UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZC404.11	ZC404.11	2e-153	chrV 6,803,107	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
2	clec-255	F11D11.1	n/a	chrV 18,770,210	C. elegans CLEC-255 protein; contains similarity to Interpro domains IPR013278 (Apoptosis regulator, Bcl-2), IPR000694 (Proline-rich region), IPR000480 (Glutelin), IPR003882 (Pistil-specific extensin-like protein)
3	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
4	K02E7.3	K02E7.3	n/a	chrII 1,077,813	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
5	pqn-45	F56F3.1	n/a	chrIII 4,473,243	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
6	cdk-5	T27E9.3	n/a	chrIII 13,465,418	cdk-5 encodes a putative homolog of cyclin dependent kinase 5 that affects pronuclear migration and rotation in one-cell embryos and may affect neuronal development; expressed in neurons.
7	mes-2	R06A4.7	n/a	chrII 14,386,115	mes-2 encodes a SET domain-containing protein that is orthologous to the Drosophila Polycomb group protein Enhancer of zeste [E(Z)]; as a member of a Polycomb-like chromatin repressive complex with MES-3 and MES-6, MES-2 is required maternally for normal germline development and during larval development, for anteroposterior patterning; during germline development, the MES-2/MES-3/MES-6 complex is believed to be essential for maintaining repression of the X chromosome, and in transgenic animals, the complex is necessary for germline repression of repetitive transgenes; in axial patterning, the MES-2/MES-3/MES-6 complex is required in somatic tissues for maintaining homeotic gene repression, acting upstream of the Hox genes lin-39, mab-5, and egl-5, as well as the egl-5 target gene lin-32; in addition, MES-2 activity is required for normal levels and localization of MES-3 in >24-cell-stage embryos; MES-2 expression is detected in the primordial germ cells and germline nuclei throughout development, in all nuclei in early embryos, and in somatic nuclei, including those of the male tail, in L2 and L3 larvae; in the nucleus, MES-2 appears to localize to chromatin.
8	D1044.6	D1044.6	n/a	chrIII 5,539,373	contains similarity to Drosophila melanogaster Flybase gene name is CG2839-PA;; FLYBASE:CG2839
9	str-170	T08B6.7	n/a	chrIV 4,878,848	C. elegans STR-170 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
10	F35A5.5	F35A5.5	n/a	chrX 3,794,638	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR000976 (Wilm's tumour protein)
11	ani-2	K10B2.5	n/a	chrII 6,363,196	ani-2 encodes one of three C. elegans anillins; ANI-2 activity is required in the syncytial gonad for proper gonad structure and oocyte formation; specifically, ANI-2 appears to be required for maintaining the structure of the rachis, the syncytial compartment of germline cytoplasm that connects developing ooctyes; in the adult gonad, ANI-2 localizes to the surface of the rachis.
12	M01G12.6	M01G12.6	n/a	chrI 12,120,129	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
13	T23C6.3	T23C6.3	n/a	chrX 17,137,111
14	F41E6.7	F41E6.7	n/a	chrV 8,598,409
15	ZK945.4	ZK945.4	n/a	chrII 10,104,330	contains similarity to Pfam domains PF00621 (RhoGEF domain) , PF00169 (PH domain) contains similarity to Interpro domains IPR000219 (Dbl homology (DH) domain), IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type), IPR015721 (Rho GTP exchange factor)
16	VF39H2L.1	VF39H2L.1	n/a	chrI 8,645,323	contains similarity to Pfam domain PF05739 SNARE domain contains similarity to Interpro domains IPR010989 (t-SNARE), IPR000727 (Target SNARE coiled-coil region)
17	F28C10.1	F28C10.1	n/a	chrX 543,683
18	srh-244	C03G6.9	n/a	chrV 7,344,629	C. elegans SRH-244 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	clec-190	M199.4	n/a	chrIV 15,125,488	C. elegans CLEC-190 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
20	ZC168.3	ZC168.3	n/a	chrIV 10,733,704	contains similarity to Homo sapiens Origin recognition complex subunit 5; ENSEMBL:ENSP00000297431
21	str-81	T26H2.6	n/a	chrV 19,226,172	C. elegans STR-81 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	Y102A5C.2	Y102A5C.2	n/a	chrV 16,919,147	contains similarity to Saccharomyces cerevisiae anti-silencing protein that causes depression of silent loci when overexpressed; SGD:YJL115W
23	rfc-1	C54G10.2	n/a	chrV 14,644,310	C. elegans RFC-1 protein; contains similarity to Pfam domains PF00004 (ATPase family associated with various cellular activities (AAA)) , PF08519 (Replication factor RFC1 C terminal domain) contains similarity to Interpro domains IPR013725 (DNA replication factor RFC1, C-terminal), IPR003959 (AAA ATPase, core), IPR008921 (DNA polymerase III clamp loader subunit, C-terminal), IPR012178 (DNA replication factor C, large subunit), IPR003593 (AAA+ ATPase, core), IPR001984 (Peptidase S16, Lon protease)
24	C53C7.3	C53C7.3	n/a	chrX 13,049,643	contains similarity to Triticum aestivum Alpha/beta-gliadin A-V precursor (Prolamin).; SW:GDA5_WHEAT
25	C50C3.1	C50C3.1	n/a	chrIII 8,192,662	contains similarity to Pfam domain PF00642 Zinc finger C-x8-C-x5-C-x3-H type (and similar) contains similarity to Interpro domain IPR000571 (Zinc finger, CCCH-type)
26	gei-6	C05C8.4	n/a	chrV 7,228,595	C. elegans GEI-6 protein; contains similarity to Interpro domain IPR000694 (Proline-rich region)
27	ZC196.4	ZC196.4	n/a	chrV 8,734,518	contains similarity to Pfam domain PF05218 Protein of unknown function (DUF713) contains similarity to Interpro domains IPR007883 (Protein of unknown function DUF713), IPR000565 (DNA topoisomerase, type IIA, subunit B)
28	ZK593.8	ZK593.8	n/a	chrIV 10,938,663	contains similarity to Pfam domains PF07719 (Tetratricopeptide repeat) , PF02661 (Fic protein family) contains similarity to Interpro domains IPR003812 (Filamentation induced by cAMP protein Fic), IPR011990 (Tetratricopeptide-like helical), IPR013105 (Tetratricopeptide TPR2), IPR013026 (Tetratricopeptide region)
29	C45G9.2	C45G9.2	n/a	chrIII 5,069,704	contains similarity to Pfam domain PF01207 Dihydrouridine synthase (Dus) contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR003733 (Thiamine monophosphate synthase), IPR001269 (Dihydrouridine synthase, DuS)
30	M18.6	M18.6	n/a	chrIV 12,122,042	contains similarity to Interpro domain IPR003111 (Peptidase S16, lon N-terminal)
31	K04B12.3	K04B12.3	n/a	chrII 14,444,229	contains similarity to Anopheles gambiae str PEST AGAP010179-PA (Fragment).; TR:Q7Q0T1
32	taf-6.1	W09B6.2	n/a	chrII 1,130,167	C. elegans TAF-6.1 protein; contains similarity to Pfam domains PF07571 (Protein of unknown function (DUF1546)) , PF02969 (TATA box binding protein associated factor (TAF)) contains similarity to Interpro domains IPR009072 (Histone-fold), IPR004823 (TATA box binding protein associated factor (TAF)), IPR011442 (Protein of unknown function DUF1546)
33	C28A5.2	C28A5.2	n/a	chrIII 4,437,117	contains similarity to Interpro domain IPR001564 (Nucleoside diphosphate kinase)
34	F49C5.5	F49C5.5	n/a	chrII 12,546,186
35	M151.2	M151.2	n/a	chrII 3,632,782	contains similarity to Interpro domain IPR000533 (Tropomyosin)
36	C41D11.1	C41D11.1	n/a	chrI 4,458,028
37	F26E4.5	F26E4.5	n/a	chrI 9,769,984	F26E4.5 encodes an SH2 domain-containing tyrosine kinase related to the vertebrate FER non-receptor protein tyrosine kinase; loss of F26E4.5 activity in an RNAi-hypersensitive strain results in axon guidance defects indicating that F26E4.5 likely plays a role in regulation of axon navigation.
38	fbxa-192	F57G4.8	n/a	chrV 17,645,592	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
39	C32B5.6	C32B5.6	n/a	chrII 969,468
40	sre-9	C17E7.3	n/a	chrV 3,896,569	C. elegans SRE-9 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
41	T21H3.5	T21H3.5	n/a	chrV 1,159,760
42	B0564.7	B0564.7	n/a	chrIV 13,102,647	contains similarity to Aedes aegypti Cell cycle progression.; TR:Q16U20
43	osm-11	F11C7.5	n/a	chrX 17,420,817	C. elegans OSM-11 protein ;
44	acl-2	T06E8.1	n/a	chrV 10,029,692	T06E8.1 is orthologous to the human gene 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 2 (LYSOPHOSPHATIDIC ACID ACYLTRANSFERASE, BETA) (AGPAT2; OMIM:603100), which when mutated leads to disease; T06E8.1 protein is predicted to be mitochondrial.
45	mys-1	VC5.4	n/a	chrV 7,083,085	mys-1 encodes a MYST family histone acetyltransferase orthologous to Drosophila EG0007.7, human TIP60, and S. cerevisiae Esa1p; during vulval development, mys-1 acts as Class C synMuv gene: mys-1 mutations enhance mutations in components of the C. elegans NuRD and Rb repressor complexes that negatively regulate expression of genes required for vulval induction; in addition, mys-1(RNAi) enhances mutations in pha-4, which encodes a FoxA transcription factor required for pharyngeal organogenesis; mys-1 mutations also cause a synthetic slow growth phenotype in combination with mutations in the MCD-1 zinc-finger protein; thus, mys-1 activity is essential for proper cell fate specification of different cell types at different times during C. elegans development.
46	mvb-12	C06A6.3	n/a	chrIV 7,831,453	C. elegans MVB-12 protein ; contains similarity to Homo sapiens Isoform 1 of Protein FAM125B; ENSEMBL:ENSP00000354772
47	K02B2.6	K02B2.6	n/a	chrIV 5,961,963
48	F43H9.3	F43H9.3	n/a	chrV 8,024,072	contains similarity to Homo sapiens PAP associated domain containing 4; ENSEMBL:ENSP00000296783
49	cdc-25.1	K06A5.7	n/a	chrI 6,470,859	cdc-25.1 encodes a CDC25 phosphatase homolog that affects embryonic viability, meiosis, mitosis, proliferation of the intestine (E cell lineage), and germ line proliferation; it is expressed in the developing germline, in the nuclei of oocytes, embryonic nuclei, nuclei of embryonic cortical membranes, and sperm pronuclei, and in the germline precursors Z2 and Z3.
50	C40H5.2	C40H5.2	n/a	chrX 11,754,976	contains similarity to Bifidobacterium longum Possible magnesium and cobalt transport protein.; TR:Q8G4E0