UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y6G8.2	Y6G8.2	0	chrV 17,596,508	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	F09C12.6	F09C12.6	n/a	chrII 5,117,137	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
4	pah-1	K08F8.4	n/a	chrII 8,763,866	pah-1 encodes a biochemically active phenylalanine-4-hydroxylase orthologous to human PAH (OMIM:261600, mutated in phenylketonuria); recombinant PAH-1 has hydroxylase activity on phenylalanine and tryptophan substrates in vitro; pah-1 is expressed in seam cells, tail hypodermal cells, and ventral hypodermis, with stronger posterior than anterior expression; PAH-1 might help provide tyrosine for cross-linking in the cuticle, and is partially required for the tyrosinemic phenotype of K10C2.4(RNAi) animals.
5	F13H8.2	F13H8.2	n/a	chrII 6,272,139	contains similarity to Pfam domains PF04003 (Dip2/Utp12 Family) , PF00400 (WD domain, G-beta repeat) (8)contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR007148 (Small-subunit processome, Utp12), IPR015943 (WD40/YVTN repeat-like)
6	hgo-1	W06D4.1	n/a	chrI 9,052,445	hgo-1 encodes a putative homogentisate 1,2-dioxygenase, orthologous to human HGD (OMIM:607474, mutated in alkaptonuria), that is required for normal resistance to hypertonic stress; HGO-1 is expressed in larval and adult hypodermis and intestine, and in larval pharynx; HGO-1 is required for the tyrosinemic phenotype of K10C2.4(RNAi) animals.
7	W02D9.10	W02D9.10	n/a	chrI 12,551,930
8	prx-2	ZK809.7	n/a	chrIV 11,645,165	prx-2 is orthologous to the human gene PEROXISOMAL MEMBRANE PROTEIN 3 (PXMP3; OMIM:170993), which when mutated leads to Zellweger syndrome 3 or infantile Refsum disease.
9	cal-1	C13C12.1	n/a	chrV 12,515,481	cal-1 encodes one of five predicted C. elegans calcium-binding calmodulin homologs (the others being CAL-2, CAL-3, CAL-4, and CMD-1); as loss of cal-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of CAL-1 in C. elegans development and/or behavior is not yet known.
10	srr-9	T05B11.2	n/a	chrV 7,738,784	C. elegans SRR-9 protein; contains similarity to Pfam domain PF03268 Caenorhabditis protein of unknown function, DUF267 contains similarity to Interpro domain IPR004950 (Protein of unknown function DUF267, Caenorhabditis species)
11	F37C4.8	F37C4.8	n/a	chrIV 3,880,246
12	tag-225	K07C11.5	n/a	chrV 8,202,146	K07C11.5 is orthologous to the human gene SIMILAR TO TISSUE INHIBITOR OF METALLOPROTEINASE 3 (SORSBY FUNDUS DYSTROPHY, PSEUDOINFLAMMATORY) (TIMP3; OMIM:188826), which when mutated leads to disease.
13	btb-21	F47C10.2	n/a	chrV 3,850,930	C. elegans BTB-21 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
14	rcn-1	F54E7.7	n/a	chrIII 5,683,173	rcn-1 encodes a calcipressin, which binds and inhibits calcineurin; RCN-1's orthologs include yeast Rcn1p and human DSCR1 (OMIM:602917; overexpressed in Down syndrome and Alzheimer disease); rcn-1 is expressed in hypodermal seam cells, various neurons, vulval epithelial and muscle cells, marginal pharyngeal cells, and in the male tail; rcn-1 transcription is regulated by TAX-6, and RCN-1 binds TAX-6 protein if free Ca[2+] is present; RCN-1 overexpression, like calcineurin deficiency, causes defects in body size, cuticle thickness, fertility, growth rate, and serotonin-resistance in egg-laying.
15	Y2H9A.4	Y2H9A.4	n/a	chrV 13,447,397	contains similarity to Pfam domain PF05218 Protein of unknown function (DUF713) contains similarity to Interpro domains IPR007883 (Protein of unknown function DUF713), IPR005398 (Tubby, N-terminal)
16	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
17	F47D12.3	F47D12.3	n/a	chrIII 6,298,853	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
18	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
19	glb-22	R11H6.3	n/a	chrV 14,605,162	glb-22 encodes a globin with no obvious function in mass RNAi assays.
20	C54A12.2	C54A12.2	n/a	chrII 5,254,604	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B), IPR000276 (GPCR, rhodopsin-like)
21	F49C12.6	F49C12.6	n/a	chrIV 9,308,209	contains similarity to Pfam domains PF06800 (Sugar transport protein) , PF07857 (CEO family (DUF1632)) contains similarity to Interpro domains IPR012435 (Protein of unknown function DUF1632), IPR010651 (Sugar transport), IPR005384 (Duffy antigen/chemokine receptor)
22	F22F1.2	F22F1.2	n/a	chrX 8,150,103	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
23	F21D12.5	F21D12.5	n/a	chrII 7,329,535	contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
24	F31E8.1	F31E8.1	n/a	chrII 6,829,225
25	C33F10.1	C33F10.1	n/a	chrII 4,835,359
26	Y76A2B.5	Y76A2B.5	n/a	chrIII 13,547,827	contains similarity to Danio rerio Zgc:91819 protein.; TR:Q6GMH4
27	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
28	srg-17	F15A4.7	n/a	chrII 12,474,385	C. elegans SRG-17 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
29	bath-26	T07H3.6	n/a	chrII 1,600,097	C. elegans BATH-26 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
30	tag-196	F41E6.6	n/a	chrV 8,596,111	C. elegans TAG-196 protein; contains similarity to Pfam domains PF08246 (Cathepsin propeptide inhibitor domain (I29)) , PF00112 (Papain family cysteine protease) , PF00031 (Cystatin domain) contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000010 (Proteinase inhibitor I25, cystatin), IPR000169 (Peptidase, cysteine peptidase active site), IPR013201 (Proteinase inhibitor I29, cathepsin propeptide), IPR000668 (Peptidase C1A, papain C-terminal)
31	clec-201	C30H6.3	n/a	chrIV 17,359,724	C. elegans CLEC-201 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
32	C34B2.3	C34B2.3	n/a	chrI 10,673,805	contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase)
33	M04D8.7	M04D8.7	n/a	chrIII 10,037,728	contains similarity to Sulfolobus tokodaii Putative cytochrome o ubiquinol oxidase assembly factor.; TR:Q970T4
34	Y51B9A.9	Y51B9A.9	n/a	chrII 9,396,480	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR008351 (JNK MAP kinase), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
35	F25H9.2	F25H9.2	n/a	chrV 13,458,772	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
36	B0507.2	B0507.2	n/a	chrV 8,775,382	contains similarity to Interpro domain IPR004328 (BRO1)
37	Y37D8A.6	Y37D8A.6	n/a	chrIII 12,857,304	contains similarity to Interpro domains IPR006629 (LPS-induced tumor necrosis factor alpha factor), IPR013032 (EGF-like region, conserved site)
38	C49D10.8	C49D10.8	n/a	chrII 3,859,527	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
39	H32K16.1	H32K16.1	n/a	chrI 9,151,388	contains similarity to Pfam domain PF01490 Transmembrane amino acid transporter protein contains similarity to Interpro domain IPR013057 (Amino acid transporter, transmembrane)
40	C47E12.9	C47E12.9	n/a	chrIV 9,975,041	contains similarity to Homo sapiens Hypothetical protein; ENSEMBL:ENSP00000265840
41	srx-20	R13H7.1	n/a	chrIV 6,868,598	C. elegans SRX-20 protein ;
42	ZK822.4	ZK822.4	n/a	chrIV 11,927,183	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
43	twk-9	ZK1251.8	n/a	chrIV 9,695,064	C. elegans TWK-9 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2)
44	F16H6.7	F16H6.7	n/a	chrV 18,208,098	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
45	Y11D7A.10	Y11D7A.10	n/a	chrIV 9,259,330	contains similarity to Coniophora arida ATP synthase subunit 6 (EC 3.6.3.14) (ATP synthase A chain)s(Fragment).; TR:Q9XLN6
46	M01B2.6	M01B2.6	n/a	chrV 15,242,739	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
47	C33C12.7	C33C12.7	n/a	chrII 2,174,952
48	K11G9.5	K11G9.5	n/a	chrV 6,687,134	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
49	T22F7.4	T22F7.4	n/a	chrIII 526,147
50	F21C10.4	F21C10.4	n/a	chrV 9,127,111	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)