UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	srw-113	ZK1037.9	0	chrV 15,333,837	C. elegans SRW-113 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	elks-1	F42A6.9	n/a	chrIV 3,346,268	elks-1 encodes the C. elegans homolog of the vertebrate ELKS (glutamine, leucine, lysine, and serine-rich) proteins; although loss of elks-1 activity results in no obvious developmental or behavioral abnormalities, the ELKS-1 C-terminus interacts with the PDZ domain of UNC-10/RIM in vitro, and in vivo each protein appears to play a nonessential role in localizing the other to the presynaptic active zone; in addition to the active zone, ELKS-1 also localizes to the pharyngeal basal lamina.
4	ZK1037.1	ZK1037.1	n/a	chrV 15,311,784	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
5	C35C5.2	C35C5.2	n/a	chrX 11,539,654	contains similarity to Pfam domains PF04389 (Peptidase family M28) , PF02225 (PA domain) , PF04253 (Transferrin receptor-like dimerisation domain) contains similarity to Interpro domains IPR007365 (Transferrin receptor-like, dimerisation), IPR007484 (Peptidase M28), IPR003137 (Protease-associated PA)
6	nhr-111	F44G3.9	n/a	chrV 16,123,891	nhr-111 encodes a member of the nuclear receptor superfamily; by homology, NHR-111 is predicted to function as a ligand-dependent transcriptional regulator, but as loss of nhr-111 activity via large-scale RNAi screens does not result in any abnormalities, the precise role of NHR-111 in C. elegans development and/or behavior is not yet known; an nhr-111 reporter construct is expressed in embryos and early larvae in a pair of neurons in the ventral ganglion of the head and in two cells that may be the somatic gonad precursors.
7	M01G12.7	M01G12.7	n/a	chrI 12,115,167	contains similarity to Arabidopsis thaliana Hypothetical protein.; TR:Q9LZ50
8	C40H1.3	C40H1.3	n/a	chrIII 9,328,239	contains similarity to Homo sapiens Protein; VG:OTTHUMP00000003630
9	T05A6.5	T05A6.5	n/a	chrII 7,824,034	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
10	xnp-1	B0041.7	n/a	chrI 4,668,742	xnp-1 encodes an ATP-dependent DNA helicase of the SNF2 family that is orthologous to human XNP/ATR-X, which is associated with a number of X-linked mental retardation syndromes; in C. elegans, xnp-1 activity is required at high temperatures for embryogenesis, somatic gonad development, fertility, and vulval morphogenesis; in addition, animals doubly mutant for xnp-1 and lin-35/Rb, hpl-2/HP1, or nucleosome remodelling and histone deacetylase (NuRD) complex members such as lin-53 and let-418, display larval arrest with growth cessation but continued cell proliferation; xnp-1 is also required, with lin-35/Rb and hpl-2/HP1, for proper regulation of transgene expression; xnp-1 mRNA, detectable in embryos and the germline by in situ hybridization, is expressed at highest levels in embryos with decreasing levels seen in successive larval stages; xnp-1 transcriptional reporter fusions exhibit strong expression beginning at mid-embryogenesis but fading by embryonic morphogenesis; at hatching, expression is observed in all dividing cells including the P lineage, and at later larval stages expression is observed in the vulval precursor cells.
11	str-207	F26G5.4	n/a	chrV 4,952,370	C. elegans STR-207 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
12	nhr-159	C17E7.7	n/a	chrV 3,876,286	C. elegans NHR-159 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
13	str-63	C17B7.1	n/a	chrV 3,352,167	C. elegans STR-63 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
14	Y45G12C.11	Y45G12C.11	n/a	chrV 2,551,494	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domain IPR005049 (Protein of unknown function DUF288)
15	str-204	F10D2.1	n/a	chrV 7,160,334	C. elegans STR-204 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
16	F14F9.6	F14F9.6	n/a	chrV 5,148,306
17	B0496.1	B0496.1	n/a	chrIV 7,446,888	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ), IPR000210 (BTB/POZ-like)
18	srd-51	F15A2.3	n/a	chrX 13,483,631	C. elegans SRD-51 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like)
19	F13G3.10	F13G3.10	n/a	chrI 7,313,972	contains similarity to Interpro domain IPR010989 (t-SNARE)
20	K07C11.10	K07C11.10	n/a	chrV 8,226,436	contains similarity to Homo sapiens hypothetical protein isoform 1; ENSEMBL:ENSP00000381337
21	him-14	ZK1127.11	n/a	chrII 7,067,448	him-14 encodes a germline-specific member of the MutS family of DNA mismatch repair (MMR) proteins that is orthologous to human MSH4 and Saccharomyces cerevisiae Msh4p; during the pachytene stage of meiosis, HIM-14 activity is required for promoting crossing over between homologous chromosomes and thus, for chiasmata formation and proper chromosome segregation; in contrast, HIM-14 activity does not appear to be required for mismatch repair, nor for chromosome pairing or synapsis; him-14 mRNA expression is detected exclusively in the germline.
22	Y75B8A.31	Y75B8A.31	n/a	chrIII 12,353,159	contains similarity to Homo sapiens Isoform 1 of UPF0528 protein C5orf21 precursor; ENSEMBL:ENSP00000265139
23	R10D12.6	R10D12.6	n/a	chrV 13,949,458	contains similarity to Pfam domain PF01679 Uncharacterized protein family UPF0057 contains similarity to Interpro domain IPR000612 (Protein of unknown function UPF0057)
24	T26E4.1	T26E4.1	n/a	chrV 15,780,361	contains similarity to Pfam domain PF01030 (Receptor L domain)
25	T09F5.2	T09F5.2	n/a	chrV 15,151,275	contains similarity to Saccharomyces cerevisiae cell wall mannoprotein; SGD:YOR009W
26	srx-19	T05A12.1	n/a	chrIV 6,874,033	C. elegans SRX-19 protein ;
27	Y54G9A.1	Y54G9A.1	n/a	chrII 13,700,041	contains similarity to Carabus linnei NADH dehydrogenase subunit 5 (Fragment).; TR:O79584
28	C46E10.9	C46E10.9	n/a	chrII 3,728,602	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
29	R119.2	R119.2	n/a	chrI 370,004	contains similarity to Pfam domain PF00557 metallopeptidase family M24 contains similarity to Interpro domains IPR000994 (Peptidase M24, catalytic core), IPR001714 (Peptidase M24, methionine aminopeptidase)
30	dod-20	B0554.6	n/a	chrV 423,333	C. elegans DOD-20 protein; contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
31	srv-6	C52B9.5	n/a	chrX 4,258,053	C. elegans SRV-6 protein ;
32	Y59C2A.1	Y59C2A.1	n/a	chrII 2,210,488	contains similarity to Pfam domain PF00246 Zinc carboxypeptidase contains similarity to Interpro domains IPR000834 (Peptidase M14, carboxypeptidase A), IPR009020 (Proteinase inhibitor, propeptide), IPR000276 (GPCR, rhodopsin-like)
33	T20D4.6	T20D4.6	n/a	chrV 3,411,676	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
34	D2089.3	D2089.3	n/a	chrII 10,663,519	contains similarity to Homo sapiens hypothetical protein LOC150383; ENSEMBL:ENSP00000325301
35	srw-69	F18E3.5	1e-25	chrV 7,428,134	C. elegans SRW-69 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
36	uvt-3	C42D8.3	n/a	chrX 5,090,152	C. elegans UVT-3 protein; contains similarity to Pfam domain PF03630 Fumble contains similarity to Interpro domains IPR002791 (Protein of unknown function DUF89), IPR015844 (Pantothenate kinase, acetyl-CoA regulated, two-domain type), IPR011602 (Fumble)
37	F44A2.2	F44A2.2	n/a	chrV 9,319,570	contains similarity to Pfam domains PF02214 (K+ channel tetramerisation domain) , PF07885 (Ion channel) , PF00520 (Ion transport protein) contains similarity to Interpro domains IPR005821 (Ion transport), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003971 (Potassium channel, voltage dependent, Kv9), IPR003968 (Potassium channel, voltage dependent, Kv), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation), IPR003091 (Voltage-dependent potassium channel), IPR013099 (Ion transport 2), IPR003974 (Potassium channel, voltage dependent, Kv3)
38	srab-25	ZK697.7	n/a	chrV 1,740,043	C. elegans SRAB-25 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF03125 (C. elegans Sre G protein-coupled chemoreceptor) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000344 (Nematode chemoreceptor, Sra)
39	F31A3.5	F31A3.5	n/a	chrX 17,558,148	contains similarity to Interpro domain IPR000694 (Proline-rich region)
40	ZK816.3	ZK816.3	n/a	chrX 3,348,370
41	mdf-1	C50F4.11	n/a	chrV 9,542,977	mdf-1 encodes a coiled-coil domain-containing protein that is orthologous to the Saccharomyces cerevisiae mitotic spindle checkpoint protein Mad1p; consistent with a role as a checkpoint protein, MDF-1 is required in C. elegans for mitotic genome stability and hence, long-term survival and fertility; in vitro, MDF-1 interacts with MDF-2, the C. elegans Mad2p ortholog.
42	F19B10.6	F19B10.6	n/a	chrII 3,663,696
43	srg-22	Y25C1A.10	n/a	chrII 3,092,472	C. elegans SRG-22 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
44	K06A1.1	K06A1.1	n/a	chrII 6,455,658	K06A1.1 encodes an AP-2-like transcription factor.
45	Y62H9A.3	Y62H9A.3	n/a	chrX 11,879,462	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR000480 (Glutelin)
46	srh-74	C45B11.4	n/a	chrV 11,047,962	C. elegans SRH-74 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
47	ceh-30	C33D12.7	n/a	chrX 3,064,554	ceh-30 encodes a homeodomain protein most similar to Drosophila and mammalian BarH1 (OMIM:605211) which function in neuronal cell fate determination; the precise biological role of CEH-30 in C. elegans development and/or behavior is not yet known.
48	srx-122	F35F10.8	n/a	chrV 3,296,984	C. elegans SRX-122 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
49	K03H6.4	K03H6.4	n/a	chrIV 1,519,644
50	scl-21	Y43F8B.5	n/a	chrV 19,495,187	C. elegans SCL-21 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR001283 (Allergen V5/Tpx-1 related)