UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	his-14	ZK131.8	1e-41	chrII 13,819,690	his-14 encodes an H4 histone.
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	his-26	ZK131.1	1e-41	chrII 13,825,596	his-26 encodes an H4 histone.
4	T28C6.8	T28C6.8	n/a	chrIV 8,830,136	contains similarity to Interpro domain IPR006629 (LPS-induced tumor necrosis factor alpha factor)
5	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
6	C35E7.8	C35E7.8	n/a	chrI 10,809,484
7	C10G8.3	C10G8.3	n/a	chrV 5,313,573	contains similarity to Pfam domain PF00014 Kunitz/Bovine pancreatic trypsin inhibitor domain contains similarity to Interpro domain IPR002223 (Proteinase inhibitor I2, Kunitz metazoa)
8	ugt-24	C49A9.8	n/a	chrIV 6,208,144	C. elegans UGT-24 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
9	lin-11	ZC247.3	n/a	chrI 10,251,797	lin-11 encodes a predicted LIM homeodomain transcription factor that affects vulval development, neuronal development and fate specification, utse cell differentiation, and fertility; it is expressed in some neurons, the vulva, pi cells and their progeny, and the spermatheca.
10	his-15	ZK131.9	n/a	chrII 13,818,464	his-15 encodes an H2B histone.
11	F48E8.3	F48E8.3	n/a	chrIII 5,462,687	contains similarity to Pfam domains PF00890 (FAD binding domain) , PF01266 (FAD dependent oxidoreductase) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR010960 (Flavocytochrome c), IPR006076 (FAD dependent oxidoreductase), IPR003953 (Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal), IPR016040 (NAD(P)-binding)
12	cyp-37B1	F28G4.1	n/a	chrV 16,279,374	C. elegans CYP-37B1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
13	his-1	T10C6.14	1e-41	chrV 16,042,648	his-1 encodes an H4 histone; his-1 is contained within the histone gene cluster HIS1; transcript analysis suggests that it encodes the major class of H4 transcripts.
14	F35F10.10	F35F10.10	n/a	chrV 3,304,887	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
15	his-11	ZK131.5	n/a	chrII 13,821,955	his-11 encodes an H2B histone; by homology, HIS-11 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-11 is a replication-dependent histone locus that resides in the HIS3 cluster on chromosome II.
16	Y106G6A.1	Y106G6A.1	n/a	chrI 9,937,203	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
17	htp-3	F57C9.5	n/a	chrI 4,828,421	C. elegans HTP-3 protein; contains similarity to Pfam domain PF02301 HORMA domain contains similarity to Interpro domain IPR003511 (DNA-binding HORMA)
18	W09H1.5	W09H1.5	n/a	chrII 13,186,582	contains similarity to Pfam domains PF00107 (Zinc-binding dehydrogenase) , PF08240 (Alcohol dehydrogenase GroES-like domain) contains similarity to Interpro domains IPR013149 (Alcohol dehydrogenase, zinc-binding), IPR011032 (GroES-like), IPR013154 (Alcohol dehydrogenase GroES-like), IPR002085 (Alcohol dehydrogenase superfamily, zinc-containing), IPR016040 (NAD(P)-binding)
19	F26F2.7	F26F2.7	n/a	chrV 20,581,046	contains similarity to Pfam domain PF05346 Eukaryotic membrane protein family contains similarity to Interpro domain IPR008010 (Protein of unknown function DUF747, CMV receptor)
20	K09H9.7	K09H9.7	n/a	chrI 3,151,195	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
21	K05F6.8	K05F6.8	n/a	chrII 1,567,541	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
22	skr-6	Y37H2C.2	n/a	chrV 18,269,765	The skr-6 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-6(RNAi) animals are at least superficially normal.
23	his-10	ZK131.4	1e-41	chrII 13,823,128	his-10 encodes an H4 histone.
24	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
25	nspb-11	F35C5.10	n/a	chrII 12,907,461	C. elegans NSPB-11 protein ;
26	C35D10.5	C35D10.5	n/a	chrIII 4,862,879	contains similarity to Pfam domain PF03981 Ubiquinol-cytochrome C chaperone contains similarity to Interpro domain IPR007129 (Ubiquinol-cytochrome C chaperone)
27	K10H10.5	K10H10.5	n/a	chrII 14,502,114	contains similarity to Interpro domain IPR001030 (Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)
28	K08C7.6	K08C7.6	n/a	chrIV 10,685,135	contains similarity to Arabidopsis thaliana Tetratricoredoxin.; TR:Q8VWG7
29	T25D10.4	T25D10.4	n/a	chrII 6,408,988
30	srxa-4	F18E3.1	n/a	chrV 7,421,068	C. elegans SRXA-4 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
31	srbc-22	C45H4.8	n/a	chrV 2,157,702	C. elegans SRBC-22 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
32	C32B5.14	C32B5.14	n/a	chrII 966,320
33	T27F6.7	T27F6.7	n/a	chrI 12,496,077	contains similarity to Timmia bavarica NADH dehydrogenase subunit 4 (Fragment).; TR:Q94YV9
34	K09C4.2	K09C4.2	n/a	chrX 3,297,833
35	sago-1	K12B6.1	n/a	chrV 6,306,024	sago-1 encodes an Argonaute homolog that is partially required for the amplification phase of RNAi responses; a multiply mutant strain (MAGO), consisting of ppw-1(tm914), sago-1(tm1195), sago-2(tm894), F58G1.1(tm1019), C06A1.4(tm887), and M03D4.6(tm1144) alleles, is completely resistant to both germline and somatic RNAi; sago-1 is genetically redundant with ppw-1 and sago-2, with any one of these genes being able to transgenically partially restore the deficiency of MAGO worms; GFP-tagged SAGO-1 binds small secondary siRNAs produced by RNAi against GFP; MAGO is not transgenically rescued by rde-1; strains overexpressing GFP::SAGO-1 exhibited an enhanced level of RNAi overall, suggesting that SAGO-1 and its congeners are rate-limiting in vivo for RNAi.
36	stdh-4	F25G6.5	n/a	chrV 8,550,589	stdh-4 encodes a putative steroid dehydrogenase expressed in larval and adult pharynx; STDH-4 is orthologous to human HSD17B3 (OMIM:605573, mutated in pseudohermaphroditism), HSD17B12 (OMIM:609574), and HSDL1, and paralogous to LET-767 and STDH-1/-3; STDH-4 has no obvious function in mass RNAi assays.
37	F25E2.2	F25E2.2	n/a	chrX 808,888	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
38	uev-3	F26H9.7	n/a	chrI 9,311,457	uev-3 encodes a ubiquitin-conjugating enzyme (UBC or E2) variant that contains the UBC motif, but lacks the critical active-site cysteine residue necessary for catalytic activity; as loss of UEV-3 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UEV-3 in C. elegans development and/or behavior is not yet known; based on similarity to Saccharomyces cerevisiae and human proteins, however, UEV-3 may play a role in cell cycle control or response to stress or DNA damage.
39	K12B6.8	K12B6.8	n/a	chrV 6,310,389	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding)
40	ocam-1	T02B5.2	n/a	chrV 14,167,452	T02B5.2 encodes a protein with an OCAM domain, a nematode-specific motif conserved between T02B5.2 and two other nematode ONECUT homeobox proteins (CEH-21 and CEH-41); this gene is probably derived from a ONECUT gene that lost both tit cut domain and its homeodomain; T02B5.2 has no obvious function in mass RNAi assays.
41	str-136	F21F8.9	n/a	chrV 8,278,202	C. elegans STR-136 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003002 (7TM chemoreceptor, subfamily 1)
42	ZK1307.2	ZK1307.2	n/a	chrII 9,653,433	contains similarity to Dictyostelium discoideum Hypothetical protein.; TR:Q8T1G2
43	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
44	mab-7	ZC13.4	n/a	chrX 895,155	mab-7 encodes a protein with a hydrophobic type II transmembrane region at the N-terminus, an EGF-like motif, a ShKT motif and a long C-terminus; mab-7 is involved in morphogenesis of the male tail, specifically affecting the structural cells, neuronal processes and the hypodermal sheath of the sensory rays, as such, it affects mating in males; a mab-7 promoter-gfp construct is expressed in hypodermis, body seam, ray structural cells, and several neurons in the head and tail region.
45	F35F10.5	F35F10.5	n/a	chrV 3,285,611
46	C14C11.7	C14C11.7	n/a	chrV 5,665,729
47	C01G5.6	C01G5.6	n/a	chrIV 6,523,650	contains similarity to Interpro domain IPR009007 (Peptidase aspartic, catalytic)
48	C44B12.6	C44B12.6	n/a	chrIV 1,131,250	contains similarity to Interpro domain IPR010345 (Interleukin-17)
49	B0244.7	B0244.7	n/a	chrIII 5,732,127	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
50	Y37D8A.4	Y37D8A.4	n/a	chrIII 12,837,949	contains similarity to Pfam domain PF00017 SH2 domain contains similarity to Interpro domain IPR000980 (SH2 motif)