UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	hhat-2	Y57G11C.17	0	chrIV 14,827,743	C. elegans HHAT-2 protein; contains similarity to Pfam domain PF03062 MBOAT family contains similarity to Interpro domain IPR004299 (Membrane bound O-acyl transferase, MBOAT)
2	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
3	clec-9	Y70C5C.2	n/a	chrV 16,705,835	C. elegans CLEC-9 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
4	F16D3.6	F16D3.6	n/a	chrI 8,376,505	contains similarity to Pfam domain PF06681 Protein of unknown function (DUF1182) contains similarity to Interpro domains IPR002091 (Aromatic amino acid permease), IPR010601 (Protein of unknown function DUF1182)
5	T21B10.3	T21B10.3	n/a	chrII 8,936,627	contains similarity to Homo sapiens Conserved hypothetical protein; VG:OTTHUMP00000076919
6	K02E10.7	K02E10.7	n/a	chrX 2,504,770	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
7	C07E3.8	C07E3.8	n/a	chrII 10,352,798	contains similarity to Pfam domain PF06542 Protein of unknown function (DUF1114) contains similarity to Interpro domain IPR009497 (Protein of unknown function DUF1114)
8	gcy-36	C46E1.2	n/a	chrX 15,482,280	gcy-36 encodes a predicted soluble guanylate cyclase that genetically interacts with npr-1 with respect to feeding behavior; expressed in AQR, PQR, and URX3.
9	sir-2.3	F46G10.3	n/a	chrX 13,332,774	C. elegans SIR-2.3 protein; contains similarity to Pfam domain PF02146 Sir2 family contains similarity to Interpro domain IPR003000 (NAD-dependent histone deacetylase, silent information regulator Sir2)
10	osm-1	T27B1.1	n/a	chrX 16,546,188	osm-1 encodes a WD- and WAA-repeat containing protein that is the C. elegans ortholog of intraflagellar transport (IFT) complex B component IFT172; OSM-1 is a presumptive cargo molecule for kinesin-II, and OSM-1 is required, along with OSM-6, for the proper assembly of the middle segments of sensory cilia; osm-1 may act in a pathway with avr-14 to affect resistance to ivermectin-induced cessation of pumping, and mutants are defective in avoidance of solutions of high osmotic strength; an OSM-1::GFP fusion protein is expressed in amphid and phasmid chemosensory neurons where it undergoes both anterograde and retrograde intraflagellar transport.
11	T24D8.6	T24D8.6	n/a	chrX 2,365,815
12	hlh-27	C17C3.10	n/a	chrII 5,540,531	C. elegans HLH-27 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
13	fbxa-154	B0391.6	n/a	chrV 15,603,958	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
14	F56F11.5	F56F11.5	n/a	chrIII 2,853,197
15	M01H9.2	M01H9.2	n/a	chrIV 4,461,106	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR002350 (Proteinase inhibitor I1, Kazal), IPR001368 (TNFR/CD27/30/40/95 cysteine-rich region), IPR003582 (Metridin-like ShK toxin)
16	F59E10.3	F59E10.3	n/a	chrII 10,873,252	F59E10.3 encodes a zeta subunit of the coatomer (COPI) complex; in mass RNAi assays, F59E10.3 is required for embryonic, larval, and adult viability, for fertility, and for normal osmoregulation.
17	srt-71	C50H11.3	n/a	chrV 3,084,429	C. elegans SRT-71 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR002208 (SecY protein)
18	srx-23	F31F4.2	n/a	chrV 683,114	C. elegans SRX-23 protein ;
19	F53A2.1	F53A2.1	n/a	chrIII 13,321,932	contains similarity to Pfam domain PF06542 Protein of unknown function (DUF1114) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR009497 (Protein of unknown function DUF1114), IPR009010 (Aspartate decarboxylase-like fold)
20	hlh-10	ZK682.4	n/a	chrV 9,281,043	C. elegans HLH-10 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
21	T27A1.3	T27A1.3	n/a	chrII 536,941	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
22	B0034.5	B0034.5	n/a	chrII 5,973,873	contains similarity to Interpro domain IPR000276 (GPCR, rhodopsin-like)
23	F28G4.4	F28G4.4	n/a	chrV 16,284,328	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domains IPR017853 (Glycoside hydrolase, catalytic core), IPR005069 (Protein of unknown function DUF271)
24	ace-2	Y44E3A.2	n/a	chrI 3,304,491	An acetylcholineesterase involved in the termination of cholinergic nerve transmission; it is predominantly expressed in motoneurons.
25	Y75B8A.6	Y75B8A.6	n/a	chrIII 12,127,086	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
26	ins-35	K02E2.4	n/a	chrV 20,371,307	ins-35 encodes one of several insulin-related peptides.
27	T15B7.14	T15B7.14	n/a	chrV 6,833,799
28	gcy-19	C17F4.6	n/a	chrII 3,254,897	gcy-19 encodes a predicted transmembrane guanylyl cyclase; as loss of gcy-19 activity via RNA-mediated interference does not result in any abnormalities, the precise role of GCY-19 in C. elegans development and/or behavior is not yet known; by sequence similarity, however, GCY-19 can be predicted to function in chemosensory signal transduction.
29	srsx-17	F58D7.1	n/a	chrV 5,929,015	C. elegans SRSX-17 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
30	tsp-8	F33C8.3	n/a	chrX 14,727,975	tsp-8 is orthologous to the human gene KANGAI 1 (SUPPRESSION OF TUMORIGENICITY 6, PROSTATE; CD82 ANTIGEN (R2 LEUKOCYTE ANTIGEN, ANTIGEN DETECTED BY MONOCLONAL AND ANTIBODY IA4)) (KAI1; OMIM:600623), which when mutated leads to disease.
31	F53B3.5	F53B3.5	n/a	chrX 2,876,207	F53B3.5 encodes a claudin homolog that may regulate ion channels; F53B3.5 is distantly similar to mammalian voltage-dependent calcium channel gamma subunits that are known or suspected to prevent epilepsy in vivo (e.g., stargazin; MGI:1316660); F53B3.5 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
32	E03H4.7	E03H4.7	n/a	chrI 12,422,814	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
33	F21D9.8	F21D9.8	n/a	chrV 19,279,623	contains similarity to Medicago truncatula Pectin methyl-esterase PER precursor (EC 3.1.1.11).; TR:Q9SC90
34	T26C11.4	T26C11.4	n/a	chrX 1,843,047	contains similarity to Dictyostelium discoideum Similar to Homo sapiens (Human). Dentin sialophosphoprotein [Contains:sDentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentinssialoprotein (DSP)].; TR:Q869X8
35	T06D8.2	T06D8.2	n/a	chrII 11,229,674	contains similarity to Pfam domain PF02151 UvrB/uvrC motif contains similarity to Interpro domains IPR009055 (UvrB, C-terminal UvrC-binding), IPR001943 (UvrB/UvrC protein)
36	K11H12.3	K11H12.3	n/a	chrIV 672,557	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
37	C04A11.2	C04A11.2	n/a	chrX 13,667,311	contains similarity to Homo sapiens Putative protein TPRXL; ENSEMBL:ENSP00000322097
38	str-38	T23D5.2	n/a	chrV 15,731,518	C. elegans STR-38 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
39	ceh-13	R13A5.5	n/a	chrIII 7,556,858	a homolog of Hox genes of labial/Hox1 type; affects viability, body shape and anterior patterning during embryogenesis, interacts genetically with hox genes; and is expressed in A, D, E and MS lineages in the early embryo, and in the anterior dorsal hypodermal cells, anterior body wall muscle cells, and in the cells of the prospective ventral nerve cord at the comma stage; and in the ventral nerve cord and and ventral and dorsal hypodermal cells in L1 larvae.
40	inx-6	C36H8.2	n/a	chrIV 12,748,113	inx-6 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; INX-6 is required for formation of pharyngeal gap junctions and thus for the electrical coupling and synchronous muscle contractions necessary for normal feeding behavior and postembryonic development; INX-6 may function redundantly with EAT-5, another C. elegans innexin; INX-6 expression is first detected in embryonic pharyngeal precursors and during later larval and adult stages, in pharyngeal corpus muscles and isthmus marginal cells, where INX-6 localizes to plaque-like structures in the plasma membrane.
41	C06C3.7	C06C3.7	n/a	chrII 9,385,835	contains similarity to Saccharomyces cerevisiae Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases (Mes1p and Ygl245wp), delivering tRNA to them, stimulating catalysis, and ensuring their localization to the cytoplasm; also binds quadruplex nucleic acids; SGD:YGL105W
42	C32B5.4	C32B5.4	n/a	chrII 980,130	contains similarity to Interpro domains IPR000931 (Adenovirus fibre protein), IPR008893 (WGR)
43	srx-45	K01B6.2	n/a	chrIII 9,305,269	C. elegans SRX-45 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
44	dhs-16	C10F3.2	n/a	chrV 5,984,592	dhs-16 encodes a short-chain dehydrogenase predicted to be mitochondrial.
45	B0198.2	B0198.2	n/a	chrX 12,030,645	contains similarity to Dictyostelium discoideum Non-receptor tyrosine kinase spore lysis A (EC 2.7.1.112) (Tyrosine-sprotein kinase 1).; SW:KYK1_DICDI
46	ugt-59	R11A8.3	n/a	chrIV 10,362,030	C. elegans UGT-59 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
47	ZC204.6	ZC204.6	n/a	chrII 1,644,534
48	F26D2.14	F26D2.14	n/a	chrV 16,436,268	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
49	T19C3.6	T19C3.6	n/a	chrIII 629,578
50	R160.6	R160.6	n/a	chrX 4,372,098