UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	glrx-5	Y49E10.2	2e-61	chrIII 12,373,098	C. elegans GLRX-5 protein; contains similarity to Pfam domain PF00462 Glutaredoxin contains similarity to Interpro domains IPR002109 (Glutaredoxin), IPR014025 (Glutaredoxin subgroup), IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004480 (Glutaredoxin-related protein)
2	C50F2.3	C50F2.3	n/a	chrI 3,878,907	contains similarity to Pfam domain PF02184 HAT (Half-A-TPR) repeat contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR013212 (Mad3/BUB1 homology region 1), IPR003107 (RNA-processing protein, HAT helix)
3	F08A8.3	F08A8.3	n/a	chrI 12,948,957	contains similarity to Pfam domains PF01756 (Acyl-CoA oxidase) , PF02770 (Acyl-CoA dehydrogenase, middle domain) contains similarity to Interpro domains IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR012258 (Acyl-CoA oxidase), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR002655 (Acyl-CoA oxidase, C-terminal), IPR009075 (Acyl-CoA dehydrogenase/oxidase C-terminal)
4	clec-26	T20B3.12	n/a	chrV 16,849,392	C. elegans CLEC-26 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
5	cyp-25A2	C36A4.2	n/a	chrIII 3,836,163	C. elegans CYP-25A2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
6	mtss-1	PAR2.1	n/a	chrIII 8,768,640	C. elegans MTSS-1 protein; contains similarity to Pfam domain PF00436 Single-strand binding protein family contains similarity to Interpro domains IPR000424 (Primosome PriB/single-strand DNA-binding), IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold), IPR011344 (Single-strand DNA-binding)
7	F28A10.10	F28A10.10	n/a	chrII 831,531	contains similarity to Pfam domain PF01467 Cytidylyltransferase contains similarity to Interpro domains IPR004821 (Cytidyltransferase-related), IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold), IPR004820 (Cytidylyltransferase)
8	ncbp-1	F37E3.1	n/a	chrI 6,423,903	F37E3.1 encodes a putative nuclear cap-binding complex subunit ('CBP80') orthologous to budding yeast STO1 and human NCBP1 (OMIM:600469); in RNAi assays, F37E3.1 is required for embryonic and vulval development, normal locomotion, and general viability; by orthology to NCBP1, F37E3.1 is expected to participate in nonsense-mediated mRNA decay via a pioneer round of translation; F37E3.1(RNAi) induces expression of a gpdh-1::GFP transgene, perhaps because F37E3.1 prevents protein misfolding.
9	plc-4	R05G6.8	n/a	chrIV 7,511,060	C. elegans PLC-4 protein; contains similarity to Pfam domains PF00168 (C2 domain) , PF00387 (Phosphatidylinositol-specific phospholipase C, Y domain) , PF09279 (Phosphoinositide-specific phospholipase C, efhand-like) , PF00036 (EF hand) , PF00388 (Phosphatidylinositol-specific phospholipase C, X domain) contains similarity to Interpro domains IPR015359 (Phospholipase C, phosphoinositol-specific, EF-hand-like), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR001192 (Phospholipase C, phosphoinositol-specific, C-terminal (PLC)), IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type), IPR000909 (Phospholipase C, phosphatidylinositol-specific , X region), IPR001711 (Phospholipase C, phosphatidylinositol-specific, Y domain), IPR013841 (Phospholipase C, phosphatidylinositol-specific , X and Y boxes), IPR000008 (C2 calcium-dependent membrane targeting)
10	ZK593.1	ZK593.1	n/a	chrIV 10,911,466	contains similarity to Pfam domains PF02887 (Pyruvate kinase, alpha/beta domain) , PF00224 (Pyruvate kinase, barrel domain) contains similarity to Interpro domains IPR015806 (Pyruvate kinase, beta-barrel), IPR015794 (Pyruvate kinase, alpha/beta), IPR015795 (Pyruvate kinase, C-terminal-like), IPR015813 (Pyruvate/Phosphoenolpyruvate kinase, catalytic core), IPR001697 (Pyruvate kinase), IPR015793 (Pyruvate kinase, barrel)
11	K09E3.2	K09E3.2	n/a	chrX 17,117,739
12	K01A11.3	K01A11.3	n/a	chrIII 3,450,547	contains similarity to Pfam domain PF00443 (Ubiquitin carboxyl-terminal hydrolases family 2)
13	F56A11.5	F56A11.5	n/a	chrIV 569,608	contains similarity to Pfam domains PF03473 (MOSC domain) , PF03476 (MOSC N-terminal beta barrel domain) contains similarity to Interpro domains IPR005303 (MOSC, N-terminal beta barrel), IPR005302 (Molybdenum cofactor sulphurase, C-terminal), IPR001484 (Pyrokinin, conserved site), IPR011037 (Pyruvate kinase, beta-barrel-like)
14	ZK180.4	ZK180.4	n/a	chrIV 4,512,601	contains similarity to Pfam domains PF00025 (ADP-ribosylation factor family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR006687 (GTP-binding protein SAR1), IPR013684 (Miro-like), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR006688 (ADP-ribosylation factor), IPR006689 (ARF/SAR superfamily)
15	C04C3.3	C04C3.3	n/a	chrIV 3,401,683	contains similarity to Pfam domains PF02780 (Transketolase, C-terminal domain) , PF02779 (Transketolase, pyrimidine binding domain) contains similarity to Interpro domains IPR005476 (Transketolase, C-terminal), IPR005475 (Transketolase, central region), IPR015941 (Transketolase C-terminal-like)
16	F57G8.5	F57G8.5	n/a	chrV 16,340,228	contains similarity to Pfam domain PF00999 Sodium/hydrogen exchanger family contains similarity to Interpro domain IPR006153 (Sodium/hydrogen exchanger)
17	math-40	T08E11.3	n/a	chrII 1,831,237	C. elegans MATH-40 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
18	ppk-1	F55A12.3	n/a	chrI 5,361,848	ppk-1 encodes a putative phosphatidylinositol-4-phosphate 5' kinase that is essential for ovulation, intense gonad sheath contraction and dilation of the spermathecal valve during oocyte maturation, and UNC-54 filament organization; more generally, PPK-1 is required for fertility, progression through larval development, normal locomotion and defecation, and overall health; defects of ppk-1(RNAi) animals in sterility, ovulation, and UNC-54 filaments are suppressed by the gain-of-function itr-1(sy290) allele, presumably through increased IP(3) signalling; PPK-1 is expressed in gonad sheath, spermatheca, uterine and vulva muscles, distal tip cells, intestine, head mesodermal cell, and many neurons (e.g., in the ventral nerve cord, near the nerve ring, and in tail); PPK-1 may be activated by VAV-1; PPK-1 is orthologous to five human proteins (e.g., PIP5K1B, OMIM:602745), and distantly paralogous to PPK-2.
19	cdr-6	K01D12.12	n/a	chrV 12,413,079	C. elegans CDR-6 protein; contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR010987 (Glutathione S-transferase, C-terminal-like)
20	gly-3	ZK688.8	n/a	chrIII 7,916,183	gly-3 encodes an N-acetylgalactosaminyltransferase that is functional in vitro.
21	T09B4.9	T09B4.9	n/a	chrI 6,179,413	contains similarity to Pfam domain PF04280 Tim44-like domain contains similarity to Interpro domains IPR007379 (Mitochondrial import inner membrane translocase, subunit Tim44), IPR017303 (Import inner membrane translocase, TIM44 subunit, mitochondria), IPR005682 (Mitochondrial import inner membrane translocase, subunit Tim44, subtype)
22	F52G2.3	F52G2.3	n/a	chrIV 13,545,784	contains similarity to Pfam domain PF07547 RSD-2 N-terminal domain contains similarity to Interpro domain IPR011508 (RSD-2, N-terminal)
23	hlh-15	C43H6.8	n/a	chrX 2,413,123	C. elegans HLH-15 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
24	F25B4.5	F25B4.5	n/a	chrV 5,680,736	contains similarity to Interpro domain IPR003107 (RNA-processing protein, HAT helix)
25	F22G12.3	F22G12.3	n/a	chrI 13,153,129	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
26	C47E12.3	C47E12.3	n/a	chrIV 10,000,452	contains similarity to Pfam domain PF01532 Glycosyl hydrolase family 47 contains similarity to Interpro domain IPR001382 (Glycoside hydrolase, family 47)
27	F25E5.1	F25E5.1	n/a	chrV 7,468,526	contains similarity to Interpro domain IPR009091 (Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)
28	F19C7.1	F19C7.1	n/a	chrIV 4,606,991	contains similarity to Pfam domain PF06879 Protein of unknown function (DUF1261) contains similarity to Interpro domain IPR009673 (Protein of unknown function DUF1261)
29	B0205.6	B0205.6	n/a	chrI 10,738,293	contains similarity to Pfam domains PF01212 (Beta-eliminating lyase) , PF00266 (Aminotransferase class-V) contains similarity to Interpro domains IPR001597 (Aromatic amino acid beta-eliminating lyase/threonine aldolase), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR000192 (Aminotransferase, class V/Cysteine desulphurase), IPR016454 (Cysteine desulphurase, NifS), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
30	vpr-1	F33D11.11	n/a	chrI 5,869,119	C. elegans VPR-1 protein; contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein), IPR016763 (Vesicle-associated membrane protein)
31	nlt-1	ZK892.2	n/a	chrII 10,000,661	nlt-1 encodes a member of the SCP-2 sterol transfer family.
32	F21H12.6	F21H12.6	n/a	chrII 6,095,139	F21H12.6 encodes the C. elegans tripeptidyl peptidase II ortholog; loss of F21H12.6 activity via RNAi indicates that the product of F21H12.6 promotes fat formation; an F21H12.6::GFP reporter fusion is expressed in the intestine, the site of fat storage, and in a subset of nerve ring neurons.
33	oxi-1	Y39A1C.2	n/a	chrIII 10,862,495	C. elegans OXI-1 protein; contains similarity to Pfam domain PF00632 HECT-domain (ubiquitin-transferase) contains similarity to Interpro domain IPR000569 (HECT)
34	6R55.2	6R55.2	n/a	chrX 17,713,765
35	C49H3.8	C49H3.8	n/a	chrIV 7,901,218	contains similarity to Pfam domain PF00022 Actin contains similarity to Interpro domains IPR001478 (PDZ/DHR/GLGF), IPR004000 (Actin/actin-like), IPR013126 (Heat shock protein 70)
36	mrs-1	F58B3.5	n/a	chrIV 11,633,685	mrs-1 encodes a predicted cytoplasmic methionyl-tRNA synthetase (MetRS), a class I aminoacyl-tRNA synthetase that catalyzes the attachment of methionine to its cognate tRNA and is thus required for protein biosynthesis; MRS-1 is essential for embryogenesis and required also for a normal rate of postembryonic growth.
37	sec-10	C33H5.9	n/a	chrIV 7,780,928	C. elegans SEC-10 protein; contains similarity to Pfam domain PF07393 Exocyst complex component Sec10 contains similarity to Interpro domain IPR009976 (Exocyst complex component Sec10)
38	T14B4.1	T14B4.1	n/a	chrII 6,739,132
39	C02G6.1	C02G6.1	n/a	chrV 5,878,092	contains similarity to Pfam domains PF00675 (Insulinase (Peptidase family M16)) , PF05193 (Peptidase M16 inactive domain) (2)contains similarity to Interpro domains IPR001431 (Peptidase M16, zinc-binding site), IPR011765 (Peptidase M16, N-terminal), IPR011237 (Peptidase M16, core), IPR007863 (Peptidase M16, C-terminal), IPR011249 (Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)
40	ZK370.8	ZK370.8	n/a	chrIII 8,753,333	contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR013026 (Tetratricopeptide region)
41	elo-3	D2024.3	n/a	chrIV 7,238,796	The elo-3 gene encodes a paralog of elo-1 and elo-2, each of which encodes a polyunsaturated fatty acid (PUFA) elongase; ELO-3 may be required for normally rapid growth.
42	T08D2.1	T08D2.1	n/a	chrX 162,831	contains similarity to Pfam domain PF01105 emp24/gp25L/p24 family/GOLD contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR009038 (GOLD), IPR000348 (emp24/gp25L/p24)
43	nduf-2.2	T26A5.3	n/a	chrIII 6,466,129	T26A5.3 encodes a predicted mitochondrial protein whose mature sequence has near-identity (95%) to GAS-1; T26A5.3 transcription is detectable by RT-PCR, but not visible by promoter-GFP fusion; however, a transgene containing a fusion of the gas-1 promoter to the T26A5.3 protein-coding sequence is able to fully rescue gas-1 mutants, indicating that T26A5.3 encodes a fully functional mitochondrial 49 kDa subunit that may rescue gas-1(fc21) mutants from lethality; mutants homozygous for a T26A5.3 deletion have normal anesthetic sensitivity and normal sensitivity to oxygen (unlike gas-1 mutants) but a shortened lifespan at normal laboratory oxygen levels (20%); animals doubly mutant for gas-1 and T26A5.3 have maternal-effect lethality, but sterile surviving parents are abnormally long-lived (2.7 times longer than wild-type and 4.2 times longer than gas-1 mutants); double mutants remain hypersensitive to oxygen.
44	F35C11.4	F35C11.4	n/a	chrII 8,250,751	contains similarity to Homo sapiens Uncharacterized protein C9orf125; ENSEMBL:ENSP00000363980
45	gta-1	K04D7.3	n/a	chrIV 10,182,270	The gta-1 gene encodes an ortholog of the human gene GABAT, which when mutated leads to GABA-transaminase deficiency (OMIM:137150).
46	dhp-2	C47E12.8	n/a	chrIV 9,979,451	The dhp-2 gene encodes an ortholog of the human gene DIHYDROPYRIMIDINASE (DPYS), which when mutated leads to dihydropyrimidinuria (OMIM:222748).
47	srh-177	K02E2.3	n/a	chrV 20,363,754	C. elegans SRH-177 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
48	F48C1.6	F48C1.6	n/a	chrI 5,318,763
49	ctg-2	T13H5.2	n/a	chrII 8,515,897	C. elegans CTG-2 protein; contains similarity to Pfam domains PF01105 (emp24/gp25L/p24 family/GOLD) , PF00650 (CRAL/TRIO domain) contains similarity to Interpro domains IPR001071 (Cellular retinaldehyde binding/alpha-tocopherol transport), IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal), IPR009038 (GOLD), IPR011074 (Phosphatidylinositol transfer protein-like, N-terminal), IPR000348 (emp24/gp25L/p24)
50	cif-1	K08F11.3	n/a	chrIV 4,708,690	C. elegans CIF-1 protein; contains similarity to Pfam domain PF01399 PCI domain contains similarity to Interpro domain IPR000717 (Proteasome component region PCI)