UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZC317.2	ZC317.2	1e-65	chrV 5,460,748
2	F52B11.5	F52B11.5	n/a	chrIV 14,102,592	contains similarity to Clostridium perfringens Hypothetical protein CPE2159.; TR:Q8XIG1
3	C27F2.1	C27F2.1	n/a	chrIII 4,989,295	contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
4	egl-36	R07A4.1	n/a	chrX 10,739,267	egl-36 encodes a Shaw-type voltage-gated potassium channel that regulates egg laying and defecation; expression of egl-36::gfp reporters is observed in several different cell types including muscle cells such as the uterine and vulval egg-laying muscles, sensory, motor and interneurons, and the distal tip cells of the gonad; when expressed in a heterologous system, EGL-36 exhibits channel activity.
5	srw-65	Y38H6C.2	n/a	chrV 20,497,408	C. elegans SRW-65 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
6	Y39A1A.17	Y39A1A.17	n/a	chrIII 10,688,996	contains similarity to Interpro domain IPR001611 (Leucine-rich repeat)
7	srh-295	ZK1037.8	n/a	chrV 15,331,670	C. elegans SRH-295 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
8	Y49E10.25	Y49E10.25	n/a	chrIII 12,490,261	contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domain IPR002921 (Lipase, class 3)
9	Y43F8B.13	Y43F8B.13	n/a	chrV 19,459,852	contains similarity to Puumala virus Nucleocapsid protein (Fragment).; TR:Q8B3A4
10	nhr-150	C06B8.1	n/a	chrV 15,480,433	C. elegans NHR-150 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
11	F22D6.8	F22D6.8	n/a	chrI 7,099,204
12	pgp-10	C54D1.1	n/a	chrX 7,162,476	pgp-10 encodes an ATP-binding protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; PGP-10 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of pgp-10 activity via RNAi results in no obvious defects, the exact role of pgp-10 in C. elegans development and/or behavior is not yet known; pgp-10 promoter-gfp fusion proteins are expressed in larvae and adults in the intestine and hypodermis.
13	K01A12.3	K01A12.3	n/a	chrX 8,622,819	contains similarity to Interpro domain IPR000276 (GPCR, rhodopsin-like)
14	kqt-3	Y54G9A.3	n/a	chrII 13,704,530	kqt-3 encodes one of three C. elegans KCNQ-like potassium channel subunits and, with respect to humans, is most similar to the KCNQ1 channel protein which when mutated leads to inherited long QT syndrome (OMIM:607542); although loss of KQT-3 activity via large-scale RNAi screens results in no obvious abnormalities, KQT-3 likely functions to regulate cellular excitability as expression of KQT-3 in Xenopus oocytes can produce K+ channel currents that functionally resemble vertebrate M-currents; activity of these KQT-3 channels can be suppressed by coexpression with the human M1 muscarinic receptor and treatment with diacylglycerol analogs, although KQT-3 is less sensitive to each of these treatments than KQT-1; a KQT-3::GFP fusion protein is expressed in the anterior- and posterior-most intestinal cells, the anterior and posterior mechanosensory neurons ALM and PLM, amphid and phasmid neurons, and in some additional head neurons.
15	sri-31	B0454.2	n/a	chrII 3,051,657	C. elegans SRI-31 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
16	cyp-33C2	C45H4.17	n/a	chrV 2,185,028	C. elegans CYP-33C2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
17	T03F7.6	T03F7.6	n/a	chrV 11,295,604	contains similarity to Interpro domain IPR001036 (Acriflavin resistance protein)
18	F55A4.4	F55A4.4	n/a	chrX 1,025,409	contains similarity to Pfam domain PF00035 Double-stranded RNA binding motif contains similarity to Interpro domains IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like)
19	srbc-58	R09E12.2	n/a	chrV 776,135	C. elegans SRBC-58 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
20	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
21	hda-4	C10E2.3	n/a	chrX 16,737,045	hda-4 encodes a class II histone deacetylase that contains a putative MEF-2 DNA binding domain, a nuclear localization signal domain, and a single catalytic domain and may affect locomotion, body morphology, and growth; interacts with MEF-2 in in vitro assays and is expressed in body-wall muscle, neurons, and hypodermal seam cells
22	sru-25	F31F4.14	n/a	chrV 673,072	C. elegans SRU-25 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
23	T07H6.4	T07H6.4	n/a	chrX 6,284,028	contains similarity to Pfam domain PF00084 Sushi domain (SCR repeat) contains similarity to Interpro domains IPR002396 (Selectin (CD62E/L/P antigen)), IPR000436 (Sushi/SCR/CCP), IPR016060 (Complement control module)
24	nhr-268	K06B4.6	n/a	chrV 15,690,903	C. elegans NHR-268 protein
25	K03B8.8	K03B8.8	n/a	chrV 11,410,221	contains similarity to Interpro domains IPR006030 (Molluscan rhodopsin C-terminal tail), IPR000694 (Proline-rich region)
26	glr-3	K10D3.1	n/a	chrI 7,119,675	glr-3 encodes a protein that contains a ligand-gated ion channel domain and a receptor family ligand binding domain with similarity to kainate-selective ionotropic glutamate receptor 2 (human GRIK2); expressed in the RIA neuron.
27	K02E10.5	K02E10.5	n/a	chrX 2,477,930
28	C24A8.1	C24A8.1	n/a	chrX 4,323,582	C24A8.1 encodes an homolog of mammalian D2 or D3 dopamine receptors, and a paralog of DOP-2/-3; C24A8.1 is expressed in the nervous system; because of its paralogy, C24A8.1 might act redundantly with DOP-2 to promote the basal slowing response to bacterial feeding, or it might account for the residual response to excess dopamine seen in triple dop-1/-2/-3 mutants; but C24A8.1 otherwise has no obvious function in RNAi assays of brood size, egg laying, pharyngeal pumping, locomotion, or male mating.
29	Y6B3B.1	Y6B3B.1	n/a	chrI 13,699,504	contains similarity to Interpro domain IPR000533 (Tropomyosin)
30	F55G1.1	F55G1.1	n/a	chrIV 7,492,779
31	F56C3.7	F56C3.7	n/a	chrX 1,370,660
32	srj-33	T07C12.1	n/a	chrV 9,936,513	C. elegans SRJ-33 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
33	F22E5.12	F22E5.12	n/a	chrII 2,646,586	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
34	F52C12.4	F52C12.4	n/a	chrIV 1,934,886	contains similarity to Pfam domains PF01535 (PPR repeat) , PF02141 (DENN (AEX-3) domain) , PF03456 (uDENN domain) , PF03455 (dDENN domain) contains similarity to Interpro domains IPR005112 (dDENN), IPR012336 (Thioredoxin-like fold), IPR005113 (uDENN), IPR002885 (Pentatricopeptide repeat), IPR001194 (DENN)
35	C06B3.7	C06B3.7	n/a	chrV 13,910,615	contains similarity to Streptococcus agalactiae Tn5252, relaxase.; TR:Q8DZ67
36	srw-4	F37B4.8	n/a	chrV 2,887,985	C. elegans SRW-4 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
37	F39F10.2	F39F10.2	n/a	chrX 16,895,317	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
38	glb-2	C06E4.7	n/a	chrIV 7,262,720	glb-2 encodes a globin; glb-2 transcription is higher in L3 and dauers than in young adults; glb-2 has no obvious function in mass RNAi assays.
39	Y51H1A.7	Y51H1A.7	n/a	chrII 13,897,024	contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR000783 (RNA polymerase, subunit H/Rpb5 C-terminal)
40	clec-34	T25E12.8	n/a	chrV 16,736,555	C. elegans CLEC-34 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
41	clec-195	Y116A8C.21	n/a	chrIV 17,044,558	C. elegans CLEC-195 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
42	F37H8.2	F37H8.2	n/a	chrII 11,173,534	contains similarity to Saccharomyces cerevisiae Structural maintenance of chromosomes (SMC) protein; SGD:YOL034W
43	str-122	W03D2.10	n/a	chrIV 4,067,151	C. elegans STR-122 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	M01F1.7	M01F1.7	n/a	chrIII 3,525,420	M01F1.7 encodes a phosphatidylinositol transfer protein, with a C-terminal DDHD domain, that is orthologous to RETINAL DEGENERATION B (RDGB) in D. melanogaster, as well as other orthologs in mammals (NIR1-3); M01F1.7 is expressed in the egg membrane, the germline, the spermatheca and three pairs of head neurons; while M01F1.7 would be expected to mediate PIP(2) signalling in either neuronal function or cytokinesis, it has not yet had a published mutant phenotype, and has no obvious function in mass RNAi assays.
45	R06B9.2	R06B9.2	n/a	chrII 13,767,269	contains similarity to Pfam domain PF00339 Arrestin (or S-antigen), N-terminal domain contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011021 (Arrestin-like, N-terminal)
46	srd-5	T19E7.5	n/a	chrIV 5,673,565	C. elegans SRD-5 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR004268 (Virulence factor MVIN-like)
47	sre-45	F54F11.3	n/a	chrII 13,520,326	C. elegans SRE-45 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
48	Y7A5A.2	Y7A5A.2	n/a	chrX 15,772,148	contains similarity to Aquifex aeolicus Hypothetical protein AQ_372.; SW:Y372_AQUAE
49	T07D3.5	T07D3.5	n/a	chrII 886,263	contains similarity to Pfam domain PF06828 Fukutin-related contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR009644 (Fukutin-related)
50	ptr-13	K07C10.1	n/a	chrII 11,159,735	ptr-13 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-13 is weakly required for normal molting from L4 to adult stages; PTR-13 is also required for normal growth to full size and locomotion.