UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZK1290.5	ZK1290.5	0	chrII 7,530,168	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
2	F25H9.1	F25H9.1	n/a	chrV 13,454,521	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
3	M01B2.8	M01B2.8	n/a	chrV 15,260,488	contains similarity to Pfam domain PF03380 Caenorhabditis protein of unknown function, DUF282 contains similarity to Interpro domain IPR005044 (Protein of unknown function DUF282, Caenorhabditis species)
4	gcy-34	M04G12.3	n/a	chrV 13,384,440	gcy-34 encodes a predicted soluble guanylyl cyclase that is expressed in four candidate sensory neurons connected to the pseudocoelom, URXL, URXR, AQR, and PQR; as loss of gcy-34 activity via RNA-mediated interference does not result in any abnormalities, the precise role of GCY-34 in C. elegans development and/or behavior is not yet known; GCY-34 expression in neurons connected to the pseudocoelom suggests, however, that GCY-34 may play a role in fluid homeostasis.
5	C16B8.2	C16B8.2	n/a	chrX 3,963,843
6	T10B5.2	T10B5.2	n/a	chrV 1,849,449
7	hlh-15	C43H6.8	n/a	chrX 2,413,123	C. elegans HLH-15 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
8	klp-8	C15C7.2	n/a	chrX 3,162,174	klp-8 encodes an atypical kinesin-like motor protein with the motor domain in the N-terminus; the motor domain of KLP-8 exhibits poor homology to the globular motor domain of the kinesin heavy chain.
9	pink-1	EEED8.9	n/a	chrII 5,394,469	pink-1 encodes a predicted serine/threonine protein kinase that is most similar to the Drosophila and human PINK1 (PTEN-induced kinase) protein kinases, the latter of which has been implicated in familial forms of Parkinson's disease; although loss of C. elegans pink-1 activity via large-scale RNAi screens results in no obvious abnormalities, studies in Drosophila indicate that Drosophila PINK1 is a mitochondrial protein that genetically interacts with Drosophila parkin and is essential for maintaining mitochondrial function and integrity in several tissues, including flight muscles and dopaminergic neurons.
10	pqn-29	F10F2.9	n/a	chrIII 4,645,137	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
11	C45G9.7	C45G9.7	n/a	chrIII 5,046,619	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domains IPR017268 (Tax1-binding protein 3), IPR001478 (PDZ/DHR/GLGF)
12	C32B5.13	C32B5.13	n/a	chrII 961,636	contains similarity to Pfam domain PF00112 Papain family cysteine protease contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000668 (Peptidase C1A, papain C-terminal)
13	srg-3	C18F10.6	n/a	chrIII 6,269,673	C. elegans SRG-3 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
14	T05E12.3	T05E12.3	n/a	chrV 17,077,410	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
15	Y18D10A.9	Y18D10A.9	n/a	chrI 12,855,664	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
16	T09E8.3	T09E8.3	n/a	chrV 13,180,913	contains similarity to Pfam domain PF03311 Cornichon protein contains similarity to Interpro domain IPR003377 (Cornichon)
17	pxn-2	K09C8.5	n/a	chrX 10,975,651	C. elegans PXN-2 protein; contains similarity to Pfam domains PF00047 (Immunoglobulin domain) (2), PF00560 (Leucine Rich Repeat) (3), PF01462 (Leucine rich repeat N-terminal domain) , PF07679 (Immunoglobulin I-set domain) (2), PF03098 (Animal haem peroxidase) contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR013098 (Immunoglobulin I-set), IPR010255 (Haem peroxidase), IPR003596 (Immunoglobulin V-set, subgroup), IPR013783 (Immunoglobulin-like fold), IPR003591 (Leucine-rich repeat, typical subtype), IPR007110 (Immunoglobulin-like), IPR002007 (Haem peroxidase, animal), IPR000372 (Leucine-rich repeat, cysteine-rich flanking region, N-terminal), IPR003599 (Immunoglobulin subtype), IPR013151 (Immunoglobulin)
18	wts-1	T20F10.1	n/a	chrI 10,294,898	C. elegans WTS-1 protein; contains similarity to Pfam domains PF00069 (Protein kinase domain) , PF00433 (Protein kinase C terminal domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR000694 (Proline-rich region), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000961 (Protein kinase, C-terminal)
19	H37A05.1	H37A05.1	n/a	chrV 13,652,199	H37A05.1 encodes a putative phosphatidic acid phosphatase orthologous to budding yeast PAH1 and human LPIN1 (OMIM:605518), LPIN2 (OMIM:605519, mutated in Majeed syndrome), and LPIN3 (OMIM:605520); H37A05.1 is expressed in vulval muscle; in mass RNAi assays, H37A05.1 is required for the osmotic integrity of eggs and for normal larval growth, body thickness, locomotion, and fertility; by orthology, H37A05.1 is expected to be dephosphorylated by SCPL-2.
20	bli-5	F45G2.5	n/a	chrIII 13,428,598	bli-5 encodes a protease inhibitor that affects the integrity of the cuticle and the development of the bursa in the adult male.
21	R11G1.1	R11G1.1	n/a	chrX 3,663,173	contains similarity to Pfam domain PF00057 Low-density lipoprotein receptor domain class A contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich)
22	H12D21.10	H12D21.10	n/a	chrV 14,905,809	contains similarity to Pfam domain PF04577 Protein of unknown function (DUF563) contains similarity to Interpro domain IPR007657 (Protein of unknown function DUF563)
23	F28C1.1	F28C1.1	n/a	chrV 12,452,041	contains similarity to Drosophila melanogaster Flybase gene name is CG6695-PA;; FLYBASE:CG6695
24	alh-10	C54D1.4	n/a	chrX 7,142,025	C. elegans ALH-10 protein; contains similarity to Pfam domain PF00171 Aldehyde dehydrogenase family contains similarity to Interpro domains IPR016163 (Aldehyde dehydrogenase, C-terminal), IPR016162 (Aldehyde dehydrogenase, N-terminal), IPR016161 (Aldehyde/histidinol dehydrogenase), IPR015590 (Aldehyde dehydrogenase), IPR016160 (Aldehyde dehydrogenase, conserved site)
25	col-70	H17B01.2	n/a	chrII 1,471,156	C. elegans COL-70 protein; contains similarity to Interpro domain IPR000694 (Proline-rich region)
26	R11E3.2	R11E3.2	n/a	chrIV 4,773,617	contains similarity to Pfam domain PF00860 Permease family contains similarity to Interpro domain IPR006043 (Xanthine/uracil/vitamin C permease)
27	C14C11.7	C14C11.7	n/a	chrV 5,665,729
28	C38D9.2	C38D9.2	n/a	chrV 17,568,988	contains similarity to Interpro domain IPR001878 (Zinc finger, CCHC-type)
29	F53G2.3	F53G2.3	n/a	chrII 2,480,856
30	F59F5.7	F59F5.7	n/a	chrX 10,563,070	contains similarity to Interpro domain IPR006609 (Region of unknown function DM13, Skeletor)
31	ndx-9	F13H10.2	n/a	chrIV 11,010,995	The ndx-9 gene encodes a member of the NADH pyrophosphatase subfamily of the NUDIX hydrolases.
32	mab-10	R166.1	n/a	chrII 10,532,058	C. elegans MAB-10 protein; contains similarity to Pfam domains PF04905 (NAB conserved region 2 (NCD2)) , PF04904 (NAB conserved region 1 (NCD1)) contains similarity to Interpro domains IPR010993 (Sterile alpha motif homology), IPR006988 (Nab, N-terminal), IPR006989 (Nab, central region)
33	nspb-11	F35C5.10	n/a	chrII 12,907,461	C. elegans NSPB-11 protein ;
34	F33H12.1	F33H12.1	n/a	chrII 2,601,167	contains similarity to Pfam domain PF00533 BRCA1 C Terminus (BRCT) domain contains similarity to Interpro domain IPR001357 (BRCT)
35	clec-21	T07H3.4	n/a	chrII 1,583,563	C. elegans CLEC-21 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
36	Y11D7A.8	Y11D7A.8	n/a	chrIV 9,252,608	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
37	B0222.9	B0222.9	n/a	chrV 9,170,672	contains similarity to Pfam domains PF00941 (FAD binding domain in molybdopterin dehydrogenase) , PF02738 (Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain) , PF00111 (2Fe-2S iron-sulfur cluster binding domain) , PF01799 ([2Fe-2S] binding domain) , PF01315 (Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR001041 (Ferredoxin), IPR002346 (Molybdopterin dehydrogenase, FAD-binding), IPR012675 (Beta-grasp fold, ferredoxin-type), IPR002888 ([2Fe-2S]-binding), IPR016166 (FAD-binding, type 2), IPR006058 (2Fe-2S ferredoxin, iron-sulphur binding site), IPR016169 (CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2), IPR000674 (Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead), IPR008274 (Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding)
38	pkc-1	F57F5.5	n/a	chrV 12,019,252	pkc-1 encodes a serine/threonine protein kinase that is orthologous to mammalian protein kinase C epsilon (PRKCE), a member of the nPKC subgroup of the protein kinase C superfamily; together with UNC-13, PKC-1 may act downstream of goa-1 to modulate phorbol ester-induced stimulation of acetylcholine release at NMJs; PKC-1 positively regulates locomotion, and affects thermotaxis and chemotaxis together with kin-11; PKC-1 is required for regulating several behaviors including sensation of volatile and soluble compounds, osmolarity, and temperature (thermosensation); PKC-1 is also required for phorbolester-induced stimulation of acetylcholine release at neuromuscular junctions; PKC-1 localizes to the processes and cell bodies of approximately 75 sensory neurons and interneurons, and pkc-1 mRNA is detectable at varying levels during larval and adult stages.
39	B0280.2	B0280.2	n/a	chrIII 7,126,452	contains similarity to Interpro domain IPR000697 (EVH1)
40	nhr-143	F59E11.11	n/a	chrV 8,974,032	C. elegans NHR-143 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
41	ubh-1	F46E10.8	n/a	chrV 6,510,664	ubh-1 encodes a putative ubiquitin C-terminal hydrolase orthologous to human UCHL1 (OMIM:191342, mutated in Parkinson disease).
42	T27C4.2	T27C4.2	n/a	chrV 3,729,612
43	ugt-41	F10D2.11	n/a	chrV 7,162,312	C. elegans UGT-41 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
44	T22F3.7	T22F3.7	n/a	chrV 3,599,159	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
45	Y39A1A.20	Y39A1A.20	n/a	chrIII 10,699,807
46	kin-29	F58H12.1	n/a	chrX 2,848,198	kin-29 encodes a serine/threonine kinase with significant homology in the kinase domain to the AMP-activated protein kinase (AMPK) and SNF1 kinases; the AMP-kinase cascade is activated by cellular stresses that deplete ATP; AMP-kinase is believed to protect the mammalian cell by 'switching off' ATP-consuming pathways like fatty acid synthesis, by phosphorylating key regulatory enzymes, and switching on alternative pathways for ATP generation; kin-29 is involved in regulating the expression of chemosensory receptors and entry into the daur pathway; kin-29 also affects body size via interaction with the Sma/Mab pathway and lifespan, with mutants exhibiting a smaller body size and increased life span; a functional KIN-29-GFP fusion protein is expressed in sensory neurons and many other cell types, and localizes to the cytoplasm; under conditions of cellular stress like heat shock and starvation, KIN-29-GFP translocates to the nucleus.
47	cgr-1	T27A10.7	n/a	chrX 3,598,867	C. elegans CGR-1 protein; contains similarity to Pfam domains PF01105 (emp24/gp25L/p24 family/GOLD) , PF00650 (CRAL/TRIO domain) contains similarity to Interpro domains IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal), IPR009038 (GOLD), IPR011074 (Phosphatidylinositol transfer protein-like, N-terminal), IPR000348 (emp24/gp25L/p24)
48	F55A12.8	F55A12.8	n/a	chrI 5,351,713	contains similarity to Pfam domains PF05127 (Putative ATPase (DUF699)) , PF08351 (Domain of unknown function (DUF1726)) contains similarity to Interpro domains IPR013562 (Region of unknown function DUF1726), IPR007807 (Protein of unknown function DUF699, ATPase putative), IPR016181 (Acyl-CoA N-acyltransferase), IPR013324 (RNA polymerase sigma factor, regions 3 and 4)
49	T12G3.4	T12G3.4	n/a	chrIV 12,049,069	contains similarity to Pfam domain PF03088 Strictosidine synthase contains similarity to Interpro domains IPR004141 (Strictosidine synthase), IPR011042 (Six-bladed beta-propeller, TolB-like)
50	F45E4.11	F45E4.11	n/a	chrIV 7,652,864	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)