UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZK218.3	ZK218.3	4e-152	chrV 17,098,315	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	F08F8.2	F08F8.2	n/a	chrIII 7,360,724	contains similarity to Pfam domain PF00368 Hydroxymethylglutaryl-coenzyme A reductase contains similarity to Interpro domains IPR004554 (Hydroxymethylglutaryl-CoA reductase, class I, catalytic), IPR009029 (Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding), IPR002202 (Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)
4	F31D5.4	F31D5.4	n/a	chrII 4,179,466	contains similarity to Pfam domain PF01825 Latrophilin/CL-1-like GPS domain contains similarity to Interpro domain IPR000203 (GPS)
5	sra-21	F28C12.5	n/a	chrI 12,700,219	C. elegans SRA-21 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
6	cyp-33C3	F41B5.4	n/a	chrV 2,243,821	C. elegans CYP-33C3 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
7	F18A12.2	F18A12.2	n/a	chrII 3,415,610
8	ZC581.3	ZC581.3	n/a	chrI 6,653,325	contains similarity to Interpro domain IPR011046 (WD40 repeat-like)
9	sra-2	AH6.6	n/a	chrII 9,529,242	C. elegans SRA-2 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
10	scrm-2	ZK1053.5	n/a	chrI 13,235,906	scrm-2 encodes a putative phospholipid scramblase homologous to human PLSCR1-5, and paralogous to other C. elegans SCRMs (e.g., SCRM-1); in apoptotic germline cells, SCRM-2 is fully dispensable for normally rapid engulfment and largely dispensable for phosphatidylserine exposure; SCRM-2 does not bind WAH-1 in vitro, and scrm-2(tm650) mutants have no obvious phenotype.
11	T20D4.6	T20D4.6	n/a	chrV 3,411,676	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
12	T06C12.11	T06C12.11	n/a	chrV 15,893,552	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
13	W05F2.7	W05F2.7	n/a	chrI 3,357,913	contains similarity to Interpro domain IPR000694 (Proline-rich region)
14	F10E7.6	F10E7.6	n/a	chrII 7,113,277
15	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
16	B0511.12	B0511.12	n/a	chrI 10,657,939	B0511.12 encodes an ortholog of Drosophila PECANEX, and thus may participate in GLP-1/LIN-12 signalling.
17	T27A3.7	T27A3.7	n/a	chrI 6,108,746	contains similarity to Pfam domain PF00130 Phorbol esters/diacylglycerol binding domain (C1 domain) contains similarity to Interpro domains IPR001965 (Zinc finger, PHD-type), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding), IPR001781 (Zinc finger, LIM-type)
18	B0496.6	B0496.6	n/a	chrIV 7,419,545	contains similarity to Pfam domain PF03134 TB2/DP1, HVA22 family contains similarity to Interpro domain IPR004345 (TB2/DP1 and HVA22 related protein)
19	Y51B9A.4	Y51B9A.4	n/a	chrII 9,408,334	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
20	dnj-9	F11G11.7	n/a	chrII 4,854,916	This gene encodes a protein containing a DnaJ ('J') domain.
21	F52F12.7	F52F12.7	n/a	chrI 9,929,922	F52F12.7 is orthologous to the human gene STEROIDOGENIC ACUTE REGULATORY PROTEIN (STAR; OMIM:600617), which when mutated leads to disease.
22	F14F9.2	F14F9.2	n/a	chrV 5,145,296	contains similarity to Homo sapiens Acidic repeat-containing protein; ENSEMBL:ENSP00000362799
23	T11F8.4	T11F8.4	n/a	chrIV 5,475,352	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
24	C06B3.2	C06B3.2	n/a	chrV 13,901,062	contains similarity to Pfam domain PF00350 Dynamin family contains similarity to Interpro domain IPR001401 (Dynamin, GTPase region)
25	T20D4.9	T20D4.9	n/a	chrV 3,404,051	T20D4.9 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; T20D4.9 has no clear orthologs in other organisms.
26	rsp-2	W02B12.2	n/a	chrII 11,452,115	C. elegans RSP-2 protein; contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
27	str-56	T06C12.3	n/a	chrV 15,873,145	C. elegans STR-56 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR003569 (Cytochrome c-type biogenesis protein CcbS)
28	K02B2.6	K02B2.6	n/a	chrIV 5,961,963
29	F12F6.7	F12F6.7	n/a	chrIV 11,560,335	contains similarity to Pfam domain PF04042 DNA polymerase alpha/epsilon subunit B contains similarity to Interpro domain IPR007185 (DNA polymerase alpha/epsilon, subunit B)
30	nsh-1	F20H11.2	n/a	chrIII 6,595,590	C. elegans NSH-1 protein; contains similarity to Pfam domain PF00271 Helicase conserved C-terminal domain contains similarity to Interpro domains IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
31	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
32	nhr-89	E03H4.13	n/a	chrI 12,440,583	C. elegans NHR-89 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
33	F26E4.2	F26E4.2	n/a	chrI 9,759,327	contains similarity to Pasteurella haemolytica HSDR.; TR:P95512
34	Y57A10C.10	Y57A10C.10	n/a	chrII 12,440,350	contains similarity to Pfam domain PF01838 (Domain of unknown function DUF40)
35	F39B2.7	F39B2.7	n/a	chrI 14,772,840	contains similarity to Pfam domain PF01926 GTPase of unknown function contains similarity to Interpro domains IPR005289 (GTP-binding), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR002917 (GTP-binding protein, HSR1-related), IPR003593 (AAA+ ATPase, core), IPR006073 (GTP1/OBG), IPR004520 (tRNA modification GTPase TrmE)
36	Y75B12B.8	Y75B12B.8	n/a	chrV 15,201,905	contains similarity to Homo sapiens Xylosyltransferase I; ENSEMBL:ENSP00000261381
37	sec-5	T23G7.4	n/a	chrII 9,175,083	The sec-5 gene encodes an ortholog of SEC5 in S. cerevisiae, a component of the exocyst complex required genetically for endocytosis and for normal cellular morphology in the intestine.
38	B0491.1	B0491.1	n/a	chrII 11,349,105	contains similarity to Pfam domain PF05007 Mannosyltransferase (PIG-M) contains similarity to Interpro domain IPR007704 (Mannosyltransferase, DXD)
39	tag-89	H02I12.3	n/a	chrIV 11,395,562	C. elegans TAG-89 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
40	twk-4	ZK1067.5	n/a	chrII 9,192,128	C. elegans TWK-4 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR003938 (Potassium channel, voltage-dependent, EAG/ELK/ERG), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
41	srx-42	C06B3.11	n/a	chrV 13,921,696	C. elegans SRX-42 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
42	fbxa-144	F44G3.8	n/a	chrV 16,132,206	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
43	fbxa-103	F09C3.4	n/a	chrI 14,288,863	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
44	T24H10.5	T24H10.5	n/a	chrII 9,103,999	contains similarity to Arthrobacter sp C2-2 Putative histidine kinase.; TR:Q8KRF2
45	srh-293	K08G2.8	n/a	chrV 15,866,710	C. elegans SRH-293 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
46	C04B4.4	C04B4.4	n/a	chrX 12,291,546	contains similarity to Saccharomyces cerevisiae Nucleolar protein involved in exit from mitosis; SGD:YJL076W
47	T22C8.2	T22C8.2	n/a	chrII 8,616,005	contains similarity to Pfam domain PF01630 Hyaluronidase contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001968 (Glycoside hydrolase, family 56), IPR000742 (EGF-like, type 3), IPR017853 (Glycoside hydrolase, catalytic core), IPR013032 (EGF-like region, conserved site), IPR017430 (Glycoside hydrolase,family 56,Hyaluronidase), IPR001329 (Glycoside hydrolase, family 56, allergen Api/Dol m 2)
48	ZC487.3	ZC487.3	n/a	chrV 6,723,598
49	T10F2.2	T10F2.2	n/a	chrIII 5,164,574	T10F2.2 is orthologous to the human gene SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER; ORNITHINE TRANSPORTER) MEMBER 15 (SLC25A15; OMIM:603861), which when mutated leads to disease.
50	pdr-1	K08E3.7	n/a	chrIII 13,772,270	pdr-1 encodes an ortholog of human parkin (PARK2; OMIM:602544), which when mutated leads to the juvenile 2 form of Parkinson disease (OMIM:600116).