UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	sod-5	ZK430.3	1e-92	chrII 4,418,355	C. elegans SOD-5 protein; contains similarity to Pfam domain PF00080 Copper/zinc superoxide dismutase (SODC) contains similarity to Interpro domain IPR001424 (Superoxide dismutase, copper/zinc binding)
2	twk-20	C40C9.1	n/a	chrX 13,640,987	C. elegans TWK-20 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR013521 (Potassium channel, inwardly rectifying, Kir, conserved region 2), IPR003280 (Potassium channel, two pore-domain), IPR003938 (Potassium channel, voltage-dependent, EAG/ELK/ERG), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
3	mec-10	F16F9.5	n/a	chrX 8,467,984	The mec-10 gene encodes an amiloride-sensitive Na+ channel protein (degenerin) required to sense gentle mechanical stimuli (e.g. touch) along the body wall; it is paralogous to mec-4, which has similar function in vivo.
4	F02D10.3	F02D10.3	n/a	chrX 13,461,339	contains similarity to Escherichia coli;Escherichia coli O6;Escherichia coli O157:H7 Hypothetical protein yeaG.; SW:YEAG_ECOLI
5	coq-1	C24A11.9	n/a	chrI 5,414,239	coq-1 encodes a putative hexaprenyl pyrophosphate synthetase, orthologous to S. cerevisiae COQ1; COQ-1 is required for ubiquinone (coenzyme Q9) biosynthesis and for normally short lifespan; coq-1 mutants have slowed pharyngeal pumping, and eventually arrest as paralysed larvae before dying; coq-1(RNAi) animals have reduced levels of coenzyme Q9 and superoxide, and have abnormally long lifespans; coq-1 mutants are not rescued by dietary coenzyme Q.
6	T26G10.3	T26G10.3	n/a	chrIII 9,413,048	contains similarity to Pfam domain PF01282 Ribosomal protein S24e contains similarity to Interpro domain IPR001976 (Ribosomal protein S24e)
7	srt-27	C24B9.6	n/a	chrV 2,720,278	C. elegans SRT-27 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
8	W02D9.8	W02D9.8	n/a	chrI 12,558,734	contains similarity to Interpro domain IPR004692 (Preprotein translocase SecG subunit)
9	rom-3	Y116A8C.14	n/a	chrIV 16,967,844	C. elegans ROM-3 protein; contains similarity to Pfam domain PF01694 Rhomboid family contains similarity to Interpro domain IPR002610 (Peptidase S54, rhomboid)
10	Y7A5A.2	Y7A5A.2	n/a	chrX 15,772,148	contains similarity to Aquifex aeolicus Hypothetical protein AQ_372.; SW:Y372_AQUAE
11	ZK380.2	ZK380.2	n/a	chrX 1,633,167	contains similarity to Interpro domain IPR011072 (HR1 rho-binding repeat)
12	F39F10.2	F39F10.2	n/a	chrX 16,895,317	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
13	Y50F7A.2	Y50F7A.2	n/a	chrII 1,183,626
14	acr-11	D2092.3	n/a	chrI 6,623,291	A homolog of an alpha type nicotinic acetylcholine receptor subunit involved in the mediation of fast synaptic transmission at neuromuscular junctions.
15	F20H11.6	F20H11.6	n/a	chrIII 6,599,869
16	F57E7.1	F57E7.1	n/a	chrV 16,481,775	contains similarity to Bos taurus Enoyl-CoA hydratase precursor (EC 4.2.1.17) (Fragment).; TR:Q95KZ6
17	T06D4.2	T06D4.2	n/a	chrII 3,385,081
18	T05B4.10	T05B4.10	n/a	chrV 4,120,294	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
19	K03B8.8	K03B8.8	n/a	chrV 11,410,221	contains similarity to Interpro domains IPR006030 (Molluscan rhodopsin C-terminal tail), IPR000694 (Proline-rich region)
20	srh-112	T19C9.2	n/a	chrV 17,225,620	C. elegans SRH-112 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	srj-22	F28H7.1	n/a	chrV 10,743,082	C. elegans SRJ-22 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	C50H11.17	C50H11.17	n/a	chrV 3,097,908	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
23	C18G1.8	C18G1.8	n/a	chrV 4,765,470	contains similarity to Pfam domain PF01531 Glycosyl transferase family 11 contains similarity to Interpro domain IPR002516 (Glycosyl transferase, family 11)
24	F36A2.2	F36A2.2	n/a	chrI 8,803,215	contains similarity to Pfam domain PF01207 Dihydrouridine synthase (Dus) contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001269 (Dihydrouridine synthase, DuS)
25	F44G3.10	F44G3.10	n/a	chrV 16,139,209	F44G3.10 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; F44G3.10 is worm-specific, with obvious homologs only in C. elegans; F44G3.10 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
26	T05A7.9	T05A7.9	n/a	chrII 4,684,669	contains similarity to Pfam domain PF01744 GLTT repeat (6 copies) contains similarity to Interpro domain IPR008164 (Repeat of unknown function XGLTT)
27	nrd-1	D1007.7	n/a	chrI 4,600,304	C. elegans NRD-1 protein; contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR006569 (Regulation of nuclear pre-mRNA protein), IPR000694 (Proline-rich region), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR008942 (ENTH/VHS), IPR000504 (RNA recognition motif, RNP-1)
28	str-257	C01B4.1	n/a	chrV 2,519,650	C. elegans STR-257 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
29	T24C12.1	T24C12.1	n/a	chrX 2,200,143	contains similarity to Interpro domain IPR008952 (Tetraspanin)
30	F41E6.8	F41E6.8	n/a	chrV 8,600,475	contains similarity to Pfam domain PF03380 Caenorhabditis protein of unknown function, DUF282 contains similarity to Interpro domain IPR005044 (Protein of unknown function DUF282, Caenorhabditis species)
31	H42K12.2	H42K12.2	n/a	chrX 1,319,512
32	rrf-3	F10B5.7	n/a	chrII 8,165,532	rrf-3 encodes an RNA-directed RNA polymerase (RdRP) homolog that inhibits somatic RNAi, and thus promotes activity of repeated genes (e.g., multicopy transgenic arrays); the effect of RRF-3 on RNAi is opposite to that of RRF-1 (which stimulates somatic RNAi), which might arise from competition by RRF-3 with RRF-1 or EGO-1 in RNAi formation; rrf-3(allele) or rrf-3(allele2) mutants are hypersensitive to somatic RNAi, and conversely suppress the activity of an integrated rol6 (su1006) transgene.
33	hlh-29	F31A3.4	n/a	chrX 17,548,141	C. elegans HLH-29 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
34	gcy-23	T26C12.4	n/a	chrIV 3,286,107	gcy-23 encodes a receptor-type guanylyl cyclase that, along with gcy-8 and gcy-18, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-23 functions redundantly with gcy-8 and gcy-18, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; in addition, loss of gcy-23 activity via RNAi results in lifespan extension; GCY-23 is expressed exclusively in the AFD thermosensory neurons, where it localizes to sensory endings.
35	srh-48	C06C3.6	n/a	chrII 9,384,056	C. elegans SRH-48 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
36	lgc-40	T24D8.1	n/a	chrX 2,362,451	C. elegans LGC-40 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
37	str-74	C14H10.4	n/a	chrX 10,240,354	C. elegans STR-74 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
38	W02D9.9	W02D9.9	n/a	chrI 12,557,310	contains similarity to Bacteroides thetaiotaomicron Arabinose-proton symporter (Arabinose transporter).; TR:Q8AAL0
39	C52B9.8	C52B9.8	n/a	chrX 4,300,505	contains similarity to Pfam domains PF00271 (Helicase conserved C-terminal domain) , PF07529 (HSA) , PF04851 (Type III restriction enzyme, res subunit) , PF00176 (SNF2 family N-terminal domain) contains similarity to Interpro domains IPR006935 (Restriction endonuclease, type I, R subunit/Type III, Res subunit), IPR013999 (HAS subgroup), IPR014012 (Helicase/SANT-associated, DNA binding), IPR000330 (SNF2-related), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR006562 (HSA), IPR005448 (Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
40	srh-71	T10D4.5	n/a	chrII 3,124,197	C. elegans SRH-71 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	dylt-3	T05C12.5	n/a	chrII 8,181,777	dylt-3 encodes a putative dynein light chain subunit paralogous to DYLT-3, and orthologous to human DYNLT1 and DYNLT3 (OMIM: 300302); unlike its paralog DYLT-1, DYLT-3 does not obviously inhibit DHC-1 in vivo.
42	Y54E2A.2	Y54E2A.2	n/a	chrII 14,750,101	contains similarity to Interpro domain IPR003593 (AAA+ ATPase, core)
43	Y49F6C.7	Y49F6C.7	n/a	chrII 3,367,722
44	M70.5	M70.5	n/a	chrIV 2,270,286	contains similarity to Pfam domain PF01436 NHL repeat contains similarity to Interpro domains IPR011042 (Six-bladed beta-propeller, TolB-like), IPR001258 (NHL repeat)
45	Y102E9.3	Y102E9.3	n/a	chrIII 6,734,194
46	C26B2.5	C26B2.5	n/a	chrIV 8,040,889
47	srh-298	Y94A7B.5	n/a	chrV 17,819,902	C. elegans SRH-298 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
48	F35F10.14	F35F10.14	n/a	chrV 3,319,580
49	C37C3.7	C37C3.7	n/a	chrV 7,836,124	contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR013032 (EGF-like region, conserved site)
50	K04G11.4	K04G11.4	n/a	chrX 14,351,065	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR000694 (Proline-rich region), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR001632 (G-protein, beta subunit), IPR015943 (WD40/YVTN repeat-like)