UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZK353.2	ZK353.2	9e-25	chrIII 8,398,849	contains similarity to Interpro domain IPR002952 (Eggshell protein)
2	C44B12.6	C44B12.6	n/a	chrIV 1,131,250	contains similarity to Interpro domain IPR010345 (Interleukin-17)
3	Y65A5A.1	Y65A5A.1	n/a	chrIV 16,399,303	contains similarity to Interpro domain IPR001092 (Basic helix-loop-helix dimerization domain bHLH)
4	sqv-8	ZK1307.5	n/a	chrII 9,648,550	The sqv-8 gene encodes a glucuronyl transferase, biochemically active in vitro, that is required for cytokinesis of one-cell embryos and for vulval morphogenesis; SQV-8 is homologous to three distinct glucuronyl transferases (GlcAT-I, GlcAT-P and GlcAT-D) that play a role in the synthesis of different glycoconjugates; the common requirement for SQV-8 in both cytokinesis and morphogenesis may be to promote filling an extracellular space with hygroscopic proteoglycans (either in the eggshell, or underneath the L4 cuticle), which in turn may cause the space to fill with fluid.
5	gcy-4	ZK970.5	n/a	chrII 10,306,418	gcy-4 encodes a predicted transmembrane guanylyl cyclase; by homology, GCY-4 may function as a chemosensory receptor; however, as loss of gcy-4 activity via mutation or large-scale RNAi screens results in no obvious abnormalities, the precise role of gcy-4 in C. elegans development and/or behavior is not yet known; the sole gcy-4 ::GFP reporter construct reported to date did not produce any specific GFP signals.
6	srd-25	F07C4.4	n/a	chrV 7,632,583	C. elegans SRD-25 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
7	F01F1.14	F01F1.14	n/a	chrIII 5,882,603
8	Y38H8A.5	Y38H8A.5	n/a	chrIV 13,467,731	The Y38H8A.5 gene encodes a homolog of the human gene ZNF195 (or p57KIP2), which when mutated leads to Beckwith-Wiedemann syndrome (OMIM:130650).
9	sri-77	D2062.9	n/a	chrII 2,604,314	C. elegans SRI-77 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
10	F33C8.2	F33C8.2	n/a	chrX 14,722,337	contains similarity to Interpro domain IPR003382 (Flavoprotein)
11	gpa-13	F18E2.5	n/a	chrV 12,753,806	gpa-13 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADF, ASH, AWC, PHA, and PHB.
12	F46B3.15	F46B3.15	n/a	chrV 20,628,725	contains similarity to Interpro domain IPR003645 (Follistatin-like, N-terminal)
13	str-256	T01G6.9	n/a	chrV 500,551	C. elegans STR-256 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
14	F59B10.2	F59B10.2	n/a	chrII 10,508,511	contains similarity to Interpro domains IPR003993 (Treacher Collins syndrome, treacle), IPR005819 (Histone H5)
15	uev-3	F26H9.7	n/a	chrI 9,311,457	uev-3 encodes a ubiquitin-conjugating enzyme (UBC or E2) variant that contains the UBC motif, but lacks the critical active-site cysteine residue necessary for catalytic activity; as loss of UEV-3 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UEV-3 in C. elegans development and/or behavior is not yet known; based on similarity to Saccharomyces cerevisiae and human proteins, however, UEV-3 may play a role in cell cycle control or response to stress or DNA damage.
16	sre-33	W05H5.6	n/a	chrII 12,453,974	C. elegans SRE-33 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
17	EGAP2.2	EGAP2.2	n/a	chrII 5,230,269
18	B0302.4	B0302.4	n/a	chrX 17,176,549
19	R11G11.3	R11G11.3	n/a	chrV 531,412	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
20	F21C10.6	F21C10.6	n/a	chrV 9,124,712	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
21	srsx-1	F40D4.5	n/a	chrV 17,177,360	C. elegans SRSX-1 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
22	R09H3.1	R09H3.1	n/a	chrX 1,660,650	contains similarity to Sulfolobus solfataricus DNA double-strand break repair rad50 ATPase.; SW:Q97WH0
23	str-225	C07G3.6	n/a	chrV 3,508,534	C. elegans STR-225 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001307 (Thiosulphate sulphurtransferase, conserved site)
24	sdz-34	Y73C8C.7	n/a	chrV 3,108,727	C. elegans SDZ-34 protein; contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000533 (Tropomyosin), IPR011016 (Zinc finger, variant RING-type)
25	srh-283	C47A10.2	n/a	chrV 17,766,031	C. elegans SRH-283 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
26	R04B5.7	R04B5.7	n/a	chrV 10,089,830	contains similarity to Rattus norvegicus Protein tyrosine phosphatase TD14.; TR:O88902
27	F31B9.1	F31B9.1	n/a	chrX 15,912,318	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002286 (P2 purinoceptor), IPR006121 (Heavy metal transport/detoxification protein), IPR000276 (GPCR, rhodopsin-like)
28	srj-29	F22B8.1	n/a	chrV 16,076,456	C. elegans SRJ-29 protein; contains similarity to Pfam domains PF00060 (Ligand-gated ion channel) , PF01094 (Receptor family ligand binding region) contains similarity to Interpro domains IPR001638 (Bacterial extracellular solute-binding protein, family 3), IPR015683 (Glutamate receptor-related), IPR001320 (Ionotropic glutamate receptor), IPR001828 (Extracellular ligand-binding receptor), IPR001508 (NMDA receptor)
29	srx-39	C03A7.6	n/a	chrV 5,157,191	C. elegans SRX-39 protein; contains similarity to Pfam domains PF00001 (7 transmembrane receptor (rhodopsin family)) , PF01748 (Caenorhabditis serpentine receptor-like protein) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR013305 (ABC transporter, ABCB2), IPR000276 (GPCR, rhodopsin-like)
30	wrn-1	F18C5.2	n/a	chrII 6,557,068	wrn-1 encodes an ortholog of human WRN, which when mutated leads to Werner syndrome (OMIM:277700), and one of four C. elegans homologs of the RecQ DNA helicase family that includes E. coli RecQ; by homology, WRN-1 is predicted to function as a helicase, DNA-dependent ATPase, and exonuclease that plays a key role in DNA replication, recombination, and repair; RNA interference studies in C. elegans and the enhancement of many of the resulting phenotypes by ionizing radiation indicate that wrn-1 affects life span and aging and acts at a DNA damage checkpoint; the wrn-1 phenotypes such as premature aging are similar to those of Werner syndrome; immunolocalization studies indicate that WRN-1 expression is nuclear in cells at the embryonic, larval and adult stages.
31	C54G10.1	C54G10.1	n/a	chrV 14,641,219	contains similarity to Homo sapiens similar to secreted gel-forming mucin; ENSEMBL:ENSP00000328427
32	C32B5.14	C32B5.14	n/a	chrII 966,320
33	bath-45	F29C12.5	n/a	chrII 13,123,821	C. elegans BATH-45 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) (2), PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
34	ZC190.9	ZC190.9	n/a	chrV 8,692,862
35	C39D10.1	C39D10.1	n/a	chrX 7,906,986
36	ztf-9	ZK287.6	n/a	chrV 9,691,558	C. elegans ZTF-9 protein; contains similarity to Interpro domain IPR015880 (Zinc finger, C2H2-like)
37	C07A9.12	C07A9.12	n/a	chrIII 9,726,313	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
38	F07H5.7	F07H5.7	n/a	chrII 8,793,642
39	F22E12.3	F22E12.3	n/a	chrV 10,461,278	contains similarity to Petroselinum crispum Reverse transcriptase (Fragment).; TR:Q9ZRL1
40	srd-56	E04F6.14	n/a	chrII 7,202,553	C. elegans SRD-56 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	F55G7.3	F55G7.3	n/a	chrX 11,941,116	contains similarity to Saccharomyces cerevisiae appears to control expression of spliceosome components PRP4 and PRP3; SGD:YDR464W
42	ZC190.10	ZC190.10	n/a	chrV 8,696,074
43	fbxa-113	Y113G7B.6	n/a	chrV 20,199,350	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
44	C50F7.6	C50F7.6	n/a	chrIV 7,721,871	contains similarity to Homo sapiens Isoform 4 of PDZ domain-containing RING finger protein 4; ENSEMBL:ENSP00000370169
45	str-23	C55A1.5	n/a	chrV 15,645,650	C. elegans STR-23 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
46	F55E10.5	F55E10.5	n/a	chrX 8,335,538
47	T14G8.2	T14G8.2	n/a	chrX 12,858,701	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
48	F56E10.3	F56E10.3	n/a	chrV 82,911	contains similarity to Pfam domain PF06371 Diaphanous GTPase-binding Domain contains similarity to Interpro domain IPR010473 (Diaphanous GTPase-binding)
49	srw-12	C41G6.2	n/a	chrV 15,237,968	C. elegans SRW-12 protein ;
50	srj-45	T03D3.6	n/a	chrV 2,836,005	C. elegans SRJ-45 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR006162 (Phosphopantetheine attachment site)