UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	gab-1	ZC482.1	0	chrIII 12,775,682	gab-1 encodes a gamma-aminobutyric acid (GABA) receptor beta-like subunit with both the neurotransmitter-gated ion-channel ligand binding and transmembrane domains; gab-1 can form a GABA-responsive channel when co-expressed with alpha/gamma type subunits in a heterologous expression system; experiments with gab-1 indicate that GABA receptors are involved in the mechanism of resistance to the widely used broad-spectrum anthelmintic drug Ivermectin.
2	R06C1.6	R06C1.6	n/a	chrI 11,950,040	contains similarity to Saccharomyces cerevisiae CCR4 Associated Factor 120 kDa; SGD:YNL278W
3	ZC239.3	ZC239.3	n/a	chrII 3,216,335	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
4	str-66	Y73C8C.5	n/a	chrV 3,103,680	C. elegans STR-66 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
5	F33E2.6	F33E2.6	n/a	chrI 12,589,287	contains similarity to Interpro domains IPR006030 (Molluscan rhodopsin C-terminal tail), IPR000694 (Proline-rich region)
6	mif-3	F13G3.9	n/a	chrI 7,313,193	C. elegans MIF-3 protein; contains similarity to Pfam domain PF01187 Macrophage migration inhibitory factor (MIF) contains similarity to Interpro domains IPR014347 (Tautomerase), IPR001398 (Macrophage migration inhibitory factor)
7	F02E11.2	F02E11.2	n/a	chrII 3,267,119
8	flp-17	C52D10.11	n/a	chrIV 17,191,022	C. elegans FLP-17 protein; contains similarity to Pfam domain PF01581 FMRFamide related peptide family
9	Y57A10B.1	Y57A10B.1	n/a	chrII 12,362,805	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
10	M163.1	M163.1	n/a	chrX 14,503,087	contains similarity to Mus musculus Adapter-related protein complex 3 beta 1 subunit (Beta-adaptin 3A)s(AP-3 complex beta-3A subunit) (Beta-3A-adaptin).; SW:A3B1_MOUSE
11	nhr-39	F44A2.4	n/a	chrV 9,303,947	C. elegans NHR-39 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
12	R05G6.1	R05G6.1	n/a	chrIV 7,539,920
13	T16H12.9	T16H12.9	n/a	chrIII 10,110,649	contains similarity to Saccharomyces cerevisiae RNA polymerase I subunit A34.5; SGD:YJL148W
14	F09C6.1	F09C6.1	n/a	chrV 16,887,916	contains similarity to Interpro domain IPR008999 (Actin-crosslinking proteins)
15	asic-2	T28F4.2	n/a	chrI 7,481,759	C. elegans ASIC-2 protein; contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domains IPR001873 (Na+ channel, amiloride-sensitive), IPR004726 (Degenerin)
16	C31H2.3	C31H2.3	n/a	chrX 5,152,942
17	C43F9.5	C43F9.5	n/a	chrIV 10,590,044	contains similarity to Interpro domain IPR006150 (Cysteine-rich repeat)
18	C26F1.6	C26F1.6	n/a	chrV 7,772,218	C26F1.6 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that C26F1.6 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
19	F36D4.4	F36D4.4	n/a	chrV 9,404,118	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000832 (GPCR, family 2, secretin-like), IPR000276 (GPCR, rhodopsin-like)
20	F07C3.2	F07C3.2	n/a	chrV 9,226,731
21	ZC155.2	ZC155.2	n/a	chrIII 5,219,635	contains similarity to Interpro domains IPR000164 (Histone H3), IPR009072 (Histone-fold)
22	C12D5.9	C12D5.9	n/a	chrV 7,689,147	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
23	F49E12.7	F49E12.7	n/a	chrII 8,395,633	contains similarity to Mycobacterium tuberculosis Hypothetical protein (HoxN/HupN/NixA family nickel transporter).; TR:O05804
24	B0524.3	B0524.3	n/a	chrIII 1,888,918
25	ins-39	F21E9.4	n/a	chrX 1,344,119	ins-39 encodes an insulin-like peptide.
26	T02E9.3	T02E9.3	n/a	chrV 11,364,314	T02E9.3 encodes a homolog of human melatonin type 1b receptors, and more generally of mammalian dopamine and serotonin (5-HT) receptors; T02E9.3 is partly required for male tail curling, with T02E9.3(RNAi) animals showing reduced curling in exogenous 5-HT; T02E9.3 is required for full sensitivity to 5-HT, normal brood sizes, and pharyngeal pumping; T02E9.3 is expressed in head and tail neurons.
27	F15G9.2	F15G9.2	n/a	chrX 9,713,365	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IAW6
28	ZC239.14	ZC239.14	n/a	chrII 3,221,697	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
29	C50D2.6	C50D2.6	n/a	chrII 86,096
30	str-41	R13D7.1	n/a	chrV 7,412,508	C. elegans STR-41 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
31	C55A1.7	C55A1.7	n/a	chrV 15,647,283	contains similarity to Escherichia coli TolA protein.; SW:TOLA_ECOLI
32	clec-146	Y48E1B.9	n/a	chrII 13,592,126	C. elegans CLEC-146 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
33	F18E9.4	F18E9.4	n/a	chrX 8,582,026
34	C03H5.7	C03H5.7	n/a	chrII 381,414	contains similarity to Interpro domains IPR001991 (Sodium:dicarboxylate symporter), IPR001958 (Tetracycline resistance protein, TetA)
35	CD4.5	CD4.5	n/a	chrV 5,590,729
36	srj-50	T03D3.2	n/a	chrV 2,833,942	C. elegans SRJ-50 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
37	K04F1.11	K04F1.11	n/a	chrV 1,660,979	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
38	R05A10.3	R05A10.3	n/a	chrIV 14,175,025	contains similarity to Saccharomyces cerevisiae <b><u>C</u></b>onserved <b><u>O</u></b>ligomeric <b><u>G</u></b>olgi complex <b><u>1</u></b><br> Complexed with Cog8p; interacts with Cog2p; SGD:YGL223C
39	F20D1.3	F20D1.3	n/a	chrX 14,977,334	contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR000018 (P2Y4 purinoceptor), IPR015915 (Kelch-type beta propeller)
40	acc-4	T27E9.9	5e-33	chrIII 13,482,337	C. elegans ACC-4 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
41	C18H7.6	C18H7.6	n/a	chrIV 590,772	contains similarity to Interpro domain IPR000817 (Prion protein)
42	srz-10	ZK1037.11	n/a	chrV 15,308,296	C. elegans SRZ-10 protein ;
43	moe-3	F32A11.6	n/a	chrII 13,163,070	moe-3 encodes a CCCH tandem zinc finger (TZF) protein; while loss of moe-3 activity via RNAi alone results in no obvious abnormalities, animals triply mutant for moe-3, oma-1, and oma-2 demonstrate oocyte maturation defects, indicating that these genes likely function redundantly during germline development; in situ hybridization experiments indicate that moe-3 mRNA expression is relatively weak and restricted to the distal region of the gonad; based upon its sequence similarity to other TZF proteins, such as MEX-5 and POS-1, the product of MOE-3 is predicted to function as an RNA-binding protein.
44	nca-2	C27F2.2	n/a	chrIII 4,972,657	nca-2 encodes a novel, four-domain alpha1U Ca2+ channel subunit; nca-2 functions redundantly with a paralog, nca-1, to regulate locomotion and the response to specific volatile anesthetics; in regulating these processes, nca-1 and nca-2 function in the same pathway as unc-79, which encodes a conserved novel protein that positively regulates levels of NCA-1 and NCA-2 protein; nca-2::gfp reporters are expressed in the nervous system in a few pharyngeal neurons, many nerve ring interneurons, most ventral nerve motor cord neurons, and in neurons and muscles in the tail; diffuse expression is also seen in vulval muscles and the intestine.
45	lev-1	F09E8.7	0.00003	chrIV 13,176,746	lev-1 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR) which, when mutated, confers resistance to levamisole; LEV-1 is required for completely normal locomotion, and forms a cation channel when coexpressed with UNC-38 or UNC-63 and UNC-29; LEV-1 falls into the 'UNC-29' class of nAChR subunits, which includes UNC-29, ACR-2, and ACR-3.
46	sro-1	D1022.6	n/a	chrII 7,461,799	C. elegans SRO-1 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
47	F53F4.2	F53F4.2	n/a	chrV 13,589,230	contains similarity to Hordeum vulgare Glycine-rich cell wall structural protein precursor.; SW:P17816
48	set-11	F34D6.4	n/a	chrII 2,692,391	set-11 encodes a putative histone H3 lysine-9 methyltransferase orthologous to human EHMT1 (OMIM:607001, mutated in 9q subtelomeric deletion syndrome) and EHMT2 (OMIM:604599); neither set-11(n4488) nor set-11(RNAi) have any obvious phenotypes.
49	lgc-37	ZC482.5	9.999999999999999e-51	chrIII 12,789,021	ZC482.5 is orthologous to the human gene GAMMA-AMINOBUTYRIC ACID A RECEPTOR GAMMA 2 (GABRG2; OMIM:137164), which when mutated leads to disease.
50	Y7A5A.3	Y7A5A.3	n/a	chrX 15,783,069