UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZK1251.9	ZK1251.9	0	chrIV 9,701,830	contains similarity to Pfam domain PF08513 LisH contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR006594 (LisH dimerisation motif), IPR013720 (LisH dimerisation motif, subgroup), IPR015943 (WD40/YVTN repeat-like), IPR016024 (Armadillo-type fold)
2	rpc-1	C42D4.8	n/a	chrIV 7,162,904	C. elegans RPC-1 protein; contains similarity to Pfam domains PF04998 (RNA polymerase Rpb1, domain 5) , PF00623 (RNA polymerase Rpb1, domain 2) , PF04997 (RNA polymerase Rpb1, domain 1) , PF05000 (RNA polymerase Rpb1, domain 4) , PF04983 (RNA polymerase Rpb1, domain 3) contains similarity to Interpro domains IPR006592 (RNA polymerase, N-terminal), IPR007080 (RNA polymerase Rpb1, domain 1), IPR007066 (RNA polymerase Rpb1, domain 3), IPR007083 (RNA polymerase Rpb1, domain 4), IPR000722 (RNA polymerase, alpha subunit), IPR007081 (RNA polymerase Rpb1, domain 5)
3	C34B2.8	C34B2.8	n/a	chrI 10,686,429	contains similarity to Pfam domain PF06212 GRIM-19 protein contains similarity to Interpro domain IPR009346 (GRIM-19)
4	mif-2	C52E4.2	n/a	chrV 11,977,505	C. elegans MIF-2 protein; contains similarity to Pfam domain PF01187 Macrophage migration inhibitory factor (MIF) contains similarity to Interpro domains IPR014347 (Tautomerase), IPR001398 (Macrophage migration inhibitory factor)
5	F21G4.1	F21G4.1	n/a	chrX 9,890,917	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF03137 (Organic Anion Transporter Polypeptide (OATP) family) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR004156 (Organic anion transporter polypeptide OATP), IPR000539 (Frizzled protein), IPR001991 (Sodium:dicarboxylate symporter), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
6	W06H3.3	W06H3.3	n/a	chrV 16,798,543	contains similarity to Pfam domains PF00117 (Glutamine amidotransferase class-I) , PF06418 (CTP synthase N-terminus) contains similarity to Interpro domains IPR000630 (Ribosomal protein S8), IPR017456 (CTP synthase, N-terminal), IPR000991 (Glutamine amidotransferase class-I, C-terminal), IPR004468 (CTP synthase), IPR012998 (Glutamine amidotransferase, class I, active site)
7	F09A5.1	F09A5.1	n/a	chrX 13,132,007	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
8	sec-8	Y106G6H.7	n/a	chrI 10,449,365	The sec-8 gene encodes an ortholog of SEC8 in S. cerevisiae, a component of the exocyst complex required genetically for endocytosis, for normal cellular morphology in the intestine, and for growth at normal rates during development.
9	6R55.2	6R55.2	n/a	chrX 17,713,765
10	D2085.6	D2085.6	n/a	chrII 8,660,679	D2085.6 is orthologous to the human gene CLASS A GLCNAC-INOSITOL PHOSPHOLIPID ASSEMBLY PROTEIN (PIGA; OMIM:311770), which when mutated leads to paroxysmal nocturnal hemoglobinuria.
11	R02F2.7	R02F2.7	n/a	chrIII 5,482,043
12	mrp-3	E03G2.2	n/a	chrX 15,934,560	C. elegans MRP-3 protein; contains similarity to Pfam domains PF00664 (ABC transporter transmembrane region) (2), PF00005 (ABC transporter) (2)contains similarity to Interpro domains IPR003439 (ABC transporter-like), IPR011527 (ABC transporter, transmembrane region, type 1), IPR001140 (ABC transporter, transmembrane region), IPR003593 (AAA+ ATPase, core)
13	T14B4.1	T14B4.1	n/a	chrII 6,739,132
14	ugt-44	F01D4.2	n/a	chrIV 10,470,798	C. elegans UGT-44 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
15	dylt-1	F13G3.4	n/a	chrI 7,300,621	dylt-1 encodes a putative dynein light chain subunit that inhibits DHC-1 in vivo, but is otherwise dispensable for viability; DYLT-1 is paralogous to DYLT-3, and orthologous to human DYNLT1 and DYNLT3 (OMIM: 300302); dylt-1(RNAi) and dylt-1(ok417) both suppress the lethality of conditional dhc-1 mutations, and dylt-1(RNAi) suppresses dhc-1(or195) spindle length and cytokinesis defects as well, indicating that DYLT-1 negatively regulates dynein; in oocytes and early embryos, DYLT-1 is associated with nuclear envelopes and centrosomes, and with meiotic and mitotic spindle poles; like DHC-1 itself, DYLT-1 is strongly mislocalized to centrosomes in dhc-1(or195) animals shifted to nonpermissive temperature.
16	C30F12.2	C30F12.2	n/a	chrI 6,969,030	contains similarity to Pfam domain PF03969 AFG1-like ATPase contains similarity to Interpro domains IPR005654 (AFG1-like ATPase), IPR003593 (AAA+ ATPase, core)
17	F43C9.2	F43C9.2	n/a	chrX 4,788,190	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR008080 (Parvalbumin), IPR003299 (Flagellar calcium-binding protein (calflagin))
18	R03A10.3	R03A10.3	n/a	chrX 15,438,160	contains similarity to Pfam domains PF03473 (MOSC domain) , PF03476 (MOSC N-terminal beta barrel domain) , PF00266 (Aminotransferase class-V) contains similarity to Interpro domains IPR005303 (MOSC, N-terminal beta barrel), IPR005302 (Molybdenum cofactor sulphurase, C-terminal), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR011037 (Pyruvate kinase, beta-barrel-like), IPR000192 (Aminotransferase, class V/Cysteine desulphurase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
19	C03B1.7	C03B1.7	n/a	chrX 6,343,858	contains similarity to Sulfolobus tokodaii DNA double-strand break repair rad50 ATPase.; SW:Q96YR5
20	F26H9.5	F26H9.5	n/a	chrI 9,313,557	contains similarity to Pfam domain PF00266 Aminotransferase class-V contains similarity to Interpro domains IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR000192 (Aminotransferase, class V/Cysteine desulphurase), IPR003248 (Phosphoserine aminotransferase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
21	C35A11.4	C35A11.4	n/a	chrV 5,391,300	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
22	F07A11.5	F07A11.5	n/a	chrII 11,613,153	contains similarity to Pfam domain PF00294 pfkB family carbohydrate kinase contains similarity to Interpro domains IPR011611 (Carbohydrate/purine kinase), IPR011877 (Ribokinase, bacterial), IPR002139 (Ribokinase)
23	F33H2.5	F33H2.5	n/a	chrI 15,009,733	contains similarity to Pfam domains PF00136 (DNA polymerase family B) , PF03104 (DNA polymerase family B, exonuclease domain) , PF08490 (Domain of unknown function (DUF1744)) contains similarity to Interpro domains IPR006055 (Exonuclease), IPR006172 (DNA-directed DNA polymerase, family B), IPR006133 (DNA-directed DNA polymerase, family B, exonuclease), IPR006134 (DNA-directed DNA polymerase, family B, conserved region), IPR013697 (Region of unknown function DUF1744), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
24	lpd-2	C48E7.3	n/a	chrI 6,254,291	C. elegans LPD-2 protein; contains similarity to Interpro domain IPR010916 (TonB box, conserved site)
25	F28A10.10	F28A10.10	n/a	chrII 831,531	contains similarity to Pfam domain PF01467 Cytidylyltransferase contains similarity to Interpro domains IPR004821 (Cytidyltransferase-related), IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold), IPR004820 (Cytidylyltransferase)
26	srm-2	T28H11.3	n/a	chrIV 5,009,723	C. elegans SRM-2 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	C02G6.1	C02G6.1	n/a	chrV 5,878,092	contains similarity to Pfam domains PF00675 (Insulinase (Peptidase family M16)) , PF05193 (Peptidase M16 inactive domain) (2)contains similarity to Interpro domains IPR001431 (Peptidase M16, zinc-binding site), IPR011765 (Peptidase M16, N-terminal), IPR011237 (Peptidase M16, core), IPR007863 (Peptidase M16, C-terminal), IPR011249 (Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)
28	W04B5.1	W04B5.1	n/a	chrIII 2,428,781
29	unc-31	ZK897.1	n/a	chrIV 12,780,334	unc-31 encodes a pleckstrin homology (PH) domain-containing protein that is the C. elegans ortholog of human CADPS/CAPS (calcium-dependent activator protein for secretion OMIM:604667); UNC-31 functions in post-docking calcium-regulated dense-core vesicle fusion that is required for egg laying, locomotion, pharyngeal pumping, and recovery from the dauer larval stage; in addition, UNC-31 functions in the insulin receptor signaling pathway that regulates adult life span where it may control Ca[2+]-regulated secretion of an insulin-like ligand; UNC-31 is not required for synaptic vesicle exocytosis; unc-31::gfp transcriptional reporters are expressed in most, if not all, neurons, vulval muscles, vulval cells, the spermatheca, and secretory cells such as the uterine UV1 cells; UNC-31::GFP translational fusions localize to neuronal cell bodies, axonal projections and to sites of synaptic contact, consistent with other dense-core vesicle proteins.
30	C08B6.2	C08B6.2	n/a	chrV 10,106,583	contains similarity to Rattus norvegicus Adenomatous polyposis coli protein (APC protein).; SW:APC_RAT
31	sfxn-1.5	T04F8.1	n/a	chrX 11,660,570	C. elegans SFXN-1.5 protein; contains similarity to Pfam domain PF03820 Tricarboxylate carrier contains similarity to Interpro domain IPR004686 (Tricarboxylate/iron carrier)
32	cya-2	F59H6.7	n/a	chrII 2,023,091	C. elegans CYA-2 protein; contains similarity to Pfam domain PF00134 Cyclin, N-terminal domain contains similarity to Interpro domains IPR006670 (Cyclin), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR006671 (Cyclin, N-terminal)
33	T23G4.3	T23G4.3	n/a	chrIV 13,686,045	contains similarity to Homo sapiens BAG-family molecular chaperone regulator-4; ENSEMBL:ENSP00000287322
34	H41C03.2	H41C03.2	n/a	chrII 5,851,169	contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domain IPR002921 (Lipase, class 3)
35	E04F6.6	E04F6.6	n/a	chrII 7,198,430	contains similarity to Interpro domain IPR000183 (Orn/DAP/Arg decarboxylase 2)
36	F52C12.3	F52C12.3	n/a	chrIV 1,950,714
37	ddx-23	F01F1.7	n/a	chrIII 5,851,012	C. elegans DDX-23 protein; contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014014 (RNA helicase, DEAD-box type, Q motif), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
38	C45B2.6	C45B2.6	n/a	chrX 6,055,182	contains similarity to Pfam domains PF01734 (Patatin-like phospholipase) , PF00023 (Ankyrin repeat) (3)contains similarity to Interpro domains IPR016035 (Acyl transferase/acyl hydrolase/lysophospholipase), IPR002641 (Patatin), IPR002110 (Ankyrin)
39	hlh-15	C43H6.8	n/a	chrX 2,413,123	C. elegans HLH-15 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
40	F43E2.9	F43E2.9	n/a	chrII 7,359,080
41	fbxa-51	T12B5.1	n/a	chrIII 962,902	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
42	oxi-1	Y39A1C.2	n/a	chrIII 10,862,495	C. elegans OXI-1 protein; contains similarity to Pfam domain PF00632 HECT-domain (ubiquitin-transferase) contains similarity to Interpro domain IPR000569 (HECT)
43	C06E1.3	C06E1.3	n/a	chrIII 8,582,414	contains similarity to Drosophila melanogaster Flybase gene name is mol-PD;; FLYBASE:CG4482
44	duo-3	Y106G6H.12	n/a	chrI 10,467,681	C. elegans DUO-3 protein; contains similarity to Pfam domains PF00443 (Ubiquitin carboxyl-terminal hydrolase) , PF02338 (OTU-like cysteine protease) contains similarity to Interpro domains IPR003323 (Ovarian tumour, otubain), IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)
45	C06B8.7	C06B8.7	n/a	chrV 15,505,052	contains similarity to Pfam domain PF00530 Scavenger receptor cysteine-rich domain contains similarity to Interpro domains IPR002160 (Proteinase inhibitor I3, Kunitz legume), IPR001190 (Speract/scavenger receptor), IPR011050 (Pectin lyase fold/virulence factor), IPR006626 (Parallel beta-helix repeat), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR017448 (Speract/scavenger receptor related)
46	T09B4.9	T09B4.9	n/a	chrI 6,179,413	contains similarity to Pfam domain PF04280 Tim44-like domain contains similarity to Interpro domains IPR007379 (Mitochondrial import inner membrane translocase, subunit Tim44), IPR017303 (Import inner membrane translocase, TIM44 subunit, mitochondria), IPR005682 (Mitochondrial import inner membrane translocase, subunit Tim44, subtype)
47	F56C11.3	F56C11.3	n/a	chrI 182,455	contains similarity to Pfam domain PF04777 Erv1 / Alr family contains similarity to Interpro domain IPR006863 (Erv1/Alr)
48	F23F12.3	F23F12.3	n/a	chrIII 6,504,028	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
49	nlt-1	ZK892.2	n/a	chrII 10,000,661	nlt-1 encodes a member of the SCP-2 sterol transfer family.
50	R04E5.2	R04E5.2	n/a	chrX 8,814,421	R04E5.2 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C01H6.6, C33D12.2, C52D10.12, M02F4.3, and R13G10.4; by orthology with MAM3, R04E5.2 may participate in metal homoeostasis; R04E5.2, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; R04E5.2 has no obvious function in RNAi assays.