UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y75B8A.4	Y75B8A.4	0	chrIII 12,110,492	contains similarity to Pfam domains PF07726 (ATPase family associated with various cellular activities (AAA)) , PF00004 (ATPase family associated with various cellular activities (AAA)) , PF05362 (Lon protease (S16) C-terminal proteolytic domain) , PF07728 (ATPase family associated with various cellular activities (AAA)) contains similarity to Interpro domains IPR003959 (AAA ATPase, core), IPR000767 (Disease resistance protein), IPR011704 (ATPase associated with various cellular activities, AAA-5), IPR011703 (ATPase associated with various cellular activities, AAA-3), IPR004815 (Peptidase S16, ATP-dependent protease La), IPR008269 (Peptidase S16, lon C-terminal), IPR003111 (Peptidase S16, lon N-terminal), IPR003593 (AAA+ ATPase, core), IPR001984 (Peptidase S16, Lon protease)
2	F21C10.7	F21C10.7	n/a	chrV 9,117,429	contains similarity to Pfam domains PF07686 (Immunoglobulin V-set domain) (2), PF00047 (Immunoglobulin domain) (3), PF07679 (Immunoglobulin I-set domain) (6)contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR002017 (Spectrin repeat), IPR013098 (Immunoglobulin I-set), IPR013783 (Immunoglobulin-like fold), IPR013106 (Immunoglobulin V-set), IPR007110 (Immunoglobulin-like), IPR003599 (Immunoglobulin subtype), IPR013151 (Immunoglobulin)
3	C10C5.1	C10C5.1	n/a	chrIV 9,362,924	contains similarity to Drosophila melanogaster Flybase gene name is CG8486-PA;; FLYBASE:CG8486
4	gst-38	F35E8.8	n/a	chrV 15,915,638	C. elegans GST-38 protein; contains similarity to Pfam domain PF02798 Glutathione S-transferase, N-terminal domain contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
5	F27E5.3	F27E5.3	n/a	chrII 10,142,746	contains similarity to Homo sapiens Isoform 1 of Cell division cycle 2-related protein kinase 7; ENSEMBL:ENSP00000300647
6	T20B3.1	T20B3.1	n/a	chrV 16,818,064	contains similarity to Pfam domain PF00755 Choline/Carnitine o-acyltransferase contains similarity to Interpro domain IPR000542 (Acyltransferase ChoActase/COT/CPT)
7	pqn-95	ZK1067.7	n/a	chrII 9,226,126	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
8	pqn-5	C03A7.4	n/a	chrV 5,159,245	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
9	pgp-3	ZK455.7	n/a	chrX 11,354,551	pgp-3 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; with PGP-1, PGP-3 is required for defense against the pathogenic Pseudomonas aeruginosa strain PA14, and may facilitate ATP-dependent efflux of the toxic phenazine compounds produced by the bacteria; PGP-3 is also required for resistance to colchicine and chloroquine; PGP-3 is expressed in the apical membranes of the excretory cell and the intestinal cells; loss of pgp-3 activity via large-scale RNAi screens does not result in any obvious abnormalities.
10	nhr-45	F16H11.5	n/a	chrX 4,658,348	C. elegans NHR-45 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
11	gex-2	F56A11.1	n/a	chrIV 578,227	The gex-2 gene encodes a homolog of p140/Sra-1, a mammalian protein ligand of the small GTPase Rac1; gex-2 is required for tissue morphogenesis and cell migrations.
12	C49C3.4	C49C3.4	n/a	chrIV 17,324,683	contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR013032 (EGF-like region, conserved site)
13	gst-14	F37B1.3	n/a	chrII 13,615,382	C. elegans GST-14 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
14	C25D7.5	C25D7.5	n/a	chrV 15,054,998	contains similarity to Pfam domain PF00753 (Metallo-beta-lactamase superfamily)
15	fipr-20	H14A12.6	n/a	chrIII 7,462,256	C. elegans FIPR-20 protein ;
16	T06E4.9	T06E4.9	n/a	chrV 9,620,523	contains similarity to Interpro domain IPR000694 (Proline-rich region)
17	B0272.4	B0272.4	n/a	chrX 9,429,267	contains similarity to Pfam domain PF00378 Enoyl-CoA hydratase/isomerase family contains similarity to Interpro domain IPR001753 (Crotonase, core)
18	col-69	K01A2.7	n/a	chrII 304,726	C. elegans COL-69 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
19	hex-2	C14C11.3	n/a	chrV 5,656,509	hex-2 encodes a beta-N-acetylhexosaminidase.
20	ldh-1	F13D12.2	n/a	chrII 11,725,839	ldh-1 is orthologous to the human gene LACTATE DEHYDROGENASE B (LDHB; OMIM:150100), which when mutated leads to lactate dehydrogenase-B deficiency.
21	Y75B8A.13	Y75B8A.13	n/a	chrIII 12,209,672	contains similarity to Interpro domain IPR000694 (Proline-rich region)
22	gei-18	Y37A1B.15	n/a	chrIV 13,981,773	C. elegans GEI-18 protein ;
23	gbf-1	C24H11.7	n/a	chrIII 11,762,525	C. elegans GBF-1 protein; contains similarity to Pfam domain PF01369 Sec7 domain contains similarity to Interpro domains IPR008979 (Galactose-binding like), IPR000904 (SEC7-like)
24	pgp-1	K08E7.9	n/a	chrIV 12,595,402	pgp-1 encodes a transmembrane protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; along with PGP-3, PGP-1 is required for defense against the pathogenic Pseudomonas aeruginosa strain PA14, and may facilitate ATP-dependent efflux of the toxic phenazine compounds produced by the bacteria; PGP-1 is expressed in the apical membrane of intestinal cells and in the intestinal valve cells; loss of pgp-1 activity via large-scale RNAi screens does not result in any obvious abnormalities.
25	twk-42	W06D12.2	n/a	chrV 17,728,557	C. elegans TWK-42 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2)
26	pqn-74	W02A2.3	n/a	chrIV 13,330,430	pqn-74 encodes a protein with two chitin-binding peritrophin-A domains, separated by a glutamine/asparagine (Q/N)-rich ('prion') domain; like CEJ-1 and CPG-2, PQN-74 might participate in eggshell synthesis and early embryonic development, and PQN-74's peritrophin-A domains might enable mechanical cross-linking of chitin.
27	K07E3.1	K07E3.1	n/a	chrX 8,112,540	contains similarity to Trichomonas vaginalis G3 Dentin sialophosphoprotein, putative.; TR:A2DMT3
28	VT23B5.1	VT23B5.1	n/a	chrIV 12,665,034	contains similarity to Homo sapiens Isoform 2 of WD repeat and FYVE domain-containing protein 3; ENSEMBL:ENSP00000318466
29	cyp-33A1	C12D5.7	n/a	chrV 7,680,386	C. elegans CYP-33A1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
30	wrt-3	F38E11.7	n/a	chrIV 9,476,571	wrt-3 encodes a hedgehog-like protein, with an N-terminal signal sequence, a Wart domain, and a region of low-complexity sequence; WRT-3 is expressed in the trinucleate pharyngeal gland cell g1 beginning at the three-fold stage of embryogenesis, in seam cells and hypodermis, and in single muscle cells and the distal tip cells of late stage larvae and adults; the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-3 is required for normal growth to full size and locomotion; both of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
31	F42A10.3	F42A10.3	n/a	chrIII 6,156,244	contains similarity to Pfam domain PF01234 NNMT/PNMT/TEMT family contains similarity to Interpro domain IPR000940 (Methyltransferase, NNMT/PNMT/TEMT)
32	R06B10.1	R06B10.1	n/a	chrIII 969,326	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR003125 (Protein of unknown function WSN)
33	prp-8	C50C3.6	n/a	chrIII 8,168,465	prp-8 is orthologous to the human gene SIMILAR TO U5 SNRNP-SPECIFIC PROTEIN (220 KD), ORTHOLOG OF S.
34	abu-10	F35A5.3	n/a	chrX 3,798,945	abu-10 encodes a transmembrane protein with a predicted signal sequence, a glutamine/asparagine-rich domain and a cysteine-rich repeat (DUF139); abu-10 expression is induced by blockage of the unfolded-protein response in the endoplasmic reticulum (ER), and ABU-10 may function within the ER to protect the organism from damage by improperly folded nascent protein.
35	gst-20	Y48E1B.10	n/a	chrII 13,608,893	C. elegans GST-20 protein; contains similarity to Pfam domain PF02798 Glutathione S-transferase, N-terminal domain contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
36	prx-13	F32A5.6	n/a	chrII 7,251,051	prx-13 is orthologous to the human gene PEX13 (OMIM:601789), which when mutated leads to Zellweger syndrome or neonatal adrenoleukodystrophy.
37	R08C7.5	R08C7.5	n/a	chrIV 4,431,281	contains similarity to Pfam domain PF03941 Inner centromere protein, ARK binding region contains similarity to Interpro domains IPR005819 (Histone H5), IPR005635 (Inner centromere protein, ARK binding region)
38	F55B11.1	F55B11.1	n/a	chrIV 14,406,976	The F55B11.1 gene encodes an ortholog of the human gene XANTHINE DEHYDROGENASE (XDH), which when mutated leads to xanthinuria (OMIM:278300).
39	F54D10.3	F54D10.3	n/a	chrII 3,812,819	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domains IPR000976 (Wilm's tumour protein), IPR005020 (Protein of unknown function DUF278)
40	W09C5.8	W09C5.8	n/a	chrI 13,658,783	contains similarity to Pfam domain PF02936 Cytochrome c oxidase subunit IV contains similarity to Interpro domains IPR013288 (Cytochrome c oxidase subunit 4), IPR004203 (Cytochrome c oxidase subunit IV)
41	B0303.14	B0303.14	n/a	chrIII 8,714,993	contains similarity to Homo sapiens 33 kDa protein; VG:OTTHUMP00000025234
42	abt-4	Y39D8C.1	n/a	chrV 327,261	abt-4 encodes a predicted ATP-binding cassette (ABC) transporter that is a member of the ABCA subfamily of transport proteins; ABT-4 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of abt-4 activity via RNAi results in no obvious defects, the precise role of abt-4 in C. elegans development and/or behavior is not yet known; abt-4 promoter-gfp fusion proteins are widely expressed in larvae and adults, with expression seen in the pharynx, the pharyngeal-intestinal valve, the intestine, renal gland cells, hypodermis, various neurons, and unidentified cells in the head and tail.
43	Y48A6B.10	Y48A6B.10	n/a	chrIII 11,041,221	contains similarity to Interpro domain IPR000694 (Proline-rich region)
44	F38E1.9	F38E1.9	n/a	chrV 8,358,662	contains similarity to Pfam domain PF04193 PQ loop repeat contains similarity to Interpro domains IPR006603 (Cystinosin/ERS1p repeat), IPR016817 (Mannose-P-dolichol utilization defect 1 protein)
45	clec-64	F35C5.7	n/a	chrII 12,899,255	C. elegans CLEC-64 protein; contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002035 (von Willebrand factor, type A)
46	abu-7	C03A7.8	n/a	chrV 5,164,061	abu-7 encodes a transmembrane protein with a predicted signal sequence, a glutamine/asparagine-rich domain and multiple cysteine-rich repeats (DUF139); abu-7 expression is induced by blockage of the unfolded-protein response in the endoplasmic reticulum, and ABU-7 may help protect the organism from damage by improperly folded nascent protein.
47	T01E8.5	T01E8.5	n/a	chrII 10,245,041	contains similarity to Pfam domain PF08424 Protein of unknown function (DUF1740) contains similarity to Interpro domain IPR013633 (Protein of unknown function DUF1740)
48	D2089.2	D2089.2	n/a	chrII 10,660,588	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
49	fbxa-90	Y102A5C.19	n/a	chrV 16,967,704	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
50	ugt-51	C03A7.11	n/a	chrV 5,176,130	C. elegans UGT-51 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)