UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZK1307.9	ZK1307.9	4e-171	chrII 9,650,113	contains similarity to Pfam domain PF04502 Family of unknown function (DUF572) contains similarity to Interpro domain IPR007590 (Protein of unknown function DUF572)
2	str-102	R08H2.13	n/a	chrV 15,385,819	C. elegans STR-102 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
3	T01G6.10	T01G6.10	n/a	chrV 502,683	contains similarity to Pfam domains PF01370 (NAD dependent epimerase/dehydratase family) , PF00106 (short chain dehydrogenase) contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR001509 (NAD-dependent epimerase/dehydratase), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
4	F46F3.3	F46F3.3	n/a	chrV 11,668,418	contains similarity to Dictyostelium discoideum Hypothetical protein.; TR:Q86J27
5	F35E8.9	F35E8.9	n/a	chrV 15,916,920	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
6	F39G3.6	F39G3.6	n/a	chrV 4,712,695	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
7	R10E11.5	R10E11.5	n/a	chrIII 9,787,703	contains similarity to Homo sapiens cDNA FLJ77065, highly similar to Homo sapiens golgi autoantigen, golgin subfamily a, 4 (GOLGA4), mRNA; ENSEMBL:ENSP00000349305
8	ZC190.10	ZC190.10	n/a	chrV 8,696,074
9	K09H9.4	K09H9.4	n/a	chrI 3,134,515	contains similarity to Interpro domains IPR015706 (RNA-directed DNA polymerase (reverse transcriptase), related), IPR003286 (Nematode reverse transcriptase-like)
10	his-45	B0035.10	n/a	chrIV 11,326,794	his-45 encodes an H3 histone.
11	srsx-1	F40D4.5	n/a	chrV 17,177,360	C. elegans SRSX-1 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
12	F59B10.2	F59B10.2	n/a	chrII 10,508,511	contains similarity to Interpro domains IPR003993 (Treacher Collins syndrome, treacle), IPR005819 (Histone H5)
13	pde-5	C32E12.2	n/a	chrI 5,198,010	C. elegans PDE-5 protein; contains similarity to Pfam domains PF01590 (GAF domain) , PF00233 (3'5'-cyclic nucleotide phosphodiesterase) contains similarity to Interpro domains IPR002073 (3'5'-cyclic nucleotide phosphodiesterase), IPR003018 (GAF), IPR003607 (Metal-dependent phosphohydrolase, HD region)
14	R03D7.2	R03D7.2	n/a	chrII 10,933,886	contains similarity to Rhodopirellula baltica DNA-binding protein SMUBP-2.; TR:Q7UWP1
15	srsx-12	C13D9.5	n/a	chrV 4,980,446	C. elegans SRSX-12 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
16	srd-69	H04J21.2	n/a	chrIII 2,364,601	C. elegans SRD-69 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
17	W03G1.4	W03G1.4	n/a	chrIV 509,467	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
18	srg-5	T12A2.11	n/a	chrIII 6,263,078	C. elegans SRG-5 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
19	ubc-21	C06E2.3	n/a	chrX 8,870,667	C. elegans UBC-21 protein; contains similarity to Pfam domain PF00179 Ubiquitin-conjugating enzyme contains similarity to Interpro domains IPR000608 (Ubiquitin-conjugating enzyme, E2), IPR009060 (UBA-like), IPR016135 (Ubiquitin-conjugating enzyme/RWD-like), IPR015940 (Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)
20	B0379.6	B0379.6	n/a	chrI 10,097,535	contains similarity to Saccharomyces cerevisiae Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA; SGD:YOR310C
21	C04E6.3	C04E6.3	n/a	chrV 5,920,241
22	sri-70	Y61B8B.1	n/a	chrV 17,303,714	C. elegans SRI-70 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000883 (Cytochrome c oxidase, subunit I)
23	F21F8.2	F21F8.2	n/a	chrV 8,275,167	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001461 (Peptidase A1)
24	his-5	F45F2.3	n/a	chrV 8,535,370	his-5 encodes an H4 histone.
25	srj-57	T03D3.14	n/a	chrV 2,854,982	C. elegans SRJ-57 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
26	B0238.7	B0238.7	n/a	chrV 5,261,699	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
27	uev-3	F26H9.7	n/a	chrI 9,311,457	uev-3 encodes a ubiquitin-conjugating enzyme (UBC or E2) variant that contains the UBC motif, but lacks the critical active-site cysteine residue necessary for catalytic activity; as loss of UEV-3 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UEV-3 in C. elegans development and/or behavior is not yet known; based on similarity to Saccharomyces cerevisiae and human proteins, however, UEV-3 may play a role in cell cycle control or response to stress or DNA damage.
28	F35F10.10	F35F10.10	n/a	chrV 3,304,887	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
29	C02F12.5	C02F12.5	n/a	chrX 3,671,203	C02F12.5 encodes a putatively secreted protein with a Kunitz/bovine pancreatic trypsin inhibitor domain; C02F12.5 has no obvious function in mass RNAi assays.
30	F13B12.3	F13B12.3	n/a	chrIV 10,441,433	contains similarity to Tetraodon nigroviridis Chromosome 12 SCAF8721, whole genome shotgun sequence. (Fragment).; TR:Q4T6K3
31	fut-2	EGAP9.2	n/a	chrV 6,574,873	fut-2 encodes a unique alpha 1,2-fucosyltransferase specifically expressed in intestinal cells of larval and adult animals; recombinant FUT-2 expressed in human 293T cells exhibits a novel acceptor specificity profile compared with mammalian alpha 1,2-fucosyltransferases and the predicted protein shares very low amino acid identity with human alpha 1,2-fucosyltransferases, but its predicted type 2 topology and domain structure are typical of other glucosyltransferases.
32	C37E2.3	C37E2.3	n/a	chrX 14,180,268	contains similarity to Pfam domain PF04750 FAR-17a/AIG1-like protein contains similarity to Interpro domains IPR006838 (FAR-17a/AIG1-like protein), IPR002208 (SecY protein)
33	K12D9.1	K12D9.1	n/a	chrV 3,015,027	contains similarity to Pfam domains PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) , PF01209 (ubiE/COQ5 methyltransferase family) contains similarity to Interpro domains IPR004033 (UbiE/COQ5 methyltransferase), IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
34	str-183	T13F3.1	n/a	chrV 16,276,778	C. elegans STR-183 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
35	T02B11.6	T02B11.6	n/a	chrV 887,079	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
36	taf-3	C11G6.1	n/a	chrX 16,334,113	taf-3 encodes the C. elegans ortholog of mammalian TAF3(TAFII140), a component of the RNA polymerase II TFIID transcription complex; TAF-3 contains a histone fold-like domain in its N-terminus and by homology, is predicted to function in transcriptional regulation; however, as loss of taf-3 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of taf-3 in C. elegans development and/or behavior is not yet known.
37	F07H5.7	F07H5.7	n/a	chrII 8,793,642
38	lev-8	C35C5.5	n/a	chrX 11,562,231	lev-8 encodes a novel nicotinic acetylcholine receptor (nAChR) alpha subunit that is a member of the ACR-8 group of nAChR subunits; LEV-8 activity is required for normal rates of pharyngeal pumping and for fully wild-type responses (increased egg laying and body wall muscle contraction) to the nAChR agonist and antihelmintic levamisole; expression of a LEV-8::GFP reporter construct begins at the L1 larval stage and is detected in neurons, body wall and uterine muscle cells, and socket cells of the IL and OL mechanosensory neurons; expression in body wall muscles is strongest in the anterior, consistent with increased levamisole resistance of head, or anterior, muscles seen in lev-8 mutant animals.
39	sos-1	T28F12.3	n/a	chrV 4,533,472	The sos-1 gene, also known as let-341, encodes an ortholog of Son of sevenless, a guanine nucleotide exchange factor that affects viability, sex myoblast migration, vulval induction, and oogenesis; it acts genetically downstream of let-23 and upstream of let-60 with respect to vulval development.
40	T27E7.6	T27E7.6	n/a	chrIV 14,541,148	contains similarity to Interpro domains IPR000533 (Tropomyosin), IPR002291 (Phosphorylase kinase, gamma catalytic subunit)
41	B0250.4	B0250.4	n/a	chrV 20,456,958	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
42	C07A9.10	C07A9.10	n/a	chrIII 9,685,849	contains similarity to Pfam domain: PF00442 (Ubiquitin carboxyl-terminal hydrolases family 2), Score=28.0, E-value=1e-05, N=1
43	T27A8.1	T27A8.1	n/a	chrX 16,052,166	T27A8.1 encodes a putative metallocarboxypeptidase orthologous to human AEBP1 (OMIM:602981) and carboxypeptidase D, E, M, N, X2, and Z precursors; T27A8.1 and its human orthologs, along with other proteins, comprise an M14B peptidase subfamily; T27A8.1 has no obvious function in mass RNAi assays.
44	egl-38	C04G2.7	n/a	chrIV 10,108,695	The egl-38 gene encodes a Pax5 homolog.
45	gcy-4	ZK970.5	n/a	chrII 10,306,418	gcy-4 encodes a predicted transmembrane guanylyl cyclase; by homology, GCY-4 may function as a chemosensory receptor; however, as loss of gcy-4 activity via mutation or large-scale RNAi screens results in no obvious abnormalities, the precise role of gcy-4 in C. elegans development and/or behavior is not yet known; the sole gcy-4 ::GFP reporter construct reported to date did not produce any specific GFP signals.
46	Y106G6E.4	Y106G6E.4	n/a	chrI 10,222,213	contains similarity to Pfam domain PF01812 5-formyltetrahydrofolate cyclo-ligase family contains similarity to Interpro domain IPR002698 (5-formyltetrahydrofolate cyclo-ligase)
47	K08F9.1	K08F9.1	n/a	chrV 15,138,399	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
48	Y102A5C.27	Y102A5C.27	n/a	chrV 16,988,446	contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
49	F57B9.1	F57B9.1	n/a	chrIII 6,962,648	contains similarity to Pfam domain PF01243 Pyridoxamine 5'-phosphate oxidase contains similarity to Interpro domains IPR012349 (FMN-binding split barrel), IPR011576 (Pyridoxamine 5'-phosphate oxidase-related, FMN-binding core), IPR009002 (FMN-binding split barrel, related), IPR000659 (Pyridoxamine 5'-phosphate oxidase)
50	let-23	ZK1067.1	n/a	chrII 9,202,659	let-23 encodes an EGF-receptor-family transmembrane tyrosine kinase that affects viability, inductive signaling during development of the vulva, male spicule formation, posterior development of the epidermis, ovulation and behavioral quiescience during lethargus; it is genetically upstream of the let-60/RAS pathway with respect to viability and vulval development, is upstream of phosopholipase C gamma with respect to fertility and quiesence, and is expressed in vulval precursor cells and the ALA neuron.