UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZK1053.3	ZK1053.3	0	chrI 13,248,255	contains similarity to Interpro domain IPR011008 (Dimeric alpha-beta barrel)
2	cyld-1	F40F12.5	n/a	chrIII 9,904,526	F40F12.5 encodes an ortholog of human CYLD1 (OMIM:605018, mutated in cylindromatosis); CYLD1 binds several members of the NF-kappaB signalling pathway, and can deubiquitinate target proteins.
3	W10D9.2	W10D9.2	n/a	chrII 451,150	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
4	clec-92	Y52B11A.5	n/a	chrI 11,016,484	C. elegans CLEC-92 protein; contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
5	lon-2	C39E6.1	n/a	chrX 4,743,993	lon-2 encodes a member of the glypican family of heparan sulfate proteoglycans; during development, lon-2 activity is required in the hypodermis for negative regulation of the DBL-1/BMP signaling pathway that regulates body length; genetic analyses indicate that lon-2 functions upstream of dbl-1, and in vitro studies show that LON-2 can bind mammalian BMP2, suggesting that LON-2 may directly interact with DBL-1 to negatively regulate DBL-1/BMP signaling; in addition to expression in hypodermis, LON-2 is expressed strongly in the intestine, particularly the anterior and posterior cells; LON-2 localizes to the cell surface.
6	F52C9.5	F52C9.5	n/a	chrIII 5,304,230	contains similarity to Pfam domain PF00024 PAN domain contains similarity to Interpro domains IPR000884 (Thrombospondin, type I), IPR003609 (Apple-like), IPR003014 (N/apple PAN)
7	srh-7	K09D9.7	n/a	chrV 4,009,007	C. elegans SRH-7 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
8	F18A11.3	F18A11.3	n/a	chrII 13,036,522	contains similarity to Candida albicans Multidrug resistance protein CDR2.; SW:CDR2_CANAL
9	Y62H9A.10	Y62H9A.10	n/a	chrX 11,901,221	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
10	D1065.3	D1065.3	n/a	chrV 4,060,947	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
11	R07B1.6	R07B1.6	n/a	chrX 9,867,228	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
12	R06B10.2	R06B10.2	n/a	chrIII 975,911	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR003125 (Protein of unknown function WSN)
13	T21B10.3	T21B10.3	n/a	chrII 8,936,627	contains similarity to Homo sapiens Conserved hypothetical protein; VG:OTTHUMP00000076919
14	F20D1.8	F20D1.8	n/a	chrX 14,996,828	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
15	R107.2	R107.2	n/a	chrIII 9,044,850	contains similarity to Pfam domain PF01256 Carbohydrate kinase contains similarity to Interpro domain IPR000631 (Carbohydrate kinase)
16	C36C5.15	C36C5.15	n/a	chrV 3,168,358	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
17	tsp-18	F59G1.2	n/a	chrII 5,905,416	C. elegans TSP-18 protein; contains similarity to Interpro domain IPR008952 (Tetraspanin)
18	Y56A3A.5	Y56A3A.5	n/a	chrIII 11,889,625	contains similarity to Pfam domain PF01425 Amidase contains similarity to Interpro domains IPR000120 (Amidase signature enzyme), IPR000504 (RNA recognition motif, RNP-1)
19	W04A4.4	W04A4.4	n/a	chrI 13,676,809	contains similarity to Pfam domain PF00648 Calpain family cysteine protease contains similarity to Interpro domain IPR001300 (Peptidase C2, calpain)
20	srx-23	F31F4.2	n/a	chrV 683,114	C. elegans SRX-23 protein ;
21	F56C9.8	F56C9.8	n/a	chrIII 7,317,655
22	math-5	C16C4.10	n/a	chrII 1,882,210	C. elegans MATH-5 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
23	lgc-1	T05B4.1	n/a	chrV 4,136,911	C. elegans LGC-1 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR002394 (Nicotinic acetylcholine receptor, N-terminal), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
24	M01H9.2	M01H9.2	n/a	chrIV 4,461,106	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR002350 (Proteinase inhibitor I1, Kazal), IPR001368 (TNFR/CD27/30/40/95 cysteine-rich region), IPR003582 (Metridin-like ShK toxin)
25	C07A4.3	C07A4.3	n/a	chrX 10,175,118	contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
26	K01A11.2	K01A11.2	n/a	chrIII 3,426,861	contains similarity to Xenopus laevis LOC495955 protein.; TR:Q5PQ79
27	srxa-15	Y44A6B.2	n/a	chrV 20,638,710	C. elegans SRXA-15 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
28	F58D12.3	F58D12.3	n/a	chrV 14,062,015	contains similarity to Interpro domain IPR009091 (Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)
29	F32B5.2	F32B5.2	n/a	chrI 2,698,698
30	pha-2	M6.3	n/a	chrX 635,373	pha-2 encodes a homeodomain protein that is orthologous to vertebrate Hex proteins required for the development of B lymphocytes and organs derived from foregut endoderm; in C. elegans, pha-2 is essential for proper development and morphogenesis of the pm5 pharyngeal muscles cells during late stages of embryogenesis; in regulating pm5 fate specification, PHA-2 appears to act downstream of the organ identity factor PHA-4, and upstream of ceh-22, whose expression it may negatively regulate in pm5; a rescuing PHA-2::GFP reporter is expressed in pharyngeal cells, intestinal-rectal cells, and postembryonic head neurons.
31	cof-2	C48E7.5	n/a	chrI 6,251,698	cof-2 encodes a homolog of human GLC1A, which when mutated leads to glaucome primary open angle (OMIM:137750)
32	srbc-82	C31A11.4	n/a	chrV 16,301,000	C. elegans SRBC-82 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
33	C24A8.1	C24A8.1	n/a	chrX 4,323,582	C24A8.1 encodes an homolog of mammalian D2 or D3 dopamine receptors, and a paralog of DOP-2/-3; C24A8.1 is expressed in the nervous system; because of its paralogy, C24A8.1 might act redundantly with DOP-2 to promote the basal slowing response to bacterial feeding, or it might account for the residual response to excess dopamine seen in triple dop-1/-2/-3 mutants; but C24A8.1 otherwise has no obvious function in RNAi assays of brood size, egg laying, pharyngeal pumping, locomotion, or male mating.
34	F08D12.12	F08D12.12	n/a	chrII 2,784,540	contains similarity to Homo sapiens hypothetical protein; VG:OTTHUMP00000024537
35	F22E5.12	F22E5.12	n/a	chrII 2,646,586	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
36	Y75B8A.6	Y75B8A.6	n/a	chrIII 12,127,086	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
37	F18H3.1	F18H3.1	n/a	chrX 13,520,521	contains similarity to Pfam domain PF00622 SPRY domain contains similarity to Interpro domains IPR001870 (B302, (SPRY)-like), IPR003877 (SPla/RYanodine receptor SPRY)
38	qui-1	Y45F10B.10	n/a	chrIV 13,568,114	The qui-1 gene encodes a protein of unknown function that contains several WD-40 domains.
39	F42G2.6	F42G2.6	n/a	chrII 2,428,176	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR000533 (Tropomyosin), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
40	F58F9.1	F58F9.1	n/a	chrIV 6,251,691	contains similarity to Pfam domain PF00268 Ribonucleotide reductase, small chain contains similarity to Interpro domains IPR012348 (Ribonucleotide reductase-related), IPR000358 (Ribonucleotide reductase), IPR009078 (Ferritin/ribonucleotide reductase-like)
41	K04A8.3	K04A8.3	n/a	chrV 6,559,849
42	K09E2.2	K09E2.2	n/a	chrX 8,677,297
43	F23B2.7	F23B2.7	n/a	chrIV 9,151,248	contains similarity to Homo sapiens similar to Cylicin I (Multiple-band polypeptide I); ENSEMBL:ENSP00000331556
44	pqn-2	AC3.4	n/a	chrV 10,383,199	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
45	T27A8.5	T27A8.5	n/a	chrX 16,065,286	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
46	che-12	B0024.8	n/a	chrV 10,303,399	che-12 encodes a conserved protein that contains at least seven predicted HEAT repeats; CHE-12 activity is required continuously in sensory neurons for formation of distal ciliary segments and thus, for normal sensory cilium morphology and function and chemotaxis to a subset of attractants, including sodium chloride; a che-12::gfp promoter fusion is expressed in the two phasmid neurons and the subset of amphid neurons that contain relatively simple cilia; a CHE-12::GFP protein localizes to cilia in a manner suggesting that it requires intraflagellar transport for proper localization, but is unlikely to be a core IFT particle component; che-12 expression in ciliated neurons is dependent upon the presence of the DAF-19 RFX transcription factor.
47	C01A2.2	C01A2.2	n/a	chrI 13,397,863	contains similarity to Streptomyces coelicolor Putative sugar transporter integral membrane protein.; TR:Q9K489
48	T24C2.3	T24C2.3	n/a	chrX 14,544,021	contains similarity to Arabidopsis thaliana F25I16.10 protein.; TR:Q9FZ78
49	C18D11.1	C18D11.1	n/a	chrIII 11,818,072	contains similarity to Sporobolus stapfianus Hypothetical protein.; TR:O04820
50	srg-39	T19C4.2	n/a	chrV 11,151,861	C. elegans SRG-39 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)