UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ins-24	ZC334.3	1e-48	chrI 14,031,394	ins-24 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-24 is one of 38 insulin-like peptides in C. elegans, but as loss of INS-24 function via RNA-mediated interference does not result in any abnormalities, the precise role of INS-24 in C. elegans development is not yet clear.
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	wht-6	T26A5.1	n/a	chrIII 6,473,428	C. elegans WHT-6 protein; contains similarity to Pfam domains PF01061 (ABC-2 type transporter) , PF00005 (ABC transporter) contains similarity to Interpro domains IPR003439 (ABC transporter-like), IPR003593 (AAA+ ATPase, core), IPR013525 (ABC-2 type transporter)
4	C16D6.2	C16D6.2	n/a	chrX 12,544,267	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR001402 (Prolactin-releasing peptide receptor), IPR017452 (GPCR, rhodopsin-like superfamily), IPR000405 (Galanin receptor), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
5	C01B12.5	C01B12.5	n/a	chrII 10,817	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domains IPR000615 (Bestrophin), IPR000802 (Arsenical pump membrane protein)
6	far-5	F15B9.3	n/a	chrV 12,996,198	far-5 encodes a member of a class of fatty acid-and retinol-binding proteins that are known to be secreted by parasitic nematodes and plants; far-5 binds lipid in fluorescence-based assays, however, the precise function of far-5 is not known.
7	C56E6.6	C56E6.6	n/a	chrII 6,542,233	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
8	clec-183	T20D3.1	n/a	chrIV 9,328,354	C. elegans CLEC-183 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
9	K03E5.1	K03E5.1	n/a	chrI 3,431,349	contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domains IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR000859 (CUB)
10	C05C10.1	C05C10.1	n/a	chrII 9,918,735	contains similarity to Pfam domain PF00328 Histidine acid phosphatase contains similarity to Interpro domain IPR000560 (Histidine acid phosphatase)
11	C06C6.6	C06C6.6	n/a	chrV 15,990,153	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
12	str-4	C50B6.10	n/a	chrV 13,338,836	C. elegans STR-4 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
13	tsp-8	F33C8.3	n/a	chrX 14,727,975	tsp-8 is orthologous to the human gene KANGAI 1 (SUPPRESSION OF TUMORIGENICITY 6, PROSTATE; CD82 ANTIGEN (R2 LEUKOCYTE ANTIGEN, ANTIGEN DETECTED BY MONOCLONAL AND ANTIBODY IA4)) (KAI1; OMIM:600623), which when mutated leads to disease.
14	ZK384.3	ZK384.3	n/a	chrV 18,730,891	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001412 (Aminoacyl-tRNA synthetase, class I, conserved site), IPR001461 (Peptidase A1)
15	C14A6.5	C14A6.5	n/a	chrV 18,164,125	contains similarity to Arabidopsis thaliana Calreticulin 2 precursor.; SW:CRT2_ARATH
16	srd-30	F07C4.5	n/a	chrV 7,630,532	C. elegans SRD-30 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
17	H35B03.1	H35B03.1	n/a	chrIV 5,727,641
18	srh-296	Y94A7B.4	n/a	chrV 17,811,540	C. elegans SRH-296 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	sre-14	C42C1.1	n/a	chrIV 12,260,640	C. elegans SRE-14 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR000326 (Phosphatidic acid phosphatase type 2/haloperoxidase), IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
20	F28C6.5	F28C6.5	n/a	chrII 8,599,990	contains similarity to Mus musculus Activity-dependent neuroprotector (Activity-dependent neuroprotectivesprotein).; SW:ADNP_MOUSE
21	W06G6.10	W06G6.10	n/a	chrV 16,646,964	contains similarity to Escherichia coli O157:H7 C4-type zinc finger protein (TraR family).; TR:Q8X2P7
22	K11H12.4	K11H12.4	n/a	chrIV 674,988	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
23	hyl-2	K02G10.6	n/a	chrX 4,698,095	hyl-2 encodes a predicted transmembrane protein that is related to Saccharomyces cerevisiae LAG1 (longevity assurance gene), a protein preferentially expressed in young yeasts; by homology, HYL-2 is predicted to have several possible functions, including regulation of lipid, particularly ceramide, biosynthesis, regulation of lipid transport, and regulation of protein translocation in the endoplasmic reticulum ; however, as loss of hyl-2 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of hyl-2 in C. elegans development and/or behavior is not yet known.
24	F22G12.5	F22G12.5	n/a	chrI 13,172,567	contains similarity to Interpro domain IPR001765 (Carbonic anhydrase)
25	E01G4.1	E01G4.1	n/a	chrII 13,445,298	contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
26	F27C1.11	F27C1.11	n/a	chrI 5,439,915	contains similarity to Pfam domains PF00612 (IQ calmodulin-binding motif) , PF03607 (Doublecortin) , PF01477 (PLAT/LH2 domain) contains similarity to Interpro domains IPR001024 (Lipoxygenase, LH2), IPR008976 (Lipase/lipooxygenase, PLAT/LH2), IPR003533 (Doublecortin), IPR000048 (IQ calmodulin-binding region)
27	str-264	C06B8.4	n/a	chrV 15,491,810	C. elegans STR-264 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
28	srz-70	C09G12.6	n/a	chrIV 3,478,198	C. elegans SRZ-70 protein ;
29	cyp-34A8	B0213.14	n/a	chrV 3,966,310	C. elegans CYP-34A8 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR002397 (Cytochrome P450, B-class), IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
30	C33E10.5	C33E10.5	n/a	chrX 17,276,148	contains similarity to Interpro domain IPR000173 (Glyceraldehyde 3-phosphate dehydrogenase)
31	T20D3.11	T20D3.11	n/a	chrIV 9,349,648	contains similarity to Anopheles gambiae str PEST AGAP009276-PA (Fragment).; TR:Q7PVH5
32	C50A2.4	C50A2.4	n/a	chrIV 1,160,591	contains similarity to Pfam domain PF00178 Ets-domain contains similarity to Interpro domains IPR000418 (Ets), IPR011991 (Winged helix repressor DNA-binding)
33	grl-13	F32D1.4	n/a	chrV 4,363,652	grl-13 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-13 is expressed in larval arcade cells; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
34	F28G4.5	F28G4.5	n/a	chrV 16,290,444	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
35	F13H8.9	F13H8.9	n/a	chrII 6,280,371	contains similarity to Pfam domain PF00266 Aminotransferase class-V contains similarity to Interpro domains IPR016454 (Cysteine desulphurase, NifS), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR000192 (Aminotransferase, class V/Cysteine desulphurase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
36	T10B9.9	T10B9.9	n/a	chrII 9,775,421	contains similarity to Avian adenovirus gal1 Orf2 protein.; TR:Q64786
37	C36B7.3	C36B7.3	n/a	chrX 7,101,897
38	C33G8.2	C33G8.2	n/a	chrV 7,011,095	contains similarity to Interpro domains IPR002038 (Osteopontin), IPR005448 (Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)
39	C32H11.1	C32H11.1	n/a	chrIV 12,913,842	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003366 (CUB-like region)
40	C32H11.4	C32H11.4	n/a	chrIV 12,922,267	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
41	gcy-35	T04D3.4	n/a	chrI 13,329,337	C. elegans GCY-35 protein; contains similarity to Pfam domains PF07700 (Heme NO binding) , PF07701 (Heme NO binding associated) , PF00211 (Adenylate and Guanylate cyclase catalytic domain) contains similarity to Interpro domains IPR011644 (Haem NO binding), IPR011645 (Haem NO binding associated), IPR001054 (Adenylyl cyclase class-3/4/guanylyl cyclase)
42	Y39E4B.6	Y39E4B.6	n/a	chrIII 13,072,610	contains similarity to Rattus norvegicus Nucleolar protein NOP5 (Nucleolar protein 5) (Nopp140 associatedsprotein).; SW:NOP5_RAT
43	gcy-18	ZK896.8	n/a	chrIV 12,863,005	gcy-18 encodes a receptor-type guanylyl cyclase that, along with gcy-8 and gcy-23, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-18 functions redundantly with gcy-8 and gcy-23, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; in addition, microarray experiments indicate that gcy-18 expression is induced in daf-16(RNAi); daf-2(RNAi) double mutants and repressed in daf-2(RNAi) mutants, suggesting that GCY-18 activity may contribute to a shortened lifespan; consistent with this, loss of gcy-18 activity via RNAi does result in lifespan extension; GCY-18 is expressed exclusively in the AFD thermosensory neurons, where it localizes to sensory endings.
44	C03C10.4	C03C10.4	n/a	chrIII 4,097,487	contains similarity to Pfam domain PF05276 SH3 domain-binding protein 5 (SH3BP5) contains similarity to Interpro domain IPR007940 (SH3-binding 5)
45	sre-38	F15A4.1	n/a	chrII 12,458,457	C. elegans SRE-38 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
46	C10A4.1	C10A4.1	n/a	chrX 7,417,182	contains similarity to Pfam domain PF05699 hAT family dimerisation domain contains similarity to Interpro domain IPR008906 (HAT dimerisation)
47	D1065.3	D1065.3	n/a	chrV 4,060,947	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
48	F23B2.7	F23B2.7	n/a	chrIV 9,151,248	contains similarity to Homo sapiens similar to Cylicin I (Multiple-band polypeptide I); ENSEMBL:ENSP00000331556
49	Y81G3A.4	Y81G3A.4	n/a	chrII 13,092,774	contains similarity to Guillardia theta 60S acidic ribosomal protein P0.; TR:Q98S65
50	F11A5.4	F11A5.4	n/a	chrV 16,195,957	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR001019 (Guanine nucleotide binding protein (G-protein), alpha subunit), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras)