UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ZC196.2	ZC196.2	5e-170	chrV 8,740,693	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
2	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
3	C06E4.8	C06E4.8	n/a	chrIV 7,284,853	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
4	C08F11.3	C08F11.3	n/a	chrIV 13,620,866	contains similarity to Homo sapiens HOR5'Beta8; ENSEMBL:ENSP00000332473
5	skr-5	F47H4.10	n/a	chrV 17,348,283	The skr-5 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-5(RNAi) animals are at least superficially normal.
6	srh-193	F47D2.9	n/a	chrV 4,289,288	C. elegans SRH-193 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
7	srw-120	K12D9.5	n/a	chrV 2,995,551	C. elegans SRW-120 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
8	col-114	D2024.8	n/a	chrIV 7,246,056	C. elegans COL-114 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
9	DH11.2	DH11.2	n/a	chrII 8,013,966	contains similarity to Pfam domain PF00646 (F-box domain)
10	F48G7.2	F48G7.2	n/a	chrV 637,034
11	srw-33	T26H5.5	n/a	chrV 15,450,551	C. elegans SRW-33 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300), IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000276 (GPCR, rhodopsin-like)
12	C13A2.3	C13A2.3	n/a	chrV 7,283,523	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
13	srbc-20	C45H4.11	n/a	chrV 2,147,858	C. elegans SRBC-20 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
14	ncx-9	C13D9.8	n/a	chrV 4,993,269	ncx-9 encodes a putative Na[+]/Ca[2+] exchanger of uncertain stoichiometry and affinity, orthologous to human SLC24A6 and paralogous to NCX-6/-8 and NCX-10; NCX-9 may function intracellularly; NCX-9 has tandem Calx-alpha domains predicted to carry out ion transport; NCX-9 has no obvious function in mass RNAi assays.
15	srr-8	C13D9.3	n/a	chrV 5,002,438	C. elegans SRR-8 protein; contains similarity to Pfam domain PF03268 Caenorhabditis protein of unknown function, DUF267 contains similarity to Interpro domain IPR004950 (Protein of unknown function DUF267, Caenorhabditis species)
16	cyp-13A7	T10B9.10	n/a	chrII 9,804,455	cyp-13A7 encodes a homolog of cytochrome P450 proteins; these proteins are membrane proteins with a heme prosthetic group that catalyse the synthesis of steroid hormones (and bile salts), and also detoxify foreign substances (xenobiotic compounds).
17	fbxa-2	T13F3.5	n/a	chrV 16,268,911	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
18	lov-1	ZK945.9	n/a	chrII 10,115,543	lov-1 encodes an ortholog of human PKD1 (OMIM:601313; mutated in autosomal dominant polycystic kidney disease) that is expressed in the ciliated sensory endings of three types of male-specific neurons and that is required for two aspects of male mating behavior: response to hermaphrodite contact and vulva location; LOV-1 acts with PKD-2; EGL-44 and EGL-46 regulate cell-specific expression of lov-1 and pkd-2 to specify the behavioral function of the HOB neuron; in vitro, LOV-1 interacts, via its conserved PLAT domain, with the N-terminus of ATP-2, the beta subunit of ATP synthase that also localizes to cilia, suggesting that ATP synthase may play a role in C. elegans polycystin signaling.
19	F58H7.5	F58H7.5	n/a	chrIV 920,399
20	ttr-2	K03H1.4	n/a	chrIII 9,928,259	K03H1.4 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; the product of K03H1.4 belongs to a family of apparently nematode-specific proteins whose function is not yet known.
21	nas-20	T11F9.3	n/a	chrV 11,471,595	nas-20 encodes an astacin-like metalloprotease.
22	F17C11.4	F17C11.4	n/a	chrV 10,952,702	contains similarity to Mus musculus Desmoglein 2 precursor.; SW:DSG2_MOUSE
23	C07D10.1	C07D10.1	n/a	chrII 7,399,714	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
24	T19D12.3	T19D12.3	n/a	chrII 6,660,581
25	C05D11.13	C05D11.13	n/a	chrIII 6,443,485	contains similarity to Drosophila melanogaster Flybase gene name is CG2839-PA;; FLYBASE:CG2839
26	ocr-3	T10B10.7	n/a	chrX 15,171,101	ocr-3 encodes a predicted TRPV channel (transient receptor potential cation channel, subfamily V) containing six membrane-spanning regions, cytoplasmic ankyrin repeats, and a long, unconserved cytoplasmic tail that is related to the mammalian TRPV1 cation channel (OMIM:602076) activated by capsaicin and other noxious stimuli; although the precise role of OCR-3 in C. elegans development and/or behavior is not yet known, OCR-3 expression is detected solely in the rectal gland cells and occasionally the glial socket cells of the head, suggesting that OCR-3 may function in sensory signal transduction in these cell types.
27	C43F9.4	C43F9.4	n/a	chrIV 10,588,322
28	rhy-1	W07A12.7	n/a	chrII 9,162,328	C. elegans RHY-1 protein; contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
29	C32F10.4	C32F10.4	n/a	chrI 5,809,249
30	spp-6	T08A9.10	n/a	chrX 7,317,449	spp-6 encodes a predicted transmembrane protein containing a saposin (B) domain that is a member of a saposin-like protein superfamily containing mammalian NK-lysin and granulysin and the protozoan amoebapores; SPP-6 is predicted to function as a lipid-binding protein that may possess pore-forming, cytotoxic activity; as loss of SPP-6 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of SPP-6 in C. elegans development and/or behavior is not yet known.
31	Y20C6A.1	Y20C6A.1	n/a	chrV 17,374,108	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
32	ttr-5	C40H1.5	n/a	chrIII 9,330,525	C40H1.5 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; the product of C40H1.5 belongs to a family of apparently nematode-specific proteins whose function is not yet known.
33	F07G11.9	F07G11.9	n/a	chrV 7,317,554	contains similarity to Pfam domains PF01476 (LysM domain) (12), PF05938 (Plant self-incompatibility protein S1) , PF00704 (Glycosyl hydrolases family 18) contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR010264 (Plant self-incompatibility S1), IPR013781 (Glycoside hydrolase, subgroup, catalytic core), IPR001579 (Glycoside hydrolase, chitinase active site), IPR002482 (Peptidoglycan-binding LysM), IPR001002 (Chitin-binding, type 1)
34	C45B2.3	C45B2.3	n/a	chrX 6,083,106
35	Y57G11C.20	Y57G11C.20	n/a	chrIV 14,844,297	contains similarity to Interpro domain IPR000003 ()
36	ttr-1	K03H1.6	n/a	chrIII 9,929,635	ttr-1 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; although TTR-1 belongs to a family of apparently nematode-specific proteins whose function is not yet known, loss of ttr-1 function via RNAi can result in enhanced dauer formation and daf-16-dependent lifespan extension.
37	F58E6.4	F58E6.4	n/a	chrV 9,750,160	contains similarity to Homo sapiens Protein PRO1073/PRO2853; ENSEMBL:ENSP00000332769
38	C03G6.6	C03G6.6	n/a	chrV 7,358,148	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
39	T26H5.8	T26H5.8	n/a	chrV 15,429,911	contains similarity to Pfam domains PF04789 (Protein of unknown function (DUF621)) , PF01748 (Caenorhabditis serpentine receptor-like protein) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR006874 (Protein of unknown function DUF621)
40	F49H6.5	F49H6.5	n/a	chrV 17,024,380	The F49H6.5 gene encodes a homolog of the human gene MOCS1A, which when mutated leads to molybdenum cofactor deficiency (OMIM:252150).
41	grl-23	E02A10.2	n/a	chrV 12,576,078	grl-23 encodes a hedgehog-like protein, with (from N- to C-terminus) a signal sequence, a glycine-rich low-complexity region, a Ground-like (Grl) domain, and an acid-rich low-complexity region; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
42	C11D2.1	C11D2.1	n/a	chrIV 6,191,401
43	ttr-32	R13A5.3	n/a	chrIII 7,566,923	R13A5.3 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; although the product of R13A5.3 belongs to a family of apparently nematode-specific proteins whose function is not yet known, loss of R13A5.3 activity via RNAi has been reported to result in hyperactive locomotion.
44	twk-2	T12C9.3	n/a	chrII 4,447,199	twk-2 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; the precise role of TWK-2 in C. elegans development and/or behavior is not yet known, but TWK-2 may function redundantly with other TWK channels; TWK-2 is expressed in a subset of neurons.
45	D1086.7	D1086.7	n/a	chrV 14,084,866	contains similarity to Synechocystis sp Hypothetical protein slr1028.; TR:P73139
46	F35F10.1	F35F10.1	n/a	chrV 3,317,203	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
47	srab-17	T11A5.2	n/a	chrV 9,867,491	C. elegans SRAB-17 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
48	C25G4.2	C25G4.2	n/a	chrIV 12,443,605	contains similarity to Pfam domain PF03959 Serine hydrolase (FSH1) contains similarity to Interpro domain IPR005645 (Protein of unknown function DUF341)
49	W03F11.1	W03F11.1	n/a	chrI 2,220,892	W03F11.1 encodes a protein with three chitin-binding peritrophin-A domains; like CEJ-1 and CPG-2, W03F11.1 may participate in eggshell synthesis and early embryonic development; W03F11.1 is required for fertility in mass RNAi assays; W03F11.1's multiple peritrophin-A domains might enable mechanical cross-linking of chitin.
50	T14B4.8	T14B4.8	n/a	chrII 6,720,967