UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y43E12A.2	Y43E12A.2	1e-137	chrIV 10,983,505	contains similarity to Interpro domain IPR001878 (Zinc finger, CCHC-type)
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	C08G5.5	C08G5.5	n/a	chrII 756,602	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003882 (Pistil-specific extensin-like protein)
4	nit-1	ZK1058.6	n/a	chrIII 3,923,096	C. elegans NIT-1 protein; contains similarity to Pfam domain PF00795 Carbon-nitrogen hydrolase contains similarity to Interpro domains IPR003010 (Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase), IPR000132 (Nitrilase/cyanide hydratase, conserved site)
5	K07G5.4	K07G5.4	n/a	chrI 7,167,846	contains similarity to Interpro domain IPR002048 (Calcium-binding EF-hand)
6	ZK180.1	ZK180.1	n/a	chrIV 4,497,817	contains similarity to Pfam domain PF00003 7 transmembrane receptor (metabotropic glutamate family) contains similarity to Interpro domains IPR000337 (GPCR, family 3), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B)
7	maa-1	C18D11.2	n/a	chrIII 11,821,012	maa-1 encodes a novel, transmembrane acyl-CoA-binding protein; maa-1 activity, together with that of rme-1, is required for normal rates of endosomal recycling and for proper endosomal shape and morphology; a rescuing MAA-1::GFP fusion protein is expressed in the hypodermis (excluding the seam cells) and the intestine, as well as in an area near the dorsal and ventral nerve cords; within the hypodermis and intestine, MAA-1::GFP localizes to endosomal and Golgi vesicle membranes.
8	sru-24	F31F4.13	n/a	chrV 669,671	C. elegans SRU-24 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domains IPR003839 (Protein of unknown function DUF215), IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
9	C50A2.2	C50A2.2	n/a	chrIV 1,173,690	contains similarity to Interpro domains IPR000953 (Chromo domain), IPR016197 (Chromo domain-like)
10	F07G6.5	F07G6.5	n/a	chrX 1,706,500
11	lgc-4	F18G5.4	n/a	chrX 9,238,639	C. elegans LGC-4 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR002394 (Nicotinic acetylcholine receptor, N-terminal), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
12	ZK688.2	ZK688.2	n/a	chrIII 7,902,682	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
13	F17C8.6	F17C8.6	n/a	chrIII 4,745,411	F17C8.6 encodes an alpha1 Ca2+ channel subunit; large-scale RNAi experiments indicate that during development F17C8.6, along with nca-2, may play a role in regulating egg size and shape.
14	R10E4.3	R10E4.3	n/a	chrIII 4,286,638	contains similarity to Saccharomyces cerevisiae Mlp proteins restrict telomere length by influencing the Rif1-Tel1 pathway of telomerase regulation; also involved in the translocation of macromolecules between the nucleoplasm and the NPC; SGD:YIL149C
15	F55G11.7	F55G11.7	n/a	chrIV 12,961,290	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
16	C46A5.1	C46A5.1	n/a	chrIV 7,765,495	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
17	T21D12.12	T21D12.12	n/a	chrIV 267,384	contains similarity to Pfam domain PF00014 Kunitz/Bovine pancreatic trypsin inhibitor domain contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR006150 (Cysteine-rich repeat)
18	btb-1	F40G9.4	n/a	chrIII 186,286	C. elegans BTB-1 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
19	nep-2	T05A8.4	n/a	chrII 2,721,578	T05A8.4 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; while T05A8.4 is an ortholog of mammalian neutral endopeptidase (NEP), expressed on the brush-border membranes of kidney; more generally, T05A8.4 falls into a group of proteins that includes the classical neprilysins found in mammals (e.g., PEX [OMIM:307800] and the enkephalin cleaving enzymes).
20	W05B5.2	W05B5.2	n/a	chrI 13,052,842	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002286 (P2 purinoceptor), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
21	F38H4.3	F38H4.3	n/a	chrIV 11,845,293	contains similarity to Interpro domain IPR000694 (Proline-rich region)
22	C30F2.3	C30F2.3	n/a	chrX 16,084,008	contains similarity to Dictyostelium discoideum Putative uncharacterized protein.; TR:Q1MVQ9
23	F25F6.1	F25F6.1	n/a	chrX 4,445,262
24	B0238.13	B0238.13	n/a	chrV 5,245,859	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
25	nhr-180	F31F4.12	n/a	chrV 666,725	C. elegans NHR-180 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
26	del-1	E02H4.1	n/a	chrX 14,274,420	del-1 encodes an ion channel protein of the DEG/ENaC (degenerin/epithelial Na+ channel) family; like other members of the degenerin family, DEL-1 is predicted to function as a sensory mechanotransduction channel, however detailed analysis of the DEL-1 mutant phenotype has not yet been reported; DEL-1 is expressed postembryonically in the VA and VB motor neurons and in the FLP sensory neurons; the DEL-1 expression pattern overlaps that of UNC-8, an additional C. elegans degenerin involved in movement control, with which DEL-1 may coassemble to form mechanically activated cation channels.
27	ZK1067.4	ZK1067.4	n/a	chrII 9,211,645	ZK1067.4 is orthologous to the human gene PROTEOLIPID PROTEIN 1 (PLP1; OMIM:300401), encoding the primary constituent of myelin, which when mutated leads to Pelizaeus-Merzbacher disease (OMIM:312080).
28	C29F9.6	C29F9.6	n/a	chrIII 115,990	contains similarity to Pfam domain PF02135 TAZ zinc finger contains similarity to Interpro domains IPR003101 (Coactivator CBP, KIX), IPR000197 (Zinc finger, TAZ-type)
29	F19B2.6	F19B2.6	n/a	chrV 20,155,401	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q23A89
30	T24D5.2	T24D5.2	n/a	chrX 12,585,041	contains similarity to Plasmodium falciparum DNA-directed RNA polymerase beta chain (EC 2.7.7.6).; SW:RPOB_PLAFA
31	C06A5.10	C06A5.10	n/a	chrI 5,982,746
32	F40F9.8	F40F9.8	n/a	chrV 9,734,765	contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
33	F32H5.4	F32H5.4	n/a	chrV 13,362,228	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
34	F58G1.8	F58G1.8	n/a	chrII 12,925,362	contains similarity to Interpro domain IPR009022 (Elongation factor G, III and V)
35	ZK262.3	ZK262.3	n/a	chrV 18,415,571	contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domains IPR002921 (Lipase, class 3), IPR008262 (Lipase, active site)
36	W04C9.5	W04C9.5	n/a	chrI 464,897	contains similarity to Pfam domain PF00071 Ras family contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
37	del-4	T28B8.5	n/a	chrI 8,140,996	C. elegans DEL-4 protein; contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
38	F56D5.3	F56D5.3	n/a	chrIV 9,400,450	contains similarity to Pfam domain PF00724 NADH:flavin oxidoreductase / NADH oxidase family contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001155 (NADH:flavin oxidoreductase/NADH oxidase, N-terminal), IPR002343 (Paraneoplastic encephalomyelitis antigen)
39	T03D8.2	T03D8.2	n/a	chrV 20,833,812	contains similarity to Pfam domain PF00164 Ribosomal protein S12 contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR006032 (Ribosomal protein S12/S23), IPR012340 (Nucleic acid-binding, OB-fold), IPR005679 (Ribosomal protein S12, bacterial-type)
40	R09H10.1	R09H10.1	n/a	chrIV 10,601,257	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
41	M117.3	M117.3	n/a	chrIV 11,823,697	M117.3 can encode a protein with similarity to the C-terminal half of the 14-3-3 proteins PAR-5 and FTT-2, beginning in predicted alpha helix five and continuing through the ends of the proteins; loss of M117.3 activity via large-scale RNAi results in no obvious abnormalities.
42	C01G6.7	C01G6.7	n/a	chrII 9,292,949	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
43	K03H6.1	K03H6.1	n/a	chrIV 1,525,035	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
44	sri-10	C54E10.4	n/a	chrV 18,805,260	C. elegans SRI-10 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR016040 (NAD(P)-binding)
45	D2023.3	D2023.3	n/a	chrV 11,804,015	contains similarity to Pfam domain PF00168 C2 domain contains similarity to Interpro domains IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
46	cyp-13A8	T10B9.4	n/a	chrII 9,806,501	C. elegans CYP-13A8 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
47	lact-3	M28.6	n/a	chrII 10,654,998	lact-3 encodes a beta-lactamase domain-containing protein that contains a predicted signal sequence; loss of lact-3 activity via RNAi has been reported to result in reduced fat content.
48	F16G10.11	F16G10.11	n/a	chrII 2,392,784	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
49	jph-1	T22C1.7	n/a	chrI 7,948,882	jph-1 encodes a junctophilin, a protein that belongs to a transmembrane family of proteins implicated in the formation of the junctional membrane complex that forms between the plasma membrane and the endoplasmic reticulum in excitable cells; this complex facilitates cross-talk between the cell surface and intracellular ionic channels; RNA interference of jph-1 results in a locomotion defect suggesting impaired body-wall muscle function; a jph-1 promoter-gfp fusion reporter is expressed in all muscle cells and certain neurons of the nerve ring.
50	B0207.11	B0207.11	n/a	chrI 5,963,581	B0207.11 encodes a nematode-specific protein probably required for a normally high ovulation rate; B0207.11 has no obvious non-nematode homologs, but does have a putative N-terminal coiled-coil domain and an SH2 motif, and is is paralogous to four other C. elegans proteins (F42G4.6, F44F4.10, T08G11.2, and Y81G3A.1); B0207.11(tm322) hermaphrodites show abnormal egg-laying, retaining significantly fewer eggs than wild-type (perhaps due to a lowered ovulation rate) while retaining late-stage embryos; B0207.11 has no obvious phenotype in mass RNAi experiments, possibly because of genetic redundancy with its paralogs.