UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	lgc-37	ZC482.5	0	chrIII 12,789,021	ZC482.5 is orthologous to the human gene GAMMA-AMINOBUTYRIC ACID A RECEPTOR GAMMA 2 (GABRG2; OMIM:137164), which when mutated leads to disease.
2	odr-3	C34D1.3	n/a	chrV 13,248,189	odr-3 encodes a G protein alpha subunit; odr-3 activity is required for normal chemotaxis, odorant avoidance, and nociceptive function as well as cilium morphogenesis in chemosensory neurons; an ODR-3::GFP is expressed in five pairs of sensory neurons AWA, AWB, AWC, ASH, and ADF; the AWC neurons consistently express GFP most strongly, while the AWB neurons express at lower levels and the AWA, ASH, and ADF neurons express only weakly; in AWC neurons, ODR-3::GFP localizes to cilia which have a characteristic wing-shaped morphology.
3	F47F2.3	F47F2.3	n/a	chrX 3,894,817	contains similarity to Interpro domain IPR013032 (EGF-like region, conserved site)
4	aqp-6	C32C4.2	n/a	chrV 10,651,251	apq-6 encodes an aquaporin whose expression in Xenopus oocytes increases water permeability five- to seven-fold; aqp-6 has no function in mass RNAi assays, perhaps reflecting genetic redundancy with its paralogs AQP-4 and AQP-5; AQP-6 is expressed in the cilia and cell bodies of IL1 sensory neurons; AQP-6 is orthologous to human AQP8 (OMIM:603750).
5	C03H5.7	C03H5.7	n/a	chrII 381,414	contains similarity to Interpro domains IPR001991 (Sodium:dicarboxylate symporter), IPR001958 (Tetracycline resistance protein, TetA)
6	F15G9.2	F15G9.2	n/a	chrX 9,713,365	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IAW6
7	C18D1.2	C18D1.2	n/a	chrII 10,057,912	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR008075 (Lipocalin-1 receptor), IPR016196 (MFS general substrate transporter)
8	C15B12.3	C15B12.3	n/a	chrX 6,467,380
9	T20D4.5	T20D4.5	n/a	chrV 3,414,578	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
10	rgs-1	C05B5.7	n/a	chrIII 10,015,270	rgs-1 encodes a regulator of G protein signaling; by homology, RGS-1 is predicted to function as a GTPase-activating protein for heterotrimeric G-protein alpha-subunits, and in vitro RGS-1 can stimulate the GTPase activity of purified GOA-1; in vivo, rgs-1 appears to function redundantly with rgs-2 to regulate egg-laying behavior when animals are refed following starvation; rgs-1 is expressed in most or all neurons.
11	ZK896.1	ZK896.1	n/a	chrIV 12,874,056	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
12	srx-136	F09F3.12	n/a	chrV 13,858,174	C. elegans SRX-136 protein ;
13	C17H11.1	C17H11.1	n/a	chrX 8,177,329	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000565 (DNA topoisomerase, type IIA, subunit B), IPR000276 (GPCR, rhodopsin-like)
14	C50E3.8	C50E3.8	n/a	chrV 7,598,180
15	str-253	F41B5.8	n/a	chrV 2,253,703	C. elegans STR-253 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002091 (Aromatic amino acid permease)
16	C01G5.4	C01G5.4	n/a	chrIV 6,533,692	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domains IPR003125 (Protein of unknown function WSN), IPR001399 (VP6 blue-tongue virus inner capsid protein)
17	moe-3	F32A11.6	n/a	chrII 13,163,070	moe-3 encodes a CCCH tandem zinc finger (TZF) protein; while loss of moe-3 activity via RNAi alone results in no obvious abnormalities, animals triply mutant for moe-3, oma-1, and oma-2 demonstrate oocyte maturation defects, indicating that these genes likely function redundantly during germline development; in situ hybridization experiments indicate that moe-3 mRNA expression is relatively weak and restricted to the distal region of the gonad; based upon its sequence similarity to other TZF proteins, such as MEX-5 and POS-1, the product of MOE-3 is predicted to function as an RNA-binding protein.
18	F15A8.1	F15A8.1	n/a	chrX 4,441,526
19	F40G9.8	F40G9.8	n/a	chrIII 164,235
20	adt-1	C02B4.1	n/a	chrX 12,683,974	The adt-1 gene encodes a metalloproteinase with disintegrin-like and metalloproteinase with thrombospondin type I motifs (ADAMTS) that is required for male tail morphogenesis.
21	F44A2.7	F44A2.7	n/a	chrV 9,322,227
22	Y43F8C.11	Y43F8C.11	n/a	chrV 19,670,774	contains similarity to Mus sp Interleukin-3 receptor beta subunit (Fragment).; TR:Q64130
23	str-252	C06B3.9	n/a	chrV 13,917,252	C. elegans STR-252 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR008365 (Prostanoid receptor), IPR003002 (7TM chemoreceptor, subfamily 1)
24	srg-14	F26B1.6	n/a	chrI 6,313,673	C. elegans SRG-14 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
25	F35E2.1	F35E2.1	n/a	chrI 11,739,734	contains similarity to Pfam domain PF06681 Protein of unknown function (DUF1182) contains similarity to Interpro domains IPR002091 (Aromatic amino acid permease), IPR010601 (Protein of unknown function DUF1182)
26	W03A5.1	W03A5.1	n/a	chrIII 5,410,601	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR001452 (Src homology-3), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
27	K04F1.11	K04F1.11	n/a	chrV 1,660,979	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
28	clec-45	F07C4.2	n/a	chrV 7,638,344	C. elegans CLEC-45 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
29	Y12A6A.2	Y12A6A.2	n/a	chrX 13,619,323	contains similarity to Phaseolus lunatus Double-headed bowman-birk inhibitor (Fragment).; TR:Q941H3
30	F20D1.3	F20D1.3	n/a	chrX 14,977,334	contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR000018 (P2Y4 purinoceptor), IPR015915 (Kelch-type beta propeller)
31	M05B5.6	M05B5.6	n/a	chrI 7,184,379	contains similarity to Homo sapiens Transient receptor potential cation channel subfamily A member 1; ENSEMBL:ENSP00000262209
32	srf-3	M02B1.1	n/a	chrIV 12,852,213	C. elegans SRF-3 protein; contains similarity to Pfam domains PF08449 (UAA transporter family) , PF04142 (Nucleotide-sugar transporter) contains similarity to Interpro domains IPR004689 (UDP-galactose transporter), IPR013657 (UAA transporter), IPR007271 (Nucleotide-sugar transporter)
33	srb-17	F01D4.7	n/a	chrIV 10,455,510	C. elegans SRB-17 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF03125 (C. elegans Sre G protein-coupled chemoreceptor) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000344 (Nematode chemoreceptor, Sra)
34	clec-10	C03H5.1	n/a	chrII 403,400	C. elegans CLEC-10 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR002345 (Lipocalin), IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
35	sre-44	W07G1.2	n/a	chrII 13,950,633	C. elegans SRE-44 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
36	C50E3.7	C50E3.7	n/a	chrV 7,595,623	contains similarity to Interpro domain IPR001499 (Fungal pheromone STE3 GPCR)
37	F10G2.7	F10G2.7	n/a	chrV 7,335,453	contains similarity to Pfam domain PF06852 Protein of unknown function (DUF1248) contains similarity to Interpro domain IPR009658 (Protein of unknown function DUF1248)
38	C17H1.6	C17H1.6	n/a	chrI 13,131,624	contains similarity to Danio rerio Arginine and glutamate-rich protein 1-B.; SW:Q6P5L7
39	T05A10.6	T05A10.6	n/a	chrX 10,793,737	contains similarity to Interpro domain IPR014044 (SCP-like extracellular)
40	C01A2.6	C01A2.6	n/a	chrI 13,382,132	contains similarity to Dictyostelium discoideum Putative uncharacterized protein.; TR:Q54BK4
41	CD4.5	CD4.5	n/a	chrV 5,590,729
42	T25E4.2	T25E4.2	n/a	chrII 5,581,240
43	K06A9.2	K06A9.2	n/a	chrX 1,538,348	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
44	Y47D3B.3	Y47D3B.3	n/a	chrIII 11,400,137	contains similarity to Homo sapiens Low-density lipoprotein receptor-related protein 2 precursor; ENSEMBL:ENSP00000263816
45	F53B1.3	F53B1.3	n/a	chrX 2,106,394
46	npr-9	ZK455.3	n/a	chrX 11,330,259	C. elegans NPR-9 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002286 (P2 purinoceptor), IPR001556 (Bombesin receptor), IPR009144 (Thyrotropin-releasing hormone receptor), IPR000586 (Somatostatin receptor), IPR000405 (Galanin receptor), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
47	F37C12.1	F37C12.1	n/a	chrIII 7,186,028	contains similarity to Pfam domain PF04502 Family of unknown function (DUF572) contains similarity to Interpro domain IPR007590 (Protein of unknown function DUF572)
48	F11G11.4	F11G11.4	n/a	chrII 4,861,326
49	srh-192	ZC132.7	n/a	chrV 4,313,561	C. elegans SRH-192 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
50	F49D11.2	F49D11.2	n/a	chrI 10,922,443	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)