UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y49F6C.2	Y49F6C.2	1e-72	chrII 3,379,231
2	glb-10	C29F5.7	n/a	chrII 6,308,800	glb-10 encodes a globin; glb-10 is expressed in pharynx, intestine, vulval muscle, and many neurons, with at least some subcellular localization to synapses; however, glb-10 has no obvious function in mass RNAi assays.
3	sri-57	F22E5.16	n/a	chrII 2,671,336	C. elegans SRI-57 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR003002 (7TM chemoreceptor, subfamily 1)
4	R03H4.1	R03H4.1	n/a	chrV 9,018,100	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
5	T25G3.4	T25G3.4	n/a	chrI 7,566,145	T25G3.4 encodes a putative mitochondrial glycerol-3-phosphate dehydrogenase, paralogous to Y50E8A.6 and orthologous to human GPD2 (OMIM:138430, mutated in type II diabetes mellitus); T25G3.4 transcripts are not obviously enriched during oogenesis, but T25G3.4 is predicted to be coexpressed in an operon with chs-1 and T25G3.3; such coexpression, if real, may simply reflect all three genes being required for oogenesis, rather than some more detailed functional connection; T25G3.4 has no obvious function in mass RNAi assays.
6	W10G6.1	W10G6.1	n/a	chrX 16,245,293	contains similarity to Babesia bovis Merozoite surface antigen-2a2.; TR:Q95UH0
7	F48C1.4	F48C1.4	n/a	chrI 5,313,536
8	Y26D4A.3	Y26D4A.3	n/a	chrI 13,072,492	contains similarity to Pfam domain PF00059 (Lectin C-type domain short and long forms)
9	Y43F8B.11	Y43F8B.11	n/a	chrV 19,471,547	contains similarity to Campylobacter coli CadF precursor (Outer membrane protein).; TR:O06895
10	srsx-8	F52F10.5	n/a	chrV 1,552,074	C. elegans SRSX-8 protein ;
11	srx-118	T21B4.12	n/a	chrII 12,526,763	C. elegans SRX-118 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
12	T06G6.5	T06G6.5	n/a	chrI 12,716,111	contains similarity to Interpro domain IPR007087 (Zn-finger, C2H2 type)
13	C07G1.7	C07G1.7	n/a	chrIV 8,211,372
14	tra-3	LLC1.1	n/a	chrIV 14,440,241	tra-3 encodes an atypical calpain regulatory protease that lacks calcium-binding EF hand domains; during development, TRA-3 likely promotes female development in XX hermaphrodites by cleaving the membrane-associated TRA-2A protein to generate a TRA-2 peptide likely to have feminizing activity; in addition, TRA-3 is one of several proteases that mediate necrotic cell death during neurodegeneration.
15	srw-103	ZK697.5	n/a	chrV 1,718,354	C. elegans SRW-103 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
16	lips-1	F45E6.4	n/a	chrX 12,494,285	C. elegans LIPS-1 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
17	srx-116	W05B10.5	n/a	chrV 12,671,795	C. elegans SRX-116 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
18	F53H2.3	F53H2.3	n/a	chrV 20,399,182	contains similarity to Interpro domain IPR006034 (Asparaginase/glutaminase)
19	T08G2.2	T08G2.2	n/a	chrX 17,207,313	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
20	Y50F7A.2	Y50F7A.2	n/a	chrII 1,183,626
21	F09C11.1	F09C11.1	n/a	chrIV 543,658
22	Y63D3A.4	Y63D3A.4	n/a	chrI 14,099,306	contains similarity to Pfam domain PF03372 Endonuclease/Exonuclease/phosphatase family contains similarity to Interpro domains IPR005637 (TAP, C-terminal), IPR009060 (UBA-like), IPR005135 (Endonuclease/exonuclease/phosphatase)
23	C17A2.5	C17A2.5	n/a	chrII 3,834,625	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
24	W05H5.1	W05H5.1	n/a	chrII 12,443,814	contains similarity to Ovis aries Lysophosphatidic acid receptor Edg-2 (LPA receptor 1) (LPA-1).; SW:EDG2_SHEEP
25	srh-235	F08E10.1	n/a	chrV 17,470,910	C. elegans SRH-235 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
26	dmd-3	Y43F8C.10	n/a	chrV 19,652,807	C. elegans DMD-3 protein; contains similarity to Pfam domain PF00751 DM DNA binding domain contains similarity to Interpro domain IPR001275 (DM DNA-binding)
27	F36D1.8	F36D1.8	n/a	chrI 11,257,879	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
28	T25G12.1	T25G12.1	n/a	chrX 17,249,457
29	Y32B12B.1	Y32B12B.1	n/a	chrV 16,536,916	contains similarity to Leptospira kirschneri serovar grippotyphosa Hypothetical protein.; TR:Q8KWV2
30	C15C8.5	C15C8.5	n/a	chrV 12,749,106	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
31	thoc-1	T02H6.2	n/a	chrII 705,367	C. elegans THOC-1 protein ; contains similarity to Danio rerio THO complex 1.; TR:Q7SYB2
32	fbxa-130	F42A6.8	n/a	chrIV 3,340,450	C. elegans FBXA-130 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
33	EGAP9.3	EGAP9.3	n/a	chrV 6,579,135	contains similarity to Pfam domain PF01531 Glycosyl transferase family 11 contains similarity to Interpro domain IPR002516 (Glycosyl transferase, family 11)
34	R04B3.2	R04B3.2	n/a	chrX 2,472,601	The R04B3.2 gene encodes an ortholog of the human gene LYSOSOMAL GLYCOSYLASPARAGINASE (AGA; OMIM:208400), which when mutated leads to aspartylglucosaminuria (OMIM:208400).
35	F55C5.1	F55C5.1	n/a	chrV 12,263,644	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
36	ram-5	T24C2.1	n/a	chrX 14,553,138	ram-5 encodes a novel transmembrane protein; during male tail development, ram-5 activity is required in ray structural cells for proper sensory ray morphogenesis; a RAM-5::GFP fusion protein is expressed in all of the ray structural cells of the male tail, as well as additional sensory support cells in both hermaphrodites and males, including those of the inner labial sensilla as well as the ADE, PDE, and phasmid socket cells.
37	T10E9.8	T10E9.8	n/a	chrI 6,540,502
38	C18G1.8	C18G1.8	n/a	chrV 4,765,470	contains similarity to Pfam domain PF01531 Glycosyl transferase family 11 contains similarity to Interpro domain IPR002516 (Glycosyl transferase, family 11)
39	Y116A8C.22	Y116A8C.22	n/a	chrIV 17,047,371	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR000116 (High mobility group proteins HMG-I and HMG-Y), IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
40	elp-1	F38A6.2	n/a	chrV 20,762,946	elp-1 encodes a WD repeat-containing protein that is the sole C. elegans EMAP (echinoderm microtubule-associated protein) homolog; ELP-1 binds microtubules in vitro, but as loss of ELP-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of ELP-1 in C. elegans development and/or behavior is not yet known; ELP-1 is expressed in many tissues, including body wall muscle, male-specific sex muscles, the vulva, spermatheca, sensory neurons, and intestinal cells.
41	R11.3	R11.3	n/a	chrX 16,198,339	contains similarity to Haemophilus influenzae Hypothetical protein HI0386.; SW:YBGC_HAEIN
42	mel-26	ZK858.4	n/a	chrI 9,134,137	mel-26 encodes a MATH and BTB/POZ domain-containing protein that functions as a novel substrate-specific adaptor of the CUL-3-containing E3 ubiquitin ligase; MEL-26 is required maternally for formation of mitotic spindles in the early embryo, and as a component of a ubiquitin ligase complex, for degradation of the microtubule-severing protein MEI-1 at the meiosis to mitosis transition; MEL-26 is also required maternally for embryonic morphogenesis; since MEL-26 contains a meprin-associated Traf homology (MATH) domain, it might be involved in apoptosis.
43	srh-37	R11G11.9	n/a	chrV 511,858	C. elegans SRH-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	nas-8	C34D4.9	n/a	chrIV 7,117,415	nas-8 encodes an astacin-like metalloprotease.
45	srz-90	C18D4.9	n/a	chrV 17,528,936	C. elegans SRZ-90 protein
46	frk-1	T04B2.2	n/a	chrIV 10,044,780	frk-1 encodes a non-receptor tyrosine kinase orthologous to the human proto-oncogene Fer; frk-1 is an essential gene required early for embryonic cell proliferation and later in embryonic epidermal cells for enclosure, morphogenesis and late stages of differentiation; FRK-1's role in embryonic development is independent of its kinase domain, and when expressed in cultured mammalian cells, FRK-1 disrupts cell adhesion; FRK-1 is initially expressed in all cells of the early embryo where it localizes to nuclei and points of cell-cell contact; later expression is seen in epithelial cells, body wall muscle, and the adult germline, including mature sperm; FRK-1 expression in epidermal cells requires activity of the ELT-1 GATA transcription factor, and FRK-1 localization to the plasma membrane requires PAT-3/Beta-integrin, JAC-1/p120 catenin, and HMP-2/Beta-catenin with which FRK-1 interacts in vitro.
47	srbc-58	R09E12.2	n/a	chrV 776,135	C. elegans SRBC-58 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
48	F15D4.6	F15D4.6	n/a	chrII 13,249,439	contains similarity to Bacillus halodurans Acetolactate synthase large subunit.; TR:Q9K8E5
49	W09H1.3	W09H1.3	n/a	chrII 13,184,626	contains similarity to Homo sapiens cDNA FLJ31139 fis, clone IMR322001185; ENSEMBL:ENSP00000380962
50	btb-5	W05G11.5	n/a	chrIII 60,257	C. elegans BTB-5 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)