UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y57A10C.8	Y57A10C.8	0	chrII 12,428,881	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR002355 (Multicopper oxidase, copper-binding site)
2	R57.2	R57.2	n/a	chrX 298,212	contains similarity to Pfam domain PF01682 DB module contains similarity to Interpro domain IPR002602 (Protein of unknown function DB)
3	Y102A5C.27	Y102A5C.27	n/a	chrV 16,988,446	contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
4	Y39A1A.7	Y39A1A.7	n/a	chrIII 10,619,501	contains similarity to Sus scrofa Lymphocyte antigen 64-like protein.; TR:Q7YRL4
5	ZK896.9	ZK896.9	n/a	chrIV 12,857,434	ZK896.9 encodes a putative transporter of UDP-N-acetylglucosamine (UDP-GlcNAc) and UDP-N-acetylgalactosamine (UDP-GalNAc), orthologous to human SLC35A3 (OMIM:605632) and paralogous to C03H5.2 and SRF-3; ZK896.9 has no obvious function in RNAi assays, but this could reflect genetic redundancy with its paralogs.
6	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
7	C03A3.3	C03A3.3	n/a	chrX 11,268,134	contains similarity to Pfam domain PF00753 Metallo-beta-lactamase superfamily contains similarity to Interpro domain IPR001279 (Beta-lactamase-like)
8	F46F3.3	F46F3.3	n/a	chrV 11,668,418	contains similarity to Dictyostelium discoideum Hypothetical protein.; TR:Q86J27
9	lev-8	C35C5.5	n/a	chrX 11,562,231	lev-8 encodes a novel nicotinic acetylcholine receptor (nAChR) alpha subunit that is a member of the ACR-8 group of nAChR subunits; LEV-8 activity is required for normal rates of pharyngeal pumping and for fully wild-type responses (increased egg laying and body wall muscle contraction) to the nAChR agonist and antihelmintic levamisole; expression of a LEV-8::GFP reporter construct begins at the L1 larval stage and is detected in neurons, body wall and uterine muscle cells, and socket cells of the IL and OL mechanosensory neurons; expression in body wall muscles is strongest in the anterior, consistent with increased levamisole resistance of head, or anterior, muscles seen in lev-8 mutant animals.
10	hum-4	F46C3.3	n/a	chrX 11,426,926	hum-4 encodes a class XII myosin, an unconventional myosin.
11	Y43C5A.4	Y43C5A.4	n/a	chrIV 10,278,717	contains similarity to Interpro domain IPR000694 (Proline-rich region)
12	F35A5.5	F35A5.5	n/a	chrX 3,794,638	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR000976 (Wilm's tumour protein)
13	his-45	B0035.10	n/a	chrIV 11,326,794	his-45 encodes an H3 histone.
14	K04C1.3	K04C1.3	n/a	chrX 14,242,549	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR001766 (Fork head transcription factor)
15	C11G6.3	C11G6.3	n/a	chrX 16,343,288	contains similarity to Pfam domain PF00628 PHD-finger contains similarity to Interpro domains IPR001965 (Zinc finger, PHD-type), IPR000956 (Stathmin), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR003026 (Transcription factor Otx1, C-terminal), IPR000533 (Tropomyosin), IPR011011 (Zinc finger, FYVE/PHD-type)
16	C37E2.3	C37E2.3	n/a	chrX 14,180,268	contains similarity to Pfam domain PF04750 FAR-17a/AIG1-like protein contains similarity to Interpro domains IPR006838 (FAR-17a/AIG1-like protein), IPR002208 (SecY protein)
17	nhr-278	ZK6.1	n/a	chrV 409,173	C. elegans NHR-278 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000679 (Zinc finger, GATA-type), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
18	sas-5	F35B12.5	n/a	chrV 11,611,859	sas-5 encodes a coiled-coil protein whose activity is required, paternally, maternally, and in a dose-dependent manner, for daughter centriole formation; SAS-5 localizes to both the cytoplasm and to centrioles, and photobleaching experiments reveal rapid SAS-5 cycling between these two cellular components throughout the cell cycle; SAS-5 localization to centrioles depends upon the ZYG-1 kinase and the SAS-6 coiled-coil protein, two proteins also required for centriole duplication; in turn, SAS-5 activity is required for SAS-6 centriolar localization, as SAS-6 fails to localize properly in sas-5 mutant embryos.
19	T21E12.3	T21E12.3	n/a	chrI 4,403,989	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
20	srj-57	T03D3.14	n/a	chrV 2,854,982	C. elegans SRJ-57 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	srd-9	T09D3.1	n/a	chrV 5,352,409	C. elegans SRD-9 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like)
22	srh-23	C02E7.5	n/a	chrV 4,921,905	C. elegans SRH-23 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
23	srg-5	T12A2.11	n/a	chrIII 6,263,078	C. elegans SRG-5 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
24	R10E11.5	R10E11.5	n/a	chrIII 9,787,703	contains similarity to Homo sapiens cDNA FLJ77065, highly similar to Homo sapiens golgi autoantigen, golgin subfamily a, 4 (GOLGA4), mRNA; ENSEMBL:ENSP00000349305
25	let-23	ZK1067.1	n/a	chrII 9,202,659	let-23 encodes an EGF-receptor-family transmembrane tyrosine kinase that affects viability, inductive signaling during development of the vulva, male spicule formation, posterior development of the epidermis, ovulation and behavioral quiescience during lethargus; it is genetically upstream of the let-60/RAS pathway with respect to viability and vulval development, is upstream of phosopholipase C gamma with respect to fertility and quiesence, and is expressed in vulval precursor cells and the ALA neuron.
26	srd-69	H04J21.2	n/a	chrIII 2,364,601	C. elegans SRD-69 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	fbxb-53	F36H5.5	n/a	chrII 1,759,512	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
28	set-9	F15E6.1	n/a	chrIV 4,312,255	set-9 encodes a large (1,655-residue) protein with a low-complexity N-terminal region, followed by a PHD-zinc finger and a SET domain; SET-9 has no non-nematode orthologs, but has 96% identity (1616/1679 residues) to its paralog SET-26; SET-9 is required for a normally short lifespan and low spontaneous mutation rate; life extension by set-9(RNAi) requires DAF-16, indicating that SET-9 limits normal lifespan by negatively regulating DAF-16 (either directly or indirectly); otherwise, neither set-9(n4949) nor set-9(RNAi) have any obvious phenotypes.
29	fut-2	EGAP9.2	n/a	chrV 6,574,873	fut-2 encodes a unique alpha 1,2-fucosyltransferase specifically expressed in intestinal cells of larval and adult animals; recombinant FUT-2 expressed in human 293T cells exhibits a novel acceptor specificity profile compared with mammalian alpha 1,2-fucosyltransferases and the predicted protein shares very low amino acid identity with human alpha 1,2-fucosyltransferases, but its predicted type 2 topology and domain structure are typical of other glucosyltransferases.
30	T01G6.10	T01G6.10	n/a	chrV 502,683	contains similarity to Pfam domains PF01370 (NAD dependent epimerase/dehydratase family) , PF00106 (short chain dehydrogenase) contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR001509 (NAD-dependent epimerase/dehydratase), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
31	tsg-101	C09G12.9	n/a	chrIV 3,512,510	C09G12.9 encodes the C. elegans ortholog of S. cerevisiae vacuolar protein sorting protein Vps23p and human TUMOR SUSCEPTIBILITY GENE 101 (TSG101; OMIM:601387), mutations in which are associated with several types of cancer and with varying responses to HIV infection; the product of C09G12.9 is predicted to be a component of C. elegans ESCRT-1 (Endosomal Sorting Complex Required for Transport), and RNAi experiments indicate that its activity is essential for embryonic and larval development.
32	fbxb-9	C08F8.5	n/a	chrIV 11,161,021	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
33	nhr-44	T19A5.4	n/a	chrV 8,962,974	C. elegans NHR-44 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
34	ZC416.2	ZC416.2	n/a	chrIV 3,634,511	n/a
35	set-12	K09F5.5	n/a	chrX 7,734,685	set-12 encodes a putative histone H3 lysine-9 methyltransferase with no non-nematode orthologs; neither set-12(n4442) nor set-12(RNAi) have any obvious phenotypes.
36	C08H9.6	C08H9.6	n/a	chrII 9,873,847	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
37	F53B7.2	F53B7.2	n/a	chrV 10,993,353	F53B7.2 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that F53B7.2 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
38	fbxb-40	M01D1.9	n/a	chrII 1,049,413	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
39	F37E3.2	F37E3.2	n/a	chrI 6,427,369	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
40	srg-26	C10G8.1	n/a	chrV 5,332,145	C. elegans SRG-26 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
41	K01A11.1	K01A11.1	n/a	chrIII 3,429,872	contains similarity to Dictyostelium discoideum PAXILLIN-like protein.; TR:Q8MML5
42	che-3	F18C12.1	n/a	chrI 8,071,859	The dynein heavy chain (DHC) 1b isoform that affects the establishment and maintainance of the structural integrity of sensory cilia and also has a role in intraflagellar transport; it is expressed in ciliated sensory neurons.
43	D1086.1	D1086.1	n/a	chrV 14,099,606	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
44	ZK112.6	ZK112.6	n/a	chrIII 7,740,126	contains similarity to Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-sactivating enzyme).; SW:Q72LY9
45	nhr-255	ZK678.2	n/a	chrX 15,743,376	C. elegans NHR-255 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000679 (Zinc finger, GATA-type), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
46	M03B6.4	M03B6.4	n/a	chrX 13,859,911	contains similarity to Halobacterium sp Vng0659h.; TR:Q9HRK3
47	ZK892.6	ZK892.6	n/a	chrII 9,979,541	contains similarity to Vibrio parahaemolyticus Hypothetical protein.; TR:Q87PB2
48	K02E10.6	K02E10.6	n/a	chrX 2,481,834	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
49	ast-1	T08H4.3	n/a	chrII 4,131,358	ast-1 encodes a novel ETS-box transcription factor; AST-1 is required for the proper navigation of some interneuron axons to their targets, for differentiation of the ventral cord pioneer neuron AVG, and for pharyngeal morphogenesis; AST-1 is transiently expressed in many head neurons late in their differentiation and axon outgrowth, and in a few pharyngeal cells; AST-1 is at first nuclear, but then relocates to spots in cell bodies and even neuronal processes; hypomorphic ast-1 mutants have axons extending laterally, and crossing over from the right axon tract to the left axon bundle; null ast-1(hd92) mutants are inviable, failing to attach a working pharynx to their cuticle during development and then starving as L1 larvae; behaviorally, hypomorphic ast-1 animals are at least superficially normal, indicating that the ventral nerve cord can tolerate at least some miswiring; AST-1 regulates odr-2 expression, while ast-1 expression is itself regulated by lin-11.
50	Y76A2B.2	Y76A2B.2	n/a	chrIII 13,533,575	contains similarity to Homo sapiens Reticulon-4 receptor precursor; ENSEMBL:ENSP00000043402