UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZC247.1	ZC247.1	0	chrI 10,271,766	contains similarity to Drosophila melanogaster Flybase gene name is CG32377-PA;; FLYBASE:CG32377
2	F27E5.3	F27E5.3	n/a	chrII 10,142,746	contains similarity to Homo sapiens Isoform 1 of Cell division cycle 2-related protein kinase 7; ENSEMBL:ENSP00000300647
3	let-75	R06C7.10	n/a	chrI 7,263,197	let-75 encodes a pharynx-specific type II myosin heavy chain (MHC D); LET-75 is required for pharyngeal muscle contraction and thus for normal feeding behavior and post-embryonic development; in vitro, the LET-75 tail domain interacts with ITR-1, an IP3 receptor, and this interaction has been proposed to mediate, in vivo, increased pharnygeal pumping in response to food; LET-75 is expressed exclusively in pharyngeal muscle.
4	dod-21	C32H11.10	n/a	chrIV 12,937,319	C. elegans DOD-21 protein; contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
5	fbxa-90	Y102A5C.19	n/a	chrV 16,967,704	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
6	R05H10.1	R05H10.1	n/a	chrII 14,852,898	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
7	ugt-43	F01D4.1	n/a	chrIV 10,466,113	C. elegans UGT-43 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
8	pgp-3	ZK455.7	n/a	chrX 11,354,551	pgp-3 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; with PGP-1, PGP-3 is required for defense against the pathogenic Pseudomonas aeruginosa strain PA14, and may facilitate ATP-dependent efflux of the toxic phenazine compounds produced by the bacteria; PGP-3 is also required for resistance to colchicine and chloroquine; PGP-3 is expressed in the apical membranes of the excretory cell and the intestinal cells; loss of pgp-3 activity via large-scale RNAi screens does not result in any obvious abnormalities.
9	nspb-7	C01G12.2	n/a	chrII 14,578,358	C. elegans NSPB-7 protein ;
10	C25D7.5	C25D7.5	n/a	chrV 15,054,998	contains similarity to Pfam domain PF00753 (Metallo-beta-lactamase superfamily)
11	B0272.4	B0272.4	n/a	chrX 9,429,267	contains similarity to Pfam domain PF00378 Enoyl-CoA hydratase/isomerase family contains similarity to Interpro domain IPR001753 (Crotonase, core)
12	clec-68	F56D6.1	n/a	chrIV 3,927,681	C. elegans CLEC-68 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
13	Y39G8C.2	Y39G8C.2	n/a	chrII 14,096,329	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
14	ZK180.2	ZK180.2	n/a	chrIV 4,504,345	contains similarity to Pfam domain PF01094 Receptor family ligand binding region contains similarity to Interpro domains IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B), IPR001828 (Extracellular ligand-binding receptor), IPR000923 (Blue (type 1) copper domain)
15	K11C4.1	K11C4.1	n/a	chrV 6,897,709	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
16	C14A4.8	C14A4.8	n/a	chrII 10,597,545	contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
17	cpb-2	C30B5.3	n/a	chrII 6,193,942	cpb-2 encodes a cytoplasmic polyadenylation element binding (CPEB) protein homolog, expressed specifically in the spermatogenic germ line; CPB-2 is dispensable for oogenesis, in contrast to CPEBs in vertebrates (Xenopus), arthropods (Drosophila), and molluscs (Spisula), which all participate in oogenesis.
18	B0207.7	B0207.7	n/a	chrI 5,946,551	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
19	T06D4.4	T06D4.4	n/a	chrII 3,393,492	T06D4.4 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; T06D4.4 has no clear orthologs in other organisms.
20	F14F7.4	F14F7.4	n/a	chrIII 13,028,908	contains similarity to Interpro domain IPR003944 (Protease-activated receptor 4)
21	Y48A6B.8	Y48A6B.8	n/a	chrIII 11,028,225	contains similarity to Interpro domains IPR003547 (Serine/threonine protein kinase, yersinia), IPR013022 (Xylose isomerase-like, TIM barrel)
22	spe-15	F47G6.4	n/a	chrI 1,456,004	spe-15 encodes an unconventional myosin, and is homologous to both Drosophila and mouse myosin VI; spe-15 was identified in screens for mutants that have defective spermatogenesis; spe-15 is required during the terminal stages of spermatogenesis for the asymmetric partitioning of organelles like the mitochondria and for the proper partitioning of specialized structures called the fibrous-body membranous organelles into the spermatid; mutant spe-15 spermatids contain actin filaments in contrast to wild-type which lack them; spe-15 is also required for the proper morphology and activation of the spermatid; the human gene MYOSIN VI (MYO6; OMIM:600970), when mutated leads to disease that affects hearing.
23	C16D9.5	C16D9.5	n/a	chrV 8,244,484	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
24	tba-7	T28D6.2	n/a	chrIII 11,369,983	C. elegans TBA-7 protein; contains similarity to Pfam domains PF00091 (Tubulin/FtsZ family, GTPase domain) , PF03953 (Tubulin/FtsZ family, C-terminal domain) contains similarity to Interpro domains IPR002454 (Gamma tubulin), IPR002452 (Alpha tubulin), IPR002453 (Beta tubulin), IPR000217 (Tubulin), IPR003008 (Tubulin/FtsZ, GTPase), IPR004057 (Epsilon tubulin), IPR002967 (Delta tubulin), IPR000158 (Cell division protein FtsZ, N-terminal), IPR008280 (Tubulin/FtsZ, C-terminal)
25	C50F4.2	C50F4.2	n/a	chrV 9,533,151	C50F4.2 encodes a putative 6-phosphofructokinase, paralogous to Y71H10A.1; C50F4.2 is required for fertility, full body size, and normally rapid growth in mass RNAi assays; C50F4.2 transcripts are enriched during spermatogenesis.
26	Y53C10A.10	Y53C10A.10	n/a	chrI 12,024,518	contains similarity to Interpro domain IPR000694 (Proline-rich region)
27	bath-37	K08E4.5	n/a	chrIV 12,073,207	C. elegans BATH-37 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
28	F35E8.1	F35E8.1	n/a	chrV 15,904,615	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
29	F42G8.8	F42G8.8	n/a	chrIV 8,120,646	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
30	C09G1.4	C09G1.4	n/a	chrX 15,992,503	contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
31	R09H10.2	R09H10.2	n/a	chrIV 10,606,027	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
32	ZK795.2	ZK795.2	n/a	chrIV 12,557,986	contains similarity to Homo sapiens hypothetical protein; ENSEMBL:ENSP00000352916
33	C25E10.5	C25E10.5	n/a	chrV 9,031,538	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
34	abt-2	F12B6.1	n/a	chrI 2,264,395	abt-2 encodes a predicted ATP-binding cassette (ABC) transporter that is a member of the ABCA subfamily of transport proteins; ABT-2 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of abt-2 activity via RNAi results in no obvious defects, the precise role of abt-2 in C. elegans development and/or behavior is not yet known.
35	arf-1.1	F45E4.1	n/a	chrIV 7,635,253	arf-1.1 encodes a member of the ADP-ribosylation factor family.
36	Y54G9A.4	Y54G9A.4	n/a	chrII 13,714,353	contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)
37	grl-4	F42C5.7	n/a	chrIV 7,310,282	grl-4 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-4 is expressed in pharynx, reproductive system, vulva, larval neurons, and larval rectal epithelium; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
38	B0218.5	B0218.5	n/a	chrIV 8,155,831	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
39	M117.4	M117.4	n/a	chrIV 11,832,142	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003882 (Pistil-specific extensin-like protein)
40	C32H11.9	C32H11.9	n/a	chrIV 12,935,630	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
41	lgc-25	R03E1.3	n/a	chrX 14,160,175	C. elegans LGC-25 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR003567 (Cytochrome c-type biogenesis protein), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
42	M02F4.3	M02F4.3	n/a	chrX 3,038,574	M02F4.3 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C01H6.6, C33D12.2, C52D10.12, R04E5.2, and R13G10.4; by orthology with MAM3, M02F4.3 may participate in metal homoeostasis; M02F4.3, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; M02F4.3 has no obvious function in RNAi assays.
43	F16G10.5	F16G10.5	n/a	chrII 2,368,093
44	K01A6.4	K01A6.4	n/a	chrIV 11,739,659	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR001419 (HMW glutenin)
45	W03A5.2	W03A5.2	n/a	chrIII 5,407,000	W03A5.2 is orthologous to the human gene UNKNOWN (PROTEIN FOR MGC:19580) (GGCX; OMIM:137167), which when mutated leads to disease.
46	ZK892.5	ZK892.5	n/a	chrII 10,008,728	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
47	gcy-12	F08B1.2	n/a	chrII 5,314,665	gcy-12 encodes a membrane guanylyl cyclase; a gcy-12::GFP reporter is expressed in the PHA neurons as well as in a number of head sensory neurons including AFD, AWC, and ASE; when expressed in COS-M6 cells, GCY-12 exhibits temperature-dependent guanylyl cyclase activity.
48	Y38H6C.15	Y38H6C.15	n/a	chrV 20,530,900	contains similarity to Interpro domain IPR006017 (Caldesmon)
49	Y57G11C.6	Y57G11C.6	n/a	chrIV 14,759,618	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
50	F48B9.2	F48B9.2	n/a	chrX 2,173,341