UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ins-26	ZC334.1	4e-53	chrI 14,037,463	ins-26 encodes an insulin-like peptide.
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	D1005.3	D1005.3	n/a	chrX 1,453,357	contains similarity to Pfam domain PF07716 Basic region leucine zipper contains similarity to Interpro domains IPR011700 (Basic leucine zipper), IPR004827 (Basic-leucine zipper (bZIP) transcription factor)
4	C31B8.7	C31B8.7	n/a	chrV 2,901,878	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
5	T28D9.7	T28D9.7	n/a	chrII 6,478,174	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
6	T28C12.2	T28C12.2	n/a	chrV 6,330,074	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
7	ugt-38	F10D2.7	n/a	chrV 7,146,544	C. elegans UGT-38 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR003567 (Cytochrome c-type biogenesis protein), IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
8	W03D8.8	W03D8.8	n/a	chrI 2,793,293	contains similarity to Pfam domains PF08840 (BAAT / Acyl-CoA thioester hydrolase C terminal) , PF04775 (Acyl-CoA thioester hydrolase / Bile acid-CoA amino acid N-acetyltransferase) contains similarity to Interpro domains IPR006862 (Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase), IPR014940 (BAAT/Acyl-CoA thioester hydrolase C-terminal), IPR016662 (Acyl-CoA thioesterase, long chain)
9	F53A9.9	F53A9.9	n/a	chrX 8,720,477	contains similarity to Bacillus subtilis Uncharacterized protein yeeK.; SW:O31510
10	nas-25	F46C5.3	n/a	chrII 8,827,065	nas-25 encodes an astacin-like metalloprotease; large-scale expression studies reveal that a nas-25::GFP promoter fusion is expressed in the pharynx and pharyngeal-intestinal valve.
11	F37H8.3	F37H8.3	n/a	chrII 11,182,323	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR011945 (Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal), IPR006402 (HAD-superfamily hydrolase, subfamily IA, variant 3), IPR005834 (Haloacid dehalogenase-like hydrolase)
12	K08D9.4	K08D9.4	n/a	chrV 3,199,601	contains similarity to Pfam domain PF06342 Alpha/beta hydrolase of unknown function (DUF1057) contains similarity to Interpro domains IPR008262 (Lipase, active site), IPR010463 (Protein of unknown function DUF1057, lipase putative), IPR003089 (Alpha/beta hydrolase)
13	C31A11.5	C31A11.5	n/a	chrV 16,304,427	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
14	unc-41	C27H6.1	n/a	chrV 9,971,233	unc-41 encodes an ortholog of Drosophila STONED A (STNA) required for normal locomotion; a beta-strand in the mu-adaptin-like domain of UNC-41 binds the C2A domain of SNT-1, and this binding is required for SNT-1 endocytosis, punctate localization of UNC-41 in neurons, and transgenic rescue of unc-41(e268) animals; UNC-41 is also required for normal secretion of EGL-17 from P6.p cells, and for embryonic viability; UNC-41 is expressed in the larval and adult nervous system; UNC-41, like other stonins, is an adaptin, and by orthology with stonins is predicted to be a protein adaptor that helps sort SNT-1 endocytotically.
15	srbc-34	Y113G7B.9	n/a	chrV 20,202,676	C. elegans SRBC-34 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
16	C28H8.7	C28H8.7	n/a	chrIII 5,886,352	contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
17	ptr-5	C53C11.3	n/a	chrX 17,322,508	ptr-5 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-5 is weakly required for normal molting from L4 to adult stages; PTR-5 is also required for normal growth to full size and locomotion; PTR-5 is expressed in head and tail neurons, and in ventral nerve cord.
18	nhr-63	C06C6.4	n/a	chrV 16,003,610	C. elegans NHR-63 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
19	C01G10.5	C01G10.5	n/a	chrV 15,089,276	contains similarity to Homo sapiens Glycine/tyrosine-rich protein; ENSEMBL:ENSP00000335001
20	R13A5.9	R13A5.9	n/a	chrIII 7,577,267	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR001958 (Tetracycline resistance protein, TetA), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
21	F40F9.8	F40F9.8	n/a	chrV 9,734,765	contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
22	F08D12.2	F08D12.2	n/a	chrII 2,782,368	contains similarity to Pfam domain PF04942 CC domain contains similarity to Interpro domain IPR007026 (Domian of unknown function, DUF-CC)
23	srz-60	C04C3.1	n/a	chrIV 3,429,627	C. elegans SRZ-60 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
24	F08D12.1	F08D12.1	n/a	chrII 2,790,710	contains similarity to Pfam domains PF08492 (SRP72 RNA-binding domain) , PF00515 (Tetratricopeptide repeat) (2), PF07720 (Tetratricopeptide repeat) contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR001440 (Tetratricopeptide TPR-1), IPR013699 (Signal recognition particle, SRP72 subunit, RNA-binding), IPR013026 (Tetratricopeptide region)
25	DC2.5	DC2.5	n/a	chrV 211,433	contains similarity to Pfam domain PF00439 Bromodomain contains similarity to Interpro domain IPR001487 (Bromodomain)
26	scl-10	F49E11.5	n/a	chrIV 13,049,134	C. elegans SCL-10 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
27	cyp-33C8	R08F11.3	n/a	chrV 3,802,105	C. elegans CYP-33C8 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
28	R08C7.5	R08C7.5	n/a	chrIV 4,431,281	contains similarity to Pfam domain PF03941 Inner centromere protein, ARK binding region contains similarity to Interpro domains IPR005819 (Histone H5), IPR005635 (Inner centromere protein, ARK binding region)
29	F46B6.9	F46B6.9	n/a	chrV 9,797,511	contains similarity to Candida albicans Probable ferric reductase transmembrane component (EC 1.16.1.7)s(Ferric-chelate reductase).; SW:FREL_CANAL
30	gst-40	F56B3.10	n/a	chrIV 761,476	C. elegans GST-40 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
31	abts-1	F52B5.1	n/a	chrI 8,302,240	abts-1 encodes an anion transporter; when expressed in Xenopus oocytes, ABTS-1 exhibits robust chloride transport, as well as chloride/bicarbonate exchange activity; abts-1 promoter gfp fusions are expressed primarily in neurons and hypodermis, with weak fluorescence also seen in the pharynx and body wall muscle cells.
32	math-11	C16C4.16	n/a	chrII 1,874,693	C. elegans MATH-11 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
33	ctl-1	Y54G11A.6	n/a	chrII 14,304,828	ctl-1 encodes one of three C. elegans catalases; CTL-1 exhibits catalase activity in vitro, and thus likely functions in vivo as an antioxidant enzyme that protects cells from reactive oxygen species; ctl-1 activity contributes to the extended lifespan seen in daf-2 mutant animals; in addition, ctl-1 expression is negatively regulated by DAF-2-mediated insulin signaling; as CTL-1 does not possess a C-terminal peroxisomal targeting signal (PTS), it is predicted to be a cytosolic catalase.
34	T05H10.3	T05H10.3	n/a	chrII 8,049,736
35	nhr-248	ZK218.6	n/a	chrV 17,103,987	C. elegans NHR-248 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
36	C56G2.3	C56G2.3	n/a	chrIII 6,347,461	contains similarity to Pfam domain PF01746 tRNA (Guanine-1)-methyltransferase contains similarity to Interpro domains IPR016009 (tRNA (guanine-N1-)-methyltransferase), IPR007356 (tRNA (guanine-N1-)-methyltransferase, eukaryotic)
37	inx-13	Y8G1A.2	n/a	chrI 3,751,248	inx-13 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; INX-13 is essential for larval development and osmoregulation, and may be a component of the gap junctions that link the excretory and hypodermal cells; INX-13 is expressed embryonically in hypodermis and post-embryonically, in hypodermal seam cells, the excretory cell, and the developing vulva and spermatheca; in hypodermal cells, INX-13 localizes to the plasma membrane at points of contact between adjacent cells.
38	Y18D10A.8	Y18D10A.8	n/a	chrI 12,848,697	contains similarity to Pfam domain PF00013 KH domain contains similarity to Interpro domains IPR016021 (MIF4-like, type 1/2/3), IPR004087 (K Homology), IPR000694 (Proline-rich region), IPR004088 (K Homology, type 1), IPR016024 (Armadillo-type fold)
39	F21F8.6	F21F8.6	n/a	chrV 8,266,564
40	Y43E12A.2	Y43E12A.2	n/a	chrIV 10,983,505	contains similarity to Interpro domain IPR001878 (Zinc finger, CCHC-type)
41	gpa-2	F38E1.5	n/a	chrV 8,372,499	gpa-2 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases that is involved in dauer formation and chemotaxis to water-soluble odorants; it is expressed in the phasmid neurons PHA and PHB, three pharyngeal neurons, one interneuron, three pairs of head neurons, and the anal sphincter muscle.
42	clec-191	F38C2.6	n/a	chrIV 16,280,134	C. elegans CLEC-191 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
43	B0303.14	B0303.14	n/a	chrIII 8,714,993	contains similarity to Homo sapiens 33 kDa protein; VG:OTTHUMP00000025234
44	T22H9.4	T22H9.4	n/a	chrV 335,754	contains similarity to Pfam domain PF00751 DM DNA binding domain contains similarity to Interpro domain IPR001275 (DM DNA-binding)
45	F25F6.1	F25F6.1	n/a	chrX 4,445,262
46	C08G5.5	C08G5.5	n/a	chrII 756,602	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003882 (Pistil-specific extensin-like protein)
47	inx-12	ZK770.3	n/a	chrI 3,757,299	inx-12 (innexin=invertebrate connexin analogue) encodes a protein of the innexin family; innexins are gap junction proteins similar in function, though dissimilar in sequence to the vertebrate connexins; innexins are the only known gap junction proteins in invertebrates; inx-12 and inx-13 appear to be a tandom duplication; RNA interference of inx-12 results in an arrest at the L1 larval stage with fluid filled dead rods; this phenotype and sequence homology to Drosophila innexins suggest that INX-12 may be required to form gap junctions between the excretory canal and hypodermis, thus playing an essential role in osmoregulation; an INX-12::GFP fusion protein is expressed in the excretory canal.
48	clec-149	K02F3.5	n/a	chrIII 824,783	K02F3.5 encodes a protein with a C-terminal C-type lectin domain that inhibits CEP-1- and HUS-1-dependent germline apoptosis, as do BMK-1, RAD-50, and RAD-51.
49	ZK742.3	ZK742.3	n/a	chrV 7,809,120	contains similarity to Pfam domain PF00724 NADH:flavin oxidoreductase / NADH oxidase family contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001155 (NADH:flavin oxidoreductase/NADH oxidase, N-terminal)
50	gst-33	C02A12.1	n/a	chrV 3,468,009	C. elegans GST-33 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)