UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZK218.8	ZK218.8	7e-108	chrV 17,116,486	contains similarity to Pfam domain PF02171 Piwi domain contains similarity to Interpro domains IPR003165 (Stem cell self-renewal protein Piwi), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
2	coh-1	K08A8.3	n/a	chrX 7,470,222	coh-1 encodes a RAD21 homolog that affects embryonic viability and is believed to affect cohesion of sister chromatids in somatic cells; expressed in the distal tip cells of the gonad, embryonic, and somatic cells
3	F21H7.3	F21H7.3	n/a	chrV 16,232,966	contains similarity to Rickettsia conorii Hypothetical protein RC0540.; TR:Q92I80
4	F28B3.4	F28B3.4	n/a	chrI 4,937,314	contains similarity to Pfam domain PF06464 DMAP1-binding Domain contains similarity to Interpro domains IPR010506 (DMAP1-binding), IPR005398 (Tubby, N-terminal)
5	srx-47	E02C12.3	n/a	chrV 9,350,632	C. elegans SRX-47 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
6	F59B2.9	F59B2.9	n/a	chrIII 9,011,467	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
7	C43H6.3	C43H6.3	n/a	chrX 2,408,512	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
8	C40A11.4	C40A11.4	n/a	chrII 2,138,139	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
9	skr-19	R12H7.3	n/a	chrX 13,224,084	The skr-19 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-19(RNAi) animals are at least superficially normal.
10	R03A10.1	R03A10.1	n/a	chrX 15,430,484	contains similarity to Saccharomyces cerevisiae Protein involved in transcription-coupled repair nucleotide exicision repair of UV-induced DNA lesions; homolog of human CSB protein; SGD:YJR035W
11	clec-22	F49A5.3	n/a	chrV 16,859,205	C. elegans CLEC-22 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
12	ndx-6	EEED8.8	n/a	chrII 5,389,360	The ndx-6 gene encodes a NUDIX hydrolase.
13	C38C5.1	C38C5.1	n/a	chrX 5,560,137
14	nhr-172	C54F6.9	n/a	chrV 7,509,779	C. elegans NHR-172 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR015880 (Zinc finger, C2H2-like), IPR001781 (Zinc finger, LIM-type), IPR007087 (Zinc finger, C2H2-type)
15	srz-61	K03D3.4	n/a	chrIV 16,322,140	C. elegans SRZ-61 protein ;
16	lim-7	C04F1.3	n/a	chrI 5,721,019	lim-7 encodes a LIM homeodomain protein; a lim-7 mutation can result in lethality or sterility; lim-7 reporter fusion are specifically expressed in the somatic gonadal sheath cells during the L4 larval stage and continuing through adulthood.
17	air-2	B0207.4	n/a	chrI 5,938,181	air-2 encodes an aurora/Ipl1-related serine/threonine protein kinase that affects embryonic viability and chromosome segregation during meiosis and mitosis and is required for cytokinesis; AIR-2 has two functions during mitosis, one in chromosome segregation, and a second, independent function in cytokinesis through ZEN-4; AIR-2 and ZEN-4 may act in parallel to a second pathway that includes CYK-1; AIR-2 phosphorylates two adjacent, evolutionarily conserved C-terminal serines of the inner centromere protein ICP-1; AIR-2 forms a robust complex with CSC-1, BIR-1, and ICP-1; air-2 is expressed highly in embryos, in the mature oocytes, spermatocytes, and extruded polar bodies.
18	F20D1.8	F20D1.8	n/a	chrX 14,996,828	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
19	col-9	F54B11.1	n/a	chrX 13,590,542	col-9 encodes a collagen protein.
20	str-196	T01G6.3	n/a	chrV 492,687	C. elegans STR-196 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002229 (Blood group Rhesus C/E and D polypeptide)
21	Y56A3A.5	Y56A3A.5	n/a	chrIII 11,889,625	contains similarity to Pfam domain PF01425 Amidase contains similarity to Interpro domains IPR000120 (Amidase signature enzyme), IPR000504 (RNA recognition motif, RNP-1)
22	mls-2	C39E6.4	n/a	chrX 4,760,178	mls-2 encodes a homeodomain protein of the HMX family; during postembryonic development, MLS-2 is required for cell proliferation, cleavage orientation, and fate specification in the mesodermal M lineage; in regulating M lineage proliferation and fate specification, MLS-2 appears to act upstream of CYE-1/cyclin E and HLH-1/CeMyoD, respectively, the latter of which is not expressed in the M lineage in mls-2 mutant animals; MLS-2 is expressed in the nuclei of early proliferating undifferentiated M lineage cells (up to the 8-M stage), in a subset of head neurons, and in cells near the vulva during the L2 and L3 larval stages.
23	fbxb-60	F55C9.7	n/a	chrV 19,298,249	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
24	F35E2.2	F35E2.2	n/a	chrI 11,737,158	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
25	nhr-127	T13F3.3	n/a	chrV 16,263,066	nhr-127 encodes a member of the nuclear hormone receptor family; expressed in hypodermal seam cells from the embryonic 1.5-fold stage until the L1 larval stage.
26	C15H9.4	C15H9.4	n/a	chrX 6,103,253	contains similarity to Danio rerio Novel protein similar to human cerebral protein 11 (HUCEP11).; TR:Q1MTK0
27	sdz-19	F45E6.6	n/a	chrX 12,502,884	C. elegans SDZ-19 protein ;
28	srw-47	K10G4.2	n/a	chrV 17,261,345	C. elegans SRW-47 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300), IPR000276 (GPCR, rhodopsin-like)
29	srx-98	F19B10.8	n/a	chrII 3,670,182	C. elegans SRX-98 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
30	grl-1	C24G6.7	n/a	chrV 5,532,342	grl-1 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich region, and a C-terminal Ground-like (Grl) domain; GRL-1 is expressed in intestine, neurons, and larval arcade cells; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
31	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
32	lon-2	C39E6.1	n/a	chrX 4,743,993	lon-2 encodes a member of the glypican family of heparan sulfate proteoglycans; during development, lon-2 activity is required in the hypodermis for negative regulation of the DBL-1/BMP signaling pathway that regulates body length; genetic analyses indicate that lon-2 functions upstream of dbl-1, and in vitro studies show that LON-2 can bind mammalian BMP2, suggesting that LON-2 may directly interact with DBL-1 to negatively regulate DBL-1/BMP signaling; in addition to expression in hypodermis, LON-2 is expressed strongly in the intestine, particularly the anterior and posterior cells; LON-2 localizes to the cell surface.
33	Y75B8A.8	Y75B8A.8	n/a	chrIII 12,165,797	contains similarity to Plasmodium yoelii yoelii Drosophila melanogaster CG8797 gene product-related (Fragment).; TR:Q7REV3
34	Y116A8B.1	Y116A8B.1	n/a	chrIV 17,216,790	contains similarity to Oryza sativa P0660F12.13 protein (P0614D08.10 protein).; TR:Q94CR6
35	C10A4.3	C10A4.3	n/a	chrX 7,408,027
36	fut-6	T05A7.5	n/a	chrII 4,654,556	C. elegans FUT-6 protein; contains similarity to Pfam domain PF00852 Glycosyltransferase family 10 (fucosyltransferase) contains similarity to Interpro domain IPR001503 (Glycosyl transferase, family 10)
37	lgc-1	T05B4.1	n/a	chrV 4,136,911	C. elegans LGC-1 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR002394 (Nicotinic acetylcholine receptor, N-terminal), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
38	F55C9.3	F55C9.3	n/a	chrV 19,287,274	contains similarity to Pfam domain PF02170 PAZ domain contains similarity to Interpro domain IPR003100 (Argonaute and Dicer protein, PAZ)
39	srt-4	C29G2.4	n/a	chrV 2,578,859	C. elegans SRT-4 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
40	fbxa-137	T27B7.7	n/a	chrV 2,280,414	C. elegans FBXA-137 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
41	fbxb-19	F58E1.9	n/a	chrII 1,688,706	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
42	F55F8.3	F55F8.3	n/a	chrI 5,651,700	contains similarity to Pfam domains PF04047 (Periodic tryptophan protein 2 WD repeat associated presumed domain) , PF00400 (WD domain, G-beta repeat) (5)contains similarity to Interpro domains IPR000009 (Protein phosphatase 2A, regulatory subunit PR55), IPR017441 (Protein kinase ATP binding, conserved site), IPR011046 (WD40 repeat-like), IPR007190 (Periodic tryptophan protein-associated region), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
43	F08B4.4	F08B4.4	n/a	chrIV 8,679,036
44	cki-1	T05A6.1	n/a	chrII 7,811,601	cki-1 encodes a homolog of the mammalian cyclin-dependent kinase inhibitor p27/KIP1 that is required for the arrest of cell division in larval blast lineages, dauer larvae and starved L1 larvae; excess CKI-1 expression prematurely stops cell division while cki-1(RNAi) induces extra cell divisions, indicating that CKI-1 quantitatively regulates the amount of mitosis in postembryonic worms.
45	srv-4	F15E6.7	n/a	chrIV 4,286,920	C. elegans SRV-4 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
46	H25K10.4	H25K10.4	n/a	chrIV 16,226,802	contains similarity to Pseudomonas putida Hypothetical protein.; TR:Q8VMP3
47	F46C8.3	F46C8.3	n/a	chrX 7,526,360
48	T20D4.19	T20D4.19	n/a	chrV 3,431,055	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domain IPR002542 (Protein of unknown function DUF19)
49	K02E7.11	K02E7.11	n/a	chrII 1,075,134
50	flnb-1	C23F12.2	n/a	chrX 9,402,619	C. elegans FLNB-1 protein; contains similarity to Pfam domains PF00630 (Filamin/ABP280 repeat) (2), PF00307 (Calponin homology (CH) domain) (3)contains similarity to Interpro domains IPR001298 (Filamin/ABP280 repeat), IPR014756 (Immunoglobulin E-set), IPR013783 (Immunoglobulin-like fold), IPR000694 (Proline-rich region), IPR016146 (Calponin-homology), IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site), IPR001715 (Calponin-like actin-binding)