UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ceh-8	ZK265.4	8e-139	chrI 8,248,368	ceh-8 encodes a paired-like homeodomain protein of the Q50 class orthologous to the Rx homeobox protein of humans (RAX; OMIM:601881) and Drosophila (CG10052-PA); CEH-8 and RX belong to one of at least 18 distinct families of paired-like homeodomain proteins, including 12 families in the Q50 class.
2	srv-1	R13F6.3	n/a	chrIII 6,852,129	C. elegans SRV-1 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
3	VC27A7L.1	VC27A7L.1	n/a	chrV 12,165,914	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
4	srv-32	T13A10.12	n/a	chrIV 6,281,179	C. elegans SRV-32 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000366 (Fungal pheromone mating factor STE2 GPCR)
5	B0304.2	B0304.2	n/a	chrII 4,524,073
6	gmn-1	Y75B8A.17	n/a	chrIII 12,224,862	C. elegans GMN-1 protein ;
7	C04E7.3	C04E7.3	n/a	chrX 345,208	contains similarity to Homo sapiens inner centromere protein antigens 135/155kDa isoform 2; ENSEMBL:ENSP00000278849
8	srx-113	F56H9.1	n/a	chrV 12,631,137	C. elegans SRX-113 protein ;
9	F21F8.2	F21F8.2	n/a	chrV 8,275,167	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001461 (Peptidase A1)
10	mex-5	W02A2.7	n/a	chrIV 13,354,881	mex-5 encodes a novel protein that contains two CCCH zinc finger motifs; maternally provided MEX-5, which functions partly redundantly with the highly similar CCCH finger protein MEX-6, is essential for transducing polarity cues and establishing soma/germline asymmetry in the early embryo; in regulating soma/germline asymmetry, MEX-5 interacts with, and activates, the SOCS-box protein ZIF-1, which functions as part of an E3 ubiquitin ligase complex that degrades germ plasm proteins in somatic blastomeres; accordingly, ectopic expression of MEX-5 throughout the early embryo results in reduced expression of germline proteins in germline blastomeres; MEX-5 is a cytoplasmic protein expressed at uniform levels in oocytes and newly fertilized eggs; from the 1-cell to 4-cell stages of embryogenesis, MEX-5 expression is dynamic, with highest levels seen in the anterior AB blastomere and, for a time, its daughters, the anterior portion of the P1 blastomere, P1 centrosomes (both, then posterior only), and the EMS and C blastomeres; the asymmetric distribution of MEX-5 in early embryos depends upon wild-type activity of the PAR and OMA-1 proteins.
11	R07B7.6	R07B7.6	n/a	chrV 12,073,908	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)
12	inx-16	R12E2.5	n/a	chrI 4,163,537	inx-16 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; as loss of INX-16 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of INX-16 in C. elegans development and/or behavior is not yet known; the INX-16 expression pattern has not been determined.
13	C31H5.6	C31H5.6	n/a	chrI 9,045,096	contains similarity to Pfam domains PF08840 (BAAT / Acyl-CoA thioester hydrolase C terminal) , PF04775 (Acyl-CoA thioester hydrolase / Bile acid-CoA amino acid N-acetyltransferase) contains similarity to Interpro domains IPR006862 (Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase), IPR014940 (BAAT/Acyl-CoA thioester hydrolase C-terminal), IPR016662 (Acyl-CoA thioesterase, long chain)
14	C26B2.7	C26B2.7	n/a	chrIV 8,016,527
15	pap-1	Y32F6A.3	n/a	chrV 10,444,197	pap-1 encodes a poly (A) polymerase; large-scale RNAi screens indicate that PAP-1 activity is essential for reproduction, embryonic and larval development, proper body morphology, normal rates of growth, and coordinated locomotion.
16	vps-16	C05D11.2	n/a	chrIII 6,434,734	vps-16 encodes the C. elegans homolog of the Saccharomyces cerevisiae vacuolar sorting protein Vps16p; in C. elegans, vps-16 activity is required for biogenesis of the lysosome-related gut granules and for embryonic development; in addition, vps-16 is required for normal body morphology and regulation of germline apoptosis.
17	F33H1.4	F33H1.4	n/a	chrII 10,177,309	contains similarity to Pfam domain PF02178 (AT hook motif)
18	T25C8.1	T25C8.1	n/a	chrIII 13,611,268	contains similarity to Interpro domains IPR002345 (Lipocalin), IPR000577 (Carbohydrate kinase, FGGY)
19	ugt-32	F47C10.6	n/a	chrV 3,842,918	C. elegans UGT-32 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
20	C50H2.4	C50H2.4	n/a	chrV 9,917,432	contains similarity to Arabidopsis thaliana Putative cytochrome P450.; TR:Q9LQ26
21	D1022.5	D1022.5	n/a	chrII 7,458,058
22	C46A5.6	C46A5.6	n/a	chrIV 7,761,969
23	pqn-73	W01C9.3	n/a	chrII 8,543,297	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
24	str-262	C05E4.13	n/a	chrV 752,054	C. elegans STR-262 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
25	F32D8.4	F32D8.4	n/a	chrV 10,892,425	F32D8.4 is homologous to Yip1p, an essential Golgi membrane protein in S. cerevisiae that specifically binds the transport GTPases Ypt1p and Ypt31p, as well as Yop1p (the yeast homolog of human ADENOMATOUS POLYPOSIS COLI 1); F32D8.4 is also homologous to the Golgi membrane protein SB140 of H. sapiens, and contains a glutamine/asparagine-rich domain.
26	F57C2.3	F57C2.3	n/a	chrII 14,524,512	contains similarity to Homo sapiens Hypothetical protein; ENSEMBL:ENSP00000265391
27	him-17	T09E8.2	n/a	chrV 13,178,423	him-17 encodes a protein with no obvious non-nematode homologs that localizes to chromatin in germline nuclei, and that is required for double-stranded break (DSB) formation, chiasmata, crossovers, and genetic recombination during meiosis, but is dispensable for homolog pairing and synapsis, spo-11 germline transcription, or the conversion of DSBs into chiasmata; HIM-17 is also required for normal organization of meiotic stages in the germline, and to promote its orderly transistion from (potentially tumorous) mitosis to meiosis; moreover, HIM-17 is required for normal dimethylation of lysine 9 residues on H3 histones in meiotic prophase chromosomes from early pachytene onward, with null him-17(ok424) mutants showing greatly reduced or delayed dimethylation in both hermaphrodite and male germlines; HIM-17 cooperates with GLP-1 to promote meiotic entry, and with EGO-1 to promote germline viability; HIM-17 has six THAP and THAP-like domains, a domain type also found in CDC-14B, CTB-1, GON-14, LIN-15A, LIN-15B, and LIN-36, along with ~100 other proteins such as Drosophila P element transposase and human nuclear proapoptotic factor THAP1; missense or truncating mutations of HIM-17's THAP and THAP-like domains cause partial loss of function, implying that the domains collectively and partially contribute to HIM-17 activity; of the C. elegans genes encoding THAP or THAP-like domains, at least four (lin-15A, lin-15B, lin-36, and him-17) interact genetically with lin-35/Rb.
28	B0507.7	B0507.7	n/a	chrV 8,757,284	contains similarity to Pfam domains PF04960 (Glutaminase) , PF00023 (Ankyrin repeat) (2)contains similarity to Interpro domains IPR015868 (Glutaminase, core), IPR007043 (Glutaminase), IPR012338 (Beta-lactamase-type transpeptidase fold), IPR002110 (Ankyrin)
29	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
30	C15B12.2	C15B12.2	n/a	chrX 6,464,379
31	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
32	srh-68	T21B4.5	n/a	chrII 12,507,810	C. elegans SRH-68 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002379 (ATPase, F0/V0 complex, subunit C)
33	ZK218.1	ZK218.1	n/a	chrV 17,092,954	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
34	ZK673.4	ZK673.4	n/a	chrII 10,453,965	ZK673.4 encodes a protein with a THAP or THAP-like domain; other proteins with such domains include LIN-15A, LIN-15B, LIN-36, and HIM-17 (which all interact with LIN-35/Rb), as well as CDC-14B, CTB-1, GON-14, and ~100 other proteins such as Drosophila P element transposase and human nuclear proapoptotic factor THAP1.
35	tag-68	F37D6.6	n/a	chrI 10,503,512	C. elegans TAG-68 protein; contains similarity to Pfam domains PF03166 (MH2 domain) , PF03165 (MH1 domain) contains similarity to Interpro domains IPR013019 (MAD homology, MH1), IPR008984 (SMAD/FHA domain), IPR001132 (SMAD domain, Dwarfin-type), IPR017855 (SMAD domain-like), IPR013790 (Dwarfin), IPR003619 (MAD homology 1, Dwarfin-type)
36	wht-1	C05D10.3	n/a	chrIII 6,086,042	C05D10.3 encodes an ATP-binding cassette (ABC) transporter; C05D10.3 activity is required for efficient RNA interference (RNAi) of a germline-expressed target, pop-1.
37	tag-256	ZK637.3	n/a	chrIII 8,892,125	C. elegans TAG-256 protein ; contains similarity to Drosophila melanogaster Flybase gene name is CG7739-PA;; FLYBASE:CG7739
38	C05D11.8	C05D11.8	n/a	chrIII 6,424,823	contains similarity to Homo sapiens Isoform 2 of UPF0518 protein C11orf56; ENSEMBL:ENSP00000265978
39	W05B2.4	W05B2.4	n/a	chrIII 10,975,818	contains similarity to Pfam domain PF08393 Dynein heavy chain, N-terminal region 2 contains similarity to Interpro domains IPR011010 (DNA breaking-rejoining enzyme, catalytic core), IPR013602 (Dynein heavy chain, N-terminal region 2)
40	R13H4.6	R13H4.6	n/a	chrV 11,864,309	contains similarity to Archaeoglobus fulgidus Putative protease La homolog type (EC 3.4.21.-).; SW:O29883
41	C06E1.8	C06E1.8	n/a	chrIII 8,596,527	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
42	C07D10.5	C07D10.5	n/a	chrII 7,382,456
43	C16A11.6	C16A11.6	n/a	chrII 4,237,141
44	T09E11.4	T09E11.4	n/a	chrI 12,361,669	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
45	lys-9	C54C8.6	n/a	chrI 12,455,280	C. elegans LYS-9 protein; contains similarity to Interpro domain IPR017853 (Glycoside hydrolase, catalytic core)
46	F08F1.3	F08F1.3	n/a	chrX 8,430,035
47	nhr-55	T01G6.7	n/a	chrV 479,428	nhr-55 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain.
48	clec-38	T25E12.10	n/a	chrV 16,734,718	C. elegans CLEC-38 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
49	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
50	srx-102	F40H7.5	n/a	chrII 3,694,076	C. elegans SRX-102 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)