UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZK1248.10	ZK1248.10	0	chrII 5,825,597	contains similarity to Pfam domains PF00169 (PH domain) , PF00566 (TBC domain) contains similarity to Interpro domains IPR000195 (RabGAP/TBC), IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	C13B9.3	C13B9.3	n/a	chrIII 6,623,764	C13B9.3 encodes a delta subunit of the coatomer (COPI) complex; in mass RNAi assays, C13B9.3 is required for fertility and general health.
4	scl-27	ZK6.3	n/a	chrV 400,930	C. elegans SCL-27 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR001283 (Allergen V5/Tpx-1 related)
5	F28B3.1	F28B3.1	n/a	chrI 4,946,480	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domains IPR000010 (Proteinase inhibitor I25, cystatin), IPR000873 (AMP-dependent synthetase and ligase)
6	lpd-9	T21C9.5	n/a	chrV 10,579,970	lpd-9 encodes a novel protein conserved amongst C. elegans, C. briggsae, and C. remanei; loss of lpd-9 activity via RNAi indicates that LPD-9 is required for fat storage and for larval growth and development.
7	C56G2.7	C56G2.7	n/a	chrIII 6,340,161	contains similarity to Pfam domain PF04683 Adhesion regulating molecule conserved region contains similarity to Interpro domain IPR006773 (Adhesion regulating molecule)
8	drs-1	B0464.1	n/a	chrIII 9,490,166	drs-1 encodes a putative aspartyl(D) tRNA synthetase
9	F32G8.4	F32G8.4	n/a	chrV 10,559,356	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
10	F52H3.5	F52H3.5	n/a	chrII 10,030,510	contains similarity to Pfam domains PF07719 (Tetratricopeptide repeat) , PF00515 (Tetratricopeptide repeat) (3)contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR008940 (Protein prenyltransferase), IPR001440 (Tetratricopeptide TPR-1), IPR013105 (Tetratricopeptide TPR2), IPR013026 (Tetratricopeptide region)
11	Y47G7B.2	Y47G7B.2	n/a	chrII 2,706,989
12	C08B11.8	C08B11.8	n/a	chrII 8,040,793	contains similarity to Pfam domain PF03155 ALG6, ALG8 glycosyltransferase family contains similarity to Interpro domain IPR004856 (ALG6, ALG8 glycosyltransferase)
13	git-1	F14F3.2	n/a	chrX 10,526,597	C. elegans GIT-1 protein; contains similarity to Pfam domains PF01412 (Putative GTPase activating protein for Arf) , PF00023 (Ankyrin repeat) (2)contains similarity to Interpro domains IPR013724 (Spa2 homology (SHD) of GIT), IPR001164 (Arf GTPase activating protein), IPR002110 (Ankyrin)
14	C17H11.2	C17H11.2	n/a	chrX 8,171,341
15	F33H1.3	F33H1.3	n/a	chrII 10,173,524	contains similarity to Drosophila melanogaster Flybase gene name is CG2685-PA;; FLYBASE:CG2685
16	stdh-3	C06B3.5	n/a	chrV 13,905,299	stdh-3 encodes a putative steroid dehydrogenase orthologous to human HSD17B3 (OMIM:605573, mutated in pseudohermaphroditism), HSD17B12 (OMIM:609574), and HSDL1, and paralogous to LET-767, STDH-1/-2, and STDH-4; STDH-3 has no obvious function in mass RNAi assays.
17	F35E2.8	F35E2.8	n/a	chrI 11,719,340	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
18	nhl-2	F26F4.7	n/a	chrIII 4,896,829	C. elegans NHL-2 protein; contains similarity to Pfam domains PF00097 (Zinc finger, C3HC4 type (RING finger)) , PF00643 (B-box zinc finger) (2), PF01436 (NHL repeat) (4)contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR003649 (B-box, C-terminal), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR000315 (Zinc finger, B-box), IPR001258 (NHL repeat)
19	tag-353	F25D7.2	n/a	chrI 10,401,993	C. elegans TAG-353 protein; contains similarity to Interpro domain IPR000626 (Ubiquitin)
20	tag-229	W09G3.3	n/a	chrI 13,804,628	C. elegans TAG-229 protein; contains similarity to Pfam domain PF08755 Hemimethylated DNA-binding protein YccV like contains similarity to Interpro domain IPR011722 (Hemimethylated DNA-binding region)
21	K06B9.4	K06B9.4	n/a	chrIV 4,192,228
22	srt-64	C03A7.9	n/a	chrV 5,168,964	C. elegans SRT-64 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
23	T23H2.3	T23H2.3	n/a	chrI 6,444,050	contains similarity to Pfam domains PF00271 (Helicase conserved C-terminal domain) , PF00176 (SNF2 family N-terminal domain) contains similarity to Interpro domains IPR000330 (SNF2-related), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
24	F47G9.1	F47G9.1	n/a	chrV 11,325,591	contains similarity to Interpro domain IPR009038 (GOLD)
25	W04G3.5	W04G3.5	n/a	chrX 11,074,823	contains similarity to Pfam domain PF00156 Phosphoribosyl transferase domain contains similarity to Interpro domains IPR005946 (Phosphoribosyl pyrophosphokinase), IPR000836 (Phosphoribosyltransferase)
26	C03H5.2	C03H5.2	n/a	chrII 390,779	C03H5.2 encodes a transporter of UDP-N-acetylglucosamine (UDP-GlcNAc) and UDP-N-acetylgalactosamine (UDP-GalNAc), orthologous to human SLC35A3 (OMIM:605632); CO3H5.2 is redundantly required, with its paralog SRF-3, for normal progression of oocytes through proximal gonads and for normal gonad morphology; C03H5.2 is expressed in many tissues, including pharynx, intestine, pharyngeal gland cells, seam cells, spermatheca, vulva, various muscles, hypodermis, and neurons; C03H5.2 transports both UDP-GlcNAc and UDP-GalNAc independently and simultaneously, with these two molecules neither competing with one another nor being transported as a heterodimer; C03H5.2's two transport activities are genetically separable, since an internally deleted version of C03H5.2 (lacking only 16 residues) retains normal levels of UDP-GlcNAc transport while losing 85-90% of its UDP-GalNAc transport activity; C03H5.2's activity has been experimentally validated through heterologous expression in budding yeast Golgi apparatus, and mutation of C03H5.2 in conserved residues greatly reduces this activity.
27	B0250.5	B0250.5	n/a	chrV 20,491,021	contains similarity to Pfam domain PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase contains similarity to Interpro domains IPR006115 (6-phosphogluconate dehydrogenase, NAD-binding), IPR013328 (Dehydrogenase, multihelical), IPR015815 (3-hydroxyacid dehydrogenase/reductase), IPR011548 (3-hydroxyisobutyrate dehydrogenase), IPR006183 (6-phosphogluconate dehydrogenase), IPR016040 (NAD(P)-binding), IPR002204 (3-hydroxyisobutyrate dehydrogenase-related, conserved site)
28	R01E6.2	R01E6.2	n/a	chrX 13,565,948	contains similarity to Pfam domain PF06394 Pepsin inhibitor-3-like repeated domain contains similarity to Interpro domain IPR010480 (Proteinase inhibitor I33, aspin)
29	hlh-15	C43H6.8	n/a	chrX 2,413,123	C. elegans HLH-15 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
30	C02C2.4	C02C2.4	n/a	chrIII 7,863,860	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
31	mut-15	T01C3.8	n/a	chrV 15,003,779	C. elegans MUT-15 protein ;
32	K10D3.4	K10D3.4	n/a	chrI 7,137,354	contains similarity to Pfam domains PF01683 (EB module) , PF00014 (Kunitz/Bovine pancreatic trypsin inhibitor domain) (5)contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR006150 (Cysteine-rich repeat), IPR006149 (Nematode-specific EB region)
33	cdk-8	F39H11.3	n/a	chrI 8,704,132	cdk-8 encodes a member of the cyclin-dependent serine/threonine protein kinase family orthologous to human CDK8 (OMIM:603184) which functions in transcriptional regulation with the positive regulatory factor cyclin C, is associated with the RNA polymerase II holoenzyme, and may regulate gene-specific activators; CDK-8 also contains a glutamine/asparagine-rich domain; loss of cdk-8 function via RNA-mediated interference (RNAi) results in sterility in the injected hermaphrodite, suggesting that in C. elegans, CDK-8 may play a role in germ-line development.
34	C08B6.7	C08B6.7	n/a	chrV 10,132,247	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
35	F26B1.5	F26B1.5	n/a	chrI 6,309,949	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
36	rpt-2	F29G9.5	n/a	chrV 6,016,841	C. elegans RPT-2 protein; contains similarity to Pfam domain PF00004 ATPase family associated with various cellular activities (AAA) contains similarity to Interpro domains IPR003959 (AAA ATPase, core), IPR003960 (AAA ATPase, conserved site), IPR005937 (26S proteasome subunit P45), IPR003593 (AAA+ ATPase, core)
37	col-128	F12F6.9	n/a	chrIV 11,550,954	C. elegans COL-128 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
38	plc-4	R05G6.8	n/a	chrIV 7,511,060	C. elegans PLC-4 protein; contains similarity to Pfam domains PF00168 (C2 domain) , PF00387 (Phosphatidylinositol-specific phospholipase C, Y domain) , PF09279 (Phosphoinositide-specific phospholipase C, efhand-like) , PF00036 (EF hand) , PF00388 (Phosphatidylinositol-specific phospholipase C, X domain) contains similarity to Interpro domains IPR015359 (Phospholipase C, phosphoinositol-specific, EF-hand-like), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR001192 (Phospholipase C, phosphoinositol-specific, C-terminal (PLC)), IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type), IPR000909 (Phospholipase C, phosphatidylinositol-specific , X region), IPR001711 (Phospholipase C, phosphatidylinositol-specific, Y domain), IPR013841 (Phospholipase C, phosphatidylinositol-specific , X and Y boxes), IPR000008 (C2 calcium-dependent membrane targeting)
39	R04B5.5	R04B5.5	n/a	chrV 10,088,214	contains similarity to Pfam domains PF00107 (Zinc-binding dehydrogenase) , PF08240 (Alcohol dehydrogenase GroES-like domain) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR013149 (Alcohol dehydrogenase, zinc-binding), IPR011032 (GroES-like), IPR013154 (Alcohol dehydrogenase GroES-like), IPR002085 (Alcohol dehydrogenase superfamily, zinc-containing), IPR011597 (GroES-related), IPR016040 (NAD(P)-binding), IPR002328 (Alcohol dehydrogenase, zinc-containing, conserved site)
40	Y38C9A.1	Y38C9A.1	n/a	chrV 112,782	contains similarity to Leishmania major strain Friedlin Proteophosphoglycan ppg4.; TR:Q4FX63
41	cyp-34A5	B0213.10	n/a	chrV 3,956,709	C. elegans CYP-34A5 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
42	ath-1	K04G2.5	n/a	chrI 8,037,923	C. elegans ATH-1 protein; contains similarity to Pfam domain PF02230 Phospholipase/Carboxylesterase contains similarity to Interpro domains IPR003140 (Phospholipase/carboxylesterase), IPR003089 (Alpha/beta hydrolase)
43	fbxa-140	C47B2.1	n/a	chrI 12,961,384	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
44	C14B1.6	C14B1.6	n/a	chrIII 3,716,084	contains similarity to Interpro domain IPR008162 (Inorganic pyrophosphatase)
45	C47E12.3	C47E12.3	n/a	chrIV 10,000,452	contains similarity to Pfam domain PF01532 Glycosyl hydrolase family 47 contains similarity to Interpro domain IPR001382 (Glycoside hydrolase, family 47)
46	tag-72	C25A1.3	n/a	chrI 10,160,921	C. elegans TAG-72 protein; contains similarity to Pfam domains PF03291 (mRNA capping enzyme) , PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) contains similarity to Interpro domains IPR004971 (mRNA capping enzyme, large subunit), IPR016899 (mRNA (guanine-N(7))-methyltransferase), IPR002296 (N6 adenine-specific DNA methyltransferase, N12 class), IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
47	T05E7.1	T05E7.1	n/a	chrI 6,205,413	contains similarity to Pfam domains PF08840 (BAAT / Acyl-CoA thioester hydrolase C terminal) , PF04775 (Acyl-CoA thioester hydrolase / Bile acid-CoA amino acid N-acetyltransferase) contains similarity to Interpro domains IPR006862 (Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase), IPR014940 (BAAT/Acyl-CoA thioester hydrolase C-terminal), IPR016662 (Acyl-CoA thioesterase, long chain)
48	F09C12.6	F09C12.6	n/a	chrII 5,117,137	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
49	B0348.5	B0348.5	n/a	chrV 6,100
50	T01D3.5	T01D3.5	n/a	chrV 13,714,119	contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)