odorant avoidance, and nociceptive function as well as cilium morphogenesis in chemosensory neurons; an ODR-3::GFP is expressed in five pairs of sensory neurons AWA, AWB, AWC, ASH, and ADF; the AWC neurons consistently express GFP most strongly, while the AWB neurons express at lower levels and the AWA, ASH, and ADF neurons express only weakly; in AWC neurons, ODR-3::GFP localizes to cilia which have a characteristic wing-shaped morphology.
41	sru-36	R07B5.6	n/a	chrV 9,842,407	C. elegans SRU-36 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
42	F37C12.1	F37C12.1	n/a	chrIII 7,186,028	contains similarity to Pfam domain PF04502 Family of unknown function (DUF572) contains similarity to Interpro domain IPR007590 (Protein of unknown function DUF572)
43	C38C3.6	C38C3.6	n/a	chrV 1,485,347	contains similarity to Interpro domain IPR000694 (Proline-rich region)
44	C38H2.2	C38H2.2	n/a	chrIII 10,383,431	C38H2.2 encodes a core 1 UDP-Gal:GalNAcalpha1-Ser/Thr beta1,3-galactosyltransferase (core 1 beta3-Gal-T or T-synthase, EC2.4.1.122); C38H2.2 protein is predicted to be primarily extracellular, with an N-terminal transmembrane domain; C38H2.2 shares 6 conserved cysteine residues with all known T-synthases, and is ubiquitously expressed; enzymatically active C38H2.2 can be generated from insect but not mammalian cells, suggesting that invertebrate-specific chaperones are required for its activity.
45	T22D1.2	T22D1.2	n/a	chrIV 6,922,337	contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR000694 (Proline-rich region), IPR000480 (Glutelin), IPR013286 (Annexin, type VII)
46	T20D4.5	T20D4.5	n/a	chrV 3,414,578	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
47	ZK455.5	ZK455.5	n/a	chrX 11,325,637	contains similarity to Pfam domain PF01066 CDP-alcohol phosphatidyltransferase contains similarity to Interpro domains IPR014472 (Choline/ethanolaminephosphotransferase), IPR000462 (CDP-alcohol phosphatidyltransferase)
48	R09D1.5	R09D1.5	n/a	chrII 9,448,892	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
49	srx-136	F09F3.12	n/a	chrV 13,858,174	C. elegans SRX-136 protein ;
50	F35E2.1	F35E2.1	n/a	chrI 11,739,734	contains similarity to Pfam domain PF06681 Protein of unknown function (DUF1182) contains similarity to Interpro domains IPR002091 (Aromatic amino acid permease), IPR010601 (Protein of unknown function DUF1182)