UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	nhr-248	ZK218.6	0	chrV 17,103,987	C. elegans NHR-248 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	nhr-79	T26H2.9	0.000002	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
4	F22E12.1	F22E12.1	n/a	chrV 10,455,572	contains similarity to Pfam domain PF00014 Kunitz/Bovine pancreatic trypsin inhibitor domain contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR000694 (Proline-rich region)
5	R13A5.10	R13A5.10	n/a	chrIII 7,582,468	contains similarity to Pfam domain PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region contains similarity to Interpro domains IPR002125 (CMP/dCMP deaminase, zinc-binding), IPR016193 (Cytidine deaminase-like)
6	lin-52	ZK632.13	n/a	chrIII 9,824,348	lin-52 encodes a novel protein that is most closely related to the Drosophila melanogaster CG15929 protein and the human protein XP_040376; lin-52 is a class B synthetic multivulva (synMuv) gene that appears to function with lin-35/Rb to negatively regulate vulval development; in addition, lin-52 is also required for germline and larval development.
7	F37H8.5	F37H8.5	n/a	chrII 11,188,743	contains similarity to Pfam domain PF03227 Gamma interferon inducible lysosomal thiol reductase (GILT) contains similarity to Interpro domain IPR004911 (Gamma interferon inducible lysosomal thiol reductase GILT)
8	ari-1	C27A12.8	n/a	chrI 6,059,904	C. elegans ARI-1 protein; contains similarity to Pfam domain PF01485 IBR domain contains similarity to Interpro domains IPR009060 (UBA-like), IPR002867 (Zinc finger, C6HC-type)
9	ceh-31	C33D12.1	n/a	chrX 3,069,626	ceh-31 encodes a protein containing a homeobox domain.
10	nhr-253	ZK6.4	0.00002	chrV 397,792	C. elegans NHR-253 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000679 (Zinc finger, GATA-type), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
11	T23F1.3	T23F1.3	n/a	chrV 15,456,730	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
12	ZK177.2	ZK177.2	n/a	chrII 5,519,681	contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
13	F54E2.5	F54E2.5	n/a	chrV 2,814,230	contains similarity to Pfam domain PF04789 Protein of unknown function (DUF621) contains similarity to Interpro domains IPR006874 (Protein of unknown function DUF621), IPR003091 (Voltage-dependent potassium channel)
14	F25F6.1	F25F6.1	n/a	chrX 4,445,262
15	F29B9.10	F29B9.10	n/a	chrIV 4,659,258	contains similarity to Interpro domain IPR001911 (Ribosomal protein S21)
16	DH11.4	DH11.4	n/a	chrII 7,993,221	contains similarity to Pfam domain PF00168 C2 domain contains similarity to Interpro domains IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
17	str-30	T27C4.3	n/a	chrV 3,725,910	C. elegans STR-30 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
18	ubq-2	ZK1010.1	n/a	chrIII 12,978,145	ubq-2 encodes a bifunctional protein that contains two domains; an N-terminal ubiquitin peptide, and a C-terminal large ribosomal subunit protein L40 peptide.
19	ctl-1	Y54G11A.6	n/a	chrII 14,304,828	ctl-1 encodes one of three C. elegans catalases; CTL-1 exhibits catalase activity in vitro, and thus likely functions in vivo as an antioxidant enzyme that protects cells from reactive oxygen species; ctl-1 activity contributes to the extended lifespan seen in daf-2 mutant animals; in addition, ctl-1 expression is negatively regulated by DAF-2-mediated insulin signaling; as CTL-1 does not possess a C-terminal peroxisomal targeting signal (PTS), it is predicted to be a cytosolic catalase.
20	H16D19.4	H16D19.4	n/a	chrI 12,642,571	contains similarity to Dictyostelium discoideum Rep protein.; TR:O15924
21	lam-2	C54D1.5	n/a	chrX 7,147,481	lam-2 encodes a laminin gamma subunit; lam-2 activity is required for embryonic development and for regulation of muscle arm extension; loss of lam-2 function via large-scale RNAi screens results in embryonic, larval, and adult lethality, sterility, body morphology defects, and abnormal locomotion.
22	F58H7.2	F58H7.2	n/a	chrIV 942,839	contains similarity to Pfam domain PF01425 Amidase contains similarity to Interpro domains IPR000120 (Amidase signature enzyme), IPR015830 (Amidase, fungi type)
23	T22D1.12	T22D1.12	n/a	chrIV 6,930,087	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
24	T19C3.5	T19C3.5	n/a	chrIII 626,220	contains similarity to Pfam domains PF02886 (LBP / BPI / CETP family, C-terminal domain) , PF01273 (LBP / BPI / CETP family, N-terminal domain) contains similarity to Interpro domain IPR001124 (Lipid-binding serum glycoprotein)
25	M02F4.3	M02F4.3	n/a	chrX 3,038,574	M02F4.3 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C01H6.6, C33D12.2, C52D10.12, R04E5.2, and R13G10.4; by orthology with MAM3, M02F4.3 may participate in metal homoeostasis; M02F4.3, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; M02F4.3 has no obvious function in RNAi assays.
26	T28C12.2	T28C12.2	n/a	chrV 6,330,074	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
27	ZK1320.5	ZK1320.5	n/a	chrII 9,664,562	contains similarity to Interpro domain IPR008107 (Mycoplasma P48 major surface lipoprotein)
28	gst-6	F11G11.3	n/a	chrII 4,880,483	gst-6 encodes a predicted glutathione S-transferase.
29	C49G7.7	C49G7.7	n/a	chrV 4,036,291
30	AC8.3	AC8.3	n/a	chrX 228,920
31	sre-27	Y57A10C.3	n/a	chrII 12,416,469	C. elegans SRE-27 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
32	abcx-1	C56E6.1	n/a	chrII 6,536,117	C. elegans ABCX-1 protein; contains similarity to Pfam domain PF07539 Down-regulated in metastasis contains similarity to Interpro domains IPR011430 (Down-regulated in metastasis), IPR016024 (Armadillo-type fold)
33	C06C3.8	C06C3.8	n/a	chrII 9,388,665	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domains IPR005020 (Protein of unknown function DUF278), IPR001984 (Peptidase S16, Lon protease), IPR006578 (MADF)
34	C28H8.7	C28H8.7	n/a	chrIII 5,886,352	contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
35	slt-1	F40E10.4	n/a	chrX 14,678,771	slt-1 encodes the sole C. elegans homolog of Drosophila Split, a secreted extracellular protein containing leucine-rich and EGF-like repeats that functions as a ligand for the Robo receptor; during C. elegans larval development, slt-1 acts via the SAX-3/Robo receptor, and in parallel with UNC-6/Netrin, to direct ventral axon guidance and guidance at the midline; during embryonic development, slt-1 also functions to regulate anterior-posterior migrations of the CAN neurons; slt-1::gfp reporters are initially expressed at high levels in the anterior part of the embryo, with more moderate levels seen in dorsal tail muscles and lower levels seen in cells in the center of the body; in L1 larvae, slt-1::gfp is expressed in both dorsal and ventral muscles, with higher levels seen in dorsal muscle cells; slt-1::gfp is also expressed in a number of additional cells including some neurons, pharyngeal cells, and the anal sphincter muscle.
36	ckb-2	B0285.9	n/a	chrIII 4,368,967	ckb-2 encodes an isoform of choline kinase whose activity has been verified in vitro; CKB-1 through CKB-4 comprise a related group ('B') of choline kinases; purified CKB-2 has a strong preference for choline over ethanolamine, a specific activity of 2.4 micromol/min/mg protein and a pH optimum near 10.
37	cdd-1	C47D2.2	n/a	chrX 8,209,904	cdd-1 encodes a cytidine deaminase that contains a zinc-binding region; expressed in the intestine.
38	F31B12.2	F31B12.2	n/a	chrX 10,822,704	contains similarity to Mus musculus Splicing factor, arginine/serine-rich 12 (Serine-arginine-richssplicing regulatory protein 86) (SRrp86).; SW:SFRC_MOUSE
39	T21D12.12	T21D12.12	n/a	chrIV 267,384	contains similarity to Pfam domain PF00014 Kunitz/Bovine pancreatic trypsin inhibitor domain contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR006150 (Cysteine-rich repeat)
40	F09G2.3	F09G2.3	n/a	chrV 7,186,673	contains similarity to Pfam domain PF01384 Phosphate transporter family contains similarity to Interpro domain IPR001204 (Phosphate transporter)
41	kin-3	B0205.7	n/a	chrI 10,735,304	kin-3 encodes an ortholog of the catalytic subunit of casein kinase II alpha, which in Drosophila and mammals is required for normal circadian rhythms, and which directly phosphorylates the Drosophila PERIOD protein (which itself regulates circadian rhythms); by analogy, KIN-3 might be expected to help regulate heterochronic functions dependent on such proteins as LIN-42.
42	ugt-38	F10D2.7	n/a	chrV 7,146,544	C. elegans UGT-38 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR003567 (Cytochrome c-type biogenesis protein), IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
43	C31A11.5	C31A11.5	n/a	chrV 16,304,427	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
44	lips-10	F14E5.5	n/a	chrII 8,440,581	C. elegans LIPS-10 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
45	F55H12.2	F55H12.2	n/a	chrI 8,868,112	contains similarity to Interpro domain IPR000242 (Tyrosine specific protein phosphatase)
46	C01H6.2	C01H6.2	n/a	chrI 7,206,143	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
47	W08F4.7	W08F4.7	n/a	chrII 576,333
48	Y54G11A.4	Y54G11A.4	n/a	chrII 14,294,300	contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site), IPR000023 (Phosphofructokinase)
49	F44D12.2	F44D12.2	n/a	chrIV 10,015,214	contains similarity to Pfam domain PF01064 Activin types I and II receptor domain contains similarity to Interpro domain IPR000472 (TGF-beta receptor/activin receptor, type I/II)
50	Y6B3B.9	Y6B3B.9	n/a	chrI 13,743,033	contains similarity to Pfam domain PF04031 Las1-like contains similarity to Interpro domain IPR007174 (Las1-like)