UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	col-19	ZK1193.1	3e-54	chrX 422,242	col-19 encodes a member of the collagen superfamily containing collagen triple helix repeats (20 copies) that is required for normal structure of the alae; expressed during the L2-to-dauer and L4-to-adult molts with strongest expression in adult animals.
2	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
3	col-179	C34F6.3	0.004	chrX 11,201,934	C. elegans COL-179 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR000596 (Cholecystokinin receptor, type A), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
4	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
5	F32D1.2	F32D1.2	n/a	chrV 4,346,245	contains similarity to Pfam domain PF04627 Mitochondrial ATP synthase epsilon chain contains similarity to Interpro domain IPR006721 (ATPase, F1 complex, epsilon subunit, mitochondrial)
6	R13H4.6	R13H4.6	n/a	chrV 11,864,309	contains similarity to Archaeoglobus fulgidus Putative protease La homolog type (EC 3.4.21.-).; SW:O29883
7	C04F12.7	C04F12.7	n/a	chrI 9,696,226	contains similarity to Legionella pneumophila CITA.; TR:O54543
8	col-184	F15A2.1	3e-17	chrX 13,469,888	C. elegans COL-184 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR005404 (Potassium channel, voltage dependent, Kv3.3), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
9	cgh-1	C07H6.5	n/a	chrIII 7,496,952	cgh-1 encodes a putative DEAD-box RNA helicase, orthologous to budding yeast Dhh1p, fission yeast Ste13p, Drosophila ME31B, and human DDX6 (OMIM:600326); CGH-1 inhibits physiological apoptosis in oocytes, keeping it down to a normal level of ~50% in hermaphrodite gonads; independently of apoptosis, CGH-1 is also required for sperm function, oocyte fertilization, and early embryonic cytokinesis; by orthology with budding yeast, CGH-1 is expected to enable decapping-dependent mRNA degradation; CGH-1 is expressed in meiotic germ cells, oocytes, sperm, early embryonic P granules, other unidentified cytoplasmic foci of the gonad core and early embryos, and the germline precursors Z2 and Z3; cgh-1(RNAi) hermaphrodites lose ~100% of their oocytes to physiological apoptosis; gonadal CGH-1 accumulation is suppressed by either glh-1/4 RNAi or gld-1(q485);gld-2(q497) mutations, yet physiological apoptosis (which would normally be elevated by loss of CGH-1) is also abnormally low in these genotypes; cgh-1(RNAi) males have sterile sperm with abnormally short pseudopods; CGH-1 associates with CAR-1, DCAP-2, and CEY-2/3/4 in P granules and cytoplasmic particles of the early embryo; CGH-1 is required for normal CAR-1 localization in early embyros, and binds CAR-1 in an RNA-dependent manner.
10	F31C3.5	F31C3.5	n/a	chrI 15,053,308	contains similarity to Pfam domain PF04128 Partner of SLD five, PSF2 contains similarity to Interpro domains IPR016906 (GINS complex, PSF2 component, subgroup), IPR007257 (GINS complex, Psf2 component)
11	R09E10.6	R09E10.6	n/a	chrIV 10,293,542	contains similarity to Coturnix coturnix Nectinepsin.; TR:Q90351
12	scl-22	T05A10.5	n/a	chrX 10,790,085	C. elegans SCL-22 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
13	col-92	W05B2.6	0.001	chrIII 10,982,591	C. elegans COL-92 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR000596 (Cholecystokinin receptor, type A), IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
14	F47B8.5	F47B8.5	n/a	chrV 14,326,311	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domains IPR002485 (Protein of unknown function DUF13), IPR000694 (Proline-rich region), IPR000976 (Wilm's tumour protein), IPR003071 (Orphan nuclear receptor, HMR type)
15	F47B8.6	F47B8.6	n/a	chrV 14,329,569	contains similarity to Drosophila heteroneura Aminopeptidase N (Fragment).; TR:O61534
16	ttr-14	T05A10.3	n/a	chrX 10,788,525	C. elegans TTR-14 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domains IPR001534 (Transthyretin-like), IPR000533 (Tropomyosin)
17	W02D9.5	W02D9.5	n/a	chrI 12,561,291	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
18	hmg-3	C32F10.5	n/a	chrI 5,816,902	C. elegans HMG-3 protein; contains similarity to Pfam domains PF00505 (HMG (high mobility group) box) , PF08512 (Histone chaperone Rttp106-like) , PF03531 (Structure-specific recognition protein (SSRP1)) contains similarity to Interpro domains IPR013719 (Region of unknown function DUF1747, eukaryote), IPR000969 (Structure-specific recognition protein), IPR000910 (High mobility group box, HMG1/HMG2), IPR009071 (High mobility group box, HMG), IPR000135 (High mobility group box, HMG1/HMG2, subgroup)
19	ZK512.7	ZK512.7	n/a	chrIII 9,138,295
20	iff-1	T05G5.10	n/a	chrIII 9,746,429	iff-1 encodes an eIF-5A homolog that affects fertility and is required for germ cell proliferation and for some P granule components to localize properly; expression is germline specific and mRNA is expressed in the distal region of gonads where germ cells actively proliferate.
21	H11L12.1	H11L12.1	n/a	chrX 17,710,993
22	col-122	T05A1.2	0.0001	chrIV 9,563,877	C. elegans COL-122 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR009143 (Wnt-6 protein), IPR008160 (Collagen triple helix repeat)
23	vha-18	F52E1.10	n/a	chrV 8,412,615	vha-18 encodes an an ortholog of subunit H of the cytoplasmic (V1) domain of vacuolar proton-translocating ATPase (V-ATPase); VHA-18 and VHA-15 are co-orthologs; VHA-18 is a predicted cytosolic stator (stalk) component.
24	ZK632.4	ZK632.4	n/a	chrIII 9,806,382	ZK632.4 is orthologous to the human gene PHOSPHOMANNOSE ISOMERASE (MPI; OMIM:154550), which when mutated leads to disease.
25	him-3	ZK381.1	n/a	chrIV 6,978,215	him-3 encodes a homolog of the S. cerevisiae HOP1 protein which is required for the formation of the synaptonemal complex during meiosis; him-3 is required for synapsis and chiasma formation during meiotic recombination and for chromosome segregation; him-3 mutants show a high frequency of males in the population as well as a high frequency of arrested embryos due to defects in X-chromosome segregation; HIM-3 localizes to the meiotic chromosome associating with both unsynapsed and synapsed chromosomes.
26	Y40H7A.10	Y40H7A.10	n/a	chrIV 15,212,835	contains similarity to Pfam domains PF08246 (Cathepsin propeptide inhibitor domain (I29)) , PF00112 (Papain family cysteine protease) contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR013201 (Proteinase inhibitor I29, cathepsin propeptide), IPR000668 (Peptidase C1A, papain C-terminal)
27	F56C9.3	F56C9.3	n/a	chrIII 7,312,130	contains similarity to Pfam domain PF01545 Cation efflux family contains similarity to Interpro domain IPR002524 (Cation efflux protein)
28	nhr-106	T01G6.4	n/a	chrV 490,539	nhr-106 encodes a nuclear receptor that is most highly conserved amongst nematode species.
29	ivd-1	C02B10.1	n/a	chrIV 5,087,748	The C02B10.1 gene encodes an isovaleryl-CoA dehydrogenase; this function has been verified by both sequence homology and direct biochemical assay.
30	F08H9.2	F08H9.2	n/a	chrV 14,460,857	contains similarity to Interpro domain IPR004064 (EDG-6 sphingosine 1-phosphate receptor)
31	H02I12.1	H02I12.1	n/a	chrIV 11,375,266	H02I12.1 encodes a large (1319-residue) protein with 12 chitin-binding peritrophin-A domains; H02I12.1(RNAi) animals have an osmotically-sensitive embryonic lethal phenotype, perhaps because of defects in chitin and eggshell synthesis; like CEJ-1 and CPG-2, H02I12.1 may participate in eggshell synthesis and early embryonic development; H02I12.1's multiple peritrophin-A domains might enable mechanical cross-linking of chitin.
32	col-94	W05B2.1	0.001	chrIII 10,987,216	C. elegans COL-94 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR000596 (Cholecystokinin receptor, type A), IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
33	ZK856.12	ZK856.12	n/a	chrV 10,214,597	contains similarity to Homo sapiens similar to hypothetical protein FLJ12851; ENSEMBL:ENSP00000301962
34	syp-2	C24G6.1	n/a	chrV 5,537,191	C. elegans SYP-2 protein ;
35	col-159	F57B1.3	0.0002	chrV 13,198,753	C. elegans COL-159 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR001419 (HMW glutenin), IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat), IPR013286 (Annexin, type VII)
36	ZK1251.1	ZK1251.1	n/a	chrIV 9,683,245	contains similarity to Pfam domains PF00808 (Histone-like transcription factor (CBF/NF-Y) and archaeal histone) , PF00125 (Core histone H2A/H2B/H3/H4) contains similarity to Interpro domains IPR009072 (Histone-fold), IPR007125 (Histone core), IPR002119 (Histone H2A), IPR003958 (Transcription factor CBF/NF-Y/archaeal histone)
37	tag-68	F37D6.6	n/a	chrI 10,503,512	C. elegans TAG-68 protein; contains similarity to Pfam domains PF03166 (MH2 domain) , PF03165 (MH1 domain) contains similarity to Interpro domains IPR013019 (MAD homology, MH1), IPR008984 (SMAD/FHA domain), IPR001132 (SMAD domain, Dwarfin-type), IPR017855 (SMAD domain-like), IPR013790 (Dwarfin), IPR003619 (MAD homology 1, Dwarfin-type)
38	plk-3	F55G1.8	n/a	chrIV 7,472,120	C. elegans PLK-3 protein; contains similarity to Pfam domains PF00659 (POLO box duplicated region) (2), PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR017450 (POLO box), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000959 (POLO box duplicated region)
39	ZK938.1	ZK938.1	n/a	chrII 9,830,005	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
40	F17C11.4	F17C11.4	n/a	chrV 10,952,702	contains similarity to Mus musculus Desmoglein 2 precursor.; SW:DSG2_MOUSE
41	him-17	T09E8.2	n/a	chrV 13,178,423	him-17 encodes a protein with no obvious non-nematode homologs that localizes to chromatin in germline nuclei, and that is required for double-stranded break (DSB) formation, chiasmata, crossovers, and genetic recombination during meiosis, but is dispensable for homolog pairing and synapsis, spo-11 germline transcription, or the conversion of DSBs into chiasmata; HIM-17 is also required for normal organization of meiotic stages in the germline, and to promote its orderly transistion from (potentially tumorous) mitosis to meiosis; moreover, HIM-17 is required for normal dimethylation of lysine 9 residues on H3 histones in meiotic prophase chromosomes from early pachytene onward, with null him-17(ok424) mutants showing greatly reduced or delayed dimethylation in both hermaphrodite and male germlines; HIM-17 cooperates with GLP-1 to promote meiotic entry, and with EGO-1 to promote germline viability; HIM-17 has six THAP and THAP-like domains, a domain type also found in CDC-14B, CTB-1, GON-14, LIN-15A, LIN-15B, and LIN-36, along with ~100 other proteins such as Drosophila P element transposase and human nuclear proapoptotic factor THAP1; missense or truncating mutations of HIM-17's THAP and THAP-like domains cause partial loss of function, implying that the domains collectively and partially contribute to HIM-17 activity; of the C. elegans genes encoding THAP or THAP-like domains, at least four (lin-15A, lin-15B, lin-36, and him-17) interact genetically with lin-35/Rb.
42	ugt-58	F35H8.6	n/a	chrII 9,585,502	C. elegans UGT-58 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
43	sss-1	F32B6.5	n/a	chrIV 9,893,216	C. elegans SSS-1 protein ;
44	nspd-1	ZK484.8	n/a	chrI 6,097,668	C. elegans NSPD-1 protein; contains similarity to Pfam domain PF05611 Caenorhabditis elegans protein of unknown function (DUF780) contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR008498 (Protein of unknown function DUF780, Caenorhabditis species)
45	col-62	C15A11.6	0.0000000006	chrI 7,403,843	C. elegans COL-62 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat), IPR013286 (Annexin, type VII)
46	col-80	C09G5.5	0.00000000009	chrII 10,707,668	C. elegans COL-80 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat), IPR013286 (Annexin, type VII)
47	C46A5.6	C46A5.6	n/a	chrIV 7,761,969
48	F29C4.6	F29C4.6	n/a	chrIV 120,551	contains similarity to Pfam domain PF01171 PP-loop family contains similarity to Interpro domains IPR011063 (PP-loop), IPR012089 (PP-loop ATPase, YdaO-related), IPR000541 (Protein of unknown function UPF0021), IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold)
49	nspd-4	T23B7.1	n/a	chrII 4,842,734	C. elegans NSPD-4 protein; contains similarity to Pfam domain PF05611 Caenorhabditis elegans protein of unknown function (DUF780) contains similarity to Interpro domain IPR008498 (Protein of unknown function DUF780, Caenorhabditis species)
50	F30A10.4	F30A10.4	n/a	chrI 9,485,166	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)