UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y7A5A.2	Y7A5A.2	5e-80	chrX 15,772,148	contains similarity to Aquifex aeolicus Hypothetical protein AQ_372.; SW:Y372_AQUAE
2	twk-20	C40C9.1	n/a	chrX 13,640,987	C. elegans TWK-20 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR013521 (Potassium channel, inwardly rectifying, Kir, conserved region 2), IPR003280 (Potassium channel, two pore-domain), IPR003938 (Potassium channel, voltage-dependent, EAG/ELK/ERG), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
3	T28F12.1	T28F12.1	n/a	chrV 4,514,448
4	gcy-23	T26C12.4	n/a	chrIV 3,286,107	gcy-23 encodes a receptor-type guanylyl cyclase that, along with gcy-8 and gcy-18, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-23 functions redundantly with gcy-8 and gcy-18, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; in addition, loss of gcy-23 activity via RNAi results in lifespan extension; GCY-23 is expressed exclusively in the AFD thermosensory neurons, where it localizes to sensory endings.
5	srt-27	C24B9.6	n/a	chrV 2,720,278	C. elegans SRT-27 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
6	T04F8.3	T04F8.3	n/a	chrX 11,658,991	contains similarity to Staphylococcus phage 44AHJD Hypothetical protein.; TR:Q859L9
7	Y43F8C.13	Y43F8C.13	n/a	chrV 19,691,051	contains similarity to Pfam domain PF01156 Inosine-uridine preferring nucleoside hydrolase contains similarity to Interpro domain IPR001910 (Inosine/uridine-preferring nucleoside hydrolase)
8	C27F2.1	C27F2.1	n/a	chrIII 4,989,295	contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
9	str-129	F58G4.5	n/a	chrV 8,091,709	C. elegans STR-129 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
10	T20H12.1	T20H12.1	n/a	chrII 3,950,365
11	F52B11.5	F52B11.5	n/a	chrIV 14,102,592	contains similarity to Clostridium perfringens Hypothetical protein CPE2159.; TR:Q8XIG1
12	srh-298	Y94A7B.5	n/a	chrV 17,819,902	C. elegans SRH-298 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
13	clec-92	Y52B11A.5	n/a	chrI 11,016,484	C. elegans CLEC-92 protein; contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
14	mec-10	F16F9.5	n/a	chrX 8,467,984	The mec-10 gene encodes an amiloride-sensitive Na+ channel protein (degenerin) required to sense gentle mechanical stimuli (e.g. touch) along the body wall; it is paralogous to mec-4, which has similar function in vivo.
15	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
16	K03B8.8	K03B8.8	n/a	chrV 11,410,221	contains similarity to Interpro domains IPR006030 (Molluscan rhodopsin C-terminal tail), IPR000694 (Proline-rich region)
17	F36A2.2	F36A2.2	n/a	chrI 8,803,215	contains similarity to Pfam domain PF01207 Dihydrouridine synthase (Dus) contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001269 (Dihydrouridine synthase, DuS)
18	C50H11.17	C50H11.17	n/a	chrV 3,097,908	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
19	R08C7.1	R08C7.1	n/a	chrIV 4,451,940
20	T05A7.9	T05A7.9	n/a	chrII 4,684,669	contains similarity to Pfam domain PF01744 GLTT repeat (6 copies) contains similarity to Interpro domain IPR008164 (Repeat of unknown function XGLTT)
21	gcy-37	C54E4.3	n/a	chrIV 2,154,905	gcy-37 encodes a predicted soluble guanylyl cyclase that is expressed in four candidate sensory neurons connected to the pseudocoelom, URXL, URXR, AQR, and PQR; as loss of gcy-37 activity via RNA-mediated interference does not result in any abnormalities, the precise role of GCY-37 in C. elegans development and/or behavior is not yet known; GCY-37 expression in neurons connected to the pseudocoelom suggests, however, that GCY-37 may play a role in fluid homeostasis.
22	lgc-38	F11H8.2	n/a	chrIII 7,014,295	F11H8.2 encodes an UNC-49-like GABA receptor subunit.
23	srt-2	Y45G12C.5	n/a	chrV 2,545,033	C. elegans SRT-2 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
24	Y50F7A.2	Y50F7A.2	n/a	chrII 1,183,626
25	ZC190.6	ZC190.6	n/a	chrV 8,675,924
26	lon-2	C39E6.1	n/a	chrX 4,743,993	lon-2 encodes a member of the glypican family of heparan sulfate proteoglycans; during development, lon-2 activity is required in the hypodermis for negative regulation of the DBL-1/BMP signaling pathway that regulates body length; genetic analyses indicate that lon-2 functions upstream of dbl-1, and in vitro studies show that LON-2 can bind mammalian BMP2, suggesting that LON-2 may directly interact with DBL-1 to negatively regulate DBL-1/BMP signaling; in addition to expression in hypodermis, LON-2 is expressed strongly in the intestine, particularly the anterior and posterior cells; LON-2 localizes to the cell surface.
27	C06B3.7	C06B3.7	n/a	chrV 13,910,615	contains similarity to Streptococcus agalactiae Tn5252, relaxase.; TR:Q8DZ67
28	col-72	W09G10.1	n/a	chrII 3,521,069	C. elegans COL-72 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
29	Y54E2A.2	Y54E2A.2	n/a	chrII 14,750,101	contains similarity to Interpro domain IPR003593 (AAA+ ATPase, core)
30	C17E7.10	C17E7.10	n/a	chrV 3,899,486	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
31	K04A8.3	K04A8.3	n/a	chrV 6,559,849
32	srz-23	F58E2.9	n/a	chrIV 3,454,195	C. elegans SRZ-23 protein ;
33	F11D11.3	F11D11.3	n/a	chrV 18,759,090	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
34	str-149	Y32B12B.5	n/a	chrV 16,574,182	C. elegans STR-149 protein ;
35	ZK1240.8	ZK1240.8	n/a	chrII 2,328,024	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000315 (Zinc finger, B-box)
36	F57E7.1	F57E7.1	n/a	chrV 16,481,775	contains similarity to Bos taurus Enoyl-CoA hydratase precursor (EC 4.2.1.17) (Fragment).; TR:Q95KZ6
37	acr-11	D2092.3	n/a	chrI 6,623,291	A homolog of an alpha type nicotinic acetylcholine receptor subunit involved in the mediation of fast synaptic transmission at neuromuscular junctions.
38	T05B4.10	T05B4.10	n/a	chrV 4,120,294	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
39	F32B5.2	F32B5.2	n/a	chrI 2,698,698
40	srh-60	W10G11.9	n/a	chrII 3,585,242	C. elegans SRH-60 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	tag-96	M01D7.4	n/a	chrI 1,847,837	tag-96 encodes a galactokinase that is a member of the GHMP family of kinases and closely related to the vertebrate galactokinase 2 (GALK2) carbohydrate kinases.
42	ZK262.3	ZK262.3	n/a	chrV 18,415,571	contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domains IPR002921 (Lipase, class 3), IPR008262 (Lipase, active site)
43	C46E10.5	C46E10.5	n/a	chrII 3,712,130
44	str-144	C09H5.5	n/a	chrV 8,071,381	C. elegans STR-144 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	nhr-268	K06B4.6	n/a	chrV 15,690,903	C. elegans NHR-268 protein
46	zig-8	Y39E4B.8	n/a	chrIII 13,126,726	zig-8 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; a zig-8::gfp reporter fusion is expressed in the PVT neuron and in pharyngeal muscle.
47	srh-112	T19C9.2	n/a	chrV 17,225,620	C. elegans SRH-112 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
48	H42K12.2	H42K12.2	n/a	chrX 1,319,512
49	rom-3	Y116A8C.14	n/a	chrIV 16,967,844	C. elegans ROM-3 protein; contains similarity to Pfam domain PF01694 Rhomboid family contains similarity to Interpro domain IPR002610 (Peptidase S54, rhomboid)
50	ncs-1	C44C1.3	n/a	chrX 961,929	The ncs-1 gene encodes a neuronal calcium sensor protein that, along with calcium, is essential for thermotaxis along isothermal paths in thermal gradients.