UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	mcd-1	Y51H1A.6	0	chrII 13,891,577	mcd-1 encodes a highly acidic C2H2-type zinc-finger protein that, in conjunction with LIN-35/Rb, DPL-1/DP, EFL-1/E2F, LIN-37/Mip40, and LIN-52, promotes the developmentally programmed progression of cells through full apoptosis; MCD-1 can promote ectopic apoptosis in cells normally fated to live, and is thus active in such cells; MCD-1 is not required for CED-3-independent cell death, does not regulate CED-9, and probably does not transcriptionally regulate egl-1; MCD-1 and its partners do not act together with CED-1 or CED-8, and their function in cell death is distinct from the LET-60/RAS or SynMuv pathways; however, MCD-1 is redundantly required with some class B/C synMuv proteins for viability (LIN-9, LIN-35/Rb, or LIN-37/Mip40) and normally rapid growth (DPL-1/DP, LIN-13, LIN-53, LIN-54, or MYS-1); in mcd-1(n4005) animals, cells that would normally undergo apoptosis can instead pass through an episode of pre-apoptotic condensation, after which they sometimes revert to normal shape, survive, and differentiate; MCD-1 contains an N-terminal low-complexity region and a single central zinc-finger, but no other recognizable protein domains; MCD-1 is paralogous to Y48E1B.7, but has no obvious non-nematode orthologs.
2	srw-139	C44C3.7	n/a	chrV 2,984,742	C. elegans SRW-139 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
3	srd-56	E04F6.14	n/a	chrII 7,202,553	C. elegans SRD-56 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
4	ZC190.9	ZC190.9	n/a	chrV 8,692,862
5	Y79H2A.4	Y79H2A.4	n/a	chrIII 12,041,576	contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
6	W02B8.1	W02B8.1	n/a	chrII 13,900,226
7	srx-119	F49C5.1	n/a	chrII 12,528,893	C. elegans SRX-119 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
8	str-71	T23F1.4	n/a	chrV 15,458,547	C. elegans STR-71 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
9	Y49F6C.8	Y49F6C.8	n/a	chrII 3,369,682
10	C09G9.3	C09G9.3	n/a	chrIV 8,871,534	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
11	B0302.4	B0302.4	n/a	chrX 17,176,549
12	W09B6.5	W09B6.5	n/a	chrII 1,140,824
13	T27F6.7	T27F6.7	n/a	chrI 12,496,077	contains similarity to Timmia bavarica NADH dehydrogenase subunit 4 (Fragment).; TR:Q94YV9
14	sru-4	C33A12.10	n/a	chrIV 9,498,965	C. elegans SRU-4 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
15	C14E2.2	C14E2.2	n/a	chrX 1,808,144	contains similarity to Pfam domain PF00155 Aminotransferase class I and II contains similarity to Interpro domains IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR004839 (Aminotransferase, class I and II), IPR000796 (Aspartate/other aminotransferase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
16	F56H6.11	F56H6.11	n/a	chrI 12,309,058	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
17	B0391.3	B0391.3	n/a	chrV 15,616,248	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000802 (Arsenical pump membrane protein)
18	lin-11	ZC247.3	n/a	chrI 10,251,797	lin-11 encodes a predicted LIM homeodomain transcription factor that affects vulval development, neuronal development and fate specification, utse cell differentiation, and fertility; it is expressed in some neurons, the vulva, pi cells and their progeny, and the spermatheca.
19	sru-19	T04A11.8	n/a	chrIV 12,499,445	C. elegans SRU-19 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
20	smf-2	K11G12.3	n/a	chrX 6,717,366	C. elegans SMF-2 protein; contains similarity to Pfam domain PF01566 Natural resistance-associated macrophage protein contains similarity to Interpro domain IPR001046 (Natural resistance-associated macrophage protein)
21	Y75B8A.32	Y75B8A.32	n/a	chrIII 12,356,632	contains similarity to Danio rerio PERQ amino acid-rich with GYF domain-containing protein 2s(Trinucleotide repeat-containing gene 15 protein).; SW:Q4KME6
22	F33C8.2	F33C8.2	n/a	chrX 14,722,337	contains similarity to Interpro domain IPR003382 (Flavoprotein)
23	fbxa-112	Y102A5C.13	n/a	chrV 16,947,523	C. elegans FBXA-112 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
24	immp-1	C24H11.6	n/a	chrIII 11,775,731	C. elegans IMMP-1 protein; contains similarity to Pfam domain PF00717 Peptidase S24-like contains similarity to Interpro domains IPR001733 (Peptidase S26B, eukaryotic signal peptidase), IPR015927 (Peptidase S24, S26A, S26B and S26C), IPR014037 (Peptidase S26A), IPR011056 (Peptidase S24, S26A and S26B, C-terminal), IPR000223 (Peptidase S26A, signal peptidase I)
25	acbp-4	F56C9.5	n/a	chrIII 7,308,549	acbp-4 encodes an Acyl-CoA-binding protein.
26	srw-12	C41G6.2	n/a	chrV 15,237,968	C. elegans SRW-12 protein ;
27	srh-136	F36D3.6	n/a	chrV 16,496,767	C. elegans SRH-136 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
28	fbxa-113	Y113G7B.6	n/a	chrV 20,199,350	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
29	lrp-2	T21E3.3	n/a	chrI 3,939,445	C. elegans LRP-2 protein; contains similarity to Pfam domains PF00008 (EGF-like domain) (6), PF07974 (EGF-like domain) , PF00057 (Low-density lipoprotein receptor domain class A) (14), PF00058 (Low-density lipoprotein receptor repeat class B) (7)contains similarity to Interpro domains IPR000033 (), IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR001881 (EGF-like calcium-binding), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular), IPR015943 (WD40/YVTN repeat-like)
30	Y116A8C.15	Y116A8C.15	n/a	chrIV 16,996,337	contains similarity to Homo sapiens similar to KIAA1357 protein; ENSEMBL:ENSP00000258005
31	T05B4.13	T05B4.13	n/a	chrV 4,126,750	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
32	C31E10.1	C31E10.1	n/a	chrX 13,985,013	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000238 (Ribosome-binding factor A)
33	trxr-2	ZK637.10	n/a	chrIII 8,915,015	C. elegans TRXR-2 protein; contains similarity to Pfam domains PF02852 (Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain) , PF07992 (Pyridine nucleotide-disulphide oxidoreductase) , PF00070 (Pyridine nucleotide-disulphide oxidoreductase) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR000447 (FAD-dependent glycerol-3-phosphate dehydrogenase), IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR012999 (Pyridine nucleotide-disulphide oxidoreductase, class I, active site), IPR004099 (Pyridine nucleotide-disulphide oxidoreductase, dimerisation), IPR006338 (Thioredoxin and glutathione reductase selenoprotein), IPR016156 (FAD/NAD-linked reductase, dimerisation), IPR001327 (Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region), IPR000815 (Mercuric reductase), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
34	clec-120	F29A7.7	n/a	chrII 2,756,519	C. elegans CLEC-120 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold)
35	F29D10.2	F29D10.2	n/a	chrI 8,842,038	contains similarity to Interpro domains IPR000853 (Nematoda metallothionein, family 6), IPR000006 (Metallothionein, vertebrate), IPR002952 (Eggshell protein), IPR004035 (Endonuclease III, iron-sulphur binding, conserved site-1), IPR001396 (Echinodermata metallothionein, family 4), IPR001008 (Mollusc metallothionein, family 2)
36	F55E10.5	F55E10.5	n/a	chrX 8,335,538
37	D1007.9	D1007.9	n/a	chrI 4,591,009
38	F22E12.3	F22E12.3	n/a	chrV 10,461,278	contains similarity to Petroselinum crispum Reverse transcriptase (Fragment).; TR:Q9ZRL1
39	C30E1.8	C30E1.8	n/a	chrX 16,917,982	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
40	F48C1.3	F48C1.3	n/a	chrI 5,314,472
41	K05F6.8	K05F6.8	n/a	chrII 1,567,541	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
42	C03B1.10	C03B1.10	n/a	chrX 6,357,809	contains similarity to Homo sapiens cDNA FLJ42885 fis, clone BRHIP3007586; HI:HIT000044748
43	lis-1	T03F6.5	n/a	chrIII 13,373,822	lis-1 encodes an ortholog of human LIS1, which when mutated leads to lissencephaly (OMIM:247200); it also encodes an ortholog of the Aspergillus nidulans nudF, which mediates nuclear migration along Aspergillus hyphae.
44	C18G1.7	C18G1.7	n/a	chrV 4,746,815	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B), IPR008166 (Protein of unknown function DUF23)
45	R53.2	R53.2	n/a	chrII 9,964,971	contains similarity to Pfam domain PF02223 Thymidylate kinase contains similarity to Interpro domain IPR000062 (Thymidylate kinase)
46	Y45F10D.10	Y45F10D.10	n/a	chrIV 13,786,277	contains similarity to Pseudotylosurus angusticeps Recombination-activating protein 2 (Fragment).; TR:Q9DD51
47	T23F6.2	T23F6.2	n/a	chrIV 12,722,330
48	ZK185.1	ZK185.1	n/a	chrIV 4,550,393	contains similarity to Interpro domain IPR015880 (Zinc finger, C2H2-like)
49	Y75B8A.19	Y75B8A.19	n/a	chrIII 12,229,214	contains similarity to Lactococcus lactis Signal peptidase I (EC 3.4.21.89).; TR:Q9CDG2
50	sre-30	F57G9.2	n/a	chrII 12,405,637	C. elegans SRE-30 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)