UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y7A9D.1	Y7A9D.1	9e-44	chrIV 16,381,762	contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	skr-21	K08H2.1	n/a	chrX 13,226,159	The skr-21 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-21(RNAi) animals are at least superficially normal.
4	col-74	ZK1248.2	n/a	chrII 5,831,409	C. elegans COL-74 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domain IPR008160 (Collagen triple helix repeat)
5	ins-2	ZK75.2	n/a	chrII 5,988,821	ins-2 encodes an insulin-like peptide.
6	F13C5.2	F13C5.2	n/a	chrX 595,125	contains similarity to Pfam domains PF02178 (AT hook motif) , PF00439 (Bromodomain) contains similarity to Interpro domains IPR000116 (High mobility group proteins HMG-I and HMG-Y), IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR001487 (Bromodomain)
7	ceh-43	C28A5.4	n/a	chrIII 4,448,260	A homeobox protein of the Distal-less (Dll) class that is required for development of the anterior hypdermis during embryonic morphogenesis for cell adhesion; also affects embryonic and larval viability; it is predominantly expressed in the head hypdodermis, neuronal support cells and CAN neurons.
8	ZK675.4	ZK675.4	n/a	chrII 7,911,649	contains similarity to Homo sapiens Nuclear pore glycoprotein p62; ENSEMBL:ENSP00000305503
9	C41H7.2	C41H7.2	n/a	chrII 3,015,393	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
10	fbxb-22	Y56A3A.10	n/a	chrIII 11,882,947	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
11	C06G3.6	C06G3.6	n/a	chrIV 7,018,898	contains similarity to Pfam domain PF00569 Zinc finger, ZZ type contains similarity to Interpro domains IPR000315 (Zinc finger, B-box), IPR000433 (Zinc finger, ZZ-type)
12	C05A9.2	C05A9.2	n/a	chrX 10,843,605	contains similarity to Human adenovirus type 4 E3 29.7 kDa protein.; TR:Q8BEL2
13	K08B4.2	K08B4.2	n/a	chrIV 6,075,712
14	C31H5.6	C31H5.6	n/a	chrI 9,045,096	contains similarity to Pfam domains PF08840 (BAAT / Acyl-CoA thioester hydrolase C terminal) , PF04775 (Acyl-CoA thioester hydrolase / Bile acid-CoA amino acid N-acetyltransferase) contains similarity to Interpro domains IPR006862 (Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase), IPR014940 (BAAT/Acyl-CoA thioester hydrolase C-terminal), IPR016662 (Acyl-CoA thioesterase, long chain)
15	F39F10.4	F39F10.4	n/a	chrX 16,903,278
16	R07C3.11	R07C3.11	n/a	chrII 908,164
17	C45B11.2	C45B11.2	n/a	chrV 11,043,313	contains similarity to Pfam domain PF06441 ()
18	fbxb-24	Y56A3A.15	n/a	chrIII 11,909,309	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
19	W10D9.1	W10D9.1	n/a	chrII 454,887
20	fbxb-32	M151.6	n/a	chrII 3,646,198	C. elegans FBXB-32 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
21	cki-1	T05A6.1	n/a	chrII 7,811,601	cki-1 encodes a homolog of the mammalian cyclin-dependent kinase inhibitor p27/KIP1 that is required for the arrest of cell division in larval blast lineages, dauer larvae and starved L1 larvae; excess CKI-1 expression prematurely stops cell division while cki-1(RNAi) induces extra cell divisions, indicating that CKI-1 quantitatively regulates the amount of mitosis in postembryonic worms.
22	col-121	F56D5.1	n/a	chrIV 9,395,553	col-121 encodes a cuticle collagen required for resistance to the endocrine disrupting chemical bisphenol A (BPA); col-121(nx3) and col-121(RNAi) animals are hypersensitive to BPA, but are otherwise wild-type (e.g., they have normal body shape); BPA hypersensitivity has also been observed for dpy-2(e8), dpy-7(e88) and dpy-10(e128) mutants.
23	F31D4.5	F31D4.5	n/a	chrV 20,851,509	contains similarity to Pfam domain PF00169 PH domain contains similarity to Interpro domains IPR001849 (Pleckstrin-like), IPR010997 (HRDC-like), IPR011993 (Pleckstrin homology-type)
24	ZK418.3	ZK418.3	n/a	chrIII 7,070,514	contains similarity to Homo sapiens Transmembrane protein 17; ENSEMBL:ENSP00000335094
25	T04B8.3	T04B8.3	n/a	chrII 628,093	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
26	F13H10.1	F13H10.1	n/a	chrIV 11,004,784	contains similarity to Oryza sativa Putative pM5 collagenase.; TR:Q93W04
27	Y57A10C.1	Y57A10C.1	n/a	chrII 12,411,984	contains similarity to Macaca mulatta Thyrotropin receptor (Fragment).; TR:Q8HY53
28	F42A10.6	F42A10.6	n/a	chrIII 6,176,450
29	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
30	F57A8.1	F57A8.1	n/a	chrV 10,045,776	contains similarity to Interpro domain IPR009058 ()
31	fbxb-10	T08E11.6	n/a	chrII 1,817,843	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
32	EEED8.2	EEED8.2	n/a	chrII 5,417,509	contains similarity to Interpro domains IPR012674 (Calycin), IPR011038 (Calycin-like), IPR000463 (Cytosolic fatty-acid binding)
33	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
34	K02E7.7	K02E7.7	n/a	chrII 1,055,525
35	F53B3.5	F53B3.5	n/a	chrX 2,876,207	F53B3.5 encodes a claudin homolog that may regulate ion channels; F53B3.5 is distantly similar to mammalian voltage-dependent calcium channel gamma subunits that are known or suspected to prevent epilepsy in vivo (e.g., stargazin; MGI:1316660); F53B3.5 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
36	fbxb-16	ZC204.10	n/a	chrII 1,651,202	fbxb-16 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; FBXB-16 also contains a C-terminal type 2 F-box-associated domain of presently unknown function.
37	fbxb-71	F40F4.1	n/a	chrX 3,263,537	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
38	F14H8.2	F14H8.2	n/a	chrV 15,019,750	contains similarity to Sulfolobus solfataricus Heterodisulfite reductase, subunit B (hdrB-1).; TR:Q97Z15
39	F34D6.1	F34D6.1	n/a	chrII 2,680,190	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
40	F20C5.6	F20C5.6	n/a	chrIV 8,772,362	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2DLG0
41	sdz-28	R52.1	n/a	chrII 2,131,740	C. elegans SDZ-28 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
42	C33D9.5	C33D9.5	n/a	chrIV 8,779,611	C33D9.5 encodes a predicted coiled-coil protein; as loss of C33D9.5 activity via large-scale RNAi results in no obvious abnormalities, the precise role of C33D9.5 in C. elegans development and/or behavior is not yet known.
43	F14B4.1	F14B4.1	n/a	chrI 9,268,427	contains similarity to Pfam domains PF00008 (EGF-like domain) (2), PF07645 (Calcium binding EGF domain) , PF00057 (Low-density lipoprotein receptor domain class A) , PF00058 (Low-density lipoprotein receptor repeat class B) (4)contains similarity to Interpro domains IPR000033 (), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR001881 (EGF-like calcium-binding), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR013032 (EGF-like region, conserved site), IPR013091 (EGF calcium-binding), IPR015943 (WD40/YVTN repeat-like)
44	cyp-34A4	T09H2.1	n/a	chrV 3,950,999	C. elegans CYP-34A4 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
45	F38A5.7	F38A5.7	n/a	chrIV 6,602,016
46	unc-42	F58E6.10	n/a	chrV 9,766,975	unc-42 encodes a paired-like homeodomain protein of the Q50 class; UNC-42 is required to specify the fate of ASH sensory neurons, AVA, AVD, and AVE interneurons, and a subset of motor neurons; unc-42 mutants fail to express cell-surface receptors required for differentiated neuronal function (sra-6, srb-6, glr-1, glr-5, and glr-6); UNC-42 is also required for AVKR and HSNL growth cones to follow the PVPR and PVQL pioneer axons, for axonal outgrowth in the backward command interneurons AVA, AVD, and AVE, and for inhibition of ectopic FMRFamide-positive and GABAergic axons; unc-42 mutants are defective in mechanosensation, backward motion, and regulation of egg-laying.
47	T20F5.4	T20F5.4	n/a	chrI 3,914,059
48	fbxb-26	F58E1.3	n/a	chrII 1,683,034	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
49	fbxb-37	T16A1.8	n/a	chrII 2,092,797	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
50	T10B5.4	T10B5.4	n/a	chrV 1,871,195	contains similarity to Pfam domain PF00583 Acetyltransferase (GNAT) family contains similarity to Interpro domains IPR000182 (GCN5-related N-acetyltransferase), IPR016181 (Acyl-CoA N-acyltransferase)