UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	clec-97	ZK39.6	1.0000000000000001e-106	chrI 11,153,502	C. elegans CLEC-97 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
2	grl-17	C56A3.1	n/a	chrV 13,562,991	grl-17 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-17 is expressed in pharynx, rectal epithelium, amphid socket cells, larval arcade cells, and larval hypodermis; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
3	F57F4.2	F57F4.2	n/a	chrV 6,388,125	contains similarity to Felis silvestris catus RPGR (Fragment).; TR:Q56PC0
4	col-116	F17E9.1	n/a	chrIV 8,357,297	C. elegans COL-116 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
5	ins-23	M04D8.3	n/a	chrIII 10,028,305	ins-23 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-23 is one of 38 insulin-like peptides in C. elegans, and is expressed in amphid sensory neurons, labial neurons, the nerve ring, and ventral nerve cord neurons; as loss of INS-23 function via RNA-mediated interference does not results in any abnormalities, the precise role of INS-23 in C. elegans development is not yet clear.
6	C06G3.3	C06G3.3	n/a	chrIV 7,036,272
7	hsp-12.3	F38E11.1	n/a	chrIV 9,445,065	hsp-12.3 encodes a small heat-shock protein that forms heterotetramers with HSP-12.2 and has no chaperone-like activity; structurally, HSP-12.3 is mostly a beta-sheet; at least one HSP-12 (which may or may not be HSP-12.2) is ubiquitously expressed in L1 larvae, and later expressed in adult spermatids (and perhaps spermatocytes), and some adult vulval cells; hsp-12.3 is upregulated in daf-2 mutants, suggesting that hsp-12.3's expression may contribute to prolonged lifespan in dauer larvae.
8	F43H9.4	F43H9.4	n/a	chrV 8,027,713	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
9	clec-98	ZK39.7	1.9999999999999998e-30	chrI 11,154,783	C. elegans CLEC-98 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
10	nlp-32	F30H5.2	n/a	chrIII 486,349	C. elegans NLP-32 protein; contains similarity to Interpro domain IPR002952 (Eggshell protein)
11	B0507.8	B0507.8	n/a	chrV 8,761,695	contains similarity to Schizosaccharomyces pombe Nucleoporin nup211 (Nuclear pore protein nup211).; SW:O74424
12	F48G7.2	F48G7.2	n/a	chrV 637,034
13	C35C5.9	C35C5.9	n/a	chrX 11,536,770	contains similarity to Haemophilus influenzae Monofunctional biosynthetic peptidoglycan transglycosylases(EC 2.4.2.-) (Monofunctional TGase).; SW:MTGA_HAEIN
14	C13A2.3	C13A2.3	n/a	chrV 7,283,523	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
15	F56H9.2	F56H9.2	n/a	chrV 12,637,872	contains similarity to Plasmodium falciparum Transport protein, putative.; TR:Q8IHR3
16	F11F1.6	F11F1.6	n/a	chrIII 13,403,684	contains similarity to Escherichia coli Shiga toxin 1 B subunit.; TR:Q8L167
17	col-102	C18H7.3	n/a	chrIV 605,160	col-102 encodes a cuticle collagen.
18	T01C3.4	T01C3.4	n/a	chrV 14,994,531	contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
19	cex-1	F56D1.6	n/a	chrII 5,448,034	C. elegans CEX-1 protein; contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
20	col-35	C15A11.1	n/a	chrI 7,386,359	col-35 encodes a collagen that is individually dispensable for viability and gross morphology in mass RNAi screens; the amino- and carboxyl-terminal cysteine-rich regions of COL-35 are most closely related to those of COL-8, COL-19, and COL-39.
21	srh-193	F47D2.9	n/a	chrV 4,289,288	C. elegans SRH-193 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	grl-19	R02D3.6	n/a	chrIV 252,252	grl-19 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-19 is expressed in intestine; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
23	F49H6.5	F49H6.5	n/a	chrV 17,024,380	The F49H6.5 gene encodes a homolog of the human gene MOCS1A, which when mutated leads to molybdenum cofactor deficiency (OMIM:252150).
24	F07C4.6	F07C4.6	n/a	chrV 7,627,266	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
25	ttr-2	K03H1.4	n/a	chrIII 9,928,259	K03H1.4 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; the product of K03H1.4 belongs to a family of apparently nematode-specific proteins whose function is not yet known.
26	C32F10.4	C32F10.4	n/a	chrI 5,809,249
27	F47B8.8	F47B8.8	n/a	chrV 14,332,167	contains similarity to Pfam domain PF01433 Peptidase family M1 contains similarity to Interpro domain IPR014782 (Peptidase M1, membrane alanine aminopeptidase, N-terminal)
28	ttr-5	C40H1.5	n/a	chrIII 9,330,525	C40H1.5 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; the product of C40H1.5 belongs to a family of apparently nematode-specific proteins whose function is not yet known.
29	C03G6.6	C03G6.6	n/a	chrV 7,358,148	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
30	scl-2	F49E11.10	n/a	chrIV 13,058,350	C. elegans SCL-2 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
31	F40G12.5	F40G12.5	n/a	chrV 14,269,931	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
32	B0284.1	B0284.1	n/a	chrIII 4,377,822	contains similarity to Interpro domain IPR016027 (Nucleic acid-binding, OB-fold-like)
33	nlp-39	C54C8.9	n/a	chrI 12,461,774	C. elegans NLP-39 protein ;
34	nlp-29	B0213.4	n/a	chrV 3,984,616	nlp-29 encodes a neuropeptide-like protein; nlp-29 appears to play a role in innate immunity, as its expression is strongly induced following bacterial and fungal infection; nlp-29 is expressed in the hypodermis and in the intestine; nlp-29 expression is regulated by TIR-1, an ortholog of SARM, a Toll-interleukin 1 receptor (TIR) domain protein, and by the RAB-1 GTPase and the product of R53.4, a mitochondrial ATP synthase subunit f homolog.
35	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
36	ZC196.2	ZC196.2	n/a	chrV 8,740,693	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
37	col-2	W01B6.7	n/a	chrIV 10,084,918	col-2 encodes a member of the collagen superfamily containing collagen triple helix repeats (20 copies); expression peaks during the molt that separates the L2 larval and dauer stages as the dauer cuticle is being formed, and mRNA is expressed at low levels in post-dauer L4 larvae and in adult animals.
38	cpr-2	F36D3.9	n/a	chrV 16,533,516	C. elegans CPR-2 protein; contains similarity to Pfam domain PF00112 Papain family cysteine protease contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR000668 (Peptidase C1A, papain C-terminal)
39	W03F11.1	W03F11.1	n/a	chrI 2,220,892	W03F11.1 encodes a protein with three chitin-binding peritrophin-A domains; like CEJ-1 and CPG-2, W03F11.1 may participate in eggshell synthesis and early embryonic development; W03F11.1 is required for fertility in mass RNAi assays; W03F11.1's multiple peritrophin-A domains might enable mechanical cross-linking of chitin.
40	ncx-9	C13D9.8	n/a	chrV 4,993,269	ncx-9 encodes a putative Na[+]/Ca[2+] exchanger of uncertain stoichiometry and affinity, orthologous to human SLC24A6 and paralogous to NCX-6/-8 and NCX-10; NCX-9 may function intracellularly; NCX-9 has tandem Calx-alpha domains predicted to carry out ion transport; NCX-9 has no obvious function in mass RNAi assays.
41	nas-20	T11F9.3	n/a	chrV 11,471,595	nas-20 encodes an astacin-like metalloprotease.
42	T19D12.3	T19D12.3	n/a	chrII 6,660,581
43	str-182	C12D8.12	n/a	chrV 10,232,595	C. elegans STR-182 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	nlp-28	B0213.3	n/a	chrV 3,988,091	C. elegans NLP-28 protein ; contains similarity to Ixodes scapularis Putative secreted salivary gland peptide.; TR:Q5Q982
45	fbxa-162	C08E3.5	n/a	chrII 1,608,500	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
46	C06E4.8	C06E4.8	n/a	chrIV 7,284,853	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
47	grd-4	T01B10.1	n/a	chrX 8,501,684	grd-4 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground domain; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-4 is weakly required for normal molting; GRD-4 is also required for normal adult alae formation, growth to full size, and locomotion; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
48	F22B7.9	F22B7.9	n/a	chrIII 8,653,148
49	F32G8.3	F32G8.3	n/a	chrV 10,554,899	contains similarity to Homo sapiens Splice isoform Long of Q13595 Transformer-2 protein homolog; ENSEMBL:ENSP00000297071
50	F09F7.6	F09F7.6	n/a	chrIII 5,551,674