UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y57G11C.31	Y57G11C.31	0	chrIV 14,685,186	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domain IPR005069 (Protein of unknown function DUF271)
2	tag-123	F08F1.7	n/a	chrX 8,420,290	C. elegans TAG-123 protein; contains similarity to Pfam domain PF02990 Endomembrane protein 70 contains similarity to Interpro domains IPR008075 (Lipocalin-1 receptor), IPR004240 (Nonaspanin (TM9SF))
3	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
4	col-73	F11G11.12	n/a	chrII 4,872,607	C. elegans COL-73 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR000596 (Cholecystokinin receptor, type A), IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
5	R07C12.2	R07C12.2	n/a	chrIV 4,149,092
6	nhr-165	C47F8.2	n/a	chrI 12,332,239	C. elegans NHR-165 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
7	F13A2.6	F13A2.6	n/a	chrV 4,403,625	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
8	F44D12.1	F44D12.1	n/a	chrIV 10,012,047	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domains IPR008144 (Guanylate kinase), IPR008145 (Guanylate kinase/L-type calcium channel region), IPR001452 (Src homology-3), IPR001478 (PDZ/DHR/GLGF)
9	R07B7.8	R07B7.8	n/a	chrV 12,082,679	contains similarity to Pfam domain PF00657 GDSL-like Lipase/Acylhydrolase contains similarity to Interpro domains IPR001087 (Lipase, GDSL), IPR013830 (Esterase, SGNH hydrolase-type)
10	math-21	C40D2.3	n/a	chrII 1,994,852	C. elegans MATH-21 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
11	M57.1	M57.1	n/a	chrIV 3,536,339	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
12	K08C9.7	K08C9.7	n/a	chrI 11,495,873	contains similarity to Homo sapiens ubiquitin and ribosomal protein S27a precursor; ENSEMBL:ENSP00000272317
13	C03F11.2	C03F11.2	n/a	chrX 5,395,712	contains similarity to Pfam domain PF00753 Metallo-beta-lactamase superfamily contains similarity to Interpro domain IPR001279 (Beta-lactamase-like)
14	R09D1.8	R09D1.8	n/a	chrII 9,460,970	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
15	unc-50	T07A5.2	n/a	chrIII 10,316,260	unc-50 encodes an integral membrane protein orthologous to the Saccharomyces cerevisiae Golgi component Gmh1p; UNC-50 is required for regulating subtype-specific nicotinic receptor trafficking to the cell surface and thus, for normal synaptic transmission at the neuromuscular junction; UNC-50 is ubiquitously expressed from early embryogenesis to adulthood and localizes to the Golgi.
16	C32E8.11	C32E8.11	n/a	chrI 3,812,136	contains similarity to Pfam domains PF02617 (ATP-dependent Clp protease adaptor protein ClpS) , PF02207 (Putative zinc finger in N-recognin (UBR box)) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013993 (Zinc finger, N-recognin, metazoa), IPR014719 (Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like), IPR003126 (Zinc finger, N-recognin), IPR000315 (Zinc finger, B-box), IPR003769 (Adaptor protein ClpS, core)
17	F57B10.5	F57B10.5	n/a	chrI 6,563,176	contains similarity to Pfam domain PF01105 emp24/gp25L/p24 family/GOLD contains similarity to Interpro domains IPR009038 (GOLD), IPR000348 (emp24/gp25L/p24)
18	AC8.7	AC8.7	n/a	chrX 230,898
19	F40E3.2	F40E3.2	n/a	chrI 2,643,222
20	nas-1	F45G2.1	n/a	chrIII 13,407,525	nas-1 encodes an astacin-like metalloprotease.
21	ZK1086.2	ZK1086.2	n/a	chrX 13,792,979	contains similarity to Shewanella oneidensis Hypothetical protein.; TR:Q8EJA6
22	dpy-1	M01E10.2	n/a	chrIII 2,041,006	dpy-1 encodes a collagen that affects body length and alae formation; site of action localized to the hyp7 syncytium, based on mosaic analysis.
23	cul-5	ZK856.1	n/a	chrV 10,181,305	cul-5 encodes a cullin, orthologous to vasopressin-activated calcium-mobilizing receptor-1 in mammals, that is thought to regulate the cell cycle by virtue of its paralogy to cul-1 and cul-2; however, CUL-5 is dispensable for viability and gross morphology in mass RNAi screens, and does not appear to interact with any of 17 Skp1-related proteins (SKR-1 through SKR-21).
24	C50D2.2	C50D2.2	n/a	chrII 110,283	contains similarity to Pfam domain PF00324 Amino acid permease contains similarity to Interpro domains IPR004841 (Amino acid permease-associated region), IPR002293 (Amino acid/polyamine transporter I)
25	B0399.2	B0399.2	n/a	chrV 19,551,938	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
26	srv-11	H25K10.3	n/a	chrIV 16,220,615	C. elegans SRV-11 protein; contains similarity to Pfam domains PF01461 (7TM chemoreceptor) , PF01748 (Caenorhabditis serpentine receptor-like protein) contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002651 (Protein of unknown function DUF32)
27	F35D2.1	F35D2.1	n/a	chrII 7,577,252
28	hum-6	T10H10.1	n/a	chrX 2,309,009	hum-6 is orthologous to the human gene MYOSIN VIIA (MYO7A; OMIM:276903), which when mutated leads to Usher syndrome type IB.
29	T25G3.4	T25G3.4	n/a	chrI 7,566,145	T25G3.4 encodes a putative mitochondrial glycerol-3-phosphate dehydrogenase, paralogous to Y50E8A.6 and orthologous to human GPD2 (OMIM:138430, mutated in type II diabetes mellitus); T25G3.4 transcripts are not obviously enriched during oogenesis, but T25G3.4 is predicted to be coexpressed in an operon with chs-1 and T25G3.3; such coexpression, if real, may simply reflect all three genes being required for oogenesis, rather than some more detailed functional connection; T25G3.4 has no obvious function in mass RNAi assays.
30	F49B2.3	F49B2.3	n/a	chrI 14,311,927	contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR000694 (Proline-rich region)
31	T01B10.5	T01B10.5	n/a	chrX 8,496,580
32	T08G2.2	T08G2.2	n/a	chrX 17,207,313	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
33	C24A3.4	C24A3.4	n/a	chrX 8,993,472	contains similarity to Pfam domain PF02515 CoA-transferase family III contains similarity to Interpro domains IPR016160 (Aldehyde dehydrogenase, conserved site), IPR003673 (CoA-transferase family III)
34	C39H7.4	C39H7.4	n/a	chrIV 5,613,304
35	R05H10.5	R05H10.5	n/a	chrII 14,868,296	contains similarity to Pfam domain PF00255 Glutathione peroxidase contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR000889 (Glutathione peroxidase)
36	tra-3	LLC1.1	n/a	chrIV 14,440,241	tra-3 encodes an atypical calpain regulatory protease that lacks calcium-binding EF hand domains; during development, TRA-3 likely promotes female development in XX hermaphrodites by cleaving the membrane-associated TRA-2A protein to generate a TRA-2 peptide likely to have feminizing activity; in addition, TRA-3 is one of several proteases that mediate necrotic cell death during neurodegeneration.
37	F15D4.6	F15D4.6	n/a	chrII 13,249,439	contains similarity to Bacillus halodurans Acetolactate synthase large subunit.; TR:Q9K8E5
38	F53B3.2	F53B3.2	n/a	chrX 2,860,247	contains similarity to Pfam domain PF01596 O-methyltransferase contains similarity to Interpro domain IPR002935 (O-methyltransferase, family 3)
39	F55A4.5	F55A4.5	n/a	chrX 1,031,456	contains similarity to Pfam domain PF00035 Double-stranded RNA binding motif contains similarity to Interpro domains IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like)
40	ZC513.1	ZC513.1	n/a	chrV 8,056,969	contains similarity to Pfam domain PF02886 LBP / BPI / CETP family, C-terminal domain contains similarity to Interpro domain IPR001124 (Lipid-binding serum glycoprotein)
41	srx-36	T01C4.6	n/a	chrV 7,130,371	C. elegans SRX-36 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
42	F18F11.4	F18F11.4	n/a	chrIV 332,622	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
43	crb-1	F11C7.4	n/a	chrX 17,408,117	crb-1 encodes a homolog of Drosophila CRUMBS that affects dauer formation and feeding behavior; CRB-1 can bind cyclic AMP-response element (CRE) sites and be phosphorylated by PKA in vitro, and is expressed immediately apical to the zonula adherens in embryos and then ubiquitously later during development and in adults; CRB-1 is homologous to human CRB1 (OMIM:604210, mutated in retinitis pigmentosa 12 or Leber congenital amaurosis).
44	fbxa-166	C08E3.9	n/a	chrII 1,617,962	C. elegans FBXA-166 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
45	F41E6.12	F41E6.12	n/a	chrV 8,627,981
46	C24H10.2	C24H10.2	n/a	chrX 5,065,438
47	K08C9.5	K08C9.5	n/a	chrI 11,483,971	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
48	sph-1	F42G8.11	n/a	chrIV 8,132,914	sph-1 encodes a member of the synaptophysin/synaptoporin family that contains a MARVEL domain, a membrane-associating domain found in lipid-associating proteins, and contains a transmembrane domain.
49	F54B3.2	F54B3.2	n/a	chrII 10,269,583	contains similarity to Schizosaccharomyces pombe Hypothetical protein.; TR:Q9UT52
50	cdc-42	R07G3.1	n/a	chrII 7,617,275	cdc-42 encodes a RHO GTPase which controls polarity of both individual cells and developing embryos by regulating the localization of PAR proteins; CDC-42 is expressed at hypodermal cell boundaries; cdc-42 expression levels are unusually stable, with relatively little variation between adults, dauers, and L3 larvae, or between wild-type and daf-2(e1370ts) or daf-16(m26) mutant adults.