UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	sas-6	Y45F10D.9	0	chrIV 13,787,798	sas-6 encodes a protein that contains a coiled-coil region and a novel PISA (present in SAS-6) motif which is conserved in similar proteins in at least eight other species that contain basal bodies or centrioles; SAS-6 activity, along with that of ZYG-1, SAS-4, SAS-5, and SPD-2, is essential for centriole duplication; SAS-6 functions in a dose-dependent manner and localizes to centriolar cylinders; SAS-6 co-localizes to centrioles with SAS-4 and SAS-5, and is mutually dependent upon SAS-5, with which it interacts physically, for centriolar localization; SAS-6 localization also requires the activity of the ZYG-1 kinase; in addition to the early embryo, SAS-6 is also detected in sperm.
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	nhr-90	ZK488.2	n/a	chrV 611,490	C. elegans NHR-90 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
4	ceh-7	C34C6.8	n/a	chrII 8,703,530	ceh-7 encodes a homeodomain transcription factor; expressed in cells around the rectum of the male tail.
5	C55C3.2	C55C3.2	n/a	chrIV 5,707,741
6	cut-5	R07E3.3	n/a	chrX 10,336,033	C. elegans CUT-5 protein; contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
7	B0554.3	B0554.3	n/a	chrV 434,275
8	F22F7.3	F22F7.3	n/a	chrV 2,113,100	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
9	srh-300	Y94A7B.6	n/a	chrV 17,822,964	C. elegans SRH-300 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
10	C06A5.5	C06A5.5	n/a	chrI 5,982,136
11	F41E7.7	F41E7.7	n/a	chrX 10,311,728	contains similarity to Drosophila grimshawi Chorion protein S18.; SW:CH18_DROGR
12	F59C6.8	F59C6.8	n/a	chrI 10,511,155	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
13	mab-5	C08C3.3	n/a	chrIII 7,780,108	mab-5 encodes a homeodomain transcription factor related to the Antennapedia, Ultrabithorax, and abdominal-A family of homeodomain proteins; during postembryonic development, mab-5 is required cell autonomously for specification of posterior cell fates, including hypodermal and neuronal fates, programmed cell deaths, cell proliferation and migration, and fate specification of the male-specific copulatory muscles and sensory rays; in addition, ectopic expression of mab-5 is sufficient to alter cell fates, such as direction of migration or sensory ray identity; in regions of the body where mab-5 expression overlaps with that of lin-39, another C. elegans HOM-C gene, the two genes appear to either compensate for one another's activity or act combinatorially to promote cell fates distinct from those where either gene is expressed alone; a mab-5:lacZ reporter fusion is expressed in cells in the posterior body region from the mid-gastrulation stage of embryogenesis through larval and adult stages; further, antibody staining reveals that MAB-5 expression in the V5 lineage is dynamic, switching on and off several times, while expression in V6 is continuous throughout most of the L1-L3 larval stages; early MAB-5 expression is V6 is dependent upon wild-type activity of pal-1, which encodes the C. elegans Caudal ortholog.
14	C12D12.3	C12D12.3	n/a	chrX 3,490,216
15	ace-4	Y48B6A.7	n/a	chrII 14,201,652	ace-4 encodes an divergent acetylcholinesterase homolog with biochemically undetectable activity.
16	K12H6.10	K12H6.10	n/a	chrII 2,822,965
17	hot-5	K07A12.6	n/a	chrI 8,685,157	hot-5 encodes a predicted membrane-associated protein that is a member of the Ly-6 superfamily of glycosylphosphatidylinositol (GPI)-linked signaling proteins and is homologous to ODR-2, a neuronally expressed protein required for olfaction; as loss of hot-5 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of HOT-5 in C. elegans development and/or behavior is not yet known.
18	unc-46	C04F5.3	n/a	chrV 5,098,120	unc-46 encodes a novel protein with a single predicted transmembrane domain; UNC-46 and UNC-47, a novel transmembrane vesicular GABA transporter, are required in GABAergic neurons for all GABA neurotransmission, specifically for loading of GABA into synaptic vesicles, where UNC-46 is localized; UNC-46 localization requires UNC-47, which when overexpressed can rescue unc-46 mutant animals.
19	fip-3	C06E1.5	n/a	chrIII 8,589,320	C. elegans FIP-3 protein ;
20	F11A5.3	F11A5.3	n/a	chrV 16,195,214	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras)
21	sri-45	K07E8.9	n/a	chrII 660,949	C. elegans SRI-45 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	math-32	F59H6.4	n/a	chrII 2,012,019	C. elegans MATH-32 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
23	F10E7.1	F10E7.1	n/a	chrII 7,127,780	contains similarity to Pfam domain PF06542 Protein of unknown function (DUF1114) contains similarity to Interpro domain IPR009497 (Protein of unknown function DUF1114)
24	ceh-16	C13G5.1	n/a	chrIII 8,624,237	ceh-16 encodes a homeodomain protein orthologous to Drosophila and vertebrate Engrailed proteins involved in segment and appendage development; ceh-16 is an essential gene required for proper specification and differentiation of the lateral seam cells during embryonic development; in specifying seam cell fates, CEH-16 appears to act as a transcriptional regulator, repressing expression of the eff-1 gene required for cell fusion and inducing expression of seam cell-specific genes such as elt-5/GATA, nhr-73, and nhr-74; a rescuing CEH-16::GFP fusion protein is first expressed in the early embryo in cells of the AB lineage; in later embryonic stages CEH-16::GFP is seen in all lateral seam cell nuclei as well as in some anterior neurons; during postembryonic development, CEH-16::GFP is expressed in the DA1 and DD1 motorneurons.
25	ZC84.3	ZC84.3	n/a	chrIII 9,188,742	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
26	fbxa-220	Y66A7A.1	n/a	chrIII 11,483,373	C. elegans FBXA-220 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
27	eat-4	ZK512.6	n/a	chrIII 9,139,280	eat-4 encodes an ortholog of the mammalian BNPI vesicular glutamate transporter that affects chemotaxis, feeding, foraging and thermotaxis; eat-4 is expressed in specific neurons, including M3L and M3R which are known to be glutamatergic.
28	srh-179	ZK228.7	n/a	chrV 18,477,190	C. elegans SRH-179 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
29	clec-202	C30H6.4	n/a	chrIV 17,362,968	C. elegans CLEC-202 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
30	C29F9.1	C29F9.1	n/a	chrIII 133,396
31	F23B2.7	F23B2.7	n/a	chrIV 9,151,248	contains similarity to Homo sapiens similar to Cylicin I (Multiple-band polypeptide I); ENSEMBL:ENSP00000331556
32	srw-10	ZC482.6	n/a	chrIII 12,755,860	C. elegans SRW-10 protein ;
33	F56C3.9	F56C3.9	n/a	chrX 1,392,907	contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR013089 (Kelch related)
34	Y57A10B.2	Y57A10B.2	n/a	chrII 12,376,431	contains similarity to Homo sapiens RNA binding protein; ENSEMBL:ENSP00000301740
35	C12D8.9	C12D8.9	n/a	chrV 10,242,987	contains similarity to Oceanobacillus iheyensis Hypothetical protein.; TR:Q8ELE1
36	clec-201	C30H6.3	n/a	chrIV 17,359,724	C. elegans CLEC-201 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
37	srh-69	T21B4.7	n/a	chrII 12,514,088	C. elegans SRH-69 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
38	F45E6.3	F45E6.3	n/a	chrX 12,488,021	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
39	F54F3.3	F54F3.3	n/a	chrV 12,920,812	contains similarity to Pfam domains PF04083 (ab-hydrolase associated lipase region) , PF00561 (alpha/beta hydrolase fold) contains similarity to Interpro domains IPR006693 (AB-hydrolase associated lipase region), IPR000073 (Alpha/beta hydrolase fold-1), IPR008262 (Lipase, active site)
40	ocr-2	T09A12.3	n/a	chrIV 8,216,912	ocr-2 encodes a TRPV (transient receptor potential channel, vanilloid subfamily) ion channel; OCR-2 activity is required for several types of sensory transduction including olfaction, osmosensation, mechanosensation, and chemosensation; an OCR-2 fusion protein is expressed in sensory cilia and requires the OSM-9 TRPV channel protein for proper localization; likewise, OSM-9 requires OCR-2 for its cilial localization.
41	nhr-172	C54F6.9	n/a	chrV 7,509,779	C. elegans NHR-172 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR015880 (Zinc finger, C2H2-like), IPR001781 (Zinc finger, LIM-type), IPR007087 (Zinc finger, C2H2-type)
42	C17G1.5	C17G1.5	n/a	chrX 9,943,135	contains similarity to Hepatitis C virus Non-structural protein 5b (Genome polyprotein) (Fragment).; TR:Q8V1C2
43	nhr-251	ZK488.4	n/a	chrV 601,466	C. elegans NHR-251 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
44	ham-1	F53B2.6	n/a	chrIV 12,543,852	ham-1 encodes a novel protein with a winged helix DNA-binding motif; ham-1 is required for the asymmetric divisions of several neuroblasts in the developing embryo and may influence their spindle position; ham-1 mutations also exhibit HSN motor neuron migration defects; HAM-1 interacts with itself in a yeast two-hybrid screen and observations suggest that its multimerization is required for its proper localization; HAM-1 is cytoplasmic and is asymmetrically distributed to the posterior of the HSNPHB neuroblast.
45	Y32B12A.1	Y32B12A.1	n/a	chrV 16,488,780	contains similarity to Pfam domain PF00569 Zinc finger, ZZ type contains similarity to Interpro domain IPR000433 (Zinc finger, ZZ-type)
46	str-47	F07C4.1	n/a	chrV 7,646,392	C. elegans STR-47 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
47	sre-54	C50E10.6	n/a	chrII 12,333,899	C. elegans SRE-54 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000366 (Fungal pheromone mating factor STE2 GPCR)
48	ceh-17	D1007.1	n/a	chrI 4,569,495	ceh-17 encodes a phox-2-like homeodomain protein that is a member of the Q50 paired-like class of homeobox proteins and the vertebrate orthologue of Phox2a and Phox2b; that affects ALA and SIA axonal development; ceh-17 affects ALA and SIA antero-posterior axonal growth and navigation, and is expressed in five neurons of the ring ganglia (ALA and the 4 SIAs) with strongest expression in embryos and in L1 stage larvae.
49	C49F5.5	C49F5.5	n/a	chrX 11,986,477	contains similarity to Pfam domain PF02135 TAZ zinc finger contains similarity to Interpro domain IPR000197 (Zinc finger, TAZ-type)
50	F25H9.2	F25H9.2	n/a	chrV 13,458,772	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)